Gene STE11 (Bakers Yeast)

STE11

Species: Bakers Yeast
Alias: STE11
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
STE11.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 298 Kinase domain by global Sugen HMM Fasta, JSON
STE11.AA Protein Refseq_NP 717 involved in the mating signalling pathway; Ste11p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of STE11.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SAM_2 STE11.AA SAM_2 17-82 25 5.2e-18 64.66 Pfam 1-71 (71) Show / Hide 
Range on Protein: 17-82
Range on HMM: 1-71/71
Sequence Identity: 25% (18 aa)

EKTNDLPFVQLFLEEIGC-TQYLDSFIQCNLVTEEEI-KYLDKDIL--I-ALGVNKIGDRLKILRKSKSFQ
... ... |. .|..||.  || |.| |... ..| . .... | |  . ..|... |.|.||..| ....
VHYWTFEDVCEWLRSIGMCCQYKDNFRQHGITGFEHLYAHMTHDDLAMKNRMGITNVGHRKKIWNKIQRMK
SAM STE11.AA SAM 17-84 23 1.1e-13 52.75 SMART 1-67 (67) Show / Hide 
Range on Protein: 17-84
Range on HMM: 1-67/67
Sequence Identity: 23% (16 aa)

EKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRD
 . .. . |. .|| ||. || | |..... ... .. .. . |  .|....|.|.|||.. .... .
VD-WTPEDVCDWLESIGMCQYKDNFRKNGIDGMHLLQLTSHEDLKEMGITNPGHRKKILKAIQKMKDQ
Sam7 STE11.AA sam7 20-82 21 1.8e-13 45.76 In-house 1-70 (70) Show / Hide 
Range on Protein: 20-82
Range on HMM: 1-70/70
Sequence Identity: 21% (15 aa)

NDLPFVQLFLEEIGC---TQYLDSFIQCNL----VTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQ
 .   |. .||.||.    || |.| ...     .. ......... | ..|....| |.||... . ..
WTFEDVCEWLEWIGMENFQQYCDNFRDHGIDDWVTDGDHLCHMTEEDLMEMGITRPGHRKKIWNHIQQMR
SAM_1 STE11.AA SAM_1 18-76 26 4.5e-09 35.14 Pfam 1-60 (66) Show / Hide 
Range on Protein: 18-76
Range on HMM: 1-60/66
Sequence Identity: 26% (16 aa)

KTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIA-LGVNKIGDRLKILR
  ..   |. .||.||. || |.| . .... ...  .... | . .||...|.|.||..
DYWHFEDVCEWLESIGMQQYIDHFMRAGYIDMDCLLQMTWEDLMKHMGVTLPGHRKKIMY
Kinase STE11.AA STE11-Unclassified 415-712 42 6.00000000001e-179 600.78 In-house 1-308 (308) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-308/308
Sequence Identity: 42% (146 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHE
| ||..||.||||.||..||..|||.|||||.||...|.                    |||.....               |....|.||..||.|.|.
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNS--------------------QQEDMQKE---------------MIQSIQKEMKVLKQLNHK

NIVTYYGAS--QEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISK----------
|||.|||..  ......|||.||.||||..||||.||.|.|..|...|.|||.|.||||...||||||||||||||..|..|.||||..|          
NIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNKYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTV

-----------KLS-PLNKKQNKRASLQGSVF---WMSPEVVK---QTATTAKADIWSTGCVVIEMFTGKHPFPDFSQ---MQAIFKIG-TNTTPEIPS-
           |.. ..|..||...|.||...   ||.|||.|   ||....|.||||.||.||||.|||||......   |.||.||. .|..|.||. 
RMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEH

----------WATSEGKNFLRKAFELDYQYRPSALELLQHPWL
          |...|.|.||||.|..|...||.| .|||||..
LSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQLLQHPFI
Kinase STE11.AA STE11 415-712 42 1.7e-163 549.44 In-house 1-303 (303) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-303/303
Sequence Identity: 42% (140 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHE
| ||..||.|.||.||..|| .|||||||||.||.||| .                 |.|......              .||..|.|.|..|.| |.|.
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMK----------------EDQEKEYQS--------------HKMHKAIQEEIKLMKHLNHK

NIVTYYGASQ---EGGNLNIFLEYVPGGSVSSMLN-NYGP--FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC-VKITDFGISKKLS-P
||| |||...   . ...|||.||.||||.||||. ..||  |.|..| ..|.||| |..|||...||||||||||||.| .|. .|..|||..|.|.  
NIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWI

LNKKQNKRA------SLQGSVF--------WMSPEVVKQTA---TTAKADIWSTGCVVIEMFTGKHPFPDFSQ--MQAIFKIG-T-NTTPEIPS------
.....|...      |..|...        ||.|||.||.     ..|||||| ||.||||.|||.|......  |.|.|||| . ...|.||.      
CTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPIS

WATSEGKNFLRKAFELDYQYRPSALELLQHPWL
|.. |...|||. || |...||.| .|||||..
WISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase STE11.AA STE 416-712 28 4.6e-112 378.6 In-house 1-359 (359) Show / Hide 
Range on Protein: 416-712
Range on HMM: 1-359/359
Sequence Identity: 28% (113 aa)

LKG-ACIGSGSFGSVYLGMNAH---------------TGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVD
..|  .||.|.||.||..|| .               |||.||.||....|.|  . .           |    | |. . .        ..|.. . ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-E-----------N----Q-EN-Q-E--------LENKNHEEMQ

ALQHEMNLLKELH--HENIVTYYGASQEGG-------NLNIFLEYVPGGSVSSMLN-NYGPFE-------------ESLITNFTRQILIG-VAYLHKKNI
 ...|....|...  |.|||.|||.   .|       .|.|..||..|||...... .||...             ||.|  ..|||| |  .|||...|
QILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI

IHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQ-------------NKRASLQGSVFWMSPEVVKQ------TATTAKADIWSTGCVVIEMFTGKHP
||||||.||||.     ||..|||....|.. . ..              || .. |.  ||.|||..|         ..|.|||| ||..||| |||.|
IHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP

FPDFSQMQAIFKIGTN---------------TTPEIPS-------------------WATSEGKNFLRKAFELDYQYRPSALELLQ--HPWL
. |.. |.|.| | .|               . | .|.                     ..| |.|..| .. |.. ||.| .||.  ||..
WHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase STE11.AA S_TKc 415-712 27 9.7e-96 325.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-231/231
Sequence Identity: 27% (86 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHE
. ..  ||.|.||.||.. . .||...|.|..                                                    . .. |...||. ||.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------------------------------EHIRREIQILKK-HHP

NIVTYYGASQEGGNLNIFLEYVPG--GSVSSMLNNYGP------FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSP
|||..|.. |. ..| ...||..|  |.. ... ..|.      | |  .  ...||. ...|.|...|||||.| .|||.|   ..||.|||....|  
NIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--

LNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALEL
         .. |. ..|.|||.    ...|.|.|| ||...||..|. |||   |||..||.            ..|.|.|.|| .. | . ||.| |.
--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EA

LQ-------HPWL
||       |||.
LQDEWDIKCHPWF
Kinase STE11.AA Pkinase 415-712 26 1.9e-84 291.65 Pfam 1-293 (293) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-293/293
Sequence Identity: 26% (89 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVP-----TDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLK
. .| .|||||||.||....  ||.. |||... .... ...     .                                              |  ..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL---------------------------------------------SEIQIMK

ELHHENIVTYYGASQEGGNLNIFLEYVPGG----SVSSMLN--NYGPF--EESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCV----KITD
.|.|.|||..|.. ...... . .||..||    . ....   ..|.|  .|  . .. .||| |..|.|...|||||.| .||||| .| .    ||.|
RLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICD

FGISKKLSPLNKKQNKRASLQGSVFWMSPEVVK-QTATTAKADIWSTGCVVIEMFTGKHPFPDF------SQMQAIFKIGTNTTPEIPSWAT--------
||..|...  . ..    .. |. ..|.|||.. ..  . |.|.|| ||...||..|. |||.       .||| |..|.   ...  .|          
FGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFR

------------SEGKNFLRKAFELDYQYRPSALELLQHPWL
            .|.| |... ...| . ||.| ..|||||.
HWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase STE11.AA STE20 415-712 28 1.9e-76 260.31 In-house 1-288 (288) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-288/288
Sequence Identity: 28% (95 aa)

WLKGACIGSGSFGSVYLGMNAHTGEL----MAVKQVEIKN-NNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLK
. .  .||.||.|.||.. . .|||.     |.|...... .|                                          ..... .| | . .|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNE-----------------------------------------QDEWEDIQKEISIMK

ELHHENIVTYYGASQEG----GNLNIFLEYVPGGSVSSMLN---NYG------PFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKIT
...|.|||.|||. . .     .| |  ||  |||.. ...   . |      |..|. |   .|..| | .|||...|||||||..|||.. .| ||..
QCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLA

DFGISKKLSPLNKKQN---KRASLQGSVFWMSPEVVKQ-----TATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIG--TNTTP--EI--PSWAT
||| . .|..... .    || .. |. .||.|||...        . |.|||| |   ||| .|. |. |.. |.|.|.|   .| .|  .   |.  .
DFGVCAQLTKHGR-DTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWS

SEGKNFLRKAFELDYQYRPSALELLQHPWL
.| ..|. |  . |.. ||.| .||.||..
PEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase STE11.AA MEKK2 495-712 47 2e-75 256.91 In-house 42-262 (262) Show / Hide 
Range on Protein: 495-712
Range on HMM: 42-262/262
Sequence Identity: 47% (104 aa)

RKMVDALQHEMNLLKELHHENIVTYYGASQEGG--NLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC
|| |.||. |..||| | || || |||  .. .   | ||.||.|||||   |  ||.  |.    .||||| |..||| . |.|||||||||| |  | 
RKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGN

VKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGT-NTTPEIPSWATSEGKNFLRK
||. ||| ||.|  .  .     |  |  .||||||.       |||.|| || |.|| | | |. ..  | ||||| | .| |..|.    ....||..
VKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKR

AFELDYQYRPSALELLQHPWL
 |    | |||| |||.| . 
CFVEIKQDRPSAEELLRHHFV
Kinase STE11.AA MEKK15 501-712 41 1.6e-72 247.22 In-house 48-264 (264) Show / Hide 
Range on Protein: 501-712
Range on HMM: 48-264/264
Sequence Identity: 41% (91 aa)

LQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGI
|| |..||| |.| |||.| | . |   .|||...|||||.||..| .|| .|     .|.||| ||.|||  ...||||||.|...   | .|. ||| 
LQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGC

SKKLSPL--NKKQ-NKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTN--TTPEIPSWATSEGKNFLRKAFEL
 |.|.    |. . .   |..|  .|| |||.. |    |.|||| || | || |.| |. |  .| |.| ||.     |..|     . ..| |     
AKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTR

DYQYRPSALELLQHPWL
| . ||.|..||.||..
DQHERPTASQLLKHPFI
Kinase STE11.AA ASK 421-712 36 8.1e-69 227.97 In-house 2-254 (254) Show / Hide 
Range on Protein: 421-712
Range on HMM: 2-254/254
Sequence Identity: 36% (108 aa)

IGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYY
.| |..| || | . ||   .|.| .. ....                                             |  |. |..| |.|.|.||| | 
LGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR--------------------------------------------YVQPLHEEIALHKQLRHRNIVQYL

GASQEGGNLNIFLEYVPGGSVSSMLN-NYGPFE--ESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDI-KGCVKITDFGISKKLSPLNKKQNKRAS
|.  |.| . ||.| |||||.|..|   .||..  |. .. .|.||| |. ||| ..|.|||||| |.|.    | ||| ||| .|.|  .|   .   .
GCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINPCTE---T

LQGSVFWMSPEVVKQTAT--TAKADIWSTGCVVIEMFTGKHPFPDFSQMQ-AIFKIGT-NTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL
 .| . .| |||. |      . ||||| || ..|| ||| || .. . | |.||.|   . ||||.  . | |||....|| | . |.|| .||| |.|
FTGTLQYMAPEVIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase STE11.AA Dicty2 504-712 38 2.9e-68 233.12 In-house 53-264 (264) Show / Hide 
Range on Protein: 504-712
Range on HMM: 53-264/264
Sequence Identity: 38% (82 aa)

EMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGC---VKITDFGI
|..||| | |.|||.|..  .   .|.|.|||. .|| |  ....|.| |||.... .|.| | .||| . .||||||.|||||   |    .| .||| 
EIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGV

SKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTA--TTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQ
  ... . .  ..|..  |  .|| |||        . . |||| || .||..||  |  |  .| | |..  .  | .|   ..| |.||   |  |  
ATHID-Y-SDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTIIELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPN

YRPSALELLQHPWL
 |..| .||.|||.
QRMTAKQLLHHPWI
Kinase STE11.AA ULK 487-712 25 2.4e-49 170.27 In-house 37-324 (324) Show / Hide 
Range on Protein: 487-712
Range on HMM: 37-324/324
Sequence Identity: 25% (75 aa)

PKTNQNIHRKMVD------ALQHEMNLLKELH---HEN--IVTYYGASQEG--GNLNIFLEYVPGGSVSSMLNNYGP---------FEESLITNFTRQIL
.| ..|.  .. .       |. | ...|.|.   |.|  || .|  ...    |. |..|| .||  .. ......         ..|. . .| .||.
DKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQIC

IGVAYLHKKNIIHRDIKGANILIDIK------------GCVKITDFGISKKLSPLNKKQNKRASLQ------GSVFWMSPEVVKQT-----ATTAKADIW
 |  .|||.|||||||| .||||  .            |..||.||| .|..   |. |... ..       |.   |.|.....       ...|.|||
NGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIW

STGCVVIEMFTGKHPF--PDFSQMQ-------------AIFKIGTNTTPEIPS---WATSEGKNFLRKAFELDYQYRPSALELLQHPWL
| ||.  || .|| ||  . |.. .              |.   ..  . .|.      .| |...|. .. |   | |  |...|||.
SLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase STE11.AA STE-Unique 529-712 27 3.7e-49 169.63 In-house 369-616 (616) Show / Hide 
Range on Protein: 529-712
Range on HMM: 369-616/616
Sequence Identity: 27% (67 aa)

LNIFLEYVPGGSVSSMLNNYGP---------FEESLITNFTRQILIGVAYLHKKN--IIHRDIKGANILIDIKG-----CVKITDFGISKKLSPL-----
..||.|| ..|...  ... |.         |.|...  .|.||| |  ||| .   |||||.| .||... .|      ||| |||......|      
VWIFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFEKD

------------------------------NKKQNKRASLQGSVFWMSPEVVKQT-----ATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQA---IFKI
                              |     . .. |  ..|.|||.           .|.|||| ||....| .| .|.  .. |||   .  .
NNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIH

GTNTTP-----EIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWL
..   |     .||.  . |   |..|..|..   |||| .||.|.||
IHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase STE11.AA Pkinase_Tyr 499-684 29 9.6e-34 114.91 Pfam 48-244 (270) Show / Hide 
Range on Protein: 499-684
Range on HMM: 48-244/270
Sequence Identity: 29% (59 aa)

DALQHEMNLLKEL-HHENIVTYYGASQ-EGGN--LNIFLEYVPGGSVSSMLNNY----GPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIK
... .|....|.| ||.||| .||.   .|.   . | .||.|.|.  . | .     .|.  . . .. .||  | .||. ||.||||.   |.|.. .
EDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTEN

GCVKITDFGISKKLSPLNKKQ-NKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHP-FPDFSQMQAIFKI-GTNTTPEIPSWATSE
..|||.||| .. .         || .    ..||.||. .    | | |.|| | .  |.|| |. | .|. |  . . .|   .   ..|  .. |
NVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDE
Kinase STE11.AA TyrKc 415-712 23 3.2e-25 91.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 415-712
Range on HMM: 1-280/280
Sequence Identity: 23% (78 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKEL--H
  .|  .|.| || ||.|.                                             ..| ||   |. .. .   . .. .|......|  |
ITLGKKLGEGAFGEVYKGTWK-------------------------------------------IQV-AV---KMLKEDA---REDFMREARIMCKLGGH

HENIVTYYGASQEG-------GNLNIFLEYVPGGSVSSMLNNYGP-FEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKL
|.|||  ||.  ..       . | | .||.|.|.  . | ...| .  .   .|  ||  | .|||.||.||||.   |.|.. ...|||.||| |...
HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDI

SPL----NKKQNKRA----SLQ--GSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFT-GKHPFPD-----FSQMQAIFKIGTNTTPEIPSW--------
         |. .|.    .      . ||.||. .    | | |.|| | .  |.|| |. | |.      |  ..| .. .   ...|          
YDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVC

ATSEGKNFLRKAFELDYQYRPSALELLQHPWL
...|  .  ..  . |   ||.  |.  |  .
CPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase STE11.AA MEKK15 415-452 47 3.7e-09 29.4 In-house 1-37 (264) Show / Hide 
Range on Protein: 415-452
Range on HMM: 1-37/264
Sequence Identity: 47% (18 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNN
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WKKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDEID
Kinase STE11.AA MEKK2 415-452 42 8.7e-09 27.98 In-house 1-38 (262) Show / Hide 
Range on Protein: 415-452
Range on HMM: 1-38/262
Sequence Identity: 42% (16 aa)

WLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNN
| .|  .| | || ||.   . ||  .|||||.. ..|
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDN
Kinase STE11.AA ULK 415-452 28 5.4e-07 20.93 In-house 1-45 (324) Show / Hide 
Range on Protein: 415-452
Range on HMM: 1-45/324
Sequence Identity: 28% (13 aa)

WLKGACIGSGSFG-SVYLGMNAHT---GELMAVKQVE---IKNNN
. .  |.|.||||  || | |  |   ... |.|...   .....
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKK
Kinase STE11.AA Dicty2 415-453 38 3e-06 18.1 In-house 1-42 (264) Show / Hide 
Range on Protein: 415-453
Range on HMM: 1-42/264
Sequence Identity: 38% (16 aa)

WLKG-ACIGSGSFGSVYLGMNAHTGELMAVKQVE--IKNNNI
 . |   || | || || | .. ||.  | ||..   | ..|
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKI
Kinase STE11.AA STE-Unique 497-528 35 1.7e-05 14.82 In-house 44-85 (616) Show / Hide 
Range on Protein: 497-528
Range on HMM: 44-85/616
Sequence Identity: 35% (15 aa)

MVDALQHEMNLLKELHHENIVTYYGASQEG----------GN
.|  .. |  ..| |||.|||.|||.  .|          ||
LVNMIISEIEIMKCLHHQNIVKYYGHWLWGGCDSFQSLEEGN
Kinase STE11.AA STE-Unique 416-450 31 0.003791 6.36 In-house 1-35 (616) Show / Hide 
Range on Protein: 416-450
Range on HMM: 1-35/616
Sequence Identity: 31% (11 aa)

LKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKN
.    || |||| |..  |  ..  .|.| ...|.
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQ
Kinase STE11.AA Pkinase_Tyr 421-432 58 1.380009 2.61 Pfam 7-18 (270) Show / Hide 
Range on Protein: 421-432
Range on HMM: 7-18/270
Sequence Identity: 58% (7 aa)

IGSGSFGSVYLG
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LGEGAFGEVYKG