Gene ADCK3 (Human)

ADCK3

Species: Human
Alias: LOC56997, MGC4849, CABC1, ADCK3, COQ8
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 1q42,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-A

Sequence

Name Sequence Type Origin Length Description Download
ADCK3.AA Protein Sugen Kinome 647 None Fasta, JSON
ADCK3.NA RNA Sugen Kinome 2932 None Fasta, JSON
ADCK3.kin_dom Protein Kinase Domain None 303 None Fasta, JSON

Protein domain

Protein domains of ADCK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK3.AA ABC1-A 331-527 63 2.9e-167 561.99 In-house 1-216 (216) Show / Hide 
Range on Protein: 331-527
Range on HMM: 1-216/216
Sequence Identity: 63% (138 aa)

FEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYV
|||.|||.|||||||.|..|.|||||.||||||||.||.||.||||.|.|||.|.|.|.|..|.||..||||..||||||||.|..|||.|||..|||||
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLDHFIDYARRELHWECDYQREARCMQKFRQLLKDWPFFYV

PEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLR---------------ELFEFHFMQTDPNWSNFFYDPQ----QHKVALLDFGAT
|...||.|...|||.||..|||.||..||||||||.|||||..||||               |.||..||||||||.|||||..    ||||.||||||.
PHVIDEYCTDRVLTMELMYGFPIDQCQGLSQEIRNYICYNIMRLCLREVEYIFLSTFIIIDFEIFEWRFMQTDPNWANFFYDKHPKTGQHKVELLDFGAS

REYDRSFTDLYIQIIR
|||...|||.|.|||.
REYGKDFTDHYMQIIK
Kinase ADCK3.AA ABC1 318-434 45 7.9e-67 228.33 In-house 1-123 (123) Show / Hide 
Range on Protein: 318-434
Range on HMM: 1-123/123
Sequence Identity: 45% (56 aa)

NDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEG-----LFPEHLIDVLRRELALECDYQREA
 ||| || |  . |.|.|||||||.|||.|..|.|..||.|.|.|||...|..|.||...|..|......|     .|.....|....||..|||...||
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

ACARKFRDLLK--GHPFFYVPEIV
..|.|.|.|.|  ..||||||.|.
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK3.AA ABC1 318-434 34 9e-44 149.46 Pfam 1-126 (126) Show / Hide 
Range on Protein: 318-434
Range on HMM: 1-126/126
Sequence Identity: 34% (44 aa)

NDLGPNWRDKLEYFEERPFAAASIGQVHLARMKG-GREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEG-----LFPEHLIDVLRRELALECDYQRE
..|| .|... . |.| |.|||||.||| || |  |.|||.|.|.|||......|..|.  ...  . .. |     .... ..|..|..|. |.|| ||
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

AACARKFRDLLKGH---PFFYVPEIV
|. . .||.....    |..|||...
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK3.AA ABC1-B 318-434 30 4.9e-18 62.56 In-house 1-125 (125) Show / Hide 
Range on Protein: 318-434
Range on HMM: 1-125/125
Sequence Identity: 30% (39 aa)

NDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFP----------EHLIDVLRRELALECD
 ||| |  |  . |.. | ||||. |||.|  ..|..|| |.|.| .  ..  |.. .  ..     . . .||            . | .   |. | |
KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDMMMMELFV----KVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELD

YQREAACARKFRDLLK---GHPFFYVPEIV
   ||  | | | ..|   . .| ||| | 
FYNEARNAEKCRQMFKKFKHFDFLYVPRIH