Gene RIO1 (Bakers Yeast)
RIO1
Sequence
Protein domains of RIO1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | RIO1.AA | RIO1 | 101-301 | 62 | 1.2e-168 | 566.62 | In-house | 1-225 (225) | Show / Hide |
Range on Protein: 101-301 Range on HMM: 1-225/225 Sequence Identity: 62% (143 aa) PVID--------------------------EETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRI .||| .||..|...||.|.||||||||||||||||||||.|||||||||.....||||||||||||||.|||||| QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI YQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKLYMIDVSQSVEPEHPMSL ||| .||.|.||.||.|||.|||... .|.|.|.||||.||.||..|||||.|..|||..||.||||||||||||...|.|||||||||||||..||.|| YQS-EIPCPEPIMVKSNVLMMEFIGK-DGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSL DFLRMDIKNVNLYFEKMGISIFPERVI .|||||.||||.||.|....|||.|.| EFLRMDCKNVNMYFMKHNVIIFPVRDI |
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| RIO | RIO1.AA | RIO | 47-307 | 44 | 2.2e-143 | 483.54 | SMART | 1-253 (253) | Show / Hide |
Range on Protein: 47-307 Range on HMM: 1-253/253 Sequence Identity: 44% (120 aa) DKANRATVENVLDPRTMRFLKSMVTRGVIADLN--GCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGE ||...||.|.|.||||...|..||.||.|...| ||.|||||||||||..| ..|... |.|.|||.||...||...||..|. DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGG-----------------DFDKNGNECAVKIYRTSTTEFKRMWRYIQGD FRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIF--HYYHTMVAYMRLLYQVCRLVH |||.......|.|||...|||||||||.|.|.. ..|.||||.....||||||... .|.. |.|||.........| .||.... ||| .|..|.||| FRFKHGYHHINWRKMVRLWAEKEFRNLQRMYEA-GVPCPKPIAWRRHVLVMEFIGD-DGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVH ADLSEYNTIVH------DDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGISIFP-ERVIFQFVIS |||||||...| |.|...||.|||||..|||.|.||..||.|.. .|...|.. .. .|.||..... ADLSEYNMLYHDLEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG |
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| Kinase | RIO1.AA | RIO | 101-315 | 37 | 8.10000000001e-136 | 457.51 | In-house | 29-276 (276) | Show / Hide |
Range on Protein: 101-315 Range on HMM: 29-276/276 Sequence Identity: 37% (94 aa) PVIDEETGQYEVLETDGSR---------AEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNN .....|...|......|.. .|.||||..|....||||..|.||||.|......||.|.|...|||||.||.||.||| ..|.|.||..|.. IGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLWAEKEMRNMKRLYQS-GFPCPEPIDYKRH VLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKL-------YMIDVSQSVEPEHPMSLDFLRMDIKNV ||||||... .....||.............|.||....||| |||.|||||.|..|.|...||.|. ||||..|.||..||..|...|.|.|.| VLVMEFINH-DQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCV NLYFEKMGI-SIFPERVIFQFV------------------ISETLEKFKG |..|.|... ..||||..|.|| ...||..... NMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM |
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| Kinase | RIO1.AA | RIO1 | 89-301 | 42 | 9.1e-115 | 358.37 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 89-301 Range on HMM: 1-200/200 Sequence Identity: 42% (93 aa) NVYHAFA-GTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIE ||||| . ||. |.|.|||.|....||...||.|..||||. ...||.|.|...|||||||||||.|. | .|.||||. NVYHAYSMEDGKD--------------------ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAG-VPCPKPID VKNNVLVMEFLSRGNGFASPKLKDYPYKNR---DEIFHYYHTMVA-YMRLLYQVCRLVHADLSEYNTIVHDD-KLYMIDVSQSVEPEHPMSLDFLRMDIK ....||||||... .| . |.|||...... .|. ..|. .. ||| .|| |.|||.||||||..|||| |...||..|.||. ||..|.||..|.. WNRHVLVMEFIGDKDGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCR NVNLYFEKMGIS--IFPERVI |.. .|...|.. .. .|.| NIINFFRRKGVDERVMDFREI |
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| Kinase | RIO1.AA | RIO3 | 51-293 | 40 | 7.4e-59 | 196.88 | In-house | 1-230 (254) | Show / Hide |
Range on Protein: 51-293 Range on HMM: 1-230/254 Sequence Identity: 40% (99 aa) RATVENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNS .| | .||.| .. || |.. . ||..||||. |.||. |. ...| . |. | . |||..||.. ||.|..|. .|||.. HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGS-----MEDEKEDSKVIPT-----ICAIKVFKTTLNEFKNRDKYIKDDFRFKDR RSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNT |. ||||. ..||||| || |. ..| || | . .| .||| |. . .||||. | .|. |. . || || | |||||||||| FSKLNPRKIHRMWAEKEMHNLARMQRAG-IPCPTVVLLKKHILVMSFIGH-DQVPAPKLKEVKL-NSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNM IVHDDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGI . | |...||||||||| || |.|| | .|| .|.| |. LWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGV |
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| Kinase | RIO1.AA | RIO1 | 56-99 | 59 | 2.8e-18 | 59.88 | In-house | 1-44 (225) | Show / Hide |
Range on Protein: 56-99 Range on HMM: 1-44/225 Sequence Identity: 59% (26 aa) NVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGK |.|||| | |.|||.| ..|||.|||||.||||| || QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGK |
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| Kinase | RIO1.AA | RIO | 54-99 | 32 | 7e-16 | 50.93 | In-house | 1-46 (276) | Show / Hide |
Range on Protein: 54-99 Range on HMM: 1-46/276 Sequence Identity: 32% (15 aa) VENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGK .| ..||.| .. ||.||.. ..| ..|||...||. . |. YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGE |
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