Gene SLT2 (Bakers Yeast)
SLT2
Sequence
Protein domains of SLT2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | SLT2.AA | ERK | 23-318 | 60 | 3e-224 | 751.26 | In-house | 1-307 (307) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-307/307 Sequence Identity: 60% (185 aa) FQLIKEIGHGAYGIVCSARFAE---AAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQII .|.||.|||||||.||||.. | ......|||||..|.|.....||| |||.||||||.||.||.||.|......|. ..|..|..|||||.|.|||| YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPE-QYNDIYCVEELMETDLHQII KSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR----GYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAID .| |.|.|.|.|.|.|||||||||||||.|.||||||.|.||| .|.|||||||||| .|.||...|..|.|||||||||||||||||.| ||||.| NSQQELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD VWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTP-PDETLRRIGSKNVQDYIHQLGF--IPKVPFVNLYPNAN--SQALDLLEQMLAFDPQKRITVD .||.|||.||.||.||.|.|||||.|.|.|.|..||| ..|.|..|.|.|...||..|.. .|..|. |..|||| .||.||||.||.|||.|||||. IWSCGCIFAEMLGRKPLFPGKDYVHQINRIFQIIGTPHSEEDLQYICSENAWKYIKNLPNPVRPPKPWENIFPNANCNPQAIDLLEKMLVFDPDKRITVE EALEHPYL |.|||||. ECLEHPYF |
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Kinase | SLT2.AA | MAPK | 23-318 | 51 | 8.99999999999e-191 | 640.06 | In-house | 1-328 (328) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-328/328 Sequence Identity: 51% (168 aa) FQLIKEIGHGAYGIVCSARFAE----AAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVF-----YPDGSINGLYLYEELMEC .|..| ||.||||.||||. . . ....|||||. ..|.....||| .||.||||||..|.|| .|.|. . .. .. | .|...||||. YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET DMHQIIKSGQPLTDAHYQSFTYQILCG--LKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQ----------FLTEYVATRWYRAP |.||||||.|||.| | |.|.||||.| |||||||.|.||||||.|.||| .|.||||||||||. . .. | ..|||||||||||| DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP EIMLS--YQGYTKAIDVWSAGCILAEFLG-GKPIFKGKDYVNQLNQILQVLGTPPDETLRRIG-SKNVQDYIHQL---GFIPKVPFVNLYPN----ANSQ ||||. ...||||.|.||.|||.||.|. .||.|.||||..|.|.|..|||||..| ...|. |... .||..| ||.|. ...|| ||.| EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQ ALDLLEQMLAFDPQKRITVDEALEHPYL |.||||.||.|||.|||||.|||.|||. AIDLLEKMLVFDPDKRITVEEALQHPYF |
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Kinase | SLT2.AA | CMGC | 23-318 | 27 | 5e-140 | 463.32 | In-house | 1-513 (513) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-513/513 Sequence Identity: 27% (144 aa) FQLIKEIGHGAYGIVCSARFAE------------AAEDTTVAIKKVTNVFSKTLLCK----------RSLRELKLLRHFR----------------GHKN .. || ||.|.||.|...| . . |||||. |.| .. .| |.|||.|.|.|.. |.| YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN ITCLYDMDIVFYPDGS-----------INGLYLYEELMECDMHQIIKSGQ---------PLTDAH------------YQSFT------YQILCGLK--YI | .|||. .||. | ||| |.|..| .|.||. | ||.. | ..|. ||||.||| |. IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC HSAD--VLHRDLKPGNLLVNADCQL--------------------KICDFGLARGYSENPVE-----------------NSQFLTEYVATRWYRAPEIML ||.. ..|||||| |.|.| .|.| ||||||||| |.... . .....|.||.|||||||||.| HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL SY---------QGYTKAIDVWSAGCILAEFLGG--------KPIFK-----------GKDYVNQLNQILQVLGTP----------------PDETLRRIG .. ..||..||.||.|||.|| . | ||.|. ||....||..| .||||| ..| .|. GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK --------------------SKNVQDYIHQ---LGFIPKVPFVNLYPN-----------------------------------ANSQALDLLEQMLAFDP |. .. ||.. .. .|. |. ||.|. ...||.|||..|| .|| LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP QKRITVDEALEHPYL .||||...||.|||. DKRITAEQALQHPYF |
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Kinase | SLT2.AA | p38 | 23-318 | 45 | 6.4e-126 | 424.63 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-289/289 Sequence Identity: 45% (136 aa) FQLIKEIGHGAYGIVCSARFAEAAED-TTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYP----DGSINGLYLYEELMECDMHQ .| .. .| |||| ||.|. .. . ||||| | ... || |||.||.| | | |. || | || | ... |. ..|. | .. YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLD---VFTPPAHSMNDFQDVYMVTHFMGADLNN IIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVW |.|. . |.| | | |||| ||||||||.. ||||||.|. || || |.| |||||| . . .|.||||||||||||||. ||...|.| IMKCQR-LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR-------HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIW SAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPY | |||.|| . |.. |.|.|...||..|..|.|||..| . .| |.. || . .|. | .....|| ||.|||| || || ||||. ||..||| SVGCIMAELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPY L . F |
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Kinase | SLT2.AA | ERK5 | 23-318 | 49 | 2.2e-124 | 419.53 | In-house | 1-295 (295) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-295/295 Sequence Identity: 49% (148 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG .. | .|| ||||.||||| . |||||. | | . || .||||.||||| | || . |. | . . | .||| |.|||| | YKIIEKIGNGAYGVVCSARRRKNGQQ--VAIKKIPNAFDVVTNAKRTFRELKILRHFR-HDNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSN QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSE-NPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGC ||.| | | |||| ||||.|||.|.|||||| ||||| | ||| |||.||| . | . |.|||||||||||||.|.| . ||.|||||| || QPFTLEHIRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGC ILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQ-LGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL |. | .. . .| || |..||. |..|||.|| .. ... |. |. . . ... .|| | |||||| .|| |.| .|||| .|| ||.| IFGEMIARRQMFPGKNYIHQLQLIMMVLGMPPPHMIQAVSADHVYNYFQKNFPNRQPKDWEKVYPKADRQALDLLARMLRFEPSERITVNKALQHPFL |
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Kinase | SLT2.AA | ERK1 | 23-318 | 52 | 1e-115 | 390.74 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-289/289 Sequence Identity: 52% (155 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG . .. ||.||||.|||| . . . |||||. | |.| |||.|.| |. | || . |. | .. .|. .||| |. ...|. YTNLQYIGEGAYGMVCSA--YDTVHKQRVAIKKIS-PFEHQTYCQRTLREIKILTRFK-HENIINIQDI-IRADTIEQMRDVYIVQCLMETDLYKLLKT- QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCI |.| | | |||| |||||||| |||||||| |||.| | |||||||||| .. . |||||||||||||||||| .||||.||.|| ||| QHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLAR-IADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI LAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL ||| | .||| || |. ||| || ||| | . |. | . |.. | . ||||. |.|.| |.|||||..||.| |.|||||.||| |||| LAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINEKARNYLQSLPHKPKVPWARLFPKADSKALDLLDKMLTFNPHKRITVEEALAHPYL |
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Kinase | SLT2.AA | ERK7 | 23-318 | 41 | 5e-109 | 368.52 | In-house | 1-292 (292) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-292/292 Sequence Identity: 41% (123 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMECDMHQIIKSG ....| .| |||||| | . . .||.||. | | || .|. |..| || |.. |. | .|| | || |.| .|. | YEIRKRLGKGAYGIVWKAYDKRTKQ--VVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLIN---VIRADNDRD-IYLVFEFMETDLHAVIRKG QPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENP--VENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAG . | | | |. ||.| .||.||..|.|||||| |.|....| .|.||||||| .. . |. . |||||||||||||||.|. . |||..| || | NILKDIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIG CILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYL |||.| | |||.| | .||...||.... | | . |||. ..|.. .. .. ...|.. .|.||| ..|.| |.||.|...||.||| CILGEMLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV |
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Kinase | SLT2.AA | nmo | 23-318 | 42 | 5.4e-96 | 295.68 | In-house | 1-292 (292) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-292/292 Sequence Identity: 42% (128 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDG-SINGLYLYEELMECDMHQIIKS | . ||.||.|.| | . . ||.||. ||| . ||| ||||.| |. | | | .||. |. . .| ||| |.|.|| | IQPDRPIGYGAFGVVWS--VTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFK-HDN--VLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVS GQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGC |.|. | . | |||| ||||.|||..||||.||||||||..| |||||||||| . ..|. .|. | | .||||||.. . || |.|.|| || PQHLSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQ---DQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGC ILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPN---ANSQALDLLEQMLAFDPQKRITVDEALEHPYL | || || . .|. . ..||. | ..|||| | .. . . . |... . |. | .|| .|| |||.||| . .||.|||| IFAELLGRRILFQAQSPIQQLQMITDLLGTPSMEDMKYACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATHEAVHLLCRMLHFDPDKRISCKDALAHPYL |
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Kinase | SLT2.AA | S_TKc | 23-318 | 28 | 2.9e-93 | 317.08 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-231/231 Sequence Identity: 28% (89 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLYEELMEC---DMHQII ......||.||.| |. .| . . ||||.. .. .||...|.. .|.|| |||. . ||. |... |....| YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYI KSGQP------LTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIMLSYQGYTK- |. .. .. | ....|||.|.|.|.|| ..|||||| |.|.. ..||||||||| . | .. |.||.|||.. ||.| KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL----GYGKC AIDVWSAGCILAEFLGGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLEQMLAFDPQKRITVDEA ..|.|| ||||.|.| |.| | |........| ..|.|.....| .||.||.|. || KCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA LE-------HPYL |. ||.. LQDEWDIKCHPWF |
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Kinase | SLT2.AA | CDK | 23-318 | 31 | 3.4e-92 | 295.26 | In-house | 1-284 (284) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-284/284 Sequence Identity: 31% (102 aa) FQLIKEIGHGAYGIVCSARFAEAA---EDTTVAIKKVTNVF-----SKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGS-----INGLYLYEE .. ...|| |.||.| || . . ||.||. |. . ..|| .||.. |.|| .|.| . .| . .| ||. | YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE LMECDMHQIIKSGQPLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQ-----LKICDFGLARGYSEN---PVENSQFLTEYVATRWYRAP |. | .... .....|.| || |.|| ..|||||| |.|.| . . ||| |||||| .. . . |... .| | |.||||| YMDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRAP EIMLSYQGYT--KAIDVWSAGCILAEFLG---GKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLE |. | . |. .||.||.|||.||.. .||.| |. .|| | ...||| ... . . .|| |||. ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGV--TKLPDY------------------------DLLN QMLAFDPQKRITVDEALEHPYL .||..||.|||. ..||.|||. KMLCYDPKKRISAEQALQHPYF |
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Kinase | SLT2.AA | Pkinase | 23-318 | 26 | 6.7e-84 | 289.83 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-293/293 Sequence Identity: 26% (86 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLR--ELKLLRHFRGHKNITCLYDMDIVFYPDGSINGLYLY--EELMEC----- ..... || |..| |. .. . .||.|.. . | ... .| |....... .|.|| |||. . ..| |..|. YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVM DMHQIIK--SGQPL--TDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQL----KICDFGLARGYSENPVENSQFLTEYVATRWYRAPEIML | . .|. .. .. .. . ... ||||.||.|.|| ..|||||| |.|.. .... ||||||||. .. |.. .| .. |.||.|||. . DLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIR SYQGYTKAIDVWSAGCILAEFLGGKPIFKGK----DYVNQLNQILQVLGTPPDET-----------LRRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQ ..|.|....|.||.||||.|.| |.|.|.|. . ..|. | ...|.|... .|. . . . .|... GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-H--------------F-HWTF-HNWSEE ALDLLEQMLAFDPQKRITVDEALEHPYL ..|... .|..||.||.| ...|.||.. CKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | SLT2.AA | MAPK-Unclassified | 23-176 | 45 | 1.5e-58 | 200.86 | In-house | 1-157 (575) | Show / Hide |
Range on Protein: 23-176 Range on HMM: 1-157/575 Sequence Identity: 45% (74 aa) FQLIKEIGHGAYGIVCSARFAEAAE-DTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNITCLYDMDIVFYPDGSIN----GLYLYEELMEC---D ..| || ||||.|| |. . ||||||. .| .|||.|||. .||. | || . |. ||... | .|. ..|. | YEYQKNIGSGAYGQVC--RAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLN-HPNIIQIQDI---FYNKELHNQEFDDIYIVMDYMQTSLFD MHQIIKSGQ-PLTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR .|||||| | .. . | | |.|||| ||||.||| ..|||||| |||.| || ..|||||..| LHQIIKSNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSR |
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Kinase | SLT2.AA | MAPK-Unclassified | 189-318 | 33 | 2.2e-58 | 200.25 | In-house | 405-575 (575) | Show / Hide |
Range on Protein: 189-318 Range on HMM: 405-575/575 Sequence Identity: 33% (57 aa) LTEYVATRWYRAPEIMLSYQGYTKAIDVWSAGCILAEFLGG-----------KPIFKGKD--------------------YVNQLNQILQVLGTPPDETL .|.||.|||||||||||| . |....| ||.|||.|| . .|.|.|.| .. |.. |. .||.|| | . MTQYVVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDC RRIGSKNVQDYIHQLGFIPKVPFVNLYPNANS----------QALDLLEQMLAFDPQKRITVDEALEHPYL ..|.. .. .|| .. . |.| |.. ... ...|.. .||.|.|.|||| |.|||||| NFITCDSARKYIQSFKCKTPVHFTDLMFCKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF |
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Kinase | SLT2.AA | TyrKc | 23-318 | 22 | 1.2e-13 | -2.24 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 23-318 Range on HMM: 1-280/280 Sequence Identity: 22% (73 aa) FQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHF-RGHKNITCLYDMDIVFYPDG----SINGLYLYEELMEC-DMH .|.|..|.||.|.|. .. ..||.|.. . . .||....... |.|| .|| | .| .| |.. |.|. | . ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLY---GVCTQQGRNFMYIEPLMIVMEYMPHGDLK QIIKSGQP-LTDAHYQSFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSEN-------PVENSQF--LTEY-VATRWYRAPEIML . ... .| |. .. || .|| || |.|| . |||| | ||... . ||.||||.| . . .. . . . ||. ||| . DYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI- SYQGYTKAIDVWSAGCILAEFL-GGKPIFKG----KDYVNQLNQILQVLGTPPDETL----RRIGSKNVQDYIHQLGFIPKVPFVNLYPNANSQALDLLE | .| . |||| | . | . |.. | . .. . .. . .| | . . . .. . NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------F----VCCPDEMYQIMK QMLAFDPQKRITVDEALEHPYL | ..|| .| | | | .. QCWHEDPEDRPTFSEI--HECF |
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Kinase | SLT2.AA | Pkinase_Tyr | 23-89 | 25 | 3e-06 | 22.01 | Pfam | 1-70 (270) | Show / Hide |
Range on Protein: 23-89 Range on HMM: 1-70/270 Sequence Identity: 25% (18 aa) FQLIKEIGHGAYGIVCSARFA--EAAEDTTVAIKKVTNVFSKTLLCKRS-LRELKLLRHFRGHKNITCLY ...|..|.||.| |. .. . ....||.|.. . .. .|... .||.|..... |.|| .|| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY |
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Kinase | SLT2.AA | Pkinase_Tyr | 132-176 | 46 | 4e-06 | 21.52 | Pfam | 115-159 (270) | Show / Hide |
Range on Protein: 132-176 Range on HMM: 115-159/270 Sequence Identity: 46% (21 aa) SFTYQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLAR .. .|| .|. | .| |||| | ||. . . ||||||||| QMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR |