Gene DRAK2 (Human)

DRAK2

Species: Human
Alias: DRAK2, STK17B
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 2q32.3-q33,

Classification

Group: CAMK
Family: DAPK
Subfamily: DRAK

Sequence

Name Sequence Type Origin Length Description Download
DRAK2.NA RNA Sugen Kinome 5324 None Fasta, JSON
DRAK2.AA Protein Sugen Kinome 372 None Fasta, JSON
DRAK2.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of DRAK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DRAK2.AA DAPK 35-293 61 6.1e-241 671.78 In-house 1-264 (264) Show / Hide 
Range on Protein: 35-293
Range on HMM: 1-264/264
Sequence Identity: 61% (163 aa)

TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQD----CRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMV
...|||||.|||||.|..||||..|||||.|||||||.    ||.||.||||.||.....|.|||||||||.....||||||..|||.|..|.....|..
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

SENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSS-IYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLL
.|.|..|..|||||||.|||..||.|||||||||.|.. ..|.|||||.|||.||||....|.|.|||||||.||||.||.|...|||||.||.|.|..|
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML

THTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
...|||.|...|||.|||||||.|.|||.||..|..|.|||..||||.||||.||| ||.|.|.
SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI
Kinase DRAK2.AA DRAK 35-293 71 2.6e-218 685.9 In-house 1-259 (259) Show / Hide 
Range on Protein: 35-293
Range on HMM: 1-259/259
Sequence Identity: 71% (184 aa)

TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND
|.||.|||||||||.||.|.|||..||||.||||||||||.|||||||||.|...||.|||||||||..||.||.||||||||||..|.....|...|.|
TAKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKD

VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP
|.|...||||||.||||.||||||||||||||.|.||..||||.||||||.|....|.|||||||.|.|||||||||||.|||||.||...|..|||.||
VQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISP

FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
|||.|.|||.|||||.|.|||||.||..|..|.||||||.|..||.|.|||.||.|.||
FVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL
Kinase DRAK2.AA MLCK 32-293 42 2.5e-125 332.21 In-house 1-257 (257) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-257/257
Sequence Identity: 42% (114 aa)

YILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVS
|. . .||||||| .|. || ||||...|||| | |..    ......|| ..      |..|..|. .|...|...|.||  |||.|   . |  .. .
YQIH-EELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKD--KENVKNEIEIMNQL-HHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHL-T

ENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSS---IYPLGDIKIVDFGMSRKIGHACE-LREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYM
| .||. ..||.||| ..|..|||||||||.||.. .   .    .|||.|||  ||.  . . ..   ||||..|||. ||||....|||| .| |.||
EREVIHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSH----QIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYM

LLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
||.  ||| |....||. |.. .. |. .|.|  .|. |.|||  ||||..|||.||. || | ||
LLSGLSPFMGDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL
Kinase DRAK2.AA DAPK 35-293 47 2.3e-120 348.91 In-house 3-264 (264) Show / Hide 
Range on Protein: 35-293
Range on HMM: 3-264/264
Sequence Identity: 47% (126 aa)

TSKELGRGKFAVVRQCISKSTGQEYAAKFLKKR-----RRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEM
.  |.| | ||||. |  ||||.|||||| |||     |||  .| .|  |. .|.  .  | .| ||.|||| ....||||  .||| |     .  | 
MGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGV-SREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEK--EC

VSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYML
..|      |||||.||...|  .|.|.|||| || ||    |   |||.|||....|    | ..|.||||. |||| || |   .|||| ||.| | |
LNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYIL

LTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
|   ||| |.  |||  ||. || ...|| |.. |..| |||  |||| |.|| | . || |.| 
LSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI
Kinase DRAK2.AA CAMK 38-293 22 8.9e-105 338.61 In-house 1-425 (425) Show / Hide 
Range on Protein: 38-293
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

ELGRGKFAVVRQCISKSTG------------QEYAAKFLKKRRRG--------------------------QDCRAEILHEIAVLELAK------SCPRV
.|||| |..|. || |.|.            |..|.|...|..                            .  |.....||... . .      . | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INLHEVYEN-------------------TSEIILIL---EYAAGGEIFSLCLPELAEM-----------------VSENDVIRLIKQILEGVYYLHQNNI
|.|.||||.                   ........   ||. ||| |  ..  . |                  ..| .. |...||...| |.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHLDLKPQNILLSSIYPL--------------GDIKIVDFGMSRKIGHAC------------------------ELREIMGTPEYLA-PEILNY------
||.|||| ||||.. ..               ..|||.|||...|. .                           ...  ||||| | ||.||.      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DPITTATDMWNIGIIAYMLLTHTSPFVGE-------------DNQETYLNISQVNVDYSEETFSSVS--------------------QLATD
        .... ..||| .|.| |..|. ..|| |.             . .|.. .| . . |. .. || .|                    | . |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FIQSLLVKNPEKRPTAEICLSHSWL
.|...|...||||.|.| ||.| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DRAK2.AA Trio 31-293 36 3.3e-103 265.32 In-house 1-258 (258) Show / Hide 
Range on Protein: 31-293
Range on HMM: 1-258/258
Sequence Identity: 36% (98 aa)

FYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAE--
. ...  |.||| |.|||.|. |.|| . ||||  .| ..   ..  .|| ..|  . . |.|. ||. ||     ||||| . .||.    |. |..  
YTFQE--EIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMD---KEQVYHEYEMLQ-HLQHPCVCSLHDTYETPRHYILILELCDDGEL----LCCLMRWG

MVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYP-LGDIKIVDFGMSRKIGHA--CELREIMGTPEYLAPEILNYDPITTATDMWNIGIIA
 ..| .|.  . |.||.| |||.. | |||.|| |...    .   .|||.|||   ..  .    . .  |.||  ||||.. .|.  .|| | || ..
SYCESEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLT

YMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
| .|.  |||..|. .|| .||  .... .|..| .||| |..||...|.  | |||.|. ||.| |.
YVMLSGISPFYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF
Kinase DRAK2.AA S_TKc 33-293 28 3.9e-79 270.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

ILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG--GEIFSLCLPELA---
    ...|.| |..|..|. |.||...| | .|           |. ||..|.    .| ...|..|... ... ...||. |  |. |..         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-EMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITT-ATDMWNIGIIA
    .| .. ....||.... |.|...|.| ||||.||||..      ||| |||..|..      . . |||.|.|||.|   . .. . |.| .|.| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YMLLTHTSPFVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLS-------HSWL
| .|.   ||    .... ...               |. | |||. .|.|.|||||||  .|        | |.
YEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DRAK2.AA Ciliate-E2a 32-293 32 3.1e-74 217.92 In-house 1-275 (275) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-275/275
Sequence Identity: 32% (91 aa)

YILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQD-CRAEILHEIAVL-ELAKSCPRVINLHEVYENTSEIILILEYAAGGEIF---SLCLPEL
| .. |..| |.|..|.    | ||...|.| ..|. . |.  ....  ||. . .|  . | .| |.||||. . . |..||  ||| .   . |  . 
YKFI-KKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL--DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFF

AEMVSENDVIRLIKQIL-EGVYYLHQNNIVHLDLKPQNILLS--SIY--PLGDIKIVDFGMSRKIGHACE--LREIMGTPEYLAPEILNYDPI------T
 |   .... ....|.| .|. |.||.||.| ||||.|||.   |    .. ||||.|||....|    .  .  . ||| |.|||.||.  .      .
EE---IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYD

TATDMWNIGIIAYMLLTHTSPFVGEDNQETYLNISQVNVDYSEET-FSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWL
|  ||| .|.| | ||....|| |.. .|.  .. . . |..    .. .|. . |... .|.|.|.||.||. .| | | 
TKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase DRAK2.AA Pkinase 33-293 27 3.5e-74 257.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

ILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILH--EIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGG----EIF----SLC
. . . .|.| |..|..|. |.||...| | .|||..  ... . ..  ||...    ..| .. |....|. ..| ...||. ||    . |       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

LPELAEMV--SENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLS-SIYPLGDIKIVDFGMSRK--IGHACELREIMGTPEYLAPEILN-YDPITTAT
  .    .  ||..... ..|||.|..|.|...|.| ||||.|||..   ..  ..|| ||| ...  . .   .  . |||.|.|||... . ..... 
--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DMWNIGIIAYMLLTHTSPFVGE------DNQETYLNISQVNVDYSEETFSSVS-----------------QLATDFIQSLLVKNPEKRPTAEICLSHSWL
||| .|.| | .|.   || |.      | .. . .| .  ....... .|.|                 . . ||| ..| |.|.|||||| .| | |.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DRAK2.AA Ciliate-E2 33-293 21 4.9e-68 232.34 In-house 1-365 (365) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

ILTSKELGRGKFAVVRQCISKSTGQEY------------------AAKFLKKRRRGQDCRAEILHEIAVLELAKS---------------CPRVINLHEV
.   | .|.| |..|..|  .......                  ..|.  . .  ..   .|. || ..   ..               .| .|...|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YE--NTSEIILILEYAAGGEIFS------LCLPELAE---MVSENDVIRLIKQILE---------------GVYYLHQNN-IVHLDLKPQNILLSSIYPL
..  ... | |..||. ||. |.      .. ..  |     .|. .....||||.               .. |||..| |.| |.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

GDIKIVDFGMSRKIG-------HACELRE--------------------------IMGTPEYLAPEILNYDP---------ITTATDMWNIGIIAYMLLT
  |||.|||.|.|.        | . ...                          | |||.|.||||||. .          ... |.| .|.| |..|.
--IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

HTSPFVGEDNQETYLNISQVNVDYSEE--------------TFSSVSQLATDFIQS----LLVKNPEKRPT-AEICLSHSWL
   ||        . .| | ..|....               . ..|| . |.|.     .|.|.||||.| .| .| | |.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DRAK2.AA CAMK1 131-293 38 6.5e-66 190.56 In-house 106-276 (276) Show / Hide 
Range on Protein: 131-293
Range on HMM: 106-276/276
Sequence Identity: 38% (65 aa)

SENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIK--IVDFGMSRKIGHAC-ELREIMGTPEYLAPEILNY---DPITTATDMWNIGII
.|.|  ...||||. |.|.|...||| ||||.|.|......  .||  | ||| |....| .  .    |||.| |||.|..   .|   | ||| ||.|
TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVI

AYMLLTHTSPFVGED-NQETYLNISQVNVDYSEETFSSVSQL-ATDFIQSLLVKNPEKRPTAEICLSHSWL
 | ||.  .|| .|. ..| .  |.   ... .  . ..|   | |||  .|...|.||.|.| || | |.
TYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase DRAK2.AA CAMKL 32-293 27 2.6e-63 200.86 In-house 1-297 (297) Show / Hide 
Range on Protein: 32-293
Range on HMM: 1-297/297
Sequence Identity: 27% (85 aa)

YILTSKELGRGKFAVVRQCIS-KSTGQEYAAKFLKKRRRGQDCRAE-------------ILHEIAVLELAKSCPR----VINLHEVY-------ENTSEI
|..   .||.| |..|. ..  . ||...| |...|..   |. ..             |  ||. ... .  ..    .| |.||.       |. ..|
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN--IGKHPNIIKLYEVIETPEHDIET-KKI

ILILEYAAGGE--IFSLCLPELAEM--VSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIG-H----ACELREIMG
 |..||. |||   |     .       .|..  |. .||...|.|.|...||| |.|| ||||..      |||.|||.| ..  .       |..  |
YLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPEYLAPEILNY--DPIT-TATDMWNIGIIAYMLLTHTSPFVGEDN------QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICL
.|.| ||||..   .|    ..|.| .|.| |.... . || ....         ||   .    | .  ...||  . |.|...|..|||||||..  .
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

SHSWL
.| |.
NHPWM
Kinase DRAK2.AA CAMK1 32-119 29 9.3e-29 80.67 In-house 1-96 (276) Show / Hide 
Range on Protein: 32-119
Range on HMM: 1-96/276
Sequence Identity: 29% (29 aa)

YILTSKELGRGKFAVVRQCISKST---GQEYAAKFLK-KRRRGQDCR---AEILHEIAVLEL--AKSCPRVINLHEVYENTSEIILILEYAAGGEIF
|... ||.||| |..|..|. |.|   |..|| | .. |.   .. .   . .. ||...      ..| .|...|.|| .... |..|.  |||.|
YEFG-KEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELF
Kinase DRAK2.AA TyrKc 33-293 22 6.9e-14 1.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-293
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

ILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLELA-KSCPRVINLHEVYENT-------SEIILILEYAAGGEIFSLCLP
|   |.||.| | .|.... |   .. | | ||.       |.....|. ..    .. | ...|. |             . ...||...|      | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD-LKDYLR

ELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHA----CELREIM-----GTPE-----YLAPEILNYD
.  . ..  | .    || .|  |||..|..| ||   |.|... .    .|| |||.||.|..      .   ..     |.        .||| .|| 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PITTATDMWNIGIIAYMLLTHTSPFVGE------DNQETYLNISQVNVDYSEET-----FSSVSQLATDFIQSLLVK----NPEKRPTAEICLSHSWL
  ||..| |  |.  . ..|   .   .      .||| . .. | .     .      |      ..| . ..  .    .||.||| . .  |. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DRAK2.AA Pkinase_Tyr 33-186 26 1.7e-09 32.8 Pfam 1-161 (270) Show / Hide 
Range on Protein: 33-186
Range on HMM: 1-161/270
Sequence Identity: 26% (43 aa)

ILTSKELGRGKFAVVRQCISK----STGQEYAAKFLKKRRRGQD-CRAEILHEIAVLELAKSCPRVINLHEVYE-NTSE--IILILEYAAGGEIFSLCLP
|   |.||.| | .|.... |    .|... | | ||     .. ||.. ..|....    ..| ...|. |         |....||...|      | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG-DLLDYLR

EL---AEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKI
.     . ..  | .    || .|  ||...|..| ||   |.|...  ..  .|| |||..| |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NN-VVKICDFGLARDI