Gene ADCK4 (Human)

ADCK4

Species: Human
Alias: FLJ12229, ADCK4, COQ8
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 19q13.1,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-A

Sequence

Name Sequence Type Origin Length Description Download
ADCK4.AA Protein Sugen Kinome 544 None Fasta, JSON
ADCK4.NA RNA Sugen Kinome 2458 None Fasta, JSON
ADCK4.kin_dom Protein Kinase Domain None 303 None Fasta, JSON

Protein domain

Protein domains of ADCK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK4.AA ABC1-A 210-406 57 2.5e-161 542.24 In-house 1-216 (216) Show / Hide 
Range on Protein: 210-406
Range on HMM: 1-216/216
Sequence Identity: 57% (124 aa)

LEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRV
.||.|||.||||||||..|.||.||||||||||.|.||.||..||..|..||...|.|.|..........||.|||||.|||.|.|.|||||...|||.|
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLDHFIDYARRELHWECDYQREARCMQKFRQLLKDWPFFYV

PAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLR---------------ELFEFRFMQTDPNWANFLYDAS----SHQVTLLDFGAS
|.|..|.||.|||.|||..|.|.||||||||..||.||.....||||               |.||.||||||||||||.||..    .|.|.|||||||
PHVIDEYCTDRVLTMELMYGFPIDQCQGLSQEIRNYICYNIMRLCLREVEYIFLSTFIIIDFEIFEWRFMQTDPNWANFFYDKHPKTGQHKVELLDFGAS

REFGTEFTDHYIEVVK
||.|..|||||....|
REYGKDFTDHYMQIIK
Kinase ADCK4.AA ABC1 197-313 40 1.7e-60 207.29 In-house 1-123 (123) Show / Hide 
Range on Protein: 197-313
Range on HMM: 1-123/123
Sequence Identity: 40% (50 aa)

EELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAG-----LFAEQSLQALQQELAWECDYRREA
..||  |     ...| |||||||.|||.. |.||..||||.|.||....|..|..|...|.||. ... |     .| .. .. .|.||.||||...||
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

ACAQNFRQLLA--NDPFFRVPAVV
..|...|||..  ..|||.|| ..
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK4.AA ABC1 197-313 35 9.6e-45 152.73 Pfam 1-126 (126) Show / Hide 
Range on Protein: 197-313
Range on HMM: 1-126/126
Sequence Identity: 35% (45 aa)

EELGRDWQAKVASLEEVPFAAASIGQVHQGLLRD-GTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAG-----LFAEQSLQALQQELAWECDYRRE
||||..|  . .. .|.|.|||||.|||.. |.| | |||||.|.||..... .|..|.  ..|  . .. |     .. .. .. ....|.||.|||||
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

AACAQNFRQLLAND---PFFRVPAVV
|. .  ||......   |...|| |.
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK4.AA ABC1-B 211-251 43 1.8e-10 35.1 In-house 14-54 (125) Show / Hide 
Range on Protein: 211-251
Range on HMM: 14-54/125
Sequence Identity: 43% (18 aa)

EEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDV
.. | ||||. |||   | ||..||||.|.| .  ..  |.
DQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDM
Kinase ADCK4.AA ABC1-B 277-313 30 0.063925 3.98 In-house 86-125 (125) Show / Hide 
Range on Protein: 277-313
Range on HMM: 86-125/125
Sequence Identity: 30% (12 aa)

LQQELAWECDYRREAACAQNFRQLLA---NDPFFRVPAVV
.|. |. | |   ||  |   ||...   . .| .|| . 
IQKNLPQELDFYNEARNAEKCRQMFKKFKHFDFLYVPRIH