Gene BRSK2 (Human)

BRSK2

Species: Human
Alias: PEN11B, C11orf7, BRSK2, SAD1, FLJ41362, STK29
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 11p15.5,

Classification

Group: CAMK
Family: CAMKL
Subfamily: BRSK

Sequence

Name Sequence Type Origin Length Description Download
BRSK2.AA Protein Sugen Kinome 736 None Fasta, JSON
BRSK2.kin_dom Protein Kinase Domain Sugen Kinome 252 None Fasta, JSON
BRSK2.NA RNA Sugen Kinome 2594 None Fasta, JSON

Protein domain

Protein domains of BRSK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase BRSK2.AA BRSK 19-270 88 1.5e-231 775.53 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-254/254
Sequence Identity: 88% (224 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLS--ESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK
|||||||||||||||||||||||..||||||.|.||||  ||.||||||||||.|||.||||.|..|||||||||||.||||||||||||||||||||||
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPF
|||||||||||||||||||.|||||||||||||||||||.|||||||||||.|..|.|||||||||||||||||||||||||||||||||.|||||||||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
|||||||||||||||||||||||.||||.|||||||||...|..|..||||.||
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase BRSK2.AA CAMKL 19-270 42 7.4e-149 478.27 In-house 1-297 (297) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-297/297
Sequence Identity: 42% (127 aa)

YRLEKTLGKGQTGLVKLGVH-CVTCQKVAIKIVNREKLS--------------ESVLMKVEREIAILKLIE---HPHVLKLHDVYENKKY------LYLV
||..||||||  | |||..|   | .||||||....|..              ||.. ...|||.|.|..    ||.. ||..|.|....      .|||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

LEHVSGGE--LFDYLVKK----GRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKN--NIRIADFGMASLQV-G----DSLLETSCGSPHY
.|..||||  ||||.||.    ||....|||..||||.||...|||| |.|||.||||.||||..  || |.|||.. ..  .    . .|.|.||||.|
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

ACPEVIRG--EKYDGRKADVWSCGVILFALLVGALPFDDD--------NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMIEVDAARRLTLEHIQKHIW
..||.. |  ..|||.|.|.|||||||.|...|.||||||        |   |..|...| ...|..  .. ||..|.|.| .|.  .| |.. | .| |
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

Y
.
M
Kinase BRSK2.AA AMPK 19-270 49 7.29999999999e-143 426.93 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-254/254
Sequence Identity: 49% (125 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKL-SESVLMKVEREIAILKLIEHPHVLKLHDVY-ENKKYLYLVLEHVSGGELFDYLVKKGRLTPK
| ..||.|.|  | ||.|.|  | .|||||| |..|. ....  ...||| ||||. |||. .| .|  | .. ...|.|.||||||||| ||.|||. .
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPF
||..|| ||||... || | | ||||||||||||...|| |.|||   .     .| |.|||| || ||.| | .| |.. |.|||||||.|.| | |||
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

DDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
||.| ..|  |.| |..  | |. |....|...| .||   |.| . | .| |.
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase BRSK2.AA CAMK 24-270 29 4.7e-130 421.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 24-270
Range on HMM: 1-425/425
Sequence Identity: 29% (124 aa)

TLGKGQTGLVKLGVHC-VTC-----------QKVAIKIVNREKLS--------------------------ESVLMKVEREIAILKL-------IEHPHV
|||.|. | |||..|   |.           |||||||....||.                          .. . .|.|||.|.|.       . ||..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLHDVYEN-------------------KKYLYLVL---EHVSGGEL----FDYLVKK---------------GRLTPKEARKFFRQIISALDFCHSHSI
.||..|||.                   .|..|.|.   |..|||||    |||.|..               ||.| .|||..||||.||...|||| |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENLLLDEK-----------------NNIRIADFGMASLQVG------------------------DSLLETSCGSPHYAC-PEVIRG------
.||||||||.|||..                 ||| |.|||.|    .                        . ...|.||.|.|.. |||..|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EKYDGRKADVWSCGVILFALLVGALPFDDD-------------NLRQLLEKVKRGVFH-MPHFIPP-----------------------DCQS
       ..|.|.|.|.|||||||...|.| .||..|             |...|.||...| ..  |....|                       .|..
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRGMIEVDAARRLTLEHIQKHIWY
|.|.| .||  .|.|.| . .| |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase BRSK2.AA QIK 19-270 44 2.5e-117 396.07 In-house 1-272 (272) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-272/272
Sequence Identity: 44% (121 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGR------
| .|.|.|||  . |||. | .| .||||||. ...| |. | |..||..|.|...|||. || .| | ....|.| |  |.||.||||.|.||      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKAD
              .. .|||. | ||.|| ..||.. | ||||| ||.|||.  || |||||.  .. .. ||.| |||| || ||.  |..||| |.|
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKVD

VWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
.|| ||.|..|  |||||| ..| .| ..|  | | .| |.. ||..| | |  ||...|.| . | .| | 
IWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase BRSK2.AA NuaK 19-270 42 4e-116 306.89 In-house 1-252 (252) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-252/252
Sequence Identity: 42% (108 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKL-SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKE
|...||||||  | |||..   | ..|||| . ..|  .|  .... ||| |.  ..|||. . . |.|||  . .|.|  |||||.||. ....|. .|
YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIEDEQDMVHIRREIEIMSSLNHPHIIHIYEVFENKDKIVIVMEYASGGELYDYISECKSLPERE

ARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFD
||.|||||.||. .|| | ||||||| || |||...|..|||||. ..   . .|.| |||| || ||.. |. | |   | || ||.|...  | .|||
ARHFFRQIVSAVHYCHKHRICHRDLKLENILLDQNCNAKIADFGLSNYYHDQKFLHTFCGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFD

DDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
 .. ..|   ...| .  |.  | |   | | |  |.  || |.. | .| | 
GHDFKHLVKQISQGAYYEPC-KPSDACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase BRSK2.AA MARK 19-270 41 1.3e-115 379.29 In-house 1-262 (262) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-262/262
Sequence Identity: 41% (110 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSE-SVLMKVEREIAILKLIEHPHVLKLHDVYE--NKKY-LYLVLEHVSGGELFDYLVKK--GR
|.. ||.|.|  . |||..|  | .||||||....||..   . .|.|||.|.|...||.. ||..| |  ...  .||..|..|||||.||....  ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKN--NIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
|. .|||..||||.||. .|||..|.|||.||||.|.||..  || |.|||..     ...|.| ||.| |..||.. ...|||.|.|.||.||.|....
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGALPFDDDN--LRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
.| .|||.|.  . .| .|. ||... |......|..|.. .. |.  .| |.| | || | 
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase BRSK2.AA GIN4 63-270 55 8.70000000001e-105 335.7 In-house 81-293 (293) Show / Hide 
Range on Protein: 63-270
Range on HMM: 81-293/293
Sequence Identity: 55% (118 aa)

VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFG
.|||| |.|||.|| |..|.||.|... |||||| . .||||.|||..|.|  .|| ..|||||  . .||.  ||||||||||||||.|.| |.|||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

MASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD--NLRQLLEKVKRGVFHMPHF--IPPDCQSLLRGMIEVDAAR
|| |..   |||||||||||| ||.. |  |.|  .||||||||||||| | ||||..  |.|.|| ||..| ..||    |  . | |.| .. ||  .
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RLTLEHIQKHIWY
|..   | ||   
RIKTRDILKHPLI
Kinase BRSK2.AA S_TKc 19-270 35 2.4e-101 343.93 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG--GELFDYLVKKGR----
|.. ...|||  | |....|  | ..|||||..          ...|||.|||   ||.. ||.||... ..||.|.|...|  |.||||..|.||    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALL
  ... .||....||..||..|||| |.||||||||.||||  .| |.|||.| .        | ||.|.|  |||.   .|...|.|.||||.||. .|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQK-------HIWY
.|  ||.  .. ....|..          .|.. ...|.. ..| ..|.|   . .       | | 
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase BRSK2.AA Pkinase 19-270 31 8.4e-98 336.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVER--EIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGG----ELFDYLV--KK
|......|.|  | |....|  |...||.||..... ......   |  ||.|.| . ||....|.|..|.|...|.|.|.. ||    .||||.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GRL--TPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNI----RIADFGMASL--QVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSC
|..  ...|......||...|..|||..|.||||||||.|.|....|    .|.||| | .     .| . | ||.|.|. |||||| .|.|.|.|.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVILFALLVGALPFDDD------NLRQLLEKVKRGVFHMPHFIP---------------------PDCQSLLRGMIEVDAARRLTLEHIQKHIWY
|.||. .| | .||...      . .|........ .| . . .                     ..|..........| ..|.| |.| .| | 
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase BRSK2.AA MELK 19-270 41 2e-88 300.05 In-house 1-254 (254) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-254/254
Sequence Identity: 41% (105 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEA
| . ...| |  . ||| .| .| |.|||||.....|  . | .|. |.  || ..| |. .|. . | .. ...|.|. .|||.|||.... ||  .|.
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG-HDLPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEET

RKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVG--DSL-LETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP
|.|||||.||. . ||    ||||||||||.||. .... |||. .   |  |   |.| |||| || ||.|.| .| |  ||||| |..|..|..|.||
RHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLP

FDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
|||||.. .  |. .|... |... |  . ||| |. ||  .|. . .. .| | 
FDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV
Kinase BRSK2.AA TSSK 19-270 33 3e-87 286.4 In-house 1-289 (289) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-289/289
Sequence Identity: 33% (97 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQK----------------VAIKIVNREKLSESVLMK-VEREIAILKL-IEHPHVLKLHDVYENKK-YLYLVLEHVS
| ..|..|.|  . |.....  .  |                |||||..| | .. .|.|   ||| |..  . ||.. ...  .|.     |.|.|  .
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYAE

GGELFDYLVKK------GRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDS------LLETSCGSPHYACPEVI
.| |..|  ..      |.|. ..|||.|||..||...|||| . ||||| ||.|||. .|| ..||| |  .  |.      |..| |||  ||.||..
HGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEIL

RGEKYDGRKADVWSCGVILFALLVGALPFDD--DNLRQLLEKVK-RGVFHMP---HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY
|| .||. ..||||.||||.....| .||||   |....|. .. ..|       ..| ..|..|.| | . .. .|.... |..| |.
RGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDKSNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase BRSK2.AA Pkinase_Tyr 19-163 30 5e-22 75.23 Pfam 1-158 (270) Show / Hide 
Range on Protein: 19-163
Range on HMM: 1-158/270
Sequence Identity: 30% (49 aa)

YRLEKTLGKGQTGLVKLGVHC----VTCQKVAIKIVNREKLSESV--LMKVEREIAILKLI-EHPHVLKLHDVYE-NKKY--LYLVLEHVSGGELFDYLV
 .. |.||.|. | |..|.       |...||.|.. .|. ...   . .  ||..|.| .  ||....|. |    ..   .|.|.|.. .| | ||| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----KGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMA
|    |..||.|.  .. .|| ..... .|. . ||||   | |..|.| ..|.|||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase BRSK2.AA TyrKc 19-268 24 2.4e-17 57.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-268
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLI--EHPHVLKLHDVYENK-------KYLYLVLEHVSGGELFDYLVK
 .|.|.|| |. | | .|.     ..||.| .. ..     ..   ||. |.. .  .||....|. |   .       . |..|.|....| | ||| |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGR-LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-------SLLETSC--GSP-----HYACPEVIRGEKYDG
... |..|.  .|  || .  .. ||. . ||||   | |..|.. ..|.|||..     |       .   ..   |.          ||.|.  |.  
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-

RKADVWSCGVILFALL-VGALPFDD-----DNLRQLLEKVKRG-VFHMPHF--------IPPDCQSLLRGMIEVDAARRLTLEHIQKHI
 | |||| || .. ..  |. |  .      . ....|.||.|     |.          |..  .. .   . |.. | | . | . .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase BRSK2.AA GIN4 19-55 37 3.4e-08 21.82 In-house 1-37 (293) Show / Hide 
Range on Protein: 19-55
Range on HMM: 1-37/293
Sequence Identity: 37% (14 aa)

YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKL
..| .|||.| || |.|  .  | |. |.|.. . |.
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKI
UBA_CAMKL BRSK2.AA UBA_CAMKL 299-338 24 1.3e-12 43.4 In-house 1-41 (41) Show / Hide 
Range on Protein: 299-338
Range on HMM: 1-41/41
Sequence Identity: 24% (10 aa)

DPDVLDSMHSLGCFRDRNKLLQDLLSEEE-NQEKMIYFLLL
|..... | ..... ||... . |..    |.....|.|||
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL