Gene TPK3 (Bakers Yeast)

TPK3

Species: Bakers Yeast
Alias: TPK3
External Links: Saccharomyces Genome Database Link
Annotation:

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
TPK3.AA Protein Refseq_NP 398 Involved in nutrient control of cell growth and division; Tpk3p [Saccharomyces cerevisiae] Fasta, JSON
TPK3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of TPK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TPK3.AA PKA 88-342 61 7.2e-198 663.63 In-house 1-263 (263) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-263/263
Sequence Identity: 61% (161 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIR-MWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNP
|.|..||||||||||.|.|. |.|..||.|.|||..||.||||||...|...|. ..||||.. |..||||... .|||.|..|||.|| ||||.||.||
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VAKFYAA-EVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTK-PYNKSVDWWSFGVLIYEMLAGYTPFY
.|||||| ...||||||||..||||||||||||.|||||||||||||||.| |.|.||||||.|.|||....| ...||||||..|.|||||||||.|||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

NS--NTMKTYENILNAELKFPPFFHPDA---QDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
..  ..|..|| |.|...|||..|..||    ||.|||...||..|.||..||..|.|||.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase TPK3.AA AGC 88-342 34 8.49999999999e-194 506.76 In-house 1-395 (395) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-395/395
Sequence Identity: 34% (138 aa)

FQILRTLGTGSFGRVHLIRSNH------NGRFYALKTLKKHT-IVKLK--QVEHTNDE------------RRMLSIVS----------HPFIIR-MWGTF
|..|...|.||||.|.| | ..      .|..||.| ||| . ||..|  .||||. |            |..|. ..          ||||.. .. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDSQQ--VFMVMDYIE---------GG-ELFSLLR---KSQRFPNPVAKFYAAE-------VCLALEYLHS-KDIIYRD-LKPENILLDKNGHIKITDFG
|| .   ...||.|..         || |||. |.   |..||. ..|.|||||       ..|||||||| ..||.|| |||||||||..||||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKYVP-----------------------------------------------------DVTYTLCG--TPDYIAPEVVSTKPYNKSVDWWS--FGVLIY
..| ..                                                     | |.|.||  ||.|.|||..    |.|..||||  .|.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLAGYTPFYNSN----------TMKTYENIL------NAELKFP----------PFFHPDAQDLLKKLITRDLSERLGNLQN-----GSEDVKNHPWF
|||.||.|||. |           |.....|.      | ..|||          ..| |.|.||.|||...| ..|||...|     | |..||||||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase TPK3.AA Akt 88-342 45 5.9e-134 430.63 In-house 1-264 (264) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-264/264
Sequence Identity: 45% (121 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFY-ALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNP
|..|. || ||||.| | . . ....| |.| |||  |.. .|||||  ||..|  . ||||. .   ||...  ..||||. |||||..|.. .||. .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

VAKFYAAEVCLALEYLHSKDIIYRD-LKPENILLDKNGHIKITDFGFAK-Y-VPD--VTYTLCGTPDYIAPEVVSTKPYNKSVDWWS-FGVLIYEMLAGY
 |.||.||. ||.|.||||.||||| |||||||.||.|||..|||| .|   . |  .|.|.|||| |.|||. . . . |.||||. .|...|||. | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFYNSNTMKTYENILNAELKFP--PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
 |||| .  . ...|.|...|||  ... |...||...| ..| ..|||.  |. ...|.||||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase TPK3.AA SGK 88-342 42 1.3e-133 415.23 In-house 1-283 (283) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-283/283
Sequence Identity: 42% (120 aa)

FQILRTLGTGSFGRVHLIRSNHN------------------GRFYALKTLKKHTIV-------KLKQVEHTNDER-RMLSIVSHPFIIRMWGTFQDSQQV
|..| ..| ||||.| . .                      . |||.| |.| .|.       | |.. |.  ||   |. ..||||.     ||  .  
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTK
..||||..|||.|. |.. ..|| ..|.|||||. .|||||||.|||||||||||||||  ||...|||| .|      | | | |||| | ||||   .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
|. ..||||. | . |||. |  |||. |.   |.||.| .|..||.. .|| ||.. | ..| ..|||   ......||||.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGT-KRDFMEIKNHPFF
Kinase TPK3.AA AktR 88-342 44 9.3e-128 430.73 In-house 1-268 (268) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-268/268
Sequence Identity: 44% (119 aa)

FQILRTLGTGSFGRVHLIRSN-HNGRFYALKTLKKHTIVKLKQVEHTNDERRMLS-IVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPN
|.... || | ||.| | . .  |...||.| .||..|....| .||  ||  .  ...||||...  .||.  . | .|.|..|||||. |.|...| .
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PVAKFYAAEVCLALEYLHSK-DIIYRDLKPENILLDKNGHIKITDFGFAK--YV---PDVTYTLCGTPDYIAPEVVST-KPYNKSVDWWSFGVLIYEMLA
 .|.||.|...|||||||.. .||||||||||||||..||.|||||| .|   .    ...|..|||| |.|||..   |..|||||||.||..||||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYTPFYNSNTMKTYENILNAE-LKFPPF--FHPDAQDLLK-KLITRDLSERLGNLQNGSEDVKNHPWF
|..|||..|.   ...|.. . .|||.   | . ..||.. ||  ..  .|||   || |..|.||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase TPK3.AA RSK 91-342 40 2.1e-113 383.05 In-house 1-278 (278) Show / Hide 
Range on Protein: 91-342
Range on HMM: 1-278/278
Sequence Identity: 40% (113 aa)

LRTLGTGSFGRVHLIRSN---HNGRFYALKTLKKHTIVKLKQ-VEHTNDERRMLSIVS-HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQR---
|. ||.|..| | | |      .|. || | |||..||. .  ..||  ||. |. .  ||||..   .||. . ....|.|..|||||  |.| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDK---NGHIKITDFGFAKY-VPD---VTYTLCGTPDYIAPEVVS---TKP-YNKSVDWWSFGV
|    |.||.||. ||.|.||...||.|||||||||.|    .||||.|||||.|. ..|    |.| |.| .|.|||..     .  ..|..||||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMLAGYTPFYN---SNTMKTYENILNAE--LKFP--PFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
|.||||.|..||..   .|  .. ..|....  |..|  ..  ..|.||..|. .|| . |||   .. |..|.||||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase TPK3.AA S_TKc 88-342 39 2.6e-111 377.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-231/231
Sequence Identity: 39% (105 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEG--GELFSLLRKSQR---
..|||..| |.||.|.. | .. || .|.| .|          ||.  |...|.   ||.|... ..||| . ..|||.|..|  |.||....| .|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNK-SVDWWSFGVLIYEMLA
   ||  .|.||....|.||||.||. ||.|||||||||||.  ||||.|||.|. .    .|.||||.|.||||.   .|.| ..||||.|...||||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGS--EDVKNHPWF
||.||.  . ......|.           |.| |...|. ..| ..|..  .     .|.|.||||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TPK3.AA PKC 88-342 42 1e-103 337.11 In-house 1-262 (262) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-262/262
Sequence Identity: 42% (111 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS-HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNP
|. |. || |||| | | ..  . ..|| | |||. |..   || |  |.| |.  . |||   .  .||     | || |..|| |     ...||. .
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

VAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK---YVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPF
.|.|||||...|| .||.|.||||||| .|.|||. |||||.||| .|   .  | | | ||||||||||... ..|.||||||.|||| |||.||  ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNG---SEDVKNHPWF
   .     ..|.. .  .|  .. .| ...|.. |.. ..|||  . .   ..|.. || |
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase TPK3.AA RSK 88-342 40 3.8e-100 339.02 In-house 1-271 (271) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-271/271
Sequence Identity: 40% (111 aa)

FQILRTLGTGSFG---RVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFP
. ... .|.|||.    .. ..   ... || | .|| |..   .   .  || .|. . ||||..    ||| ..|.|.||  .||.||  | |   |.
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

NPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKN----GHIKITDFGFAKYVPD---VTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEML
   .|||.||. ||.|||||..|..|||||||||.|      |||||.|||||| . |    ..| |.|  |.||||.. . . ...|||||||| ||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

AGYTPFYNSNTMKTYENILNAELKF-------PPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
.|.|||.| .   . ..|... |         . |  . |.||| .. .||   |||.  || |..|.||||
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase TPK3.AA PKG 88-342 44 9.1e-100 337.75 In-house 1-260 (260) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-260/260
Sequence Identity: 44% (116 aa)

FQILRTLGTGSFGRVHLIRSNHNG-RFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNP
..|. ||| | |||| |...||   | .||| .||. ||. .| ||   |.. .   . .||.|.. || |.  |.| |    |||| . ||. ..| ..
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

VAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFY
 ..||.| |  |..|||.| ||||||||||..||..| .|. |||||| .     |.| |||| |.|||..  |    |||.|. |.|..| | | .|| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

NSNTMKTYENILN--AELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
 |. ||||  ||     . || .    ||.. |||     .||||...|| .|.| | ||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase TPK3.AA Pkinase 88-342 33 1.1e-99 342.21 Pfam 1-293 (293) Show / Hide 
Range on Protein: 88-342
Range on HMM: 1-293/293
Sequence Identity: 33% (100 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTN-DERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGG----ELFSLLR--KS
..|.|..| ||||.| . .   .|. .|.|..||... . |...|..  | ...  ..||.|.|....|.|.. . |||.| |||    .||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QRF--PNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHI----KITDFGFAK---YVPDVTYTLCGTPDYIAPEVVS-TKPYNKSVDWWSFG
 .|  .  ..|||. ... .|||.||. ||.|||||||||.|.||||    ||.|||.||   | .....|.||||.|.||||.   ..| ..||.||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

VLIYEMLAGYTPFYNS------NTMKTYENILNAELKFPPFFH---------------------PDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWF
...|||| |..||...      . |. ...|. ..|.|. .                       ....|..|.....| ..|..      |....||||
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase TPK3.AA MAST 88-234 40 6.8e-62 187.59 In-house 1-150 (337) Show / Hide 
Range on Protein: 88-234
Range on HMM: 1-150/337
Sequence Identity: 40% (60 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQD--SQQVFMVMDYIEGGELFSLLRKSQ-RFP
| ... .. | .|.| | .    . ..|.|.... .. . .||.. . ||  |.... ||.  |  .||    . ..|||.| |||  .||||    ..|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

NPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAK
   ||.| ||  |.||||||..|. |||||.|.|.|.|||||.||||..|
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase TPK3.AA MAST 244-342 41 7.2e-47 140.83 In-house 229-337 (337) Show / Hide 
Range on Protein: 244-342
Range on HMM: 229-337/337
Sequence Identity: 41% (46 aa)

CGTPDYIAPEVVSTKP-YNKSVDWWSFGVLIYEMLAGYTPFYNSNTMK-TYENILN--AELKFPPF--------FHPDAQDLLKKLITRDLSERLGNLQN
|||||||||||   .. |.|.||||| |. .|| |.|..||  ..  . . .||.|   |. .|.         . |.|||| ||| . . ..|||    
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGAN--

GSEDVKNHPWF
|....|.|| |
GADEIKQHPFF
Kinase TPK3.AA Pkinase_Tyr 88-301 26 1.4e-18 63.56 Pfam 1-225 (270) Show / Hide 
Range on Protein: 88-301
Range on HMM: 1-225/270
Sequence Identity: 26% (64 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFY----------ALKTLKKHTIVKL-KQVEHTNDERRMLSIV-SHPFIIRMWGTFQ-DSQQ--VFMVMDYIEGGE
 .....|| |.||.|..      |. .          | |.|| ..  .  .. .  . | ....   .|| |.|. |    ....  ...|| | ..| 
ITFGKKLGEGAFGEVYK------GTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGD

LFSLLRK----SQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV-PDVTY-TLCG--------TPDYIAPEVVSTK
| . |||     |... .    ...... ..|||.|| .| |||   |.|...|...||.||| |... .| .| .  |        .    |||. ...
LLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYG

PYNKSVDWWSFGVLIYEMLA-GYTPFYNSNTMKTYENILNAELK
 ..   | ||||||..|..  | .|        ||... |.|..
KFTTKSDVWSFGVLMWEIFTYGEQP--------TYPGMSNEEVY
Kinase TPK3.AA TyrKc 88-326 21 3.7e-17 54.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 88-326
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIV--SHPFIIRMWGTFQDS-------QQVFMVMDYIEGGELFSLLR
 . ...|| | ||.|.. . .   .  | |.||...   ..   .   | |... .  .|| |.|. |   ..       .....|| | ..| | . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMR---EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KSQR-FPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV-------TYTLC----GTPD-----YIAPEVVSTKPYN
|... ....    ..  ..   |||||| .| |||   |.|...|...||.||| .... |         |       |. .       |||.  .. ..
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KSVDWWSFGVLIYEMLA-GYTPFYN-----SNTMKTYENILNA-ELKFPPF--------FHPDAQDLLKKLITR---------DLSERL
   | |||||...|..  | .| ..      .    .|.. .   .. ||          ...  .. |.   .         .. |..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TPK3.AA S_TK_X 343-398 20 6.5e-05 18.64 SMART 1-79 (79) Show / Hide 
Range on Protein: 343-398
Range on HMM: 1-79/79
Sequence Identity: 20% (16 aa)

NEVIWEKLLA--RYIETPYEPPIQQ---GQGDTSQFD-RYPE-----EEFNY----GIQGED--------PYMDLMKEF
 .. |.||..  . || |. |.|..   ...|||.||  ..|       ..     ... ..        |. .. . |
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF