Gene DMPK1 (Human)

DMPK1

Species: Human
Alias: DMPK1, DM, DMK, DM1, DMPK, DM1PK
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 19q13.3,

Classification

Group: AGC
Family: DMPK
Subfamily: GEK

Sequence

Name Sequence Type Origin Length Description Download
DMPK1.AA Protein Sugen Kinome 639 None Fasta, JSON
DMPK1.kin_dom Protein Kinase Domain Sugen Kinome 269 None Fasta, JSON
DMPK1.NA RNA Sugen Kinome 3260 None Fasta, JSON

Protein domain

Protein domains of DMPK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DMPK1.AA DMPK 81-349 68 2.9e-289 726.37 In-house 1-270 (270) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-270/270
Sequence Identity: 68% (185 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||||||||||.|.||.||..|||..|||||.||||.|||| |..||.||||..|.|..|||||||.|||||||||.||||..|||||||.|....|||..
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYE
||||||||.|.||.|.|..|||||||||||.||||.|||.|||||||.|...||.|||.||||||||.|||.|||.... |.|.||||||||..||..||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNRDGMVRSKVAVGTPDYISPEVLQAMEDD-GKGRYGPECDWWSVGVCMYE

MFYGQTPFYADSTAETYGKIVHY-KEHLSLPLVDE-GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFF
|.||.|||||||..||||||... |.|||.|  ..  |.|||.|.|..|||..|.||||.|..||. ||||
MLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF
Kinase DMPK1.AA GEK 81-349 72 2.7e-198 665.08 In-house 1-269 (269) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-269/269
Sequence Identity: 72% (197 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||||||||||||.||||||||.|.|||||||.|||.||||.|..||||||||||||||||||.||.||||||||||||.||||||||||||||..|.|..
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYE
|||||.||.||||||||.|.||||||||||.|||..||||||||||||....||.|.| ||||||||.|||||||...|  .|.||||||||.|||..||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGSCLRMNKDGMVQSNVAVGTPDYISPEILQAMEDG--KGRYGPECDWWSLGVCMYE

MFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE--GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFF
|.||.|||||.|..||||||...|.|...|  ..   |.|||.|.|..|.|..|.||||.|..||..||||
MLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF
Kinase DMPK1.AA AGC 81-349 30 1.2e-166 434.98 In-house 1-395 (395) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-395/395
Sequence Identity: 30% (122 aa)

FEILKVIGRGAFSEVAVVKMK------QTGQVYAMKIMNKWD--------MLKRGEVSC-------FREERDVLVNGD----------RRWITQ-LHFAF
||.|||||.|.|..|  |..|      .||..||||...|..        |...  . .       ..|||..|.. .            .|.. ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDENY--LYLVMEY--------YVGGDLLTLLSKFGE----RIPAEMARFYLAE-------IVMAIDSVHR-LGYVHRD-IKPDNILLDRCGHIRLADFG
||...  ||.||||        |.||.. ..|...|     | . |.||||.||       ||.|... |. .|..||| .||.|||||. |||.|.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

SCLKLRADG-------------------------------------------------TVRSLVAVG--TPDYLSPEILQAVGGGPGTGSYGPECDWWA-
.| ... ||                                                 ..|    .|  ||.|..||||           ||..||||. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----------YGKACDWWSF

-LGVFAYEMFYGQTPFYADS----------TAETYGKIV------HYKEHLS-----LPLVDEGVPEEARDFIQRLLC-PPETRLGRG-------GAGDF
 ||.. ||| .|..|||.|.           .|.. ||       . |...       .  |. . .||.|.|..|||  || ||| |       || . 
GLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEI

RTHPFF
. ||.|
KNHPWF
Kinase DMPK1.AA CRIK 81-349 47 1.2e-127 409.17 In-house 1-272 (272) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-272/272
Sequence Identity: 47% (131 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||.  .||.| | .| ||  |||. .||||.| |  .| . .|| | ||||..      |..|| .||||.. |||.|||  ||||| |.. ..     .
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGG-GPGTGSYGPECDWWALGVFAY
|||||||| ..|. |.|  |||||||||.|||.|| ||| ||||||  |.  ...| |.  ||||||  ||.||   |   . |.|| .|||| .|. ||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNRNNHVNSKMPVGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAY

EMFYGQTPFYADSTAETYGKIVH------YKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFF
|| .|.|||  |. ..|| .|         .. || |  |  |  ..|| || ||| .  ||.  .      ||||
EMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFP-DDPKVSPNYRDLIQSLLCNQSKRLKYEQ---LCCHPFF
Kinase DMPK1.AA ROCK 81-349 50 1e-120 407.31 In-house 1-263 (263) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-263/263
Sequence Identity: 50% (137 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
|...|||||||| || .|. |.. .|||||...| .|.|| .   | ||||..      || |||.||||. |||.||.|  ||||  |.|..   .|  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNY--DVPEK

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYE
 |||| .|.|.|.|..| .|..|||.||||.|||. ||..||||| |.|. ..| ||.  |||||||.|||.|.. |   . | || |||||. ||| ||
WARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNKNGMVRCDTAVGTPDYISPEVLKSQG---QDGEYGRECDWWSVGVFIYE

MFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFF
|  |.|||||||   ||.||.  |. |. |  |  . ..|.| |.. |   |.|||| |  | . |.||
MLVGDTPFYADSLVGTYSKIMDHKNSLKFP-DDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQHKFF
Kinase DMPK1.AA S_TKc 81-349 33 3.2e-91 310.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-231/231
Sequence Identity: 33% (95 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVG--GDLLTLLSKFGER--
.|||..||.|||..|  .. | ||...|.||..            .| |...| . .  .| .|. .||| ..||.||||  |  |||.... | | .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGP-ECDWW
   .|  .||||...|. |..  |..| .|||.||.|||||.  || ..|||.. .|           .|||.|..||.|          .||. .||||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL----------GYGKCKCDWW

ALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLC-PPETRLGRGGAGD----FRTHPFF
..|.  |||..|..||.    .... ||.               ..||.|||...|.  || |..   |       . ||.|
SCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DMPK1.AA NDR 81-225 53 9.8e-84 258.04 In-house 1-149 (350) Show / Hide 
Range on Protein: 81-225
Range on HMM: 1-149/350
Sequence Identity: 53% (80 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGD--RRWITQLHFAFQDENYLYLVMEYYVGGDLLT---LLSKFGE
|||.|.||.||| || .|..| ||..||||||.| .|... .|   | |||...  |   .|.. | ..|||..||||||||  |||. |   ||.|.. 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMD-

RIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
  . ..|||| ||.|.||.|||..||.||||||||.|.|. ||| | |||
IFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase DMPK1.AA RSK 84-349 36 5.1e-74 252.22 In-house 1-278 (278) Show / Hide 
Range on Protein: 84-349
Range on HMM: 1-278/278
Sequence Identity: 36% (105 aa)

LKVIGRGAFSEVAVVKMK---QTGQVYAMKIMNKWDMLKRGE-VSCFREERDVLVNGD-RRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGER--
||| |.|.. .| ... .   .|||.||||. .|  . .|   .   ..||..|        | .|| |||.| .|||.|||  ||.|.| |.| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDR---CGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ-AV-GGGPGTGSYGPECDW
.  . |.||.||||.|..  | .| .|||.||.|||.|     |||.| ||| | ..|.| . .    ..| .|. ||.|  |  .||     ..  |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGG-----HDKACDW

WALGVFAYEMFYGQTPFYA---DSTAETYGKIVHYKEHLSLPLV-DEGVPEEARDFIQRLLC-PPETRLG--RGGAGDFRTHPFF
| |||  |||. |..||..   .. .|.  .| . |  .||..  .. . .||.|.|...|.  |. |||  ...| . . ||.|
WSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase DMPK1.AA AGC-Unique 81-349 30 8.9e-68 231.49 In-house 1-270 (270) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-270/270
Sequence Identity: 30% (85 aa)

FEILKVIGRGAFSEVAVVKMK---QTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERI
|||||.|| |.. .|..|  |    |...||||.||| ||.|. ..     |. .|   .   . ..|..|| . .| ..|.|  |||... . .  | .
FEILKHIGVGSYGRVYAVRRKNGCDTEKFYAMKVMNKRDMSKHKQMVHHNTEWMILTTMHHPFFMRMHYSFQNKDHLFMCMDYVPGGDMFHHMQN-AECF

PAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG-SCLKLRADGTVRS-------LVAVGTPDYLSPEILQAVGGGPGTGSYGPEC
. | |.||..|..  |   |    .|||||| |||.|  |||.. |.| |     .   ..           .||..|. |||    .       .|  |
IEESAHFYICEVICSIHYLHENHIIHRDIKPENILIDNDGHIMITDYGLSKTGCDSVDAIQNGGEGGFATTFCGTRHYMAPEIHTEKK-------HGKSC

DWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCP-PETRLG--RGGAGDFRTHPFF
|||. |.  ..|  .. || |    . |   .  .  . .| .      ...||. .|. . |  |||    |  . . |..|
DWWSVGITYCDMRTDRSPFDASNRNDMYDSMI--QKRPRMPMF---LSPDEQDFVNKLIVRDPNQRLGNSPQGFEEIKSHDMF
Kinase DMPK1.AA MAST 81-225 40 3.9e-60 182.12 In-house 1-147 (337) Show / Hide 
Range on Protein: 81-225
Range on HMM: 1-147/337
Sequence Identity: 40% (60 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQD--ENYLYLVMEYYVGGDLLTLLSKFGERIP
||..|.|..||.  |  || | |.. .|||..|. |....  |   . ||..|.. .  ..  .  .||   ..||..||||  |||  .||. .| . |
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

AEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
 .||..|.||.| ...  |  | ||||.||||.|.|  ||| |.|||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase DMPK1.AA MAST 81-225 42 5.2e-59 188.72 In-house 1-144 (334) Show / Hide 
Range on Protein: 81-225
Range on HMM: 1-144/334
Sequence Identity: 42% (61 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE
||. |.|..||.  |  || | |.. .|||...| ||...  |.  . ||..| . .  ..  .  .|| .|||..|||| .|||. .||. .| . . .
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYG-YFDEW

MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFG
||..|.||.|....  |. | ||||.||||.|.|  ||| |.|||
MAKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase DMPK1.AA Pkinase 81-349 27 1.1e-57 202.77 Pfam 1-293 (293) Show / Hide 
Range on Protein: 81-349
Range on HMM: 1-293/293
Sequence Identity: 27% (84 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFR-EERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGG----DLLTLLS-KFG
..|...||.|.|..|   . | ||...|.||..| .  .  ... .|  |  .. . .   | .|. .|.|....|.||||  ||    || ...| . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ERI--PAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHI----RLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPE
 ..  . . ..||. .|. ...  |. | .|||.||.|||.|. |||    ...|||.. ...    .   . .|||.|..||...      |   |||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR------GGQYYGPK

CDWWALGVFAYEMFYGQTPFYAD------STAETYGKIVHYKEHLSLPLVDE----------------GVPEEARDFIQRLLCP-PETRLGRGGAGDFRT
.|.|..|.  |||. |..||. .      .  . . .| . . | . |  ..                 ..||..||| ..||. |. |..   | .   
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQ

HPFF
||.|
HPWF
Kinase DMPK1.AA NDR 241-349 39 1.6e-41 125.44 In-house 241-350 (350) Show / Hide 
Range on Protein: 241-349
Range on HMM: 241-350/350
Sequence Identity: 39% (46 aa)

AVGTPDYLSPEILQA-VGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEG----VPEEARDFIQRLLC-PPETR
.||||||. ||..|   |       |...|||| ||.  |||  |..||..|.. ||. || ..|. .  |... .    . .|| | |.||.|  |..|
TVGTPDYMAPEVFQQKTG-------YNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHR

LGRGG--AGDFRTHPFF
||..|  . ... ||||
LGSHGKGVDEIKSHPFF
Kinase DMPK1.AA MAST 242-349 36 7.9e-37 109.57 In-house 229-337 (337) Show / Hide 
Range on Protein: 242-349
Range on HMM: 229-337/337
Sequence Identity: 36% (42 aa)

VGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAE-TYGKIVHYKEHLSLPLV-----DEGVPEEARDFIQRLLCP-PETR
.|||||..||..       |.|.||.  |||..|.  ||   | .|| .|.  | . ..|........ | .     |. ...||.| |..|| | | .|
CGTPDYIAPEVIL------GQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKR

LGRGGAGDFRTHPFF
|| .|| .  .||||
LGANGADEIKQHPFF
Kinase DMPK1.AA MAST 242-349 36 2.9e-33 104.36 In-house 225-334 (334) Show / Hide 
Range on Protein: 242-349
Range on HMM: 225-334/334
Sequence Identity: 36% (42 aa)

VGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYK-EHLSLPLV-----DEGVPEEARDFIQRLLCP-PETR
.|||||..||..       |.|..|.  |||..|.  || . | .||  |.. |....|....    ..| .     ||  ..||.| |..|| | |..|
CGTPDYIAPEVIL------GQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKR

LGRG-GAGDFRTHPFF
|| . || .  .||||
LGANNGADEVKQHPFF
Kinase DMPK1.AA S_TK_X 350-417 24 6.7e-14 53.43 SMART 1-79 (79) Show / Hide 
Range on Protein: 350-417
Range on HMM: 1-79/79
Sequence Identity: 24% (21 aa)

FGLDWDGLR----DSVPPFTPDFE----GATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLP----------FVGYSYSC
 |.|||.|.       |||.|.      ..|||.|||  ..  |.|       |... ...  ... .          | |..|..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase DMPK1.AA TyrKc 81-350 19 3.3e-11 -41.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 81-350
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

FEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNG---DRRWITQLHFAFQDE------NYLYLVMEYYVGGDLLTLLS
 . .|..|.||| ||   ..|   .  | | ...        .  |..|  .. .        .  .  . |..        |..||||  .|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRAD-------GTVRSLVAVGTPD-----YLSPEILQAVGGG
| ..... .    .   |    .  |. ...|||.   |.|... .... .||| . ..  |        . |.    |. .      ..|| .      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI------

PGTGSYGPECDWWALGVFAYEMF-YGQTPFYA-----DSTAETYGKIVHYKEHLSLPLVDEG-------VPEEARDFIQRLLCP-PETRLGRGGAGDFRT
  .| . .. | |. ||  .|.| |||.| .       | .| . .. . .    .|  ...        |.|  . ...     || |        |..
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY---RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP------TFSE

HPFFF
   .|
IHECF
Kinase DMPK1.AA Pkinase_C 367-419 22 5.8e-07 27.81 Pfam 1-46 (46) Show / Hide 
Range on Protein: 367-419
Range on HMM: 1-46/46
Sequence Identity: 22% (12 aa)

DFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMA
  ...|||.|||  ..  ..| .       . ..  . | ..||.|..|.   
QVKSPTDTSNFDPEFTDEPPMDTP------PDWR-MSSGDQEPFRGFTYVNPD
DMPK_coil DMPK1.AA DMPK_coil 480-540 42 7.9e-26 91.09 Pfam 1-61 (61) Show / Hide 
Range on Protein: 480-540
Range on HMM: 1-61/61
Sequence Identity: 42% (26 aa)

ELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAE
|||.|||.|....||...| ..... |..| ..|.|||..||.||....||...|| |.|.
ELQSALEAEIRAKQSIHEELNKVKAANIQFECKLQEAEKKNRELEQEMEQLKKEMEMLRAR