Gene TRA1 (Bakers Yeast)

TRA1

Species: Bakers Yeast
Alias: TRA1
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: Atypical
Family: PIKK
Subfamily: TRRAP

Sequence

Name Sequence Type Origin Length Description Download
TRA1.AA Protein Refseq_NP 1703 Fasta, JSON

Protein domain

Protein domains of TRA1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FAT TRA1.AA FAT 1025-1065 16 1.9e-07 25.15 Pfam 356-408 (408) Show / Hide 
Range on Protein: 1025-1065
Range on HMM: 356-408/408
Sequence Identity: 16% (9 aa)

RRLSEEP------------NNISFASNAISCYLQAAGLYKNSKIRELLCRILW
.......             .| .. .|..|......|...|..|... |.||
EVFQHYQCQPQREEQNYTHMIIQHVVPAVKCFFHSIALSQGSNSRQDTLRLLW
Kinase TRA1.AA PI3Kc 1363-1686 21 9.8e-86 292.05 SMART 1-336 (336) Show / Hide 
Range on Protein: 1363-1686
Range on HMM: 1-336/336
Sequence Identity: 21% (76 aa)

AVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLNA--------
||.... .. |...||.|..||.|| ..|. |.|||. ... .  ||..|. ... .  . .|||.|.....|.|....|..|.||.|.| .        
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDML-VPEIQKNMY

-------AHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQF-EDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEML
       |.........||... ....  .|. .. .||.|.|.. |..  ||.| .|..|....     ..|...|  | ...|..|...|..|   . 
MMIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG

PSRFPYERVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIG----DSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEI-ISWFSNLHRPI
.  . . ..||. |.| .           .| ||||||.... ..|    .| ..| |     .. ||. .. |.. ........|.| ..| .. ....
HIFGHG-PKKPGFKHH-H-----------RERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIK

IENPQLREMVQTNVDLIIRKV------AQLGHLNSTPTVTTQFILDCIGSA
 .. ..|... ..........      . ..|.|.. |..........  .
YLRQRFRLDH-LSDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase TRA1.AA PI3_PI4_kinase 1359-1635 19 3.2e-68 237.74 Pfam 1-300 (300) Show / Hide 
Range on Protein: 1359-1635
Range on HMM: 1-300/300
Sequence Identity: 19% (62 aa)

VHSFAVQYPAVRHSRREERMFQLY-----------------------RLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCK
 ..|...... ...|...|| |..                       ||.|| ..|. ..|||..|.. .. ||..|. ...... . ||.|||. ....
WYPFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYMV

KKGFDPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQF-EDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHV-
|... .. ....| .|.........      ............|..| ..| ..|.. ...  |..| .|..|....   . ..|....  | ...|.| 
KCKHKHFNKEHKMWMKMWPDWWHLM------RMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIMVK

-DKTSGNVFTLEMLPSRFPYERVKPLLKNHDLSLP-PDSPIFHNNEPVPFRLTP------NIQSLI------GDSALEGIFAVNLFTISRALIEPDNELN
 |||.|..|                    .....| .... ||. |.||||.|.      ......      ..|  .| |   .... |||... | . 
DDKTTGHLFHID-----------------FGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCM

TYL-------ALFIRDEIISWFS
..|       .....|....| |
NLLKKAVMRGECMVHDGLPMWRS
Kinase TRA1.AA PIKK 1330-1511 21 1.6e-18 64.36 In-house 1-193 (290) Show / Hide 
Range on Protein: 1330-1511
Range on HMM: 1-193/290
Sequence Identity: 21% (43 aa)

IARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEI
..||.. .  |  .    ....||||||  . . .       .|...|. || .| |. | |. |...|  ..  .  ||.|.. ..  .  . .||.||
RIRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCK--GHEDLRQDQRVMQLFQLMNTCLQKDPECQKRHLHIRTYSVIPMSQRCGLIEWVDNCVTLKEI

HNEFCKKKGFDPDDI-QD---------------FMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFEDFWLFRKQFASQY
 .. |.||.   ... |.                .. .. . . .   .|..   |||.|. .  . .| ...|. | . |.  |..| .|. ....|
YKQWCQKKHIRHEQEAQMNYQTCMYRDWLKQMSYYKHQMQQQCMMYQHWPLH--EKVEVFREQMQN-TPPDMFKKWFWRKFPDPEIWWERRENYTRSY
Kinase TRA1.AA TRRAP 1330-1357 53 1.9e-07 24.15 In-house 1-28 (46) Show / Hide 
Range on Protein: 1330-1357
Range on HMM: 1-28/46
Sequence Identity: 53% (15 aa)

IARFLPTVDFVRGTHSSYRRLMIRGHDG
||||.| |. |       ||| ||||.|
IARFMPRVEIVQKHNTAARRLYIRGHNG
Kinase TRA1.AA FATC 1671-1703 27 6e-06 22.11 Pfam 1-33 (33) Show / Hide 
Range on Protein: 1671-1703
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

TPTVTTQFILDCIGSAVSPRNLARTDVNFMPWF
.|  ..| . . | .|..|.||.. ..  .||.
EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW
Kinase TRA1.AA PIKK 1576-1625 30 0.00019 12.53 In-house 241-290 (290) Show / Hide 
Range on Protein: 1576-1625
Range on HMM: 241-290/290
Sequence Identity: 30% (15 aa)

NEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALF
.|.||||||.|.  . |   .||.|     .. ... .. . | | .  |
PEKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
Kinase TRA1.AA ATR 1577-1625 26 0.00039 9.51 In-house 219-267 (267) Show / Hide 
Range on Protein: 1577-1625
Range on HMM: 219-267/267
Sequence Identity: 26% (13 aa)

EPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALF
| |||||| |..  .|    .|.|   .  | . . .  ...  ..  |
EIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHRDDIMSVWDCF