IPL1

Species: Bakers Yeast
Alias: IPL1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
IPL1.AA Protein Refseq_NP 367 Regulation of yeast chromosome segregation; Ipl1p [Saccharomyces cerevisiae] Fasta, JSON
IPL1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of IPL1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IPL1.AA Aur 104-355 57 6.30000000001e-222 592.83 In-house 1-257 (257) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-257/257
Sequence Identity: 57% (147 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH--GPFND
||.||.|||||||.||..||..|..|.|||||.||.|.||....|.|||..||..|||||  | ||||||..|.||..|| ..||.||.|. .  . |..
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

ILASDYIYQIANALDYMHKKNIIHRDIKPENILIG-FNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDHTIDAWALGVLAFELLTGAPP
..|  |.|||.|||||.|.||||||||||||||.. .|..||. |||||...|..|||.| |||.||..|||||....||..| |.||||..||..|.||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FEE-EMKDTTYKRIA-ALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI
||. |..|.||.||  ..||..||.||..|.||| |.|..||| ||.| ....||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI

Kinase IPL1.AA AGC 104-355 25 7.89999999999e-117 303.14 In-house 1-395 (395) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-395/395
Sequence Identity: 25% (102 aa)

FELGKKLGKGKFGKVYCVRHR------STGYICALKVMEKEE--------IIKYNLQKQ-------FRREVEIQTSLN----------HPNLTK-SYGYF
||. | .||| ||||| ||..      .|| ..|.||..|..         .....  .       ...| .| . .|          ||...|  .  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

HDEKR--VYLLMEY---LVN-----GEMYKLLRLHG-----PFNDILASDYIYQ-------IANALDYMHK-KNIIHRD-IKPENILIGFNNVIKLTDFG
.|...  .|..|||    ||     | .  .|.|.|      |.   |  |. .       |. ||.|.|. ..||||| .||||||.  .  |||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSIINPPEN---------------------------------------------------RRKTVCG--TIDYLSPEMVESREYDHTIDAWA--LGVLAF
 . ... ..                                                   | .| ||  | .|..||..    |... | |.  ||.| .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELLTGAPPFEEE----------MKDTTYKRIAAL------DIKMP----------SNISQDAQDLILKLLKYDPKDRMR----------LGDVKMHPWI
|.||| |||  .           .. ....|         ..|.|          ...|..|.||| |||. ||..|              ..| ||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase IPL1.AA S_TKc 104-355 33 1.8e-101 344.31 SMART 1-231 (231) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVN--GEMYKLLRLHGP---
.|...|.||| |||||..||..|| |.|.|..           ...|||..|  . .|||. | |..|.| ...|. |||. .  |....... .|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYDH-TIDAWALGVLAFEL
   |.   |  |.|||..||.|.|...|||||.||||||.    .||..||| . .       .|.||| .|..||..    |..  .| |..|.. .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGAPPFEEEMKDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKM-------HPWI
|.| |||.    ....|.|           |..| |.| |.|..||..|.   ..         |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IPL1.AA CAMK 109-355 22 5.2e-88 283.6 In-house 1-425 (425) Show / Hide
Range on Protein: 109-355
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

KLGKGKFGKVYCVRHRSTG------------YICALKVMEKEEIIK-------------------------YNLQKQFRREVEIQTS-------LNHPNL
.||.| ||||. ..|..|.              .| |...|. . .                          . .|..|||.||  .       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TKSYGYFHD-------------------EKRVYLLM---EYLVNGEM----YKLLRLHGP---------------FNDILASDYIYQIANALDYMHKKNI
 | | .. |                   .|..|. |   ||  .||.    .  .. ||.               |.   |. |. ||. |..|.|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILIGFN-----------------NVIKLTDFGWSIINPPEN------------------------RRKTVCGTIDYLS-PEMVES------
.|||.||||||.  |                 | ||..||| ... .| .                          ||.|||  | . ||....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------REYDHTIDAWALGVLAFELLTGAPPFEEE-------------MKDTTYKRIAALDIKMPSN------------------------ISQDAQD
        . |.  .| |..||. . .|.| |||...                 ....| . .  .|.                         .||...|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LILKLLKYDPKDRMRLGDVKMHPWI
|| |.|..||..|| . ... |||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase IPL1.AA CAMKL 104-355 32 8.8e-85 270.47 In-house 1-297 (297) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-297/297
Sequence Identity: 32% (96 aa)

FELGKKLGKGKFGKVYCVRH-RSTGYICALKVMEKEEII-KYNLQKQ-----------FRREVEIQTSLN---HPNLTKSYGYFHDEKR------VYLLM
...|| |||| ||||   .| | ||   | |...|. |  . . .|             |||..|. .||   |||  | |  . ...       .|| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLVNGE--MYKLLRLH----GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNN--VIKLTDFGWSII-----NPPENRRKTVCGTIDYL
||  .||  ..  .. |    |..    |  |  ||  |..|.|...|.||||||||||.  |.  .||..||| |..     ..|..  || ||.  | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEMVES--REYD-HTIDAWALGVLAFELLTGAPPFEEE--------MKDTTYKRIAALDIKMP--SNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI
.||....  ..||   .| |..||. . ...|. ||...         . . |..|  .  ..|  . .| |..||| |.|. .|..|. . ....||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase IPL1.AA Pkinase 104-355 30 5.5e-82 283.49 Pfam 1-293 (293) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFR-REVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNG----EMYKLLR--LH
...|.|.|.| ||.||  .|..|| | |.|...|... .  .|  .| .|..|  .|||||  . |..|.|....|. |||. .|    . . ...   |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--NDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVI----KLTDFGWSII--NPPENRRKTVCGTIDYLSPEMVE-SREYDHTIDAWAL
|.|   .  . .|.|||. .|.|.|...|||||.|||||||  |..|    |..||| .    . .    .|.|||..|..|| .  ...|.. .| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLAFELLTGAPPFEEE------MKDTTYKRIAALDIKMPSNIS---------------------QDAQDLILKLLKYDPKDRMRLGDVKMHPWI
|.. .|.|.| ||| ..       ..  ..||   ... ..  .                     ....|.| ..|..|||.|    ... |||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase IPL1.AA Ciliate-E2 104-355 25 1.7e-81 277.05 In-house 1-365 (365) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

FELGKKLGKGKFGKVYCVRHRSTGY-----------------------ICALKVMEKEEIIKYNLQKQFRREVE----------IQTSLNHPNLTKSYGY
... ||.|.| ||.|| ........                       | |.|.|.| .|.  .  ..  ||..          |. .|||||. | | .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FH--DEKRVYLLMEYLVNGEMYKLLRLH-----------GPFNDILASDYIYQIAN---------------ALDYMHKKN-IIHRDIKPENILIGFNNVI
|   |.. .|| |||.  |....... .           ..|..  ......||..               || |.|.|| ||||||||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGWSIINPPENRRKT--------------------------------VCGTIDYLSPEMVESRE---------YDHTIDAWALGVLAFELLTGAPP
|..||| | .. ..| ..|                                .|||  |..||.... .         ||. .| |.|||. .|.|.| ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FEEEMKDTTYKRIAALDIKMP------------------SNISQDAQDLILK----LLKYDPKDRMR-LGDVKMHPWI
|        .. |   .|. |                   ..||...||| |    .|..||. |.    ... |||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase IPL1.AA MARK 104-355 35 1.7e-81 266.17 In-house 1-262 (262) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-262/262
Sequence Identity: 35% (94 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFH--DEKR-VYLLMEYLVNGEMYKLLRLH--GP
....| .|.| ..||. ..|. ||   |.|..||. . . .  | ..||.||  .|.||| .| . ..   .|.. .|| |||  .||.|  .. |  |.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNN--VIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESREYD-HTIDAWALGVLAFELL
    .|  .  ||  |. |.|.|||.|||||||||||  |.   ||..|||.||. ||... .| |||  | .||......||   .| |.|||. . ..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGAPPFEEEM--KDTTYKRIAALDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI
.|  ||..      . ||.| . . . |...| ....|| .||. .|..|. . .. .|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase IPL1.AA RSK 107-355 34 2e-77 263.54 In-house 1-278 (278) Show / Hide
Range on Protein: 107-355
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

GKKLGKGKFGKVYCVRHR---STGYICALKVMEKEEIIKYNL-QKQFRREVEIQTSLN-HPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGP---
 | ||.| .|||. .|      || | | || .| .|.. .  ..  ..|..|    . ||.. . .  |..|. .|| |||.  ||... |. ..    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGF---NNVIKLTDFGWSIINPPE--NRRKTVCGTIDYLSPEMVE---SRE-YDHTIDAWALGV
|    |..|...|. |....|.. |||||.||||||      .  ||||||| . .....  .. .| |.||.|. |||.     .. .|.  | | |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAFELLTGAPPFEE---EMKDTTYKRIAALD--IKMP--SNISQDAQDLILKLLKYDPKDRMR-----LGDVKMHPWI
| .|.|||.|||     . .. . |||   .   .||  ...||.|.||| |.|. ||..|       . ..| |||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase IPL1.AA PLK 104-355 33 6.4e-73 236.83 In-house 1-258 (258) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-258/258
Sequence Identity: 33% (87 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLVNGEMYKLLRLH-GPFNDI
.| |. |||| | |.| ... .|... | ||  |. ..| .. .  ..|.||. .|.|||  | . .| |.  ||...||  |...  ... .  ...  
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

LASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWS-IINPPENRRKTVCGTIDYLSPEMVESRE--YDHTIDAWALGVLAFELLTGAP
 . .|.|||...| |.|...|||||.|. |...  |...|. ||| .  ..... |.||.|||  | .|| ..  .  ..  .| |.||.    ||.| |
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFEEEMKDTTYKRIAALDIKMPSN--ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI
||| .   .|||||   .  .|..  ||. |.||| |.|. .| .|  .  . .||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF

Kinase IPL1.AA Ciliate-E2-Unclassified 104-355 25 3.2e-72 246.23 In-house 1-352 (352) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQ-----FRREVEIQTS-----------------LNHPNLTKSYGYFHDEKRVYLLM
....|..|.| ||||| ..|...... |.| | |  |.| .....     .  . . . .                 ..||.. | . .| |.. .|. |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLVNGEMYKLLRLHGP-----------------FNDILAS-----DYIYQIANALDYMHKKN-IIHRDIKPENILIGFNN---VIKLTDFGWSII----
||. .|.. . ..  .                  | .  |.     .|..|| ..|.|.|.|| ||||||||||||.  |.    ||..||| |.     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------NPPENRRKTVCGTIDYL----SPEMVESREYDHT----IDAWALGVLAFELLTGAPPFEEEMKDT----------------TYKRIAA
            ...... .|.|||. |.    .||. .. .|||.    .| |.|||...|.|.| .||. . ..                  |. | .
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

LDIK--------MPSNISQDAQDLIL----KLLKYDPKDRMRLGDVKMHPWI
 .|.         | ..|. |.|.|     |.||..|. |. . ... |||.
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase IPL1.AA PKA 104-355 38 6.6e-71 241.88 In-house 1-263 (263) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-263/263
Sequence Identity: 38% (103 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSLNHPNLT-KSYGYFHDEKRVYLLMEYLVNGEMYKLLRLHGPFNDI
||. . ||.| ||.|. .||...| ..|.|.. |.||.. . .     |  | ....||..  | |. |.|..  |..|||   ||| . ||  | |.  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

LASDYIY-QIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRKTVCGTIDYLSPEMVESR-EYDHTIDAWALGVLAFELLTGAPP
 |  |.  ||  ||.|.|..|||.|| |||||||  |  ||.|||| .       | .|.||| .|| ||.. |.  .   .| ||||.| .|.|.| ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FEEE--MKDTTYKRIAALDIKMPSNISQDA---QDLILKLLKYDPKDRM-----RLGDVKMHPWI
|...   .  .|..|.. .||.|.....||    ||| |||  |.. |      .  |.| |.| 
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase IPL1.AA Pkinase_Tyr 104-247 33 5.1e-26 88.74 Pfam 1-156 (270) Show / Hide
Range on Protein: 104-247
Range on HMM: 1-156/270
Sequence Identity: 33% (53 aa)

FELGKKLGKGKFGKVYCVRHR----STGYICALKVMEKEEIIKYN-LQKQFRREVEIQTSL-NHPNLTKSYGYFH-DEKR--VYLLMEYLVNGEMYKLLR
 ..|||||.| ||.||  . .    .|.. .| |.. ||   . . ... | ||..| ..| .|||. . ||    ...   .|. |||  .| ... ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

LH----GPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFG
 |    .|..     .. .|||....| . ||.||||.   |.|.. |||.| .|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase IPL1.AA TyrKc 104-355 24 6.3e-21 76.76 SMART 1-280 (280) Show / Hide
Range on Protein: 104-355
Range on HMM: 1-280/280
Sequence Identity: 24% (70 aa)

FELGKKLGKGKFGKVYCVRHRSTGYICALKVMEKEEIIKYNLQKQFRREVEIQTSL--NHPNLTKSYGYFHDE-------KRVYLLMEYLVNGEMYKLLR
 .|||||| | ||.||  . .   . .| |.. ..       .. |.|| .| ..|  .|||. . ||.  ..       . ....|||  .|   . ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

LHGP-FNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPE------NRRKTV----CGT----IDYLSPEMVESREYD
 |.| ..     .. .|||.  .| |.||.||||.   |.|.| |...| .||| |     .         ...    .|     |  ..||    ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

HTIDAWALGVLAFELLT-GAPPFEE------EMKDTTYKRIAALDIKMPSN--------ISQDAQDLILKLLKYDPKDRMRLGDVKMHPWI
.  | |. ||. .|..| |..| ..      . ..   .  .    . | |         ...  .....  ..||.|| .  ..  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF