Gene SSK2 (Bakers Yeast)

SSK2

Species: Bakers Yeast
Alias: SSK2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
SSK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 293 Kinase domain by global Sugen HMM Fasta, JSON
SSK2.AA Protein Refseq_NP 1579 Suppressor of Sensor Kinase (SLN1); Ssk2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of SSK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SSK2.AA STE11-Unclassified 1266-1558 44 1.2e-186 626.38 In-house 1-308 (308) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-308/308
Sequence Identity: 44% (140 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSK----SMQKI-FPLIKEEMSVLEILNHPNIVSYYGVE--VHRDKVNIFMEYCEGGSLAALLEH
|||..|||.|.||.||.......||..|||.|.|.|..    .|||. ...|..||.||. |||.|||.|||.|  .|.|..||||||..|||....|..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

GRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMM
....||||...|| |.||||||||..||.|||.|..|||.||.|..|..|||.||.|....||...||||.|.|       |...........|.. .|.
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFD-------HYKICQHINSQQNHCKSMQ

GTPM---YMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDN---EWAIMYHVAAGHTPQFPTKDE---------VSSAGMKFLERCLIQNP
|||.   .|||| |..||..|.....|.|||||.|.||.||..||.|..|   .||||..|.....||.|....         .|.....||..|. ..|
GTPYQPFWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDP

SKRASAVELLMDPWI
.||..| .||..|.|
KKRPTANQLLQHPFI
Kinase SSK2.AA STE11 1266-1558 41 1.2e-157 529.99 In-house 1-303 (303) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-303/303
Sequence Identity: 41% (133 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSM----------QKIFPLIKEEMSVLEILNHPNIVSYYGVEVH---RDKVNIFMEYCEGGSL
|||...|| |.||.||.....|.||..|||.| ||....|          .|....|.||..... |||.||| |||...|   .|.||||||||.||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

AALLEHGR---IEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGV-IKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVK
...|.|..   . ||||...|| |.||||.|||. ||.|||.|..|||||..|. .|..|||.||..|...|. ..||...| .       ..|. . . 
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQN-H-------CKSMTGTPY

NNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDN-EWAIMYHVAAGHTPQFPTKDEVS------SAGMKFLERCLIQ
|      .||||||.|||| |......|.  ..|.|||||.|.||.||..||.|.|. ..|.|.....||.|. |  ...|       ... || .|. .
N------SMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEH

NPSKRASAVELLMDPWI
.|.||..| .||..|.|
DPKKRPTANQLLQHPFI
Kinase SSK2.AA STE 1266-1558 25 2.2e-97 329.81 In-house 1-359 (359) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-359/359
Sequence Identity: 25% (101 aa)

WQKRNFIGGGTFGRVYSAVDLD---------------NGEILAVKEINIQDSKSM-------------QKIFPLIKEEMSVLEILN--HPNIVSYYGVEV
|..  .|| |.|| || |.. .               .||| |.|..|.......             ....  |..|....  .|  ||||| ||| ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

H-------RDKVNIFMEYCEGGSLAALLEH--GRIED------------EMVTQVYTLQLLEG-LAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAK
.       .|...|.|||..||||  ...|  |. ..            | .  ... |.|.| |.|||. .|.|||.|| ||||     .| .||| ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNEN---------ALLDMMGTPMYMAPESITG-STT--KGKLGADDVWSLGCVVLEMITGRRPWA
......... . .                      || .             . ||| .|||| |.. ...  ||     |.|||||...||.||. ||.
QLTDSMANI-Q-S----------------------NN-IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWH

NLDNE---WAIM--YHVAA---------GHTPQFPT-----------------KDEVSSAGMKFLERCLIQNPSKRASAVELLM--DPWI
.. .    ..|.  ||...         |. |..|.                 ....|.    |...||. .|.||..| .||    |.|
DMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase SSK2.AA S_TKc 1266-1558 27 3.3e-88 300.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-231/231
Sequence Identity: 27% (86 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEG--GSLAALLEHGRI--
... . || |.||.|| ... . |.| |.|.|.             |. |...|.  .||||| .|.| .. |.. ..||||.|  |.|  .... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----EDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDM
     .| ... |. |....|.|.|. ||.|||.||||||||   .||  ||| |...                                         .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------------------------------------TTF

MGTPMYMAPESITGSTTKGKLG-ADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLM--
 ||| ||||| .      |  . . |.||.||.. ||..|. |.     . . |...              |. .  |...||  .|.|| .| |.|   
CGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----DPWI
     .||.
WDIKCHPWF
Kinase SSK2.AA Pkinase 1266-1558 29 3.6e-69 240.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-293/293
Sequence Identity: 29% (99 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQK-----IFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGG----SLAALL
...   || |.||.|| ... ..|.| |||.|. .. || ..     .      | ...  ||||||| .|..   .|.. . |||||||    .|....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

E---HGRI-EDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVI----KYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVK
.   ||..  .| . . | .|.|.||.|.|. ||.|||.||||||.| ||.|    |  ||| ||..                                 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------------------------Y-

NNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANL------DNEWAIMYHVAAGHTPQFPTKDEVS--------------
||.  . .  ||| ||||| |   . ..   . |.||.||.. ||..|| |. .       |  . |     .    ..|.....|              
NNS--MTTFCGTPWYMAPEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH

---SAGMKFLERCLIQNPSKRASAVELLMDPWI
   ... .|...|| ..|.|| .| ..| .||.
NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase SSK2.AA CAMK 1271-1558 19 8.5e-57 181.21 In-house 1-425 (425) Show / Hide 
Range on Protein: 1271-1558
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

FIGGGTFGRVYSAVDL-DNG-----------EILAVKEINIQDSKS------------------------MQKIFPLIKEEMSVLEI-------LNHPNI
 .| |.|| |. ...  ..|           .  |.| |. .  |.                         .|    .. |....         |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSYYGVEVH-------------------RDKVNIFM---EYCEGG----S-LAALLEHGRIE--------------DEMVTQVYTLQLLEGLAYLHESGI
.. | |                      .... ..|   |||.||      .  . |||.                .|  .. |  |......|.|. .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDVKPENILLDFN-----------------GVIKYVDFGAA--KKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENA---------LLDMM
|||| |||||||| |                 . || .||| |  ..  .| . .....  |    .                  .         . .. 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN------------------QWTTPTEGQKMKTFC

GTPMYMA-PESITGST-----------TKGKLGADDVWSLGCVVLEMITGRRPWA---------------NLDNEW-AIMYHVAAGHTPQFPT-------
||| ||| || . |..            ..   . |.||.|..   | .|. |.                |. . .  ||        |.|..       
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGP

--KDEVSSA--------GMKFLERCLIQNPSKRASAVELLMDPWI
   |..|           . .. ..|  .|.||... . | .||.
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase SSK2.AA ULK 1266-1558 25 1.9e-54 187.18 In-house 1-324 (324) Show / Hide 
Range on Protein: 1266-1558
Range on HMM: 1-324/324
Sequence Identity: 25% (88 aa)

WQKRNFIGGGTFG-RVYSAVDLDN---GEILAVKEIN---IQDSKSM---QKIFPLIKEEMSVLEILN---HPN--IVSYYGVEVHR--DKVNIFMEYCE
..... .| |.||  || . . ..   ... |.| |.   ....|..   | .  |.| | ... .|.   |||  || .| .      . . |.||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLAALLE---------HGRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFN------------GVIKYVDFGAAKKIANNGTRLASMNK
|| |  ...          ...  |. .. .  |...|. .||. .|.||| ||.|||.  .            ||.|  ||| ||.. ||.     .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IENADGEHEDVTHVSDSKAVKNNENALLDMM---GTPMYMAPESITGSTTKGKLG-A-DDVWSLGCVVLEMITGRRP---WANLDNEWAIMYHVAAG---
. |   |                           |||.||||. . |   . . . .  |.|||||.  ||..|. |   |.| .... |. ..  |   
CVN---E-----------------------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQ

------HTPQFPTKD---EVSSAGMKFLERCLIQNPSKRASAVELLMDPWI
         ||| ..    .|.    .. |.|. ....| |  |..  ||.
QIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase SSK2.AA Ciliate-E2 1272-1558 20 5.7e-53 180.17 In-house 7-365 (365) Show / Hide 
Range on Protein: 1272-1558
Range on HMM: 7-365/365
Sequence Identity: 20% (82 aa)

IGGGTFGRVYSAVDLDNGE-----------------------ILAVKEINIQDSKSMQKIFPLIK---------EEMSVLEILNHPNIVSYYGVEV--HR
|| |.|| || . .  ...                       | |.| .. .. ... ..  ...         .|...||.||||||. .| .     .
IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDD

DKVNIFMEYCEGGSLAALLEHGRIE-----------DEMVTQVYTLQLLE---------------GLAYLHESG-IVHRDVKPENILLDFNGVIKYVDFG
... . ||||.||.|  .... ..            .|   . .. |.|.               .| |||. . |.||| ||||||.     || .|||
NNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFG

AAKKIANN--------------------------GTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMM-----GTPMYMAPESITGST------
 .||. ..                          .  .                               . ..|     |||.||||| . |        
LSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD--Q------------------------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQK

TKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTK----------------DEVSSAGMKFLER----CLIQNPSKRAS-AVEL
 ||   . |.||||..  ||..|..|.          .        .|| .                ...|  .. .. .    .|  .|.|| . . ..
QKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI

LMDPWI
|  ||.
LNHPWF
Kinase SSK2.AA MEKK4 1266-1420 44 5.7e-48 162.61 In-house 1-154 (271) Show / Hide 
Range on Protein: 1266-1420
Range on HMM: 1-154/271
Sequence Identity: 44% (69 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEM
||  . || | || ||.... | .|..|.||. .|      |    | .|.  .| . ||| | |||||||| .. ||||||  | |  . . |   .| 
WQRGDHIGEGQFGKVYTCMNMDTHEVMAMKEMRFQ--RNDHKAIKNIADEIKIFEGIKHPNLVRYYGVEVHREEMYIFMEYCSQGTLERVCHLGGNMQEH

VTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNG-T
..  || ||| .  |||. ||||||.|| || ||  .|.|  ||| . |. |.  |
MIRQYTKQLLRAVNYLHQHGIVHRDIKPANIFLDKCTVLKLGDFGCSVKLQNHSQT
Kinase SSK2.AA MEKK15 1266-1419 38 9.5e-40 138.37 In-house 1-155 (264) Show / Hide 
Range on Protein: 1266-1419
Range on HMM: 1-155/264
Sequence Identity: 38% (60 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDS--KSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIED
|.| | .| | .| ||  .  . | ..||| ......  .  .. .  ..||. .|  | | |||.| || ..   |||||..  |||.....      |
WKKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLD

EMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNG
|||   || |.|.| .||||  .||||.|  |..|   |.|| .||| ||...  |
EMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQG
Kinase SSK2.AA ASK 1272-1416 43 9.5e-39 126.39 In-house 2-146 (254) Show / Hide 
Range on Protein: 1272-1416
Range on HMM: 2-146/254
Sequence Identity: 43% (65 aa)

IGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEH--GRIE-DEMVTQ
.| ||.| || . |...   .|.|||. .||.  |   ||  ||... . | | ||| | |   . . . ||||   ||||.|||.   | .. .|   .
LGKGTYGIVYAGRDMHTQVRIAIKEIPERDSRYVQ---PLH-EEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMN

VYTLQLLEGLAYLHESGIVHRDVKPENILLD-FNGVIKYVDFGAAKKIA
 || |.|||| ||||  |||||.| .|.|.  . ||.|  ||| .|..|
FYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLA
Kinase SSK2.AA MEKK2 1266-1415 41 1.4e-36 127.85 In-house 1-153 (262) Show / Hide 
Range on Protein: 1266-1415
Range on HMM: 1-153/262
Sequence Identity: 41% (64 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQ-DSKSMQKIFPLIKEEMSVLEILNHPNIVSYYGVEVHRD--KVNIFMEYCEGGSLAALLEHGRIE
|..   .| | |||||   | | |  |||| .... |.   .|    .. |. .|  | |. || |||    .    . |||||  |||.   |      
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGAL

DEMVTQVYTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKI
 | ||  || |.|||..|||.  |||||.|  ||| |  | .|  ||||.|..
TETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRL
Kinase SSK2.AA MEKK4 1458-1558 42 1.4e-26 88.3 In-house 163-271 (271) Show / Hide 
Range on Protein: 1458-1558
Range on HMM: 163-271/271
Sequence Identity: 42% (47 aa)

MGTPMYMAPESITGSTTK-------GKLGADDVWSLGCVVLEMITGRRPWA---NLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRA
|||. ||||| .|            |   | |.||||||| ||.|| |||.     | . .||| |  || |. |  |  |  |  |.  ||   | .| 
MGTAAYMAPEVYTYTEKDETTGSYSGHGRAADIWSLGCVVVEMMTGKRPWHGQTQYDHNFQIMYKVGMGHYPHIP--DKMSPEGKDFFDHCLEHDPKDRW

SAVELLMDPWI
 |.|||  . .
TANELLDHTFC
Kinase SSK2.AA ASK 1459-1558 38 9.3e-22 68.98 In-house 157-254 (254) Show / Hide 
Range on Protein: 1459-1558
Range on HMM: 157-254/254
Sequence Identity: 38% (39 aa)

GTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHT-PQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPW
||  ||||| .     .|   . |.||.|| ..|| ||. |.  |..  | |..|    . |. |.  |.| .  .|. ||   .| ||||| .|| ||.
GTLQYMAPE-VIDQGQRGYGKPADIWSFGCTMVEMATGKPPFHELGEPQAAMFKVGMYKKHPEIPE--ELSAECKNFILRCFEPDPCKRASAQDLLQDPF

I
.
L
Kinase SSK2.AA MEKK15 1452-1558 37 1.8e-20 70.93 In-house 162-264 (264) Show / Hide 
Range on Protein: 1452-1558
Range on HMM: 162-264/264
Sequence Identity: 37% (41 aa)

NALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAA-GHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAV
. |  | ||| .|||| |  .   |     |.||.|| | || |.. |||..|   |. |  |  .  || | |   |    .| . ||      |..|.
DMLKSMRGTPYWMAPEVIMET---GYGRKSDIWSIGCTVFEMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVK--FSEDARMFVRMCLTRDQHERPTAS

ELLMDPWI
.||  |.|
QLLKHPFI
Kinase SSK2.AA MEKK2 1459-1558 39 1.7e-16 56.35 In-house 168-262 (262) Show / Hide 
Range on Protein: 1459-1558
Range on HMM: 168-262/262
Sequence Identity: 39% (39 aa)

GTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYHVAAGHTPQFPTKDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWI
||| .|.|| | |    |     ||||.|| | ||.| . |||. .   ||         || |  ..||  .  ||.|| ..    | || |||   ..
GTPYWMSPEVING---EGYGRKADVWSIGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLP--QHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase SSK2.AA TyrKc 1266-1561 22 4e-15 21.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 1266-1561
Range on HMM: 1-280/280
Sequence Identity: 22% (74 aa)

WQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEIL--NHPNIVSYYGVEVHR-------DKVNIFMEYCEGGSLAALL
 ..   .| | ||.|| ..     .  ||| ..             . .|....  |  .|||||  ||| ..        . . | |||...|.|   |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

EHGRIEDEMVTQV-YTLQLLEGLAYLHESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANN---GTRLASMNKIENADGEHEDVTHVS---DSK---A
   | .  | . . . .|  .| .|||. ...|||    |.|.. |...|  ||| ...| .    |              | .|. ...   ..|    
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------------ESKDYYRKKEHKGGKTMLP

VKNNENALLDMMGTPMYMAPESITGS--TTKGKLGADDVWSLGCVVLEMIT-GRRPWAN-----LDNEWAIMYHVAAGHTPQFPTKDE------VSSAGM
..               ||||.|  .  |||      |||| | .  |. | |  |. .     ..|.  .. .| .|. .  |  |.       ...  
IR--------------WMAPECINYGKFTTKS-----DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQ-EVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY

KFLERCLIQNPSKRASAVELLMDPWIVQI
.  ..|   .|..| .  |.     . ..
QIMKQCWHEDPEDRPTFSEI-----HECF
Kinase SSK2.AA Pkinase_Tyr 1272-1391 25 2.9e-11 38.75 Pfam 7-137 (270) Show / Hide 
Range on Protein: 1272-1391
Range on HMM: 7-137/270
Sequence Identity: 25% (34 aa)

IGGGTFGRVYSAVDL----DNGEILAVKEINIQDSKSMQKI--FPLIKEEMSVLEIL-NHPNIVSYYGVEV-HRDK--VNIFMEYCEGGSLAALLEH---
.| | ||.|| ..      ...   ||| ..    ..|..        .|....  | .|||||..||| . ...   . | |||...|.|   |     
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHRE

-GRIEDEMVTQVYTLQLLEGLAYLHESGIVHRDV
 ..  .      . .|  .|..||.. ...|||.
DKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase SSK2.AA Pkinase_Tyr 1482-1506 40 0.016735 9.1 Pfam 196-222 (270) Show / Hide 
Range on Protein: 1482-1506
Range on HMM: 196-222/270
Sequence Identity: 40% (11 aa)

DVWSLGCVVLEMIT-GRRP-WANLDNE
|||| | .  |..| |. | .....||
DVWSFGVLMWEIFTYGEQPTYPGMSNE