Gene SCY1 (Bakers Yeast)
SCY1
Sequence
Protein domains of SCY1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | SCY1.AA | SCY1 | 27-53 | 37 | 0.009349 | 5.48 | In-house | 1-23 (337) | Show / Hide |
Range on Protein: 27-53 Range on HMM: 1-23/337 Sequence Identity: 37% (10 aa) WSIYTGRPKSSSSSSPSKVSIFMFDKK | |. |. |... ...|.| |||| WKIHNGTKKYTG----QECSVFVFDKK |
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| Kinase | SCY1.AA | SCY1 | 58-323 | 26 | 7.1e-118 | 397.9 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 58-323
Range on HMM: 1-337/337
Sequence Identity: 26% (89 aa)
YLLHYGIIKSKSGSRDKVLIQEAY---------------EILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQG-
...|.|..| ..|....|...... |.|..||..|..|.|||||..|.||||.....|..||.....||.|....|.......|.
WKIHNGTKK-YTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKT
-------------------HVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISG---------LGYLVKIPPGTNTSEYFLPQYD
...|...|..||.|...||.|.||....||.||.|..||.|.|.||||.| ... ..|..|......| .|..
QDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEW
--------------PRVPPFMHLQLNYTAPEIVFE-------------NTLTFKNDYFSLGLLIYFLYTGKDLFRSENST-SEYKLEYNKFESKISTMSW
...||... .....|||...| ..|...|.||||.||...|.||......||. ......|.......|...|
REMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWW
DNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEF
|.|.......|.||...|...|...|.|.........|
DHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
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| Kinase | SCY1.AA | Ciliate-E2-Unclassified | 153-324 | 16 | 1.9e-12 | 39.55 | In-house | 149-352 (352) | Show / Hide |
Range on Protein: 153-324 Range on HMM: 149-352/352 Sequence Identity: 16% (36 aa) ILQLVNALDFVHNRASFVHLNIQPRAIFINENS---DWKISGLGYLV-----------------KIPPGTNTSEYFLPQYDPRVPPFMHLQLNYTAPEIV . |....|.. | ..| .|.| |....| ||...| ... .. |.| |. |||||. FAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQ----------YTAPEVL FENTLT----FKNDYFSLGLLIYFLYTGKDLFRSENSTS---------------EYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIP----KLINRDIY .. .| |..||| ..|.. .|. | ..|... ... . .. . ... ..| .| ..... ..| |... .. QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPN SRYDNITLILDSEFF .|. .. || .| KRI-TFEQILNHPWF |
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| Kinase | SCY1.AA | Ciliate-E2 | 89-324 | 16 | 6.2e-11 | 33.76 | In-house | 84-365 (365) | Show / Hide |
Range on Protein: 89-324
Range on HMM: 84-365/365
Sequence Identity: 16% (50 aa)
NNLAKLKHPNILTLIEPLEE-HSKNFMFVTEFVTS-SLETVFRET---DDEEQNFLQGHVKDNIVVQRGILQLVN---------------ALDFVHNRAS
|.| .|.||||. ..| .| .|. .|.|.. .|. .. ..|.. . . . ... . |... || . |.. .
NILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN
FVHLNIQPRAIFINENSDWKISGLGY-----------------LVKIPPG----TNTSEYFLPQYDPRVPPFMHL------------QLNYTAPEIVFEN
.| .| | |.. ||. .|. .. . . .. .. . ..| ||||.
IIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD-------------QIIQQNMFNTICGTPGYMAPEILNGK
T---------LTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDN-----IFSKVPQKLRHCIPK----LINRDIYSRYDNITL
..| |..||| ..|.. .|| | .. . |......|. .. .. |..|. . | | ....| |....
KYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ
ILDSEFF
||. ..|
ILNHPWF
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| Kinase | SCY1.AA | AGC | 225-324 | 19 | 2.2e-09 | 18.87 | In-house | 272-395 (395) | Show / Hide |
Range on Protein: 225-324 Range on HMM: 272-395/395 Sequence Identity: 19% (25 aa) NYTAPEIVFENTLTFKNDYFS--LGLLIYFLYTGKDLFRSENST------SEYKLEYNKFESKISTMSWDNIF-----------SKVPQKLRHCIPKLIN .| ||||. .. |. | || |.| . ||. |...| . ..| .. . ...|. | ... . ... | ||.. EYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLC RDIYSRYDN---------ITLILDSEFF .| | . . | . ..| KDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | SCY1.AA | S_TKc | 63-324 | 15 | 2.6e-09 | -40.33 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 63-324 Range on HMM: 1-231/231 Sequence Identity: 15% (45 aa) GIIKSKSGS-----------RD-------KVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTS---SLETVFRETDDEEQNFLQG | | |. .. |.. | .|. . | | .|||| .|.. .. ... .|.|.. .| .. .. . .| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF--- HVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPPFMHLQ--LNYTAPEIVFENTLTF . . .... . |...||.. |.. ..| . | |...| ||. | .. ... ..| |||.. .. -PFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPEVL---GYGK -KNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLIL-D-----SEFF | | |.| ..| ...|. .|. .... ..| .. ... | |. ..| |. . . ..| CKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | SCY1.AA | GRK | 226-251 | 40 | 5.8e-05 | 11.24 | In-house | 172-198 (272) | Show / Hide |
Range on Protein: 226-251 Range on HMM: 172-198/272 Sequence Identity: 40% (11 aa) YTAPEIVFENT-LTFKNDYFSLGLLIY | |||.. . . .| |..||| .|| YMAPEVLQNERAYDFSPDWWSLGCMIY |
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| Kinase | SCY1.AA | Ciliate-B1 | 225-262 | 38 | 7.2e-05 | 13.12 | In-house | 193-231 (290) | Show / Hide |
Range on Protein: 225-262 Range on HMM: 193-231/290 Sequence Identity: 38% (15 aa) NYTAPEIVF-ENTLTFKNDYFSLGLLIYFLYTGKDLFRS || |||| . ...| |. |.|...| ..|.. ||.| NYMAPEILNFNQQYDKKVDIWSFGCIMYEIITNEQLFCS |
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| Kinase | SCY1.AA | GRK | 226-251 | 50 | 8.8e-05 | 13.15 | In-house | 167-192 (265) | Show / Hide |
Range on Protein: 226-251 Range on HMM: 167-192/265 Sequence Identity: 50% (13 aa) YTAPEIVFENTLTFKNDYFSLGLLIY | |||.| . || |...|| ||| YMAPEVVKNERYTFSPDWWGLGCLIY |
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| Kinase | SCY1.AA | Ciliate-D1 | 242-260 | 31 | 0.000168 | 15.72 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 242-260 Range on HMM: 1-19/19 Sequence Identity: 31% (6 aa) DYFSLGLLIYFLYTGKDLF | .|.|...| . .|.. | DIWSFGCILYEMLFGQPPF |
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| Kinase | SCY1.AA | Ciliate-E7 | 155-191 | 40 | 0.000479 | 10.39 | In-house | 107-142 (290) | Show / Hide |
Range on Protein: 155-191 Range on HMM: 107-142/290 Sequence Identity: 40% (15 aa) QLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISG | || ..| . .| .|| | ||.| | |||. QILRALHYIHS-QKIYHTQLTPRFIQINQNCDIKISD |
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| Kinase | SCY1.AA | Pkinase | 224-324 | 15 | 0.000676 | 14.86 | Pfam | 175-293 (293) | Show / Hide |
Range on Protein: 224-324 Range on HMM: 175-293/293 Sequence Identity: 15% (19 aa) LNYTAPEIVF-ENTLTFKNDYFSLGLLIYFLYTGKDLFRSE----NSTSEYKLEYNKFESKISTMSW-DNIFS--------------KVPQKLRHCIPKL ..| |||.. . . | | .|.|...| ...|. .|... | ..... ... . ... .. .. | .... ... | .. PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC INRDIYSRYDNITLILDSEFF ...| ..|. .. || ...| LCKDPKKRPT-AEQILQHPWF |
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| Kinase | SCY1.AA | ULK | 84-119 | 30 | 0.000831 | 9.46 | In-house | 57-98 (324) | Show / Hide |
Range on Protein: 84-119 Range on HMM: 57-98/324 Sequence Identity: 30% (13 aa) LRNQANNLAKLK---HPN--ILTLIEPLEEHS-KNFMFVTEF |.| ... ||| ||| | |.. .|. .|. ...|. LKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEY |
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| Kinase | SCY1.AA | ULK | 226-257 | 32 | 0.033194 | 3.7 | In-house | 213-249 (324) | Show / Hide |
Range on Protein: 226-257 Range on HMM: 213-249/324 Sequence Identity: 32% (12 aa) YTAPEIVF----ENTLT-FKNDYFSLGLLIYFLYTGK | ||.|. . . .| | .||| ..| . .|| YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGK |
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| Kinase | SCY1.AA | Pkinase | 91-128 | 28 | 0.103048 | 7.14 | Pfam | 54-89 (293) | Show / Hide |
Range on Protein: 91-128 Range on HMM: 54-89/293 Sequence Identity: 28% (11 aa) LAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVF ...|.||||..|.. |. ... .|.|.. |. |. MKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLY-VM |
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| Kinase | SCY1.AA | Ciliate-D1 | 397-415 | 21 | 4.100295 | 0.17 | In-house | 1-19 (19) | Show / Hide |
Range on Protein: 397-415 Range on HMM: 1-19/19 Sequence Identity: 21% (4 aa) LIIKIGSTLSQLSFQEKVY | .| .| .. |... . DIWSFGCILYEMLFGQPPF |
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