Gene STE7 (Bakers Yeast)
STE7
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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STE7.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 276 | Kinase domain by global Sugen HMM | Fasta, JSON |
STE7.AA | Protein | Refseq_NP | 515 | `Serine/threonine/tyrosine protein kinase of the pheromone pathway, homologous to MAP kinase kinase family; Ste7p [Saccharomyces cerevisiae]` | Fasta, JSON |
Protein domains of STE7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | STE7.AA | STE7-Unclassified | 191-466 | 44 | 1.2e-172 | 579.88 | In-house | 1-301 (301) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-301/301 Sequence Identity: 44% (136 aa) LVQLGKIGAGNSGTVVKALHVP------DSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILS |..|...|.|..|||||.||.. |.||.|.|.||...|......|..|||.......||..|...|||||.......|.|.|||.||||||.... LERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLHKCQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKID VYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSI--ADTFVGTSTYMSPERIQGN--- .||....||.. ...|..|....||||.|..||..|.....||||||||.|.|.|||||.|.|||||...|.|.. |.|.||...|||||||||. IYKKMYERGPI--RGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPH --VYSIKGDVWSLGLMIIELVTGEFPLG------GHNDTPD----GILDLLQRIVNEPSPRLPKDR---IYSKEMTDFVNRCCIKNERERSSIHELLH-H .||.|.|.|||||.|.|..||..|.. ..|.... ....||..|||.|.||||.|. |.|||..||...||.|..|||..||.||. | RPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEH DLI ..| PWI |
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Kinase | STE7.AA | STE7 | 191-466 | 40 | 3e-152 | 512.11 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-288/288 Sequence Identity: 40% (121 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFV |...|..|.||.|.| |..|.|..|| | |.|....|.... .|...|| .... .....|..||||.|... .. | | ||| |.|.|||.....|... LEHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHKCNDCPYIVQFYGAFYTEGDDC-IWICMEYMDGGCLDKFYKRVKKVY QRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSI--ADTFVGTSTYMSPERIQG--NVYSIKGD || . ||....| . |||. |..||..|....||||||.||||.|.||.||.||||||....|..|. | ||||...||.||||.| . |... | -RG-I--KKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGNKQHYDVRSD VWSLGLMI-IELVTGEFPLG----------GHNDTPD---GILDLLQRIVNE-PSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLH-HDLI |||||... ||..||..|.. .|.... .|...|. |||| |.|||| ..|.|..||||.|..|...|| ..|.|.. |. | VWSLGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP---KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI |
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Kinase | STE7.AA | STE | 191-466 | 28 | 5.7e-100 | 338.42 | In-house | 1-359 (359) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-359/359 Sequence Identity: 28% (105 aa) LVQLGKIGAGNSGTVVKALHV------PDSKI---------VAKKTIPVEQNNS---------------TIINQLVRELSIVKNVKP-HENIITFYGAYY . ..||| |..|||.||... . .. .| | ...|..|. ....|. .|..| |. .. |.||...||.|. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF N----QHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSK-KTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSK . .. ..|. | ||| | ||||.|. .. .. . ... ...|.| |..|.. .| || .. . .||||||||.|.|. .|||||||.. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG KLINSIA--------------D----TFVGTSTYMSPERIQG------NVYSIKGDVWSLGLMIIELVTGEFPLGGHNDT------PDGI-----LDLLQ .|..|.| . ||||| .|.||.||. . |..| |.||||..|||..||. |. ... |... ...| QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL- RIVNEPSPRLPKD-----------------RIYSKEMTDFVNRCCIKNERERSSIHELLH--HDLI |||.|.|.|| . . .|.|. ||.|.|..|. ..| . ..||. | | CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | STE7.AA | Pkinase | 191-466 | 29 | 5.4e-94 | 323.38 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-293/293 Sequence Identity: 29% (92 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVR--ELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCG----SLDKILS .. ..|||.|..|.| |. |. ..|||| |.|... ..| ...| |..| |.. |.||...|..... ...| . ||| ..| .| ..| YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIS VYKRFVQRGTVSSKKTWF--NELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQI----KLCDFGVSK---KLINSIADTFVGTSTYMSPER . .....| | .. ...| .| ||...... .|||||.||.|.||...|.| |.||||..| || ..||.||. ||.|| T-----------WRHGCFYFSEWECKFYMYQILRGLEYCHSM-GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV IQ-GNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYS---------------------KEMTDFVNRCCIKNERE |. |. |. | |.||.|....|...|..| ||. ..|. .| .|.|.. .|.|. |. .. .|. ||...|. |. . IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK RSSIHELLHHDLI | .....|.|. . RPTAEQILQHPWF |
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Kinase | STE7.AA | S_TKc | 191-466 | 27 | 4.7e-71 | 243.29 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-231/231 Sequence Identity: 27% (78 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDC--GSLDKILSVYKR | ||| | |.| |. |. . .||| | |. ... ||..| |. |.||...|..... ... . ||| | |.| ... ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGR FVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSI-KGDV | .|.| .. ...| ....|... .. .|||||.||.|.|... .||.||||....| .||.|| ||.|| . |. | |. HGLR-------FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDW WSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLH-------HDLI ||.| ...|...|. | . ....|. |.|. ||...|. |. ..| .. |.|. | . WSCGCILYEMLCGYPPFP-------QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | STE7.AA | MEK5 | 191-466 | 39 | 9.6e-65 | 221.4 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-254/254 Sequence Identity: 39% (109 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFV . .| || ||| || ||| ||.| | | .. . |.. || |. || ||||.. . | | | |. | |||| .|.. IRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDI-TLELQKQIMSELEILYKCD-SPYIIGFYGAFF---VENRISICTEFMDGGSLD----MYRCIP QRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSL | . ... . || |. . ||.|||.||||.|.| .||||||||||| .|.|||. |..|| || |||| |. | | ||||| -------------EHILGRMTVAIVKGLNYLW-NLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITRTYIGTNAYMAPERISGDQYGIHSDVWSL GLMIIELVTGEFPLGGHNDTP--DGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI |....|. || || . . ||| ||.| .|||| |. .|. .|.|.| | ..| ..|. | | GIFFMEMATGRFPYPQIQRDQGELMPIQLLQCIVDEHPPRLPVDK-FSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI |
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Kinase | STE7.AA | STE20 | 191-466 | 33 | 9.4e-64 | 218.11 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-288/288 Sequence Identity: 33% (102 aa) LVQLGKIGAGNSGTVVKALHVPDSKI----VAKKTIPVEQNNS--TIINQLVRELSIVKNVKPHENIITFYGAYYNQHIN-NEIIILMEYSDCGSLDKIL | ||| |..|.| || |.| .. || | ...|. . .. .. | || |. | |.||...||.|. . . .|. |.||| . ||| |. YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM S---VYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLIN----SIA---DTFVGTSTYMSP . . .. . | . .|| |. | ..|| |||.| .. .||||||| |.|....|..||.||||. .|.. ... .||||| .|.| KHCMKCGKNHK-G------HPMNEEQIAYICREVLQGLDYLHSN-HIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAP ERIQG-----NVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIV--NEPSPRLPK--DRIYSKEMTDFVNRCCIKNERERSSIHELLHHD | ||. . | | |.|||| ..||...|| |. .. | . . .| ..|.|.| . . .|.| |||..| |. .| . .||.| EVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPY--FDMHP---MRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHP LI | FI |
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Kinase | STE7.AA | MEK1 | 191-404 | 43 | 3.4e-62 | 211.23 | In-house | 1-196 (297) | Show / Hide |
Range on Protein: 191-404 Range on HMM: 1-196/297 Sequence Identity: 43% (93 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVK-PHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRF . ..| .|.|| | |.|. | . |.|.| | .| . | ||..||| .. . |. |. ||||.|. ..|| | ||| | |||| .| .| FEKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPA-IRNQIIRELQVLHECNSPY--IVGFYGAFYS---DGEISICMEYMDGGSLDQVLKKAGRI VQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWS | . |.. || || | ..||.|||.||||.|.||.| ||||||||| .|| |.| |||| ||||||.|| |... |.|| P-------------EKILGKVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYTVQSDIWS LGLMIIELVTGEFPL .|| ..|.. | .|. MGLSLVEMAIGRYPI |
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Kinase | STE7.AA | MEK4 | 298-466 | 36 | 2.8e-59 | 192.06 | In-house | 101-275 (275) | Show / Hide |
Range on Protein: 298-466 Range on HMM: 101-275/275 Sequence Identity: 36% (65 aa) KKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTF-VGTSTYMSPERIQG--NV--YSIKGDVWSLGL .|. .| . .|.. . . |..| .. ||||||.||||.|.. .| .||||||.. | .||| | .| || ||||. | | |. |||||| QKSRIPENIMGHITVCTVDALNYLKETHKIIHRDVKPSNILLDRHGCVKLCDFGICGQLVDSIAKTHDAGCRPYMAPERIDPEQNMDGYDIRSDVWSLGI MIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRI---YSKEMTDFVNRCCIKNERERSSIHELLHHDLI ..|. ||.|| . || . ..| .. .|. .|.| .| ||..| .|.| | .|....| . .|. .. . TMYEVATGKFPYRKWNDAS--VFDQICMVVKGDPPILHHDHHDMHYSMPMCRFINTCLTKDRNHRPKYDNLKKFPFY |
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Kinase | STE7.AA | MEK3 | 307-466 | 42 | 3.1e-56 | 189.76 | In-house | 104-264 (264) | Show / Hide |
Range on Protein: 307-466 Range on HMM: 104-264/264 Sequence Identity: 42% (70 aa) ISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTF-VGTSTYMSPERI--QGNV--YSIKGDVWSLGLMIIELVTGE ..||| . .| .. | |.||||.|||||||| .||.|.||||.| |..|.| | | || |||| ..| |..| |||||| .||. .| LGKIAMSIVSALHYMHEQLKVIHRDVKPSNVLINHHGQVKMCDFGISGYLVDSMAKTIDAGCKPYMAPERIDPEMNQKGYDVKSDVWSLGITMIEMAIGR FPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI .| . . |. .| ||.|.||... .| .. ||.|.| || || | ||. | . YPYDNWHT----PFQQLKQVVEEPPPQLPMEKGFSPDCQDFINQCLKKNYMERPSYPELMEHPFM |
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Kinase | STE7.AA | ULK | 191-466 | 25 | 3.2e-53 | 183.13 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-324/324 Sequence Identity: 25% (85 aa) LVQLGKIGAGNSG-TVVKALHVPD---SKIVAKKTIP---VEQNNST-----IINQLVRELSIVKNVK--PHEN--IITFYGAYYNQHINNEIIILMEYS . ..| | | .| |. .. . ..|| | |. .... ....| .| .|.| | |.| |. .| ..... | | | ||| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNH-NNIYIIMEYC DCGSLDKILSVYKR----FVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSK------------GQIKLCDFGVSKKLIN ..| |.... .|. .| ..| . .. . .||. .|. . .||||||||.| ||. . |..|..||| .|.. | NGGDLEQYIKKNKKLPETE--------EKKRLSEQEAIQFFKQICNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN -----SIADTFV------GTSTYMSPERIQGN-----VYSIKGDVWSLGLMIIELVTGEFP--LGGHNDTPDGILDLLQR------IVNEPSPRLP---K . |.| || ||.|. .||. |..| |.|||| .. |...|. | ||. ..| .|.. ... . | | NNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPK DRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI | . |.|. |. |. ...|..| |..|...| .. DPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | STE7.AA | ULK | 191-466 | 25 | 1.7e-52 | 180.74 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 191-466 Range on HMM: 1-329/329 Sequence Identity: 25% (87 aa) LVQLGKIGAGNSGTVVKALHVPD----SKIVAKKTIP-----VEQNNST---IINQLVRELSIVKNVK-------PHENIITFYGAYYNQHINNEIIILM . ..| | |.| |. .. . ..|| | |. ..|... ....| .| | | | |.||. .| ..... | | | | YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNH-NNIYIIM EYSDCGSLDKILSVYKR-----FVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSK------------GQIKLCDFGVSK || . | |..... .|. .| ..| . .. . |||. .|. . .||||||||.|.||. . |..|..||| .| EYCNGGDLEQYIKKNKKLPEDTE--------EKKRLSEQEAIQFFKQILNGFKELHKH-NIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK KLINS-----IADTFV------GTSTYMSPERIQGN-----VYSIKGDVWSLGLMIIELVTGEFP--LGGHNDTPDGILDLLQRI-------VNEPSPRL .. |. .. |.| || ||.|. .||. |. | |.|||| .. |...|. | ||. . |. | .. .. .. HVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQF P---KDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI | .| . |.|. |. |. ...|..| |..||..| .. PKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | STE7.AA | Pkinase_Tyr | 191-406 | 25 | 5e-20 | 68.45 | Pfam | 1-218 (270) | Show / Hide |
Range on Protein: 191-406 Range on HMM: 1-218/270 Sequence Identity: 25% (59 aa) LVQLGKIGAGNSGTVVKALHV----PDSKIVAKKTIPVEQNNSTI--INQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILS .. . |.|.|. |.|.|. . || |.. |. . . . ||..| |. |.||. .||. . | |.|.| ||| .|.|.. | ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR VYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTST-------YMSPERIQ . . | .. .. .... . .|...| .. ..||||. |.|.......| |||| .. . . . ... |.|| |. KHR---------EDKQPLTMKDLLQMCWQIAKGMEYLESK-NCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECIN GNVYSIKGDVWSLGLMIIELVT-GEFP-LGG .....| |||| | . |..| || | | YGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG |
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Kinase | STE7.AA | TyrKc | 191-465 | 19 | 2.4e-17 | 57.87 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 191-465 Range on HMM: 1-280/280 Sequence Identity: 19% (58 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNV-KPHENIITFYGAYYNQHIN----NEIIILMEYSDCGSLDKILSV .. . |.| |. |.|.|. || |.. . . . ||..| ... . |.||. .||. | | . |.||| . |.|.. | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK YKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKL-----------INSI----ADTFVGTSTY ... .. . .... . .| ..| .. ..||||. |.|.......| .||| |... . .. HRPK------------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW MSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGH---NDTPDGILDLLQRIVNEPSPRLPKDRI------YSKEMTDFVNRCCIKNERERSSIHELL |.|| |. .....| |||| | .. |. | . . . ...... . .. |.. ..|| . .|. . .| . |. MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI- HHDL |... HECF |
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Kinase | STE7.AA | MEK1 | 414-466 | 47 | 1.5e-14 | 45.68 | In-house | 246-297 (297) | Show / Hide |
Range on Protein: 414-466 Range on HMM: 246-297/297 Sequence Identity: 47% (25 aa) ILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLI | ..|. ||||| |.||. |..|.|. |||. | ||| || . .|. | | IFEMLDYIVNEPPPKLPH-RVFSEEFQDFVDKCLIKNPDERADLKQLMVHTFI |
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Kinase | STE7.AA | MEK4 | 191-260 | 32 | 2.6e-10 | 29.69 | In-house | 1-75 (275) | Show / Hide |
Range on Protein: 191-260 Range on HMM: 1-75/275 Sequence Identity: 32% (24 aa) LVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNN-----STIINQLVRELSIVKNVKPHENIITFYGAYYN | ||.||.|. ||| | .| . ||.| | | . . .| .|. |. . .|. |||| .. LQDLGEIGNGAFGTVNKMWHKESGKIMAVKRIRCNNVDPDDAFHKEQKRLLMEHDVVMKSENCPYIVKFYGACFK |