Gene CK1e (Human)

CK1e

Species: Human
Alias: MGC10398, CSNK1E, CK1e, HCKIE
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 22q13.1,

Classification

Group: CK1
Family: CK1
Subfamily: CK1-D

Sequence

Name Sequence Type Origin Length Description Download
CK1e.NA RNA Sugen Kinome 2820 None Fasta, JSON
CK1e.AA Protein Sugen Kinome 416 None Fasta, JSON
CK1e.kin_dom Protein Kinase Domain Sugen Kinome 261 None Fasta, JSON

Protein domain

Protein domains of CK1e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CK1e.AA CK1 9-267 74 7.6e-216 723.35 In-house 1-271 (271) Show / Hide 
Range on Protein: 9-267
Range on HMM: 1-271/271
Sequence Identity: 74% (203 aa)

YRLGRKIGSGSFGDIYLGANIASGEE--VAIKLECVKTKHPQLHIESKFYKMMQG------GVGIPSIKWCGAE--GDYNVMVMELLGPSLEDLFNFCSR
||.|||||.||||||||| |. .|||  ||||||. |.||||||.|.|.||..||      ..||| ..||| |  ||||.|||.|||||||||||||.|
YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR

KFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL-GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLE
||||||||..|||||.||||.|.|||||||.||||||||. ||... ||||||||||.|||..|||||||||||||||||||||||||||||||||||.|
KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME

SLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKG-YPSEFSTYLNFCRSLRFDDKPDYS
|||||||||. ||||||||||.||.||||.|.|||||||.|.|||| .|.|| .|||.||.|.|..|||| 
SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase CK1e.AA CK1-D 9-269 86 2.3e-211 708.5 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 86% (226 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLL
||.|||||||||||||.|.||...|||||||||.||||||||||||||||||||.|||.|.|||.|||||||||.|||||||||||.|.|||||||||.|
YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML

ADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNL
|||||.||||||..||||||.|||||||||||.||.||||||||||.||||||||||||||||||||||||||||||.|||||||||||||||||||||.
ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR

GSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYL
||||||||||||||||||||.||||||.|..|||||||||..|.|.||.|.|||||||.||
GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase CK1e.AA CK1-Unclassified 9-241 68 7.29999999999e-200 595.5 In-house 1-244 (244) Show / Hide 
Range on Protein: 9-241
Range on HMM: 1-244/244
Sequence Identity: 68% (167 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGV-------GIPSIKWCGAE--GDYNVMVMELLGPSLEDLFNFCSRK
||...|||.||||.||.. |. ..||||||||  ..||||| .| |... .|.|        ||| . ||| |  ||||.|||.|||||||||||.| ||
YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK

FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDA-RTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLE
|||||||..|||||.||||.|.||||||| |||||||| |||. . ||||||||.|.|.|. .|..||||||||||||||||||||.|||||||||||||
FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE

SLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLC
||||||.||  ||||||..|| .| .|||.| |.|||||.| ||
SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC
Kinase CK1e.AA CK1-A 9-269 74 1.5e-180 606.14 In-house 1-261 (261) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-261/261
Sequence Identity: 74% (195 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLL
||| |||||||||||||| || .|||||||.|  | .||||  |.| |...||.|||| ..| | | |||||||.|||||||||||||.|.|..||||.|
YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML

ADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNL
|||||.||||.| |||||||.||||||||.|.  | ...|||||||||||.||.||||||| ||||||||||||| |||||||||||.||.|||.||||.
ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR

GSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYL
|.|||||.||.||.||||.|||||||||||.||||.|.||. |.|.||.|||...||| ||
GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase CK1e.AA CK1-G 9-269 57 2.2e-156 525.83 In-house 1-266 (266) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-266/266
Sequence Identity: 57% (152 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGV-GIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLL
|| |.||| |.|| ...| |.  .| ||||.| .|.. |||| | .|||.. | . ||| . . | .| ||.|||.||||||||||..| ||||.|||..
YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM

LADQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMY
.| |||.|.||.||.. | ||||||||| |    |. ....|||||.||.|.| .| ||||||| | ||||||| ||||||| |||||||.|.|| . ||
VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY

FNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKG--YPSEFSTYLNFCRSLRFDDKPDYSYL
|  |||||||||| . ...|..| ..| .|.||.||..  .| .| ||| . |.| |...||| ||
FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase CK1e.AA CK1 9-269 40 3.4e-144 485.32 In-house 1-339 (339) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-339/339
Sequence Identity: 40% (138 aa)

YRLGRKIGSGSFG-DIYLG-----ANIASG-----EEVAIKLECVKTK--HPQLHIESKFYKMMQGG-------------------VGIPSIKWCGAEGD
.....|||.|.|| .||..      .. ..     ||.|.|.| .|..  ||||..|...||..|||                   ...| . |.. |.|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

--YNVMVMELLGPSLEDLFN---FCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL------GKKGN--------LVYIIDFGLAK-KY
  ||.|||.||||.||||..   .| ||||.||.| .|.||....||.|...|||||.|||||.||.      ||. .         ||.||||.|. ||
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY

RDA-----------RTHQHIPYRE---NKNLTG-TARYASINTHLGIEQSRRDDLESLGYVLMYFNLGS--LPWQGLKAATK-------RQKYERISEKK
||            .|.||.|.||   .|...| ||||.|||.|||.||.|||||.|..|.|.... |.  ||||..|. .|       ..||| |.|||
RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK

MSTPIEVLCKG-----YPSEFSTYLNFCRSLRFDDKPDYSYL
||||.. ||..     .|.|| .... .|||...|.||| ..
MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase CK1e.AA TTBK 9-269 38 6.6e-60 205.33 In-house 1-257 (257) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-257/257
Sequence Identity: 38% (101 aa)

YRLGRKIGSGSFGDIYLGANIASG-EEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVL
 .  .||| | || || . ..    |.||||.| ....   | .|    | .||   .     || . ..| |||.|.| .| ||    .| .||| | |
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

LLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMY
 |  |..  || |||  | |||.|| || || . .. . .|..||||| .|  |      | ||     ||.|||||| |.  |  |.||| || |.|  
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVE

FNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYL
|  | |||  .|        . . | |      .| |  |.||.....  .|| . |.|||  .
FVQGQLPWRKIKDK------DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase CK1e.AA TTBKL 9-273 29 1.5e-59 199.75 In-house 1-288 (288) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-288/288
Sequence Identity: 29% (87 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKT-KHPQ--LHIESKFYKMMQ--GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRK--FS
..  ..||.| || .|.. .. . ...|.. | ...  .    ...| .  . .|  |   .| ....| ..||| |||.|.||.| || .   .|  ||
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKK----GNLVYIIDFGLAKKYRDARTHQ----------HIPYRE---NKNLTGTARYASINT
  |.. .. | .  . ..|.. |||||||| |. .|. ..      .||.||||.|..|..    .          . . |.      . || ||.|.| 
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKG------YPSEFSTYLNFCRSLRFDDKPDYSYLRQLF
|.. ||.| ||| |. |.......| |||.... .      ..| ..|...  |.|.|.       ||||       ||||. | |||......|
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase CK1e.AA Worm6 9-269 28 1e-54 188.06 In-house 1-279 (279) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-279/279
Sequence Identity: 28% (79 aa)

YRLGRKIGSGSFGDIYLGANIASGE--EVAIKLEC--VKTKHPQLHIESKFYKMM--QGGVGIPSIKWCGAEGD--YNVMVMELLGPSLEDLFNFC-SRK
. ...|||.|.||..|.  .   ..  ..|.|.|    . |...| .|    |    ... . ..|  .|  .   .| .||.|.|..|.||  ..  ||
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL-----GKKGNLVYIIDFGLAK-KYRDARTHQHIPYR-ENKNLTGTARYASINTHLGIEQSR
||. | | .| |.. .||  |.  |||||||| ||  |       ..   .|..|||... |. . .  . .. | ..    || |||... | |.||.|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

RDDLESLGYVLMYFNLGSLPWQGLKAATKRQ-KYERISEKKMSTPIEVLCKGYPS-EFSTYLNFCRSLRFDDKPDYSYL
.||.||  |..  . .| |||...|.    .  ....  .. ..  . . .. |  ||.  .    .... |.||| ..
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase CK1e.AA Pkinase 9-260 23 1.3e-46 165.94 Pfam 1-258 (293) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-258/293
Sequence Identity: 23% (64 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHI------ESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFC------
|..||||||||||  |.. .. .|..||.|  ........ ..      | .  |...    .  . |.   .|.  ||||...  |. ..  .      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VMDLFDYISTW

-SRKF--SLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNL---VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHL-GIE
 ...|  | ...   . |... .||.||...||||.||.|.|.   ..|..   | |.||||||...      . ... .. ..|| .|..   .. | .
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQY

QSRRDDLESLGYVLMYFNLGSLPWQGL----KAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRF
 ... |  |.| .| .. .| .|..|     . ....|...|| ... . ... .| .....  ..   .. ...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-HF-HWT
Kinase CK1e.AA VRK 80-213 38 2.4e-27 84.96 In-house 106-240 (284) Show / Hide 
Range on Protein: 80-213
Range on HMM: 106-240/284
Sequence Identity: 38% (53 aa)

MVMELLGPSLEDLFN-FCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLT--GT
|||. .| .|. .    .  .|| |||| || .|.   ||.|...  | |.|  | | |. |  . || .|.||| .| .     | .| |..     ||
MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKNPDQVYLVDYGLAYRYCPN--GKHRQYKEDPRRCHNGT

ARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW
  . |.  |.|   ||| |||.||| .|.   |.|||
CEFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPW
Kinase CK1e.AA S_TKc 9-287 18 1.1e-15 52.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-287
Range on HMM: 1-231/231
Sequence Identity: 18% (57 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRK--------F
|...||||.|.||  |.. .. .|..||||         ..  | .  |.  .   |  .. .  . |.  ||||... .| ||| .  ..        |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR-RDDLESL
.  ..  .. |... .||.||...||||.||.| |.        . |.|||||...              . . ||  | .         .. . |  |.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHR--------QGFS-------Y
| .|  .  |  |..     .  . ...|                                      . .... |.....        . .         
GCILYEMLCGYPPFP-----QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCH

DYV
 ..
PWF
Kinase CK1e.AA TyrKc 9-273 20 3e-08 -89.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGG---VGIPSIKWCGAEG-------DYNVMVMELLGP-SLEDLFNFCS
 .||.|.|.| || .|.|  .   ..||.|     .   .  . .    |.. |     |  .  .  ..       .   .|||.    .| |    . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

RKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDA----RTHQHIPYRENKNLT--GTARYASINTHLGIEQS
.|...|. |  . |  .  ||.||||.||||    | | | ..    | | ||||...  |       .. .  .| |.       |  ..         
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP---------

RRDDLESL-GY------------VLMY--FNLGSLPWQGLKA--ATKRQKYERISEKKMSTPIEVLCKG-----YPSEFSTYLNFCRSLRFDDKPDYSYL
     |..  .            |.|.  | .|  |. |      . .. .|.. . ..  . .  .        |.|  .    |     .| |  | .
-----ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

RQLF
...|
HECF
Kinase CK1e.AA VRK 9-25 64 9e-06 14.87 In-house 1-17 (284) Show / Hide 
Range on Protein: 9-25
Range on HMM: 1-17/284
Sequence Identity: 64% (11 aa)

YRLGRKIGSGSFGDIYL
.|||..||.| || |||
WRLGKPIGQGGFGCIYL
Kinase CK1e.AA Pkinase_Tyr 9-38 32 0.000462 14.38 Pfam 1-34 (270) Show / Hide 
Range on Protein: 9-38
Range on HMM: 1-34/270
Sequence Identity: 32% (11 aa)

YRLGRKIGSGSFGDIYLGANI----ASGEEVAIK
 ..|.|.|.|.||..|.|         . .||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVK
Kinase CK1e.AA Pkinase_Tyr 117-129 69 0.032805 8.11 Pfam 125-137 (270) Show / Hide 
Range on Protein: 117-129
Range on HMM: 125-137/270
Sequence Identity: 69% (9 aa)

EYIHSKNFIHRDV
|| .|||.||||.
EYLESKNCIHRDL