Gene ALK7 (Human)

ALK7

Species: Human
Alias: ALK7, ACVRLK7, ACVR1C
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 2q24.1,

Classification

Group: TKL
Family: STKR
Subfamily: STKR1

Sequence

Name Sequence Type Origin Length Description Download
ALK7.AA Protein Sugen Kinome 493 None Fasta, JSON
ALK7.kin_dom Protein Kinase Domain Sugen Kinome 288 None Fasta, JSON
ALK7.NA RNA Sugen Kinome 9010 None Fasta, JSON

Protein domain

Protein domains of ALK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Activin_recp ALK7.AA Activin_recp 26-100 24 9.6e-27 90.42 Pfam 1-121 (121) Show / Hide 
Range on Protein: 26-100
Range on HMM: 1-121/121
Sequence Identity: 24% (30 aa)

LKCV-CLL--------CD--SSN-----FTCQT----------EGACWASVMLTNG---KEQVIK----SCVSLPELNAQ---VFCHS-----SNN---V
|||. |          |.   .|     .||.|          .|.|..|......   .||...    .|.||.|.  |     |.|     |..    
LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG

TKTEC-CF-TDFCNNITLHLP
...|| |  ||.||..  ..|
HNHECWCCETDYCNRNLTPPP
Kinase ALK7.AA Type1 195-482 72 1.8e-276 758.81 In-house 1-290 (290) Show / Hide 
Range on Protein: 195-482
Range on HMM: 1-290/290
Sequence Identity: 72% (209 aa)

IVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIK
|...|..||||.||||.|.|.||.||||||.||||||||||.|||||||.||||||||||||.||||.||||||...|||.|||||||||..... .|..
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR

LALSIASGLAHLHMEIVGTQ--GKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIY
||.|.|.|||||||||.|||  |||||||||||||||.|||...|.||||||||.|..  ..|||.|||.||||||||||.||.|||.| |||.|.||||
LAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADIY

SVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTI
|.|||.|||||||.||||||.|||||||.||.|||.|.||||||..|.||.|||.|||....|.|...|.||||.|..||.||||||||.
SFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL
Kinase ALK7.AA STKR 195-482 60 2.8e-220 718.24 In-house 1-312 (312) Show / Hide 
Range on Protein: 195-482
Range on HMM: 1-312/312
Sequence Identity: 60% (188 aa)

IVLQEIVGKGRFGEVWHGRWCG----EDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDN-GTWTQLWLVSEYHEQGSLYDYLNRNIVTV
|.|.|..||||.||||.|.|.|    |.||||||.||||.|||||.|||||.|.||||||.|||||.|.. |.|||.||..||||.|||.|||.|.....
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW

AGMIKLALSIASGLAHLHMEIV--GTQ--GKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIP-------QNPKVGTKRYMAPEMLDDTM
 .|...|.|.|.|||||||||.  |||  .|||||||||||||||||.. ||.|||.|||..||.  |.|||.       ||..||||||||||.||..|
HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM

NVNIFES-FKRADIYSVGLVYWEIARRCSVGG------IVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQ-SCEALRVMGRIMRECWYANGA
|.. ||| |||.|.|..|||.|||||||..||      ||.|||.|.||.||..||.|.|.|||| ...||.|||.|. ...|.|.|  .|.|||.....
NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE

ARLTALRIKKTI
||||||..|||.
ARLTALCVKKTM
Kinase ALK7.AA Type2 195-482 39 1.9e-113 375.95 In-house 1-315 (315) Show / Hide 
Range on Protein: 195-482
Range on HMM: 1-315/315
Sequence Identity: 39% (124 aa)

IVLQEIVGKGRFGEVWHGRWCGE-----DVAVKIFSSRDERSWFREAEIYQT-VMLRHENILGFIAADN-KDNGT--WTQLWLVSEYHEQGSLYDYLNRN
| | |..||||||.|| ..| ..     .||||||. .|  ||  | .||.. ....||||| ||.|.  .  ..  | ..|||.|.|. |||.||| ..
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH

IVTVAGMIKLALSIASGLAHLHMEIV-GTQ---GKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNT----IDIPQNPK----VGTKRYMAPEM
...   . ..|.|.| |||||| ||  ..|    ||.||||||||||.|||   ||.|||.|||.. .   ..       |. ..    |||.||||||.
TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV

LDDTMNVN-IFESFKRADIYSVGLVYWEIARRCSVGG---IVEEYQLPYYDMVPSD-PSIEEMRKVVCDQKFRPSIPNQWQSCEALR-VMGRIMRECWYA
|. ..| .   ..||..|.|. |||.||.. ||.. .    | |||.|.   | .  ||.|.|. .|   . || .|. |.  ...  .    . .|| .
LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH

NGAARLTALRIKKTI
   |||||. ..  .
DAEARLTAQCVQERM
Kinase ALK7.AA TKL 201-482 31 2e-104 353.22 In-house 1-364 (364) Show / Hide 
Range on Protein: 201-482
Range on HMM: 1-364/364
Sequence Identity: 31% (117 aa)

VGKGRFGEVWHGRWCG----------EDVAVKIFSSRD-------------------------ERSWFREAEIYQTVM---LRHENILGFIAADNKDN--
.|.|.||||..|.| |          .|||||.|.|..                         | ||||. |.....|   |||.||. |.....  .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------GTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIV--GTQGKPAIAHRDIKSKNILVKKCET--------------C
       |.|.||..| ||.. |||..||.        ....||.||.|...||...   .|  ||.|.|||.|||||||..  |              |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

AIADLGLAVKHDSILNTIDIP---------------QNPKVGTKRYMAPEMLDDTMNVNI----------FESFKRADIYSVGLVYWEIARRCSVGGIVE
 |.|.||.  ..   |  |.                 ....||.|.||||.|...|| .           || ....|.|| |.| |||. ||       
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----P

EYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQS-------CEALRVMGRIMRECWYANGAARLTALRIKKTI
.|..||..|...|| .||| ..||| . || ||..||.         ... | ..| .|| ..  .|.....|.|..
YYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ALK7.AA Pkinase 195-482 20 1.4e-43 155.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 195-482
Range on HMM: 1-293/293
Sequence Identity: 20% (67 aa)

IVLQEIVGKGRFGEVWHGRWCGED--VAVKIFSSRDERSWFREA-----EIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQG----SLYDYLN
... ...|.| ||.|..... |.   |||||.. |.|.||....     ||.   .|.|.||. .. .        . ...| ||.| |    .|.||. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS

---RNIV--TVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETC----AIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEML
   .. .  .    .. .. |..||...| .         | |||.|. |||...  ..     |.| ||| ..|   .  .   .  .|| .|||||  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEV-

DDTMNVN-IFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEAL-----------------RV
     ..   .  ...|..|.|.. .| . .           .|... .  ...  ......|  . .|   . ...|.                   . 
-----IRGGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEE

MGRIMRECWYANGAARLTALRIKKT--I
.  ... |.  . . |.||  |..   .
CKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ALK7.AA MLK 195-401 26 6.5e-34 115.07 In-house 1-229 (291) Show / Hide 
Range on Protein: 195-401
Range on HMM: 1-229/291
Sequence Identity: 26% (66 aa)

IVLQEIVGKGRFGEVWHGRWCGED-----VAVKIFS-------SRDERSWFREAEIYQTVMLRHEN----ILGFIAADNKDNGTWTQLWLVSEYHEQGSL
| ..|..|.| ||.|| ||| ..|     ||||..        . .. .|  | |...  .|.|.|    |  | .. ....    .. .|.|| | |||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL

YDYLNRN---------------IVTVAGMIKLALSIASGLAHLHMEIVGTQGKP-AIAHRDIKSKNILVK------KCETCAIADLGLAV-KHDS---IL
|..|. .               ..... ... || .|.|.. ||..      .| .| |||.||.|||.       . .|. |.| |..  .|..     
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM

NTIDIPQNPKVGTKRYMAPEML----DDTMNVNIFESFKRADIYSVGLVYWEI
...        || ..||||..     .. .       . .|..| |.| ||.
SNA--------GTYAWMAPEVIQQFRCEKYS-------EKCDVWSWGVVLWEM
Kinase ALK7.AA TKL-Unique 197-405 28 2.6e-24 82.75 In-house 1-225 (290) Show / Hide 
Range on Protein: 197-405
Range on HMM: 1-225/290
Sequence Identity: 28% (66 aa)

LQEIVGKGRFGEVWHGRWCGEDVAVKIFS-SRDERSWFRE---AEIYQTVMLR-HENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLN--------
  . .| | .|.| .| | |..||.|.|.   | .. ...    |.    .|. |.||. ....  ..  .  .. .|.|| . |||||.|.        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

--RNIV-TVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKC-----ETCAIADLGLAVKHDSILNTIDIPQN-----PKVGTKRYMA
  .|.  . . ..|.|. ||.|. .|| ..     .| |.|||.||.|.||            |.| ||.   ..|.... .  .      ..|. |.||
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCE-----PP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA

PEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRC
||.| .      .   . .|.|| | | |||| |.
PEVLRMNF----CQYSEKSDVYSFGIVLWEIATRK
Kinase ALK7.AA STE 195-402 20 1.7e-21 72.76 In-house 1-262 (359) Show / Hide 
Range on Protein: 195-402
Range on HMM: 1-262/359
Sequence Identity: 20% (58 aa)

IVLQEIVGKGRFGEVWHGRWC-----------------GEDVAVKIFSSRDERS---------------WFRE---AEIYQTVMLR--HENILGFIAADN
  ..|..||| ||.|  ..                   || .|.|. . .....                 ..    ||     ..  |.||  .. .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KD---NGTWTQLWLVSEYHEQGSLYDYLNRNIVTV--------------AGMI-KLALSIASG-LAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCA
|.   ..  ..||.. || . ||| | ....  .                  | . . .|  | |..||           | |||||. |||.     . 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--------IIHRDIKPANILL-----VK

IADLGLAVKHDSILN------------TIDIPQNPKVGTKRYMAPEMLDD-TMNVNIFESFK----RADIYSVGLVYWEIA
..| |.. . ....             |..   |  |||  .||||...  . . .     |    ..||.|.|.. .| |
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R----DKGYDTKCDIWSLGCTIIEMA
Kinase ALK7.AA S_TKc 195-460 21 3.2e-21 77.75 SMART 1-231 (231) Show / Hide 
Range on Protein: 195-460
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

IVLQEIVGKGRFGEVWHGRWCG--EDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQ--GSLYDYLNRNI----
  . ...||| ||.|. .|. .  . ||.|| .    ..  || .| .    .|.||  .. .        . |..| || ..  |.|.||. ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---VTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIF
    .     ...  |...|...|        .  | |||.|  |||. .  .  |.| ||| .            .  .||  |||||.|         
RFPFPE-HARFYMYQICCALEYCH-------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---------

ESFK--RADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVC-DQKFRPSIPNQWQSCEALRVMGRI
 ..   ..|..|.| . .| . ..       ..|. .  .. |.. .. .||  . | . ||..    |.... . .  .
-GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ALK7.AA TK 195-350 15 1.9e-20 64.6 In-house 1-311 (486) Show / Hide 
Range on Protein: 195-350
Range on HMM: 1-311/486
Sequence Identity: 15% (49 aa)

IVLQEIVGKGRFG---EVWHGRWCG---------------------------EDVAVKIFS---SRDERSWFR-----------------EAEIYQTVML
|.| .  |.| ||   ||. |.| |                           ..||||.     . ...  |                  |... .  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHENILGFIAADNKDNGTW--------TQLWLVSEYHEQGS----LYDYLNRN-----------------------------------------------
.|.||. ....  .. .            ...| || . |.    | ||| ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------IVTVAGMIKLALSIASGLAHLHME---IVGTQGKPAI---AHRDIKSKNILVKKCET-----------CA
                              ..|.. ..  .. ||.|...||              |    |||.   |.|| .  .           | 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF--------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK

IADLG--------LAVKHDS
||| |        || ...|
IADFGLSRQGSGVLARDIYS
Kinase ALK7.AA CAMK 200-374 18 5.7e-20 60.38 In-house 1-292 (425) Show / Hide 
Range on Protein: 200-374
Range on HMM: 1-292/425
Sequence Identity: 18% (56 aa)

IVGKGRFGEVWHGRWCGED--------------VAVKIFS-------------------------------SRDERSWFREAEIYQTVM-----LRHENI
. |.|.||.|  ..                   ||.|| .                                .|... .|| || ...      |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LGFIAADN--------KDNG-TWTQ--------LWLVS---EYHEQG----SLYDYLNRN-----------IVTVAGMI------KLALSIASGLAHLHM
. .. .           | . | ..        ...|    || . |     |.||. ..           ||   | .      ..   |.|.....| 
IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS

EIVGTQGKPAIAHRDIKSKNILVKKCE-----------------TCAIADLGLAVKHDSILNTI-------------------DIPQNPKVGTKRYMA-P
          |.|||.|  |||. . .                 .  |.| |.| | |.  |                     . . .  .||  ||| |
H--------NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP

EML
|.|
EVL
TGF_beta_GS ALK7.AA TGF_beta_GS 165-193 72 7.2e-17 58.5 Pfam 1-29 (29) Show / Hide 
Range on Protein: 165-193
Range on HMM: 1-29/29
Sequence Identity: 72% (21 aa)

KTLKDLIYDVTASGSGSGLPLLVQRTIAR
||..|...| . |||||||||||||||||
KTMQDMMEDFCTSGSGSGLPLLVQRTIAR
Kinase ALK7.AA Pkinase_Tyr 195-307 27 2.9e-16 55.69 Pfam 1-128 (270) Show / Hide 
Range on Protein: 195-307
Range on HMM: 1-128/270
Sequence Identity: 27% (36 aa)

IVLQEIVGKGRFGEVWHGRWC------GEDVAVKIF--SSRDE----RSWFREAEIYQTVML-RHENILGFIAADN-KDN-GTWTQLWLVSEYHEQGSLY
|.. .  |.| ||||..|.|       . .||||.   .. .|    .. .|||.|     | .|.||. ....   ..  .   |...| || . |.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMK--QLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLL

DYLNRN-----IVTVAGMIKLALSIASGLAHLH
||| ..      .|.  ... .. ||.|...|.
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE
GS ALK7.AA GS 165-195 67 1e-15 59.42 SMART 1-31 (31) Show / Hide 
Range on Protein: 165-195
Range on HMM: 1-31/31
Sequence Identity: 67% (21 aa)

KTLKDLIYDVTASGSGSGLPLLVQRTIARTI
||..|...| . ||||||||||||||.||.|
KTMHDMMEDTCTSGSGSGLPLLVQRTVARQI
Kinase ALK7.AA TyrKc 195-482 25 8.5e-15 16.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 195-482
Range on HMM: 1-280/280
Sequence Identity: 25% (80 aa)

IVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVML--RHENILGFIAADNKD--NGTW---TQLWLVSEYHEQGSLYDYLNRNI-
|.| .. | | ||||..|.|  ..||||   .  ..   |||.|    .|  .|.||. ....  ..  |  .    .|..| || . |.| ||| ..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMC--KLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKHRP

-VTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSI----LNTIDIPQ----NPK-VGTKRYMAPEMLDD
 .... ... .. ||.| ..||           . |||.   |.||..  |. |.| ||. ....      ..  . .    . | .   | |||| .  
KLCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--

TMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCE-----ALRVMGRIMRECWYANGAA
  | ..| .    |..| | . |||  ..         | ||..|.  . | .|... | . . .|  ||     .     .   | .||..|| .. . 
--NYGKFTTK--SDVWSFGVCMWEIFTYG---------QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPED

RLTALRIKKTI
| |   |.. .
RPTFSEIHECF
Kinase ALK7.AA Dicty4-Unclassified 293-345 43 3.8e-11 34.39 In-house 112-156 (263) Show / Hide 
Range on Protein: 293-345
Range on HMM: 112-156/263
Sequence Identity: 43% (23 aa)

IKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLA
|| |..|| |..|||           . |||||| |||. |     |||.|..
IKYAFDIAQGMQHLHTR--------NFIHRDIKSSNILMDKHFNIKIADFGIS
Kinase ALK7.AA Dicty4-Unclassified 196-226 51 7e-08 23.04 In-house 3-32 (263) Show / Hide 
Range on Protein: 196-226
Range on HMM: 3-32/263
Sequence Identity: 51% (16 aa)

VLQEIVGKGRFGEVWHGRWCGEDVAVKIFSS
..|.| ||| | .|  | | | |||||.| .
IDQFI-GKGHFSKVHKGNWKGKDVAVKKFNE
Kinase ALK7.AA TK 459-482 20 0.018713 3.18 In-house 463-486 (486) Show / Hide 
Range on Protein: 459-482
Range on HMM: 463-486/486
Sequence Identity: 20% (5 aa)

RIMRECWYANGAARLTALRIKKTI
..|..|| .. . | |   ... .
DLMQQCWHYDPEDRPTFSQLHEQL
Kinase ALK7.AA Pkinase_Tyr 321-345 44 2.361158 1.82 Pfam 134-158 (270) Show / Hide 
Range on Protein: 321-345
Range on HMM: 134-158/270
Sequence Identity: 44% (11 aa)

HRDIKSKNILVKKCETCAIADLGLA
|||.  .|.||..  .. |.| |||
HRDLAARNCLVTENNVVKICDFGLA