Gene DUN1 (Bakers Yeast)

DUN1

Species: Bakers Yeast
Alias: DUN1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CAMK
Family: RAD53

Sequence

Name Sequence Type Origin Length Description Download
DUN1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 281 Kinase domain by global Sugen HMM Fasta, JSON
DUN1.AA Protein Refseq_NP 513 DNA damage response; Dun1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of DUN1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FHA DUN1.AA FHA 56-128 33 5.4e-18 70.89 Pfam 1-73 (73) Show / Hide 
Range on Protein: 56-128
Range on HMM: 1-73/73
Sequence Identity: 33% (27 aa)

TTIGRSRSCDVILS-EPD-ISTFHAEF-HLLQMDVDNFQRNLINVID--KSRNGTFI--NGNRLVK-KDYILKNGDRIVFG
.||||...||..|.  |  .|  |.|. ..              ..|   |.||||.  || |. . . ..|..|||| ||
WTIGRDPDCDIVLDNDPSFVSRHHCEIRRYDNG--------RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG
FHA DUN1.AA FHA 55-112 31 1.5e-15 58.89 SMART 1-49 (49) Show / Hide 
Range on Protein: 55-112
Range on HMM: 1-49/49
Sequence Identity: 31% (19 aa)

VTTIGRSRSCDVILSEPDISTFHAEFHLLQMDVDNFQRNLINVIDKS---RNGTFINGNRL
..||||.  ||..|..| ||  |....  .            .|| .   .|||..||.|.
TWTIGRHS-CDIQLPHPSISRHHCQIR-DGD----------YIIDLGEHSTNGTYVNGRRV
Kinase DUN1.AA RAD53 200-480 47 2e-211 636.74 In-house 1-305 (305) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-305/305
Sequence Identity: 47% (147 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQ-----NDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERI
|...||||.|....||.|..|||.|.||.||.....     ....||..|...|..||....||.|....|.|..|    |...|.|||....||||..|
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTP----QKYYYMVLELMTGGELFNKI

V-RKTC---LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAP
| .|.|   ...|..|..|.|.....||||...|.|||.||||||.|....|.| ||||||||||||....||.||||.||.||..|..|.||||.||||
VSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECP-QVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAP

EVLTKK---------------GYTSKVDLWSAGVILYVCLCGFPPFSDQLG----PPSLKEQILQ-AKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYN
||.|.|               |||.|||.||.|.|||.||||.|||||...    ...|.|||.. .||.|..||||.|......||...|...|..||.
EVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYT

IDEALNHPWF
|||||||||.
IDEALNHPWM
Kinase DUN1.AA CAMK 205-480 26 3.3e-116 376.11 In-house 1-425 (425) Show / Hide 
Range on Protein: 205-480
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

ELGAGHYALVKEAKNKKTG------------QQVAVKIFHAQQNDD-------------------------QKKNKQFREETNILMRVQ-------HPNI
.|| | .. ||....|.|.            |.||.||   .. .|                         .|. |..| | .|....|       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLLDSFVE---------------PISKSQIQKYLVL---EKIDDGEL----FERIVRKTC---------------LRQDESKALFKQLLTGLKYLHEQN
..|.. .                  . ... . |.|.   | .. |||    |..||...|               .  .| . .|.|.. ...|.|..|
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKPENILLNITRRENPSQVQLGPWDE--DEIDIQVKIADFGLA--KFTGEMQF----------------------TNTLCGTPSYVA-PEVLTK-
|.|||.|||||||.   ..... |  .  ||  |. . ..||.|||.|  .. || .|                       .| ||||.|.| |||| . 
IVHRDLKPENILLDDNNDDSDP-V--E-HDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

-------------KGYTSKVDLWSAGVILYVCLCGFPPFSDQL------------GPPSLKEQILQAKYAFYSPY------------WDKIDDS------
             ..|. |.| ||.|||||..|||.||| .               .. |.|.|...|| |..||            ||.| |.      
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

--VLHLISNLLVLNPDERYNIDEALNHPWF
  . .||...|. .|..|..|...|||||.
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase DUN1.AA CAMK1 200-480 35 4.4e-106 309.37 In-house 1-276 (276) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-276/276
Sequence Identity: 35% (106 aa)

YLLGKELGAGHYALVKEAKNKKT---GQQVAVKIFHAQQNDDQKKN---KQFREETNILMRV---QHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGEL
| .|||.|.|  . |.....|.|   |.|.|.|..   .. ..|..   .... | .|. .|   .||||... . .    |.. .  |||.| .  |||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYE---SDNHF--YLVMELVTGGEL

FERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRREN----PSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQ-FTNTLCGTP
|.||| |..   ..   . ||.|  ..|.|...| |||.||||.|.  .  |.    .|                 ||||||.|....   .  | ||||
FDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLY-YDKDEDSKIKRS-----------------IADFGLSKIFDHDENLMKTACGTP

SYVAPEVLTK---KGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDS-VLHLISNLLVLNPDERYNIDEALNHPWF
.|||||||.    |.|  ..|.||.|||.|. |||.||| |  . . | |.|. ..| | ||.||.| |. . ..|...|...| .||.....|||||.
GYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase DUN1.AA S_TKc 200-480 31 5.5e-99 336.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-231/231
Sequence Identity: 31% (94 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDD--GELFERIVRK
| .....| | .. |. ...||||..||.|| .          ...| | .||.. .|||||.|.|.|..         |.|.| .|   |.||..|...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKR

TC------LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTLCGTPSYVAPE
 .      .   . . ...|.. .|.|.|...|||||.|||||||.                      ..||.|||||..       .|.|||| |.|||
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------HIKICDFGLARQL------TTFCGTPWYMAPE

VLTKKGYTS-KVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALN-------HPWF
||   ||.  |.| || |.||| .||| |||.    .  . ..|.              .......|...|. .|..|. . |||.       ||||
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DUN1.AA CAMKL 200-480 31 6e-97 309.92 In-house 1-297 (297) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-297/297
Sequence Identity: 31% (100 aa)

YLLGKELGAGHYALVKEAKN-KKTGQQVAVKIFH--AQQNDDQKKNK------QFRE----ETNILMRVQ---HPNIVNLLDSFVEPIS--KSQIQKYLV
| .||.|| |... || |.. . ||..||.|| .    .||...|..      . ..    | .|.....   ||||. |.. .  |     .  . |||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

LEKIDDGE--LFERIVRKTC----LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKF----
.| .. ||  ||..||.. .    .  .| . .|.|.. ...|.|...|.|||||||||||    ..                 ..||.|||.. .    
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-----------------NIKIIDFGFSNMYRPC

-TGEMQFTNTLCGTPSYVAPEVLTK--KGYT-SKVDLWSAGVILYVCLCGFPPFSDQ----LGPPSLKEQILQAKYAFYSP-YWDKIDDSVLHLISNLLV
  |. |. .| ||.|.| |||.. .  | |   ||| ||.|||||. .||  || |.    .|     .  .. .   | |  | ... .. .||. .|.
IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQ

LNPDERYNIDEALNHPWF
 ||..|..|.. .||||.
VNPEKRPTIHQIMNHPWM
Kinase DUN1.AA Pkinase 200-480 33 1.5e-93 321.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-293/293
Sequence Identity: 33% (105 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFR-EETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDG----ELFERI
| .|. .|.| .. |.....|.||..|||||.  . ....|.   .|  |  |. |..||||| |.|.| .   |. |  |.|.|  . |    .||..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHI--YMVMEYCEGGLYVMDLFDYI

V--RKTCL--RQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKF--TGEMQFTNTLCGTPSYV
   |..|.    .| |  ..|.| ||.|.|...|||||.||||||..  . ....               |||.||||||.  .   . ..|.|||| |.
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA--------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYM

APEVLT-KKGYTSKVDLWSAGVILYVCLCGFPPFSDQ-----LGPPSLKEQILQAKYAFYSPYWDKID-----------------DSVLHLISNLLVLNP
||||.   ..|..||| ||.|.|||  ||| |||...     . .  . ..|..... | .|.|. |                  .. ...|...| ..|
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

DERYNIDEALNHPWF
 .|......|.||||
KKRPTAEQILQHPWF
Kinase DUN1.AA Ciliate-E2 200-480 26 1.6e-87 297.06 In-house 1-365 (365) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-365/365
Sequence Identity: 26% (108 aa)

YLLGKELGAGHYALVKEAKNKKTGQQ-----------------------VAVKIFHAQQNDDQKKNKQFR----------EETNILMRVQHPNIVNLLDS
| . | .| | .. |...|..|...|                       .|.||.. .|   .|. ..            .| ||| ...||||... ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FVEPISKSQIQKYLVLEKIDDGELFERIV-----RKTCLR------QDESKALFKQLLT---------------GLKYLHEQN-IIHRDIKPENILLNIT
| |   |..   |||.| .. |.||..|      |. ..         | | ..||.|                .|.|||..| ||||||||||||.   
FQE---KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

RRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEM--------------------------------QFTNTLCGTPSYVAPEVLTKKG---------Y
                     .||.||||.|.  .                                 . .||.|||| |.|||.| .|.         |
---------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGY

TSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSP--------------YWDKIDDSVLHLISN----LLVLNPDERYN-IDEALNHPW
. |.|.||.||||| .|.| |||          .||.| |. | .|               |.|..... .||..    .|. .|..|.. ....|||||
DYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPW

F
|
F
Kinase DUN1.AA DCAMKL 200-480 37 5.3e-86 267.48 In-house 1-279 (279) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-279/279
Sequence Identity: 37% (111 aa)

YLLGKELGAGHYALVKEAKNKKTG-QQVAVKI-------------FHAQQNDDQKKNKQF--REETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLE
| .|.  | |  | |.|.....|| .. | ||             |  | .  . |.| .    |  |. ...||.|. | ...       . . |||.|
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHW-----DTETHYYLVME

KIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGE-MQFTNTLC
 .  | ||. |.  |     .. ..  .|   |||||| ||.|||||||| |..               .||   . .| .|||||.   . .    | |
YVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCK--------------HEDG-EKSLKLCDFGLACHVNGDFGPLYTVC

GTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPF-SDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF
||| |||||.| ..||  ||| |.||||||. ||||||| |       | .||.|.|. | .|||| | ||.  |||..|. .|. ||   . . ||| 
GTPTYVAPEILMETGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase DUN1.AA Ciliate-E2a 200-480 34 5.8e-86 253.02 In-house 1-275 (275) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-275/275
Sequence Identity: 34% (103 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTC
| . |..| | .. |. |. |.||.| |.|.|.   ... |....|  | ||. .. ||||  | . .   ......  |||.| .. |||...|. . .
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVY---EDENNY--YLVMEYCEGGELYDKIKQCKR

LRQD--ESKALFKQLL-TGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEI-DIQVKIADFGLAKFT--GEMQFTNTLCGTPSYVA----
. .   | . . .|||  || |.| .||.|||.||||||..               . . | . ..||.|||||.|    | ..  . |||| |||    
FFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKN-------------CSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVL

--PEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSD------QLGPPSLKEQILQAKYAFYSPY-WDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWF
  .|||..| |. |.|.||.|||.|  ||| |||                .|. . |. | .|  | |....  .|.. .|. .| .|... .|||||||
NNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEIL-------QQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase DUN1.AA Ciliate-E2-Unclassified 200-480 26 5e-77 262.2 In-house 1-352 (352) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-352/352
Sequence Identity: 26% (100 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDD--QKKNKQFREETN---------------------ILMRVQHPNIVNLLDSFVEPISKSQI
| ..| .| | .. |.....||..|. | |. . .|...  |..||. ..  .                     ||   .||.||.... |     ... 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCF-----QDKQ

QKYLVLEKIDDGELFERIV-RKT----------------CLRQDESK-----ALFKQLLTGLKYLHEQN-IIHRDIKPENILLNITRRENPSQVQLGPWD
  |.|.|....|.|.. |  ||.                ..   ..|      .|.|.| ||.|||..| ||||||||||||..   .            
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------------

EDEIDIQVKIADFGLAKFTGEM----------------QFTNTLCGTPSYV----APEVLTKKGYT----SKVDLWSAGVILYVCLCGFPPFSDQLGPP-
      ..||.|||..|. ...                | ..| ||||.|     ||||| ...|      |.| || ||||| .| | .||.|.     
----NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQH

--------------SLKEQILQAKYAFYSPYW----DKIDDSVLHLIS----NLLVLNPDERYNIDEALNHPWF
               |...|.| .. | .  |    ....... ..|.     .|. ||..|......||||||
QQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase DUN1.AA CAMK-Unique 200-480 23 4.4e-76 250.61 In-house 1-363 (363) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-363/363
Sequence Identity: 23% (88 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQ------------------FREETNILMRVQHPNIVNLLDS----FVEPI------
| ... .| | . .|.|.....||   |.|..  |  .  ||.||                  ...| .|. .| ||||. |.|     |. .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQT-HGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

----SKSQIQKYLVLEKIDDGELFERIVR--------------------KTCLRQ--DESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPS
     .     |.|.| ...|.||. |..                    .. .     ..  .. .||  ..|.|.|.|.|||.|.|||...    .|  
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN-

QVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTN---TLCGTPSYVAP--------------EVLTKKGYTSKV----DLWSAGVILYVCLCGFPPFSDQ
    .  . |...  .|..||||..   . .      | ||||.|.||              ||.   .| ...    |.|| |||.|  ||| |||  .
--HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCE

LGPP-------SLKEQILQAKY-AFYSPYWDK---IDDSVLHLISNLLVLNPDERYNIDEALNHPWF
  .        .. | |....|  | ...|.    | ..   .. ..... || | .. |.| |.|.
CEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase DUN1.AA MARK 200-336 36 2e-42 136.58 In-house 1-137 (262) Show / Hide 
Range on Protein: 200-336
Range on HMM: 1-137/262
Sequence Identity: 36% (51 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRK--
| ..|..| | || || | .|.||..||.||   .. .| .. | .. | .|.....||||. |.. .... ..   | ||..| .  |||...|. .  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQH--QIYLIMEYASGGELYDYIKAHPN

TCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILL
 .|  .| ...|.|.. ...|.|..||.||||||||||.
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI
Kinase DUN1.AA MARK 360-480 40 2.8e-35 112.89 In-house 144-262 (262) Show / Hide 
Range on Protein: 360-480
Range on HMM: 144-262/262
Sequence Identity: 40% (50 aa)

QVKIADFGLAKFTGEMQFTNTLCGTPSYVAPEVLTKKGYT-SKVDLWSAGVILYVCLCGFPPFSDQL-GPPSLKEQILQAKYAFYSPYWDKIDDSVLHLI
..||.|||..    . |  || ||||.| |||.. || |.  ||| || ||.||. .||  || ..  .   |...||  ||  . ..   . ..  .||
NIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCH---VSKECRNLI

SNLLVLNPDERYNIDEALNHPWF
. ||..||.||  |.| ..|||.
QRLLTVNPEERPTIEEIMKHPWM
Kinase DUN1.AA TyrKc 200-480 21 1.3e-15 29.99 SMART 1-280 (280) Show / Hide 
Range on Protein: 200-480
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

YLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRV--QHPNIVNLLDSFVEP----ISKSQIQKYLVLEKIDDGELFER
  |||.|| |..  | ... |   .|||||  ..         . |..| .|....  .|||||.|.   ...    ..  ..  ..|.|  . | | ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL--MIVMEYMPHGDLKDY

IVRKTC-LRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEM-------QFTNTLC--G
. ..   |  ..      |   |  |||..|.||||.   |.|..  .                   .|||.||||... ..        .   .    |
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG

TPS-----YVAPEVLTKKGYTSKVDLWSAGVILY-VCLCGFPPFSDQ----LGPPSLKEQILQAKYAFYSPY-----WDKIDDSVLHLISNLLVLNPDER
. .       |||.. .. .|.| | || || .. ..  | .| ...    . .  . |.. | ..    |.          | .  ...     .|..|
GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR

YNIDEALNHPWF
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PTFSEI--HECF
Kinase DUN1.AA Pkinase_Tyr 200-264 29 6e-13 44.47 Pfam 1-70 (270) Show / Hide 
Range on Protein: 200-264
Range on HMM: 1-70/270
Sequence Identity: 29% (21 aa)

YLLGKELGAGHYALVKEAKNK----KTGQQVAVKIFHAQQNDDQKK--NKQFREETNILMRV-QHPNIVNLL
  .||.||.|..  |.... |    .|...||||.    .. ...    . | .| .|..   .|||||.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase DUN1.AA Pkinase_Tyr 315-412 28 2.3e-07 25.58 Pfam 123-205 (270) Show / Hide 
Range on Protein: 315-412
Range on HMM: 123-205/270
Sequence Identity: 28% (29 aa)

GLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFT-NTLCGTPS---YVAPEVLTKKGYTSKVDLWSAGVI
|. ||...|.||||.   |.|..                    . .|||.|||||.   .      .  |..      |||..  . .|.| | || || 
GMEYLESKNCIHRDLAARNCLVTE-------------------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVL

LY
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MW