Gene CMK2 (Bakers Yeast)

CMK2

Species: Bakers Yeast
Alias: CMK2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
CMK2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 263 Kinase domain by global Sugen HMM Fasta, JSON
CMK2.AA Protein Refseq_NP 447 Calmodulin-dependent protein kinase; Cmk2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of CMK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CMK2.AA CAMK1 47-309 46 1.2e-181 532.83 In-house 1-276 (276) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-276/276
Sequence Identity: 46% (128 aa)

YIFGRTLGAGSFGVVRQARKLST---NEDVAIKILL-KKALQGNNVQ-LQMLYEELSILQK---LSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRIL
|.|| ..|.|.|..|... . .|   ....|||..  ||.......| ...|. |..|..|   ..||||..|..|.||...||.|..| |||||||||.
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

SRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLV--IADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQ---DGHGKPCDIW
 .|..|| ||..|. |||.||||||||..||||||||| ||.||.|.|...  |||||..|.....|.| ..| |..||||||||..   ....|.||.|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMW

SIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISID-VKRFILKALRLNPADRPTATELLDDPWI
|||||||.|||||.|| .|.|. .. |..  .....|..|.|||||   .| || . | ..|  |.|... |..|||
SIGVITYILLCGYPPFYDENVDNELFEKIK-KCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CMK2.AA CAMK 52-309 24 2e-116 376.84 In-house 1-425 (425) Show / Hide 
Range on Protein: 52-309
Range on HMM: 1-425/425
Sequence Identity: 24% (104 aa)

TLGAGSFGVVRQARKLSTN------------EDVAIKILLKKALQG------------------------NNVQLQMLYEELSILQKLS-------HPNI
||| ||||.|. ..  .|.            . |||||. || |..                        . . ..... |..|..||.       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSFKDWFES-------------------KDKFYIVT---QLATGGEL----FDRILSR---------------GKFTEVDAVEIIVQILGAVEYMHSKNV
... ...|.                   ....|.|.    ...||||    ||.| ..               |.||| .|  .. ||. ||.|.||.|.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPENVLYVDKSENSP--------------LVIADFGIAKQLKG-----------------------EEDLIYKAAGSLGYVA-PEVLTQ------
|||||||||.|..|....|.              . |.||| |.....                       | .. .   |...|.| |||| .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------DGHGKPCDIWSIGVITYTLLCGYSPFIAE-------------SVEGFMEECTASRYP-VTFHMPY---------WDNISID--------VKR
        ...|..||.||.|||.|..||||.|| ..             . .  .|  .. .|    ....          ||.|| .        .| 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FILKALRLNPADRPTATELLDDPWI
.| | |. .| .|.|... |..||.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CMK2.AA S_TKc 47-309 35 1.4e-98 334.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-231/231
Sequence Identity: 35% (100 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATG--GELFDRILSRGK--
| ..|..| |.||.|...|. .|.. |||||.            .... |..||.|  ||||| ..|.|.. |..|.|. .. |  |.|||.| .||.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGK-PCDIWSIGV
    |.| .|  .. ||. |.||.||....||||||||.|  .      . |.|||.|.||       .   |.. |.|||||   |.|| .||.||.|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

ITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLD-------DPWI
| | .|||| ||    ..  .. .                 | ..| || | |. .|..|||| |.|        .||.
ILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CMK2.AA CDPK 47-309 39 1.4e-93 287.42 In-house 1-271 (271) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-271/271
Sequence Identity: 39% (108 aa)

YIFGRTLGAGSFGVVRQARKL-STNEDV-AIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIV--TQLATGGELFDRILSRGK
|.....|| |.||.|| . .  .||.   |.||  |. .. .. | |.. .|. || .| ||||. .   .. .. .|||  | . |||||||.| ..|.
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVK-DKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH

FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENS----PLVIADFGIAKQLKGE----EDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWS
||| .| .|. ||| || |.||.|.|||||||||.|.  |...|    .... |.|..|. ...    .. ... .|   |.||||| .    . |||||
FTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWS

IGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWI
.||| |.||||| || ... .  ||     .|  .|  | ||.|| . |  | | |  .| .| .| . |..||.
CGVILYILLCGYPPFYGKNDQEIMEKVKKGKY--SFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CMK2.AA CAMKL 47-309 31 7.9e-91 290.09 In-house 1-297 (297) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-297/297
Sequence Identity: 31% (96 aa)

YIFGRTLGAGSFGVVRQARK-LSTNEDVAIKILLKKALQGNNVQLQM-----------LYEELSILQKLS---HPNIVSFKDWFESKDK------FYIVT
|..|.||| ||||.|. |.  . |.| |||||. || .. . . ...           .. | .|...|.   ||||... . .| ...      .|.|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

QLATGGE--LFDRILSR----GKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQ---L-KGEEDLIYKAAGSLGY
 .. |||  |||.| ..    |...| .|  .  ||. ||.|.||...||||.||||.|  ..  |  . |.||| . .     .|....     ||. |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEVLTQ--D-GHGKPCDIWSIGVITYTLLCGYSPFIAESV-------EGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLD
 |||..    .  .|.. ||||.||| |...||| || ....          ... . .     ...| |  .| |....| | |  || .|||. ... 
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMC---G-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

DPWI
.|| 
HPWM
Kinase CMK2.AA Pkinase 47-309 34 2.1e-89 308.15 Pfam 1-293 (293) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-293/293
Sequence Identity: 34% (101 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGG----ELFDRIL--SR
| .||..|.||||.|..... .|.. ||.||. |.    .  |   .  |..|...|.||||| ..||||.||. |.|. .. ||    .|||.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKF--TEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSEN-SPLVIADFGIAKQL-KGEEDLIYKAAGSLGYVAPEVLT-QDGHGKPCDIWSI
|.|  .| ..  .. ||| ..||.||....||||||||.|.... .. ... |.|||.|||.        .  .|...|.||||.  . ..|...|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVITYTLLCGYSPFIAE----SVEGFMEECTASRYPVTFHMPYWDNIS-----------------IDVKRFILKALRLNPADRPTATELLDDPWI
|.| | .|||. ||  .    ...     |   . |. |. |.|..||                  . | || . |...|..||||...| .||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CMK2.AA Ciliate-E2a 47-309 32 2.9e-89 262.88 In-house 1-275 (275) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-275/275
Sequence Identity: 32% (89 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEV
| | . .| |.||.|. |... |... |.|.. | ... .  . . .. |..|...|.||||  . . .|... .|.|. .  ||||.|.|   ..|.| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--DAVEIIVQIL-GAVEYMHSKNVVHRDLKPENVLYVD-KSEN---SPLVIADFGIAKQLKGEED-LIYKAAGSLGYVA------PEVLTQDGHGKPCDI
  .. .|. |.|  ...|||..|..||||||||.|. . ....   | ..|.||| |.. .. |   ...  |. ||||      .|||..   .. ||.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

WSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPY-WDNISIDVKRFILKALRLNPADRPTATELLDDPWI
||.||| |.||||..|| .....   ..  .  .   |  |  | ..| . | .. | |  .|  |.||...|..|| 
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKI--DFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CMK2.AA RAD53 47-309 33 5.6e-87 259.05 In-house 1-305 (305) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-305/305
Sequence Identity: 33% (103 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQ---GNN-VQLQMLYEELSILQKLSHPNIVSFKDWFESK-DKFYIVTQLATGGELFDRILSRG
|.....||.| ||.|. | . .| . |||||. || .    ...      . .|. ||.||.||.|....|.|... . .|.|  |.||||||..| |..
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

K----FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENS---------------PLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLT
.    |.| .. ..  |.. || | |... .||||||||.|. ...|.                 . |.||| .| . ||  .     |.. ||||||.|
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFV-GEGSFMKTMCGTPQYVAPEVIT

QDGH---------------GKPCDIWSIGVITYTLLCGYSPFIAE-----SVEGFMEECTA-SRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTAT
  ||               .| .|.||.|.|.|..|||| ||. .     .   . |  .   .|   |  |||| ||  .| .| . | ..|  |.|. 
SKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKY--HFPHPYWDRISEEAKDLIKWMLCVDPEKRYTID

ELLDDPWI
|.|  ||.
EALNHPWM
Kinase CMK2.AA CAMK-Unique 47-309 26 1.4e-84 279.11 In-house 1-363 (363) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-363/363
Sequence Identity: 26% (95 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQ-----------------MLYEELSILQKLSHPNIVSFKDW----FESKD------
|...| .| |.||.|. .   .|    |.|.. |.. .||..|.|                  | .|..|.....||||. . ||    |. ..      
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQT-HGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDL

---------KFYIVTQLATGGELFDRILS--------------------RGKFTE--VDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSE----
         ..|||.....||.||| |..                    .|.|.|   |.  |. ..| ||.||||...||||||.||...         
IIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNH

---------NSPLVIADFGIAKQLKGEEDL--IYKAAGSLGYVAP--------------EVLTQDGHGKPC----DIWSIGVITYTLLCGYSPFIAESVE
         |. ....|||..... . .    . .  |.. |.||              ||. ... . .|    ||||.|||.|..|||..|| .|. .
HRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECED

--------GFMEECTASRYPVTFHMPYWDN---ISIDVKRFILKALRLNPADRPTATELLDDPWI
        .  |  .. .|  .|  ..|.    ||   | |. . . . |. | .| |||. .||
RDYENHDKEIFECICKGDY-CNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CMK2.AA DCAMKL 47-309 34 7.1e-81 251.24 In-house 1-279 (279) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-279/279
Sequence Identity: 34% (99 aa)

YIFGRTLGAGSFGVVRQARKLSTN-EDVAIKI-----------------LLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLA
|  ||. | | | ||  .|. .|. .  | ||                   |... |      |   |.||.||..||.|..  . .. ... |.|  ..
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKG---KEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYV

TGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVD-KSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHG
.|| ||| | . .|||| ||. .. ..  | .|.|..|.||||.|||| | ..  .    |  .||| |.  .|.  ..|   |   |||||.|   | |
QGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYG

KPCDIWSIGVITYTLLCGYSPFIAE--SVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWI
  .|||..|||.| ||||. || ..  . |   .   .  .   | ||||||||. .|  | . |  .|  |.|| . .. ||.
CKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKF--EFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CMK2.AA RSK 50-309 31 1.3e-78 267.45 In-house 1-278 (278) Show / Hide 
Range on Protein: 50-309
Range on HMM: 1-278/278
Sequence Identity: 31% (88 aa)

GRTLGAGSFGVVRQARKL---STNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLS-HPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGK---
 . || |..| | . ||     |.   | |.| |. .  ... .    .| .||.    ||.||. .. |. ..|.|.....  |||||.... ..    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSEN-SPLVIADFGIAKQLKGE-EDLIYKAAGSLGYVAPEVLT----QDGHGKPCDIWSIG
|.| .| ... .|  |||..|.. ..||||||||.|| |.| |   ... ||| .||.. . . . ..  ... |.|||.|.    | ||.| ||.|| |
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

VITYTLLCGYSPFIA---ESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPT-----ATELLDDPWI
|. |..| |..|| .   .. .  |.     .   .. || |...| . | .| | |  .|..|..     | |....||.
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CMK2.AA Ciliate-E2 47-309 24 7.1e-78 265.02 In-house 1-365 (365) Show / Hide 
Range on Protein: 47-309
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YIFGRTLGAGSFGVVRQARKLSTNE------------------DVAIKILLKKALQGNNVQLQM----LY----------EELSILQKLSHPNIVSFKDW
|.| . .| |.||.|..... ....                   |.|||  .| .. |... ..    ..          .|..||..|.||||. ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--SKDKFYIVTQLATGGELFDRILSR-----------GKFTEVDAVEIIVQILG---------------AVEYMHSKN-VVHRDLKPENVLYVDKSEN
|.  .....|.|. .. ||.|||.| ..           ..|||  . .|. |||                |.||.|||| ..|||.||||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

SPLVIADFGIAKQLKGE-------------------------------EDLIYKAAGSLGYVAPEVLT---------QDGHGKPCDIWSIGVITYTLLCG
  . |.|||..|... .                               .....  .|..||.|||.|          | |... |||||.||| | .|.|
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YSPFIAESVEGFMEECTASRYPVTFHMP--------------YWDNISIDVKRFILK----ALRLNPADRPT-ATELLDDPWI
. ||          .      .. |  |               |...| ..| .| |     |  .|  |.| . ..|. ||.
KPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CMK2.AA Pkinase_Tyr 47-172 30 4.7e-25 85.47 Pfam 1-137 (270) Show / Hide 
Range on Protein: 47-172
Range on HMM: 1-137/270
Sequence Identity: 30% (42 aa)

YIFGRTLGAGSFGVVRQARKL----STNEDVAIKILLKKALQGNNVQ--LQMLYEELSILQKL-SHPNIVSFKDWFE-SKDK--FYIVTQLATGGELFDR
 .||..||.|.||.|....      .|. .||.|.| |   .    |  .... .|..|. .| .|||||..       ..    |||. .. .| | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

ILS----RGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDL
  .    ....|  | ... .||  . || .||| .||||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase CMK2.AA TyrKc 47-307 23 2.6e-17 57.19 SMART 1-280 (280) Show / Hide 
Range on Protein: 47-307
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKL--SHPNIVSFKDWFESK-------DKFYIVTQLATGGELFDRI
  .|..|| | ||.|....     ..||.| | . |       ......|..|. ||  .||||| .     ..       .  .||. .. .| | |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LSRGK-FTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLV-IADFGIAKQLKGE------EDLIYKAAGSLGY-------VAPEVLT
 .... ..  | ... .||    || ||||..||||   |.|. ..      | |.||| .. .. .      .| . |. .. |         |||.. 
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

QDG-HGKPCDIWSIGVI---TYTLLCGYSPFIA-----ESVEGFMEECTASRYPVTFHMPYWDNI-----SIDVKRFILKALRLNPADRPTATELLDDP
..|      |.|| ||     .|.  | .|         | .  .|   . ...   . .|   .     . .. . ...  . .|.|||| .|. .. 
NYGKFTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF