Gene ADCK2 (Human)

ADCK2

Species: Human
Alias: ADCK2, MGC20727, AARF
External Links: Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP , GeneCards
Annotation: Consensus chromosomal location: 7q34-36,

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-C

Sequence

Name Sequence Type Origin Length Description Download
ADCK2.AA Protein Sugen Kinome 626 None Fasta, JSON
ADCK2.NA RNA Sugen Kinome 2627 None Fasta, JSON
ADCK2.kin_dom Protein Kinase Domain None 307 None Fasta, JSON

Protein domain

Protein domains of ADCK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK2.AA Ciliate-E2c 200-221 36 0.00029 10.95 In-house 1-22 (310) Show / Hide 
Range on Protein: 200-221
Range on HMM: 1-22/310
Sequence Identity: 36% (8 aa)

FENREPVGSGCVAQVYKAYANT
..  ...|||  ..||||| ..
IDRNNILGSGSYGKVYKAYYCE
ABC1 ADCK2.AA ABC1 188-217 30 0.007203 11.93 Pfam 1-30 (126) Show / Hide 
Range on Protein: 188-217
Range on HMM: 1-30/126
Sequence Identity: 30% (9 aa)

QAFGDDWGSILSFENREPVGSGCVAQVYKA
...|..|  | .  ..||....  |||..|
EELGCPWEEIFQEFDEEPIAAASIAQVHRA
Kinase ADCK2.AA ABC1-C 308-614 99 4.1e-298 944.62 In-house 1-307 (307) Show / Hide 
Range on Protein: 308-614
Range on HMM: 1-307/307
Sequence Identity: 99% (304 aa)

VAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
VAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESVP

VSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVAVPSSLCPLRLVLLDAGIVAELQAPDLRN
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|||.|||||||||||||||||||||||
VSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQEAQLQQADICDTLVVTYPSSICPLRLVLLDAGIVAELQAPDLRN

FRAVFMAVVMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPK
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
FRAVFMAVVMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARKNTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPK

LDILEAA
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LDILEAA
Kinase ADCK2.AA ABC1 307-389 29 9.4e-38 131.75 In-house 36-123 (123) Show / Hide 
Range on Protein: 307-389
Range on HMM: 36-123/123
Sequence Identity: 29% (26 aa)

SVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPG---IKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFR--NVKAVKFPTPL
.|||||.|||. .|.|.|...|............   .||..|...|.||.|......|...||.|.|.....|.  .......|...
TVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEARNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK2.AA ABC1 308-389 31 2.3e-20 70.74 Pfam 39-126 (126) Show / Hide 
Range on Protein: 308-389
Range on HMM: 39-126/126
Sequence Identity: 31% (28 aa)

VAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLPGIK---WLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNV---KAVKFPTPL
|||||.|||.  ..  |. .|... ...  ..  .   .. | .||.||.| ... .|.| ||.| |.|. |||.    ..|. |.  
VAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRREAKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK2.AA ABC1-B 307-329 52 0.000314 12.37 In-house 36-58 (125) Show / Hide 
Range on Protein: 307-329
Range on HMM: 36-58/125
Sequence Identity: 52% (12 aa)

SVAVKVLHPGLLAQVHMDLLLMK
.||||| || | .| | |...|.
TVAVKVQHPWLRKQFHYDMMMME