Gene CaMK1a (Human)

CaMK1a

Species: Human
Alias: CaMK1a, CAMKI, MGC120318, MGC120317, CAMK1
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 3p25.3,

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
CaMK1a.kin_dom Protein Kinase Domain Sugen Kinome 257 None Fasta, JSON
CaMK1a.AA Protein Sugen Kinome 370 None Fasta, JSON
CaMK1a.NA RNA Sugen Kinome 1491 None Fasta, JSON

Protein domain

Protein domains of CaMK1a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMK1a.AA CAMK1 20-276 60 4.1e-220 646.65 In-house 1-276 (276) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-276/276
Sequence Identity: 60% (168 aa)

YDFRDVLGTGAFSEVILAEDKRT---QKLVAIKCIA-KEALEGKE----GSMENEIAVLHK---IKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIV
| |....|.|||||| |...|.|   .| .|||||  |.....|.     ..||||....|   |.||||... ..|||  |.||.|.||.|||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

EKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIM--ISDFGLSKMEDPGS-VLSTACGTPGYVAPEVLAQ---KPYSKAVDCW
|||.|||.||.... |.|.||.|.|..|||||||||||||||. ||||||.  |.||||||..|... ...||||||||||||||..   |||.||.|.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SIGVIAYILLCGYPPFYDEN-DAKLFEQILKAEYEFDSPYWDDISDS-AKDFIRHLMEKDPEKRFTCEQALQHPWI
||||| |||||||||||||| |..|||.|.|.||||.||.||.|||. |||||.|..|.||.||.||||.|.||||
SIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMK1a.AA CAMK 25-276 30 4.7e-139 451.06 In-house 1-425 (425) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-425/425
Sequence Identity: 30% (130 aa)

VLGTGAFSEVILAEDKRTQ------------KLVAIKCIAKEALEG---------------------------KEGSMENEIAVLHK-------IKHPNI
.||.|.|..| |...|.|.            . |||| | |. | .                           .. ....||... |       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VALDDIYE------------SGGH--------LYLIM---QLVSGGEL----FDRIVEKGF---------------YTERDASRLIFQVLDAVKYLHDLG
. | ..||            .  .        .|..|    ..|||||    ||.|||.|                .|||.|.|.. |...||.|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENLLYYSLDEDS--------------KIMISDFGLSKMEDP------------------------GSVLSTACGTPGYVA-PEVLAQ-----
||||||||||.|. . ..||              .| |.|||.... ||                        |  ..| ||||.|.| |||| .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------KPYSKAVDCWSIGVIAYILLCGYPPFYDE-------------NDAKLFEQILKAEYEFDSPY------------WDDISDS--------AK
         ..|....|.||.||| ||.||||||||..             || .|||.|.|..|.|..||            ||||||.        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFIRHLMEKDPEKRFTCEQALQHPWI
|.||.....|||||.|.||.|.|||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMK1a.AA RAD53 20-276 41 1.3e-137 412.7 In-house 1-305 (305) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-305/305
Sequence Identity: 41% (128 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-------EALEGKEGSMENEIAVLHKIKHPNIVALDDIYESG-GHLYLIMQLVSGGELFDRIV-EK
|... .||.|.|..| || .|.| . |||| | |           .|. ...||. .| |..||.|... ||...    .|... |..|||||..||  |
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

GF---YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDS---------------KIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ
..   ..| .. .. .| .||||||||.||.|||||||| |. . ||.                .| |.||||||  . ||.. | |||| ||||||.. 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

K---------------PYSKAVDCWSIGVIAYILLCGYPPFYDEND-----AKLFEQILK-AEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQAL
|                |.|.|||||.|.| ||.||||||| |. .      .|||||.. . |.|..||||.||..|||.|. .   |||||.|...||
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

QHPWI
.|||.
NHPWM
Kinase CaMK1a.AA DCAMKL 20-276 42 9.1e-122 380.77 In-house 1-279 (279) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-279/279
Sequence Identity: 42% (120 aa)

YDFRDVLGTGAFSEVILAEDKRTQ-KLVAIKC-----------------IAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGG
|.   . | | |. | .. .. |. .  | |                  |.|... |||   .||.... |||||.|. | . ..   |.||.| .|.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

ELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMI--SDFGLSK-MEDPGSVLSTACGTPGYVAPEVLAQKPYSKA
 ||| |.| . .|||||.... ..  | ||||...|||||.|||||| .  .|| .. .   |||| . ...   .|.| |||| |||||.|. . |.  
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVC-KHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

VDCWSIGVIAYILLCGYPPFYDE--NDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI
|| |..||| ||||||.|||  .  .  .||.||. ...||..||||.||||||| |.|....|||||.| || .||||.
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMK1a.AA CDPK 20-276 45 3.7e-119 367.02 In-house 1-271 (271) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-271/271
Sequence Identity: 45% (125 aa)

YDFRDVLGTGAFSEVILAEDK-RT-QKLVAIKCIAKEALEGKE--GSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQ--LVSGGELFDRIVEKGFY
|.. .|||.|.|..| .. .|  | |. ||.| |.|  .  ||   .. |||..| .. ||||. .   |.   . |..|   ...||||||.|.||| .
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

TERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDS----KIMISDFGLSKMEDP-----GSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSI
||..|.  . |.| || | |. .||||||||||.|. | ..||     | . |.|.||  |.     . ..|. |||| |.||||| .| | . .| ||.
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI
||| ||||||||||| .|| . .|.. | .|.|. | ||.|||.||| || . ..||.||....|||||||.
GVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMK1a.AA PSK 20-276 45 1.6e-116 373.94 In-house 1-258 (258) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-258/258
Sequence Identity: 45% (119 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDAS
|| . . |.| || |.  | . |..  ||| . ..  ||.|   |||  .|  ..||.|. |  ..|.   .|..|.. .|||.||||| || .||||| 
YDIKALIGKGSFSRVVRVEHRVTRQPYAIKMVETKCREGRE-FCENELNILRRVRHPYIIQLMEVFETQDRVYMVMEMATGGEMFDRIVAKGRFTERDAT

RLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGL-SKMEDPGS-VLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPP
|    |||...||| |.| ||||||||||||   ..||||| |||| ..   ..  .. | |||| |.|||||  ||| ..|| | .|||||||. |  |
RVLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMP

FYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI
| |..  .|. .||.. | .   .| ..|. |||||  |.| .. .| |  ||..|||.
FDDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase CaMK1a.AA S_TKc 20-276 38 3.7e-113 383.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-231/231
Sequence Identity: 38% (106 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSG--GELFDRIVEKGF-----
|.. ...| |||..| .. .|.|...||||.|          ....||..|.| .||||| | |.... .|||..| ...|  |.|||.|...|      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSK-AVDCWSIGVIAYI
 ..| .| ... |...|..|.|..||.||||||||.|  .      |.|.||||..        .| |||| |.|||||   .|.| ..| ||.|.| |.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ-------HPWI
.|||||||.  .....|..|.              |..||||||....|||||| |. .|||       |||.
MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMK1a.AA Ciliate-E2a 20-276 39 1.3e-112 332.74 In-house 1-275 (275) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-275/275
Sequence Identity: 39% (108 aa)

YDFRDVLGTGAFSEVILAEDKRTQKL-VAIKCIAKEALEG-KEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKG-FYTE-
|.| ...|.|.|  | ||. |.| |  ...| | | . .. .. ...|||. . ...||||  | ..||.  ..||.| ...||||.|.|.... | .| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

RDASRLIFQVL-DAVKYLHDLGIVHRDLKPENLLYY--SLD--EDSKIMISDFGLSKME--DPGSVLSTACGTPGYVAPEVLAQKP------YSKAVDCW
 ...... | | ... |.| ..|.||||||||.|.   | .  ..|.|.|.||||..    | . .. . ||||||||||||. |       |.. .| |
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

SIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPY-WDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI
|.||| ||||||.|||. .. .  ..|. | .. |..|  | ..|...||... . ||||.||.|..|||.||| 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CaMK1a.AA CAMK-Unique 20-276 26 3.9e-110 364.83 In-house 1-363 (363) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-363/363
Sequence Identity: 26% (96 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSM-------------------ENEIAVLHKIKHPNIVALDDI----YESGG-------
|..  ..|.|.|..|. . |. | |. |.| . |.. . | .                     ..|.... . .||||. | |.    ..          
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------HLYLIMQLVSGGELFDRIVE--------------------KGFYTE--RDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSL-DE----
        ..|..|... ||.||| |..                    .| ..|  .|........| ||.|.|...|||||||.||.....  ..    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

--------DSKIMISDFGLSKMEDPGSVLS---TACGTPGYVAP--------------EVLAQKPYSKAV----DCWSIGVIAYILLCGYPPFYDENDA-
        ...| ..||||.. ..   . .   | |||| |.||              ||... .|.  .    |.||.|||.|..|||.|||. |... 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------KLFEQILKAEY-EFDSPYWDD---ISDSAKDFIRHLMEKDPEKRFTCEQALQHPWI
       ..|| |.|..| .||...|..   ||..||||.  .|. || .| .....|.|.||
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMK1a.AA Pkinase 20-276 35 3e-103 354.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMEN----EIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGG----ELFDRIV--E
| .  ..| |.|..| .. .| |.|.||.|.| |.  | ..  ...    ||.......||||| | |..|...|.|..| .. ||    .|||.|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

KGFY--TERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYY-SLDEDSKIMISDFGLSKM--EDPGSVLSTACGTPGYVAPEVLA-QKPYSKAVDCWS
.| .  .|... . . |.| ...|.|. ||.||||||||.|.    . |... |.||||.|   . ..| ..| ||||.|.||||.  ...|...|| ||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVIAYILLCGYPPFYDE------NDAKLFEQILKAEYEFDSPYWDDIS-----------------DSAKDFIRHLMEKDPEKRFTCEQALQHPWI
.|.| |..|||.|||...      .. .....|......||.|.|..||                 ...||||. . .|||.|| |.||.|||||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CaMK1a.AA CAMKL 20-276 37 2.3e-101 324.25 In-house 1-297 (297) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-297/297
Sequence Identity: 37% (113 aa)

YDFRDVLGTGAFSEVILAED-KRTQKLVAIKCIAKEALEGKEGSMEN--------------EIAVLHKIK---HPNIVALDDIYESGGH------LYLIM
|.. ..||.|.|..| ||.. . |.. |||| | |. .  .. .. |              ||. . ...   ||||. | ...|   |      .||.|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

QLVSGGE--LFDRIVEKGF----YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDS--KIMISDFGLSKMEDP-----GSVLSTACGTP
 ..||||  |||.||..|      .|..| |.  |...||.|.|..||||||.||||.|   |||.   .| |.|||.| | .|     |  |.| ||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL---LDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

GYVAPEVLAQ--KPYS-KAVDCWSIGVIAYILLCGYPPFYDENDA-------KLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQ
 | |||...   |||  ..||.||.||| | ..||| || |....       .|...| .  |..  | | ..| ...|.||......||||.|..| ..
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYP--PIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

HPWI
||| 
HPWM
Kinase CaMK1a.AA RSK 22-276 32 2.4e-93 316.41 In-house 1-278 (278) Show / Hide 
Range on Protein: 22-276
Range on HMM: 1-278/278
Sequence Identity: 32% (90 aa)

FRDV--LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEG---SMENEIAVLHKIK-HPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGF---
 ..   .| |... .   ... |... | | . |  .  ..        |. .|  .. ||.|| | . .. .|.|||||....|||||... ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

YTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDED-SKIMISDFGLSKM--EDPGSVLSTACGTPGYVAPEVLA---QKP-YSKAVDCWSIG
 .|..|.  . ..  ||..||..||.|||||||| || . . .   |...|||..|    | .. . | |.|  |.|||.|.   |.  ..||.| || |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VIAYILLCGYPPFYD---ENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFT-----CEQALQHPWI
|. | .| |.|||.    .| ......|.|... ...| |. .|. |||.||.....||.|| .      |. .||||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMK1a.AA TyrKc 20-276 22 3.3e-16 39.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKI--KHPNIVALDDIYESG-------GHLYLIMQLVSGGELFDRI-VE
  . ..|| ||| || ... |     ||.|.. ..|    .  . .|. ...|.  .|||||.|  .  ..       . |...| ....| | |..   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPG-------SVLSTAC--GTPG-----YVAPEVLAQKPY
..  . .|     .|. .   |||. ...||||   | |   ..|.  . |||||||.  . .       .. ...   |. .       |||..  . .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL---VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SKAVDCWSIGVIAY-ILLCGYPPFYD-----ENDAKLFEQILKAEYEFDSPY-----WDDISDSAKDFIRHLMEK----DPEKRFTCEQALQHPWI
. . | || ||  . |.  | .| ..      ... ..|.. . ..    |.            . | .  .|..    |||.| | ..   |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF----VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase CaMK1a.AA Pkinase_Tyr 20-142 27 4e-15 51.85 Pfam 1-137 (270) Show / Hide 
Range on Protein: 20-142
Range on HMM: 1-137/270
Sequence Identity: 27% (38 aa)

YDFRDVLGTGAFSEVILAEDK----RTQKLVAIKCIAKEALEGKE---GSMENEIAVLHKI-KHPNIVALDDIYE-SGGH--LYLIMQLVSGGELFDRIV
  |  .|| ||| || ... |     |.  ||.|.. ||    ..    .. .|....... .||||| |  .    |..  .|..| .. .| | |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KGFYTERDASRLIFQVLDAVKYLHDLGIVHRDL
.    |.  |  |     .|. ..  ||.. ...||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL