Gene CaMK2g (Human)

CaMK2g

Species: Human
Alias: CAMK-II, FLJ16043, CaMK2g, MGC26678, CAMK2G, CAMK, CAMKG
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 10q22.1,

Classification

Group: CAMK
Family: CAMK2

Sequence

Name Sequence Type Origin Length Description Download
CaMK2g.NA RNA Sugen Kinome 3917 None Fasta, JSON
CaMK2g.AA Protein Sugen Kinome 588 None Fasta, JSON
CaMK2g.kin_dom Protein Kinase Domain Sugen Kinome 259 None Fasta, JSON

Protein domain

Protein domains of CaMK2g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK2g.AA CAMK2 14-272 94 2.9e-223 748.02 In-house 1-259 (259) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-259/259
Sequence Identity: 94% (244 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADA
|||||||||||||||||||||...|||||||||||||||||||||||||||||.|||||||||||||.||||||||||||||||||||||||||||||||
YQLFEELGKGAFSVVRRCVKKCTGQEYAAKIINTKKLSARDHQKLEREARICRKLKHPNIVRLHDSIQEEGFHYLVFDLVTGGELFEDIVAREYYSEADA

SHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP
||||.||||||||.||..|||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||
SHCIQQILESVNHCHQNGIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPP

FWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV
|||||||.|||||||||||.||||||||||||||||||||||||.||||||.||||||.
FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase CaMK2g.AA CAMK1 14-272 42 1.1e-150 441.32 In-house 1-276 (276) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-276/276
Sequence Identity: 42% (118 aa)

YQLFEELGKGAFSVVRRCVKKTS---TQEYAAKIIN-TKKLSARDH---QKLEREARICRL---LKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIV
|....|.|.||||.|..|..| .    ..|| |.|.  | ..  |    ..||.|  | .    ..||||. ...   .. . ||| .||||||||. ||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

AREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVK--LADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK---DPYGKPVDIW
 ...|.| ||.|...|||. |...|...||||||||||||...|  .. .|  .|||||.  . ..    .   |||||  ||||     .||.|..|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

ACGVILYILLVGYPPFWDED-QHKLYQQIKAGAYDFPSPEWDTVTPE-AKNLINQMLTINPAKRITADQALKHPWV
 .|||.||||.|||||.||. ...|...|| . |.||||.|| .  . ||..|..||. .| ||.|..|.|.|||.
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMK2g.AA CAMK 19-272 26 3.7e-134 435.01 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-272
Range on HMM: 1-425/425
Sequence Identity: 26% (112 aa)

ELGKGAFSVVRRCVKKTST------------QEYAAKIINTKKLS--------------------------ARDHQKLEREARICRL-------LKHPNI
.||.|.|..|..|. | .|            |..|.|||..|||.                          ..| ....|| .|...       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLHDSISEEGF-------------------HYLVF---DLVTGGEL----FEDIVAREY---------------YSEADASHCIHQILESVNHIHQHDI
..|.. .  . .                    |.|.   ....||||    |. ||....               ..|..|.....||.. |...|.|.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENLLLASKCKG--------------AAVKLADFGLAIEVQG-----------------------EQQAWFGFAGTPGYLS-PEVLRK------
|||||||||.|| .. ..              . .|..|||.|.....                       | |    | |||.| . ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DPYGKPVDIWACGVILYILLVGYPPFWDE-------------DQHKLYQQIKAGAYDFPSPE------------WDTVTPE--------AKN
        ..||...|.|.|||||||.|.|||||...             ....|...|..| ||||.|.            || .. |        .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINQMLTINPAKRITADQALKHPWV
||..||. .| ||.|..|.|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMK2g.AA RAD53 14-272 35 1.5e-112 336.62 In-house 1-305 (305) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-305/305
Sequence Identity: 35% (108 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS---ARD---HQKLEREARICRLLKHPNIVRLHDSISE-EGFHYLVFDLVTGGELFEDIVARE
| . .|||.|.|..|.....|.  | .| |||..||..    ..      ...|..| . |.||.|.|..|.. . .   |.|  |.||||||..||...
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

Y----YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGA---------------AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLR
.    ..|...     |....|. .|   |.|||||||| |.... ..                ..|..||||.  ..||..    . ||| |. |||..
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLS-KFVGEGSFMKTMCGTPQYVAPEVIT

KD---------------PYGKPVDIWACGVILYILLVGYPPFWDE-DQ----HKLYQQIKA-GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQA
.                 |.| ||.|  |.||||.| ||||| |. .|     .|..|||  | | ||.|.|| .. |||.||..||...| ||.|.|.|
SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LKHPWV
| ||| 
LNHPWM
Kinase CaMK2g.AA CDPK 14-272 40 6.30000000001e-112 344.51 In-house 1-271 (271) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-271/271
Sequence Identity: 40% (109 aa)

YQLFEELGKGAFSVVRRCVKK-TSTQEY-AAKIINTKKLSARDH-QKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFD--LVTGGELFEDIVAREYY
|.. ..||||.|..||....|  . ||  | |||. ....  .  |.. .|  | . | ||||...      | ..|.|.   ..||||||. |... ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGA----AVKLADFGLAIEVQGE----QQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWAC
.| .|.  . |||  ||..|.. ||||||||||.|. || ...     .|. |.|.. . ...     .    ..||| |..||||.|  | . .||| |
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV
||||||||.|||||. . . . ....| | |.|  |||| .. |||.||..||. .| ||..|.|||.|||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMK2g.AA S_TKc 14-272 34 3.7e-108 366.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-231/231
Sequence Identity: 34% (96 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG--GELFEDIVAREY----
|.. ...|||||..|..|..| . ...| |||.         ....|| .|..  .|||||.|.|.. . .. |.|.... |  |.||. |. | .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGK-PVDIWACGVIL
  ..| .| . ..||.. ....|.| |.||||||||.|| .      .|..||||| ..         | ||| |..||||   .||| ..|.|.||.||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALK-------HPWV
|..|.|||||.  ........|.              .||||..|...|. .|.||.|| .||.       |||.
YEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMK2g.AA DCAMKL 14-272 38 9.40000000001e-105 326.87 In-house 1-279 (279) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-279/279
Sequence Identity: 38% (109 aa)

YQLFEELGKGAFSVVRRCVKKTST-QEYAAKI-----------------INTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTG
||.    |.| |.||  |....   ..|| ||                 |. .|.    |   . | .| ...|||.|..|... . |   |||. .|.|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHM-IDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQG

GELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP
| ||. |.    ..| ||.  .... .  ...|   |||||.||||||.     .   .||.||||| .|.|.    .   ||| |  ||.|..  ||  
GDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDIWACGVILYILLVGYPPFWDE--DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWV
||||| ||||||||.|.|||  .  || .|  || .|...||.|.|| ..  ||.||..||  .| || || | ..||||
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMK2g.AA Pkinase 14-272 33 4.2e-97 333.69 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-293/293
Sequence Identity: 33% (99 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER--EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG----ELFEDIV--AR
|.. . .|.|.|..|..|..| . ...| |||. .. .   .| . |  |..| . |.|||||||.|.  ...  |.|.... ||    .||. |   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EYY--SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKG-AAVKLADFGLAIEV-QGEQQAWFGFAGTPGYLSPEVLR-KDPYGKPVDIWAC
  .  || .. ... |||. ....|.. |.||||||||.|. ...   | ||..|||||  .    ..   .|.|||.|..|||.|   .||..||.|.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILYILLVGYPPFWDE------DQHKLYQQIKAGAYDFPSPEWDTVT-----------------PEAKNLINQMLTINPAKRITADQALKHPWV
|.|||..| |.|||...      || .....|. . ..|..|.|...                  .|.| .|. .|. .|.||.||.|.|.|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CaMK2g.AA CAMKL 14-272 34 2.2e-94 301.62 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-297/297
Sequence Identity: 34% (104 aa)

YQLFEELGKGAFSVVRRCVK-KTSTQEYAAKIINTKKLS--------------ARDHQKLEREARICRLLK---HPNIVRLHDSISEEGF------HYLV
|.. ..||||.|..|. ..  .|  ...| |||. ||..               .|  ...||..| ..|.   ||||..|.. |  . .       |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FDLVTGGE--LFEDIVAREY----YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIE---V-QGEQQAWFGFAGTPG
  .. |||  ||. ||....     .| .| .   ||.. ||..|.|.|||||.||||.|| .. .   .|..|||....   .  |. |    | |.| 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

YLSPEVLRK--DPYG-KPVDIWACGVILYILLVGYPPFWDE--------DQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALK
| .||.. .  .||  ..||||.|||||| ...|| || |.        .. .|| .|. | | .|   |  |  ....|| .||. || ||.|..| ..
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWV
|||.
HPWM
Kinase CaMK2g.AA RSK 16-272 31 5.7e-92 311.86 In-house 1-278 (278) Show / Hide 
Range on Protein: 16-272
Range on HMM: 1-278/278
Sequence Identity: 31% (87 aa)

LFEE--LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDH-QKLER-EARICRLLK-HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREY---
| .   .|.|.....|.|. . . |.|| |... .|. .|.  ..  . | .|  . . ||.||.||..  .||  ||. ... |||||. .  ...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKG-AAVKLADFGLAIE-VQGEQQAWFGFAGTPGYLSPEVLR---KDP-YGKPVDIWACG
 || .|.  . .|   | |.||..|.|||||||| |....  . . .|| |||.. . .  . |    | .|  |. ||.|.   ..  ..| .|.|  |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VILYILLVGYPPFWD---EDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRIT-----ADQALKHPWV
|..| .|.|.|||     ...... ..|. | .....|.|.....|||.||..||. .|.||..     |.. ..||| 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMK2g.AA CAMK-Unique 14-272 23 1.8e-91 302.18 In-house 1-363 (363) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-363/363
Sequence Identity: 23% (85 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS-ARDHQ-----------------KLEREARICRLLKHPNIVRLHDS----ISEEG-------
| . . .|.|.|..|..|  ..   ..| |... .. .  . .|                 ||.||..| ....||||..| |        .        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------FHYLVFDLVTGGELFEDIVA--------------------REYYSE--ADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASK-------
          |.| ....||.||. |..                    . ..||  .|..  . ..|. |.. |. ||||||||.||... .        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

------CKGAAVKLADFGLAIEVQGEQQA--WFGFAGTPGYLSP--------------EVLRKDPYGKPV----DIWACGVILYILLVGYPPFWDEDQH-
      ..   .||.||||. .... .       . ||| |..|              ||.  ..|. ..    |||..|||.|..|.|.|||  |.   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLYQQIKAGAY-DFPSPEWDT---VTPEAKNLINQMLTINPAKRITADQALKHPWV
       .... |..| | .|... |.    ...|||... . .|. |..|..| ..|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMK2g.AA Ciliate-E2 14-272 25 2.2e-86 293.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-272
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

YQLFEELGKGAFSVVRRC-VKKTST----------------------QEYAAKIINTKKLSARDH-QKLEREAR----------ICRLLKHPNIVRLHDS
| . . .|.|.|..|..| |.|.                        ..|| ||.. ... .    ... || .          |...|.||||......
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IS--EEGFHYLVFDLVTGGELFEDIV------------AREYYSEADASHCIHQILE---------------SVNHIHQHD-IVHRDLKPENLLLASKCK
     .   |||.... ||.||. |             . .|..|  ... . |||.                ....|.   |.|||.||||.|.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

GAAVKLADFGLAIEVQGE-------------------------------QQAWFGFAGTPGYLSPEVLRKDP---------YGKPVDIWACGVILYILLV
   .|..||||. ... .                               |.  . ..|||||..||.|.. .         |.. .|||..|||||..| 
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GYPPFWDEDQHKLYQQIKAGAYDFPSPE--------------WDTVTPEAKNLINQ----MLTINPAKRIT-ADQALKHPWV
|.|||        .|||| . .|||.||              |. ...|.|.||..    ||  .| |||| ..|.|.||| 
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CaMK2g.AA TyrKc 14-270 20 4.8e-15 20.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-270
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

YQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLL--KHPNIVRLHDSISEE-------GFHYLVFDLVTGGELFEDIVA
 .| ..|| ||| .|.... |   .. | | ..  .     .. . ||||| . |  .|||||||.  ....       . ...|. .. .| | . . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

REY-YSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE-----QQAWFGFA---GTPG-----YLSPEVLRKDP
..   . .|  .  .|| .  ...|.. ..||||   | |....     || .||||. ..  .      .     .   |. .      ..||....  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGKPVDIWACGVILY-ILLVGYPPFWD-----EDQHKLYQQIKAGAYDFPSPE-----WDTVTPEAKNLINQMLTINPAKRITADQALKHP
.    |.|. || .. |.  | .| ..      .   .....|.| .  . |.       . ..|  ... |    .|..| |  .  .  
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CaMK2g.AA Pkinase_Tyr 14-98 26 5.2e-08 27.76 Pfam 1-94 (270) Show / Hide 
Range on Protein: 14-98
Range on HMM: 1-94/270
Sequence Identity: 26% (25 aa)

YQLFEELGKGAFSVVRRCVKK----TSTQEYAAKIINTKKLSARD--HQKLEREARICRLL-KHPNIVRLHDSIS-EEGF--HYLVFDLVTGGEL
 .. ..||.||| .|.... |      ... | |..   . . ..  .... |||.| . | .|||||||.  .. ...   .|.|. .. .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase CaMK2g.AA Pkinase_Tyr 125-167 30 0.155631 5.82 Pfam 125-164 (270) Show / Hide 
Range on Protein: 125-167
Range on HMM: 125-164/270
Sequence Identity: 30% (13 aa)

NHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGE
.. ... ..||||   | |...   .  || .|||||  .. .
EYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDIYND
CaMKII_AD CaMK2g.AA CaMKII_AD 456-583 63 1.4e-86 298.72 Pfam 1-128 (128) Show / Hide 
Range on Protein: 456-583
Range on HMM: 1-128/128
Sequence Identity: 63% (81 aa)

RKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPR
.||||.|.||..||||..||...|||.|.|..| ||.||.|||||||.||.||||....|..|..|||.|||||| .|.||||.||.|||||.| .| ..
EKQEIWKVTERWIEAIYCGDWHTYTKLCHPDMTCFEWEACGNLVEGMEFHRFYFEMHWTKRCKAVHTTMLNPHVHMYGDDAACCAYVRLTQYMDKNGMAH

TSQSEETRVWHRRDGKWLNVHYHCSGAP
| |||||||||.|||||..|| | |..|
TRQSEETRVWHKRDGKWQCVHHHRSAMP