Gene CaMKK1 (Human)

CaMKK1

Species: Human
Alias: MGC34095, CaMKK1, DKFZp761M0423, CAMKK1, CAMKKA
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 17p13.2,

Classification

Group: Other
Family: CAMKK
Subfamily: CAMKK-Meta

Sequence

Name Sequence Type Origin Length Description Download
CaMKK1.AA Protein Sugen Kinome 505 None Fasta, JSON
CaMKK1.kin_dom Protein Kinase Domain Sugen Kinome 282 None Fasta, JSON
CaMKK1.NA RNA Sugen Kinome 3529 None Fasta, JSON

Protein domain

Protein domains of CaMKK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMKK1.AA Meta 128-409 71 1.1e-271 794.22 In-house 1-287 (287) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-287/287
Sequence Identity: 71% (205 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLY
|.|..|||||.||||.|||||....|||||.||||||||||||.|||||||....|||......||.||||||||||||||.|||||.||||||.||.||
YRLMEEIGKGSYGVVKLAYNEEDHHHYAMKILSKKKLLKQYGFMRRPPPRGNKPNQGGCIQPRNPLDRVYQEIAILKKLDHPNVVKLVEVLDDPNEDYLY

LVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSS--TAGTPAFMAPEAISDS
.||....||||||||||.|.||.||..|.||...||||||.|||.|||||||||||.||||||||||||||.|||.||.|..  ||||||||||||.|..
MVFEYVEKGPVMEVPCDNPLSEDQAWSYFRDIVCGLEYLHYQKIIHRDIKPSNLLLNDDGHVKIADFGVSNEFEGDDAFLCNGSTAGTPAFMAPEACSEE

GQS-FSGKALDVWATGVTLYCFVYGKCPFID--DFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV
... ..|.||||||.||||||||.|.|||||  ..|..||.||||.||.|||.|||||.|||.|..|||||||.||..|.||.||||
QNHFYCGRALDVWAMGVTLYCFVFGQCPFIDKTNYIMCLHDKIKNHPVMFPEQPEISEDLKDCIKRMLDKNPEHRIMIPEIKTHPWV
Kinase CaMKK1.AA CAMKK 128-409 41 3.3e-193 619.11 In-house 1-396 (396) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-396/396
Sequence Identity: 41% (163 aa)

YKLQSEIGKGAYGVVRLAYNESE-DRHYAMKVLSK----KKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPA
|.|..|||.|..|.|.||||| . ..|||.|...|    |||.|...|.|.||.|.....|.|....  |...|||||||.||..|.|.|||.||.||| 
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

EDNLYLV-FDLLRKGPVMEVPCDKP--------------------------FSEEQ---------------------ARLYLRDVILGLEYLH-CQK---
.|..|.| .... .|..|..|..|.                          .||.|                     |. |.||.|.|||||| .||   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------IVHRDIKPSNLLLGDDG---HVKIADFGVSNQFEGNDAQLSS-----------TAGTPAFMAPEAISD-SGQS-----------
                |.||||||.|.|....|   ||||||||||..|||.|..||.           |||||||||||..|.  ...           
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-FSGKALDVWATGVTLYCFVYGKCPFIDDFILALHR---KIKNEPVVFPE-----------EPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV
 ..|||.|.||.||||||||.|||||.......||.   ||||.|..|||           .|||||.|||||..||.|||..|| .|.|| ||||
IYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase CaMKK1.AA S_TKc 128-409 28 1.5e-96 327.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLY
|..  .|||||.|.|..... . .|..|.|...                                 |....||.|||| .| |.|||..| .|   |.||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLY

LVFDLLRK--GPVMEVPCDKP-------FSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMA
.|....    | .... ....       |.| .|| |.. ....|||.| ..|.|||.||.|.|| .  |.||.|||.. |.       ..  ||| .||
MVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMA

PEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKL-------HPWV
|| .     ...... |.|. |..|| ...|. ||    . .. .||.            |.|.||.| |.|.|.|| |... ..         |||.
PEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMKK1.AA AGC 128-409 23 2.3e-95 246.37 In-house 1-395 (395) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-395/395
Sequence Identity: 23% (102 aa)

YKLQSEIGKGAYGVVRLAYNE------SEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLL----PLERVYQE------------IAILKK
...   ||||..| |.|.         . .. ||||||.||.                        | ..     .|... |              ||.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKH------------------------KIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEK

LD----------HVNVVK-LIEVLDDPAEDNLYLVFDLLR---------KG-PVMEVPCD--K--PFSEEQARLYLRD-------VILGLEYLHC-QKIV
..          | ..|| |     |.  ..||.| ...           |   .   ..  |   |.||.|| |.         ..|.|||||  ..|.
CNHTHNHPIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGII

HRD-IKPSNLLLGDDGHVKIADFGVSNQFEGND--------------------------------------------------AQLSSTAG--TPAFMAP
||| .|| |.|| .|||.|..||| . .. ...                                                  .. ..  |  || .|||
HRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAP

EAISDSGQSFSGKALDVWA--TGVTLYCFVYGKCPFIDD----------FILALHRKIK------NEPVVFP--------EEPEISEELKDLILKMLDKN
| .        ||| | |.   |. .| ...|. || .|              .. ||.      |..| ||        |....|.|.|||| |.| |.
EIL-------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKD

PETRIG----------VPDIKLHPWV
|| |.|          . .|| ||| 
PEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CaMKK1.AA CAMKL 128-409 31 1.3e-90 289.35 In-house 1-297 (297) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-297/297
Sequence Identity: 31% (97 aa)

YKLQSEIGKGAYGVVRLAYNESE-DRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLD---HVNVVKLIEVLDDPAE
|..  ..|||..|.|.|| ...   ...|.|.. |||. .     .....           |..  . |...||.|.|.|.   | |..|| ||...|  
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG----------QKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEH

----DNLYLVFDLLRKGP------VMEVPCDK-PFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDG--HVKIADFGVSNQFE-G---NDAQ
    . .|||  .   |       . . .. . ...|..|| | | .. ...|.| ..|||||||| |.|| ..|   .||.||| ||... .   ..  
DIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQK

LSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDD--------FILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRI
|.   |.|..|||| ...  ... |.. |.|. ||.||  |.|. || ||         |  |..||.     .|  ...| ...||| ||| .||| |.
LKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP

GVPDIKLHPWV
 . .|. |||.
TIHQIMNHPWM
Kinase CaMKK1.AA CAMK 133-409 22 3.3e-85 274.4 In-house 1-425 (425) Show / Hide 
Range on Protein: 133-409
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

EIGKGAYGVVRLAYNESED------------RHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAK----------------QLLPLERVYQEIAILK
..|.|..|.|.|... .              ...|.|...|||| ..       .                             .   ...|..||.|.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQN-QDY-S------------NCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMK

K-------LDHVNVVKLIEVLDDPA-----------------EDNLYLVF---DLLRKG----P----VMEVPC------------DKPFSEEQARLYLR
|       ||| |..||.|| .||                  ....|.|.   ..   |         . | .|            .. |.|..|| | |
KLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFR

DVILGLEYLHCQKIVHRDIKPSNLLLGDD-----------------GHVKIADFGVSNQFEGN-----------------------DAQLSSTAGTPAFM
 .. ...|.| ..|||||.|| |.|| |.                 . .||.||| .|.|...                       .  ..   |||..|
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PEAISDSG-----------QSFSGKALDVWATGVTLYCFVYGKCPFIDDF-------------ILALHRKIKNEPVVFPEEP----------------
| || .. .|           .   |.. |.|. || ||  . |. || .|              .  |..||..    ||...                
AAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDI

------EISEELKDLILKMLDKNPETRIGVPDIKLHPWV
      ..|.| |||| ||| ..|| |. . ... |||.
SDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMKK1.AA Pkinase 128-409 26 1.4e-81 282.15 Pfam 1-293 (293) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-293/293
Sequence Identity: 26% (86 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLK--QYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDN
|.. . ||.|..|.|..... .. . .|.|...|..  .  ..   |.                        .||.|.|.|.| |.|.|...  |  .|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL------------------------SEIQIMKRLNHPNIVRLYDWFED--KDH

LYLVFDLLRKG----PVMEVPC---DKPF--SEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHV----KIADFGVSNQF-EGNDAQLSSTA
.|.|......|      ...     ...|  ||.... |.. .. ||||.| ..|.|||.||.|.|. ..||.    ||.|||.. || . |.  ... .
IYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC

GTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDD------FILALHRKIKNEPVVFPEEPEIS-------------------EELKDLI
||| .|||| |   |..  |.. |.|. |..||... |. || ..        ......|.  |. |... ..|                   ||.||.|
GTPWYMAPEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

LKMLDKNPETRIGVPDIKLHPWV
 ..|.|.|. |.. ..|. |||.
KWCLCKDPKKRPTAEQILQHPWF
Kinase CaMKK1.AA CAMKK-Unclassified 248-409 30 1.2e-70 229.36 In-house 176-392 (392) Show / Hide 
Range on Protein: 248-409
Range on HMM: 176-392/392
Sequence Identity: 30% (67 aa)

SEEQARLYLRDVILGLEYLHCQK---------------------IVHRDIKPSNLLLGDDGH-----VKIADFGVSNQFEGNDAQ-LSSTAGTPAFMAPE
.|.... | |....|| |.| ..                     |.|||||| |.|.....      .||||||.|  .|. .   |...|||..|||||
HEQYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPE

AISDSGQSFSGKA-------------------------LDVWATGVTLYCFVYGKCPFIDDFILALHR-KIKNEPVVFPE--EPEISEELKDLILKMLDK
..|....   ...                          |.|..|||.||.||.. ||  .    |   .|..  ..||   .|..|.|.|||| ||.||
FWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFKDLIQKMCDK

NPETRIGVPDIKLHPWV
||..|| . ..  |||.
NPKKRITIDQMLVHPWF
Kinase CaMKK1.AA Ciliate-E2-Unclassified 128-409 24 3.9e-69 235.98 In-house 1-352 (352) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-352/352
Sequence Identity: 24% (94 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLK--------------------------QYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIA
||..  ||.|..|.|.........  |||| ..|..  |                                                     ..  |.  
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRK-------------------------YNKIMQQ--

ILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCD------------------KPFSEEQAR-----LYLRDVILGLEYLHCQK-IVHRDIK
||. ..| ..||....  |  ..|.|.| .... |  ..  ..                  | |.|.||.      |.. ...|||||| .. |.|||||
ILLNHPHPFIVKMFYCFQD--KQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIK

PSNLLLGDDG---HVKIADFGVSN---QFEGNDAQ-------------LSSTAGTPAFM----APEAISDSGQS---FSGKALDVWATGVTLYCFVYGKC
|.|.|. ..|   ..||.||| |    |....|               .....||| .|    ||| .   ...   .  .. |.|. || ||....|..
PENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGYY

PFID-DFIL---------------ALHRKIKNEPVVFPEEPE------ISEELKDLIL----KMLDKNPETRIGVPDIKLHPWV
|| | . .                 |...||. .. ||..|.      .|.| ||.|     |||.|||. ||. ..|. ||| 
PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CaMKK1.AA Ciliate-E2 128-409 22 7.1e-67 228.48 In-house 1-365 (365) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERV--------YQEIAILK---------------
||..  ||.|..|.|... . .... .|.|.   .|. ..               | . ....  ....         ||| |..               
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQ------------MQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNIL

-KLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDK------------PFSEEQARLYLRDVIL---------------GLEYLHCQK-IVHRD
 .|.| |..|..|.  .  ..|.|||....  |  ..   ..            .|.|.... . . ..                .||||| .. |.|||
EQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRD

IKPSNLLLGDDGHVKIADFGVS-----------------NQFEGN---------------DAQLSSTAGTPAFMAPEAISDSG------QSFSGKALDVW
|||.|.|.     .||.||| |                 .  . .               . .  ...||| .|||| ..  .      |   ... |.|
IKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIW

ATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEE----------------PEISEELKDLILK----MLDKNPETRIG-VPDIKLHPWV
. ||.||....|| ||         ..||. .. ||..                 ..|.| |||| |    ||.|.|| ||.   .|. ||| 
SLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CaMKK1.AA ULK 128-409 26 9e-64 218.18 In-house 1-329 (329) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-329/329
Sequence Identity: 26% (90 aa)

YKLQSEIGKGAYGVVRLAYNESE----DRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLD--------HVNVVKLI
| |  ..|||..|.|  ..|.      .  .| |...|.|. ...                |  .... |  . .|| |.|||.        | |.|||.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQE------------G--QYMWQL--LKNEIKIMKKLKSPNRHKNHHPNIVKLY

EVLDDPAEDNLYLVFDLLRKG----------PVMEVPCD--KPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDD------------GHVKI
... .. ..|.|.....   |          . .|      | .||..|. .... . |. .|| ..|.||||||.| |. ..            |..||
DWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDT-EEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKI

ADFGVSNQFEGN---DAQLSSTA------GTPAFMAPEAISDS--GQSFSGKALDVWATGVTLYCFVYGKCP----FIDDF---ILALHRK-------IK
|||| . ... .   .... ..       ||| .|||. ...   .. .. .  |.|  |. .|  .|||.|    | |..   |  | ..       ||
ADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIK

NEPVVFP---EEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV
..|  ||   ..| ||.|.|||| .|| .... ||  ...  |||.
KQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CaMKK1.AA ULK 128-409 27 1.1e-63 217.87 In-house 1-324 (324) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-324/324
Sequence Identity: 27% (95 aa)

YKLQSEIGKGAYG-VVRLAYNESE---DRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLD---HVN--VVKLIEVL
| |  ..|||..| .|  ..|.     . ..| |. .|||. |..                |   | . ..   .|| |.|||.   |.|  .|||....
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQE------------G---QYM-WQLLKNEIQIMKKLKELKHPNHHIVKLYDWF

DDPAEDNLYLVFDLLRKG----------PVMEVPCD--KPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDD------------GHVKIADF
 .. ..|.|.....   |          . .|      | .||..|. .... . |. .|| ..|.||||||.|.|. ..            |..|||||
ETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE-T-EEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADF

GVSNQFEGND---AQLSSTA------GTPAFMAPEAISDS--GQSFSGKALDVWATGVTLYCFVYGKCP----FIDDF--ILALHRK-------IKNEPV
| . ... |.    .. ..       ||| .|||. ...   .. .. .  |.|  |. .|  .|||.|    | |..  |  | ..       |||.|.
GFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPI

VFP---EEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWV
 ||   ..| ||.|.|||| .|| .... ||  ..|  |||.
QFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase CaMKK1.AA CAMKK-Unclassified 128-240 33 2e-22 69.58 In-house 1-111 (392) Show / Hide 
Range on Protein: 128-240
Range on HMM: 1-111/392
Sequence Identity: 33% (40 aa)

YKLQSEIGKGAYGVVRLAYNESED-----RHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPA
| . ...| |..| |.|| .. ..      ..| || .|| .||.  |        .. . ..  |    |  |.||||| |||.|.|..|| || ||| 
YEFLDKLGRGSFGKVKLATRRYTTDDGVQKQFAIKV-FKKQKLKKKKF--------IYNDNAFTMKMKNRLHLVQQEIAIMKKLWHPNICKLYEVIDDPD

EDNLYL--VFDLLRKGPVME
.| .|.  | ... .| .|.
NDKIYMGQVMEYCQMGQIMS
Kinase CaMKK1.AA TyrKc 128-409 20 7e-15 17.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 128-409
Range on HMM: 1-280/280
Sequence Identity: 20% (64 aa)

YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPAKQLLPLERVYQEIAILKKL--DHVNVVKLIEVLDDPAE--
 .|  ..| ||.|.|...      .  | |.| . .                             .|  ..|. |..||  .| |.|.|. |  .. .  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNF

---DNLYLVFDLLRKGPVMEVPCDKP--FSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGN------DAQLSSTA-
   . |..|. .  .|   .   ..   .. ..   .  ..  | |||| ....|||.   | |.|....|||.||| |   .        .   ...  
MYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEH

-GTP-----AFMAPEAISDSGQSFSGKALDVWATGVTLY-CFVYGKCPFID-----DFILALHRKIKNEPVVFPEEP-------EISEELKDLILKMLDK
 |.        ||||.|      |. |  |||. ||...  | ||. |  .          .....|.     . .        . ..|. .....  . 
KGGKTMLPIRWMAPECI--NYGKFTTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

NPETRIGVPDIKLHPWV
.|| |    .|  |   
DPEDRPTFSEI--HECF
Kinase CaMKK1.AA Pkinase_Tyr 262-344 32 1.6e-07 26.12 Pfam 123-205 (270) Show / Hide 
Range on Protein: 262-344
Range on HMM: 123-205/270
Sequence Identity: 32% (29 aa)

GLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGT-----PAFMAPEAISDSGQSFSGKALDVWATGVTLY
|.|||. ....|||.   | |......|||.||| .     || .  .....        ||||.|...   |. |  |||. ||...
GMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGK--FTTKS-DVWSFGVLMW
Kinase CaMKK1.AA Pkinase_Tyr 198-215 42 0.019701 8.86 Pfam 52-70 (270) Show / Hide 
Range on Protein: 198-215
Range on HMM: 52-70/270
Sequence Identity: 42% (8 aa)

QEIAILKKL-DHVNVVKLI
.|..|.|.| .| |.|.|.
REAKIMKQLGHHPNIVRLY
Kinase CaMKK1.AA Pkinase_Tyr 128-146 26 0.070248 6.99 Pfam 1-19 (270) Show / Hide 
Range on Protein: 128-146
Range on HMM: 1-19/270
Sequence Identity: 26% (5 aa)

YKLQSEIGKGAYGVVRLAY
 ..  ..|.||.|.|....
ITFGKKLGEGAFGEVYKGT