Gene CKA2 (Bakers Yeast)

CKA2

Species: Bakers Yeast
Alias: CKA2
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
CKA2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 285 Kinase domain by global Sugen HMM Fasta, JSON
CKA2.AA Protein Refseq_NP 339 may have a role in regulation and/or execution of the eukaryotic cell cycle; Cka2p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of CKA2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CKA2.AA CK2 50-334 67 3.5e-217 655.99 In-house 1-288 (288) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-288/288
Sequence Identity: 67% (193 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKC--VIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYY
||.|.|||||||||||.|..| ||.||  |||.|||||.|||.||.|||.||.||||.. |||||.|..||.|||.||...|.|||.||.|.. .||.||
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

FTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGS
...||.|||||||||||||||||.|.|||...||||||||||||||||| ||||||||||.|||||||. ..||||||.||.|||.|...|||||||.|.
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

SNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETK-LAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF
.| ||||||..||||..|. || |||.||......||....||.|..||..|.| ||.||..|..|..||||||||.||||||.|..|
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHPEAIDFLDKMLRYDHQERITAKEAMEHPYF
Kinase CKA2.AA CMGC 50-334 19 1.7e-89 294.14 In-house 1-513 (513) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-513/513
Sequence Identity: 19% (100 aa)

YEIINKIGRGKYSEVFSGRC--------------IVNNQKCVIKVLKPVKMK--------------KIYRELKILTNL----------------TGGPNV
||||.|||.| |..|...|.              . .|... || .| ....              ...||.||| .|                   .|.
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VGLYDIVQDADSKIP---------------ALIFEEIKNVDFRTLYPTFKL----------------------PDIQYYF------TQLLIALD--YCHS
|.||||... .|. .                |.|| . .  .. .. . ..                      ..|.|..       |.| .|.  ||||
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHS

MG--IMHRDVKPQNVMIDPTERK-------------------LRLIDWGLAEFYHPGVD----------------------YNVRVASRYHKGPELLVNL
..  |.||| ||.|..|... .                    |...|.||| .|||  |                      |  .|..|. . ||.|.. 
HWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGW

---------NQYDYSLDLWSVGCMLAAI-------VFKKEPFFKGSSN-----------PDQLVKIATVLG------------------TKELLGYLGKY
         ..|... | |||||..| .       .|...|.|.|.|.            ||| ||  |||                  ..|  ......
KHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIKLP

GL--------------HLPSEYDNIMRDFTKKSWTHFITSETKLAV-------------------------------------PEVVDLIDNLLRYDHQE
.               |... . |  . . .. | .... . .                                        |. .||....|.||...
WYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDK

RLTAKEAMDHKFF
|.||..|..| .|
RITAEQALQHPYF
Kinase CKA2.AA S_TKc 50-334 24 2.2e-65 224.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-231/231
Sequence Identity: 24% (75 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKN--VDFRTLYPT---------
|||..|||.| ...|. .| .  .... ||..|    ..|.||..|| .  . ||.| |||. ||   .   ...| . .   | ...            
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDY-SLDLWSVGCMLAAIV
|   ....|. |.. ||.||||.||.|||.||.|...|     . ..| ||| ..      .  . ...   ||.|    .|.. . | ||.||.|.  .
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

FKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMD-------
  . ||     ..... |.                                                ||. |.|...|..| ..|.|| ||.        
CGYPPFP----QMQMMFKKIG---------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HKFF
| .|
HPWF
Kinase CKA2.AA Pkinase 50-334 25 4.2e-65 227.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-293/293
Sequence Identity: 25% (81 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYR-------ELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNV----DFR---T-
|.|. |||.| ...|. .. . .... ..|..| .. |.  .       |..|. .| . ||.| |||...| ...|  ...|   .     |     . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIY-MVMEYCEGGLYVMDLFDYIST

-LYPTF--KLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERK---LRLIDWGLAEF--YHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDL
  . .|     ... |..|.| .|.|||||||.|||.||.|..|| .      ....|.|||..  | ... ..... ...   ||..   . |... | 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSVGCMLAAIVFKKEPFFKGS----SNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYD-NIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQE
||.||.|.  .... ||  |.    .  ||...|. ..|..          || ..... .|...|..  | || ... ... .|  |.|...|..| ..
WSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPP----------LHFDWPWWCSISYFFFRH-W-HF-HWTFHNWSEECKDFIKWCLCKDPKK

RLTAKEAMDHKFF
|.||.... |..|
RPTAEQILQHPWF
Kinase CKA2.AA CDK 50-334 25 2e-49 156.22 In-house 1-284 (284) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-284/284
Sequence Identity: 25% (87 aa)

YEIINKIGRGKYSEVFSGRCIVNN-----QKCVIKVLK-PV-----KMKKIY----RELKILTNLTGGPNVVGLYDIVQDA----------DSKIPALIF
||...|||.| | .|. .|.  ..     | . .| ..        .   .     || ..| .|   ||.| |.|.. .           ..|.  ..|
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKL-YMVF

EEIKN-----VDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTER----KLRLIDWGLAEFYH-------PGVDYNVRVASRYH
| .        |            |. |. ||| .|.|||| .||||| |||| .|. .      .| . | |||  ..       |   |  .|  .  
EYMDHDLKKYMD------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWY

KGPELLVNLNQYD--YSLDLWSVGCMLAAIVF--KKEPFFKGSSNPDQLVKIATVLGT---------KELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHF
  ||||    .|.   . |.||||| .| ..    ..|.| |.|  ||| ||  ..||         ..| .|                           
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------

ITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF
             ||....| || . |..|..|..|..|
-------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase CKA2.AA CAMK 55-243 17 4.6e-41 129.59 In-house 1-334 (425) Show / Hide 
Range on Protein: 55-243
Range on HMM: 1-334/425
Sequence Identity: 17% (58 aa)

KIGRGKYSEVFSGRCIVNN------------QKCVIKVLK-------------------------------PVKMKKIYRELKILTNLTG------GPNV
..||| ...|. .. . ..            ||. ||...                               |...|...||..|. .| |       ||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGLYDIVQD-----------ADSK--IPA------LIF---EEIKNVDF----------RTLY------------PTFKLPDIQYYFTQLLIALDYCHSM
. ||.. .|             ||  .        ...   | . . .           .. |              |.  . ..|| |.. |..||||.
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GIMHRDVKPQNVMIDPTE----------------RKLRLIDWGLAEFYHP------------------------GVDYNVRVASRYHKG-PELLVN----
.|.||| || |...|  .                 .. .||.|.| .. |                        |  .. .. . .    ||.|      
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------LNQYDYSLDLWSVGCMLAAIVFKKEPF
            |... | ||.|..| . .  . ||
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase CKA2.AA Ciliate-E2 50-334 18 2.1e-38 129.4 In-house 1-365 (365) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-365/365
Sequence Identity: 18% (74 aa)

YEIINKIGRGKYSEVFSGRCIVNNQ------------------KCV-----IKVLKPVKMKKIYRELKILT---------N------LTGGPNVVGLYDI
|..|.|||.| .. |. .. . ...                  |.      .|..|. . . | .|..|.          |      .   ||.. .|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VQDADSKIPALIFEEIKNVDFRT------LYPTFKLP--------DIQYYFTQLL---------------IALDYCHSMG-IMHRDVKPQNVMIDPTERK
 |. | .   |..| ..  | .       .  .....         |.|...|.|                || |.|| . |.||| ||.|...      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

LRLIDWGLAEFYHPGVD--------------------------------YNVRVASRYHKGPELLVNLN--------QYDYSLDLWSVGCMLAAIVFKKE
. .||.||. .|..  .                                .|  . . . . || | . .        .|||. |.||.|..|   .|.| 
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMR---DFTKKSWTHFITSETKLAV---------PEVVDLIDN----LLRYDHQERLT-
||                                    ...|.    || .. |.   |   .. .         .|. ||| .    .| .| ..|.| 
PF------------------------------------QQQIKQCKIDFPCPEWQKD-TQ-CIQ-CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITG

AKEAMDHKFF
......|..|
WEQILNHPWF
Kinase CKA2.AA CDC2 50-262 30 1.2e-32 97.21 In-house 1-227 (301) Show / Hide 
Range on Protein: 50-262
Range on HMM: 1-227/301
Sequence Identity: 30% (70 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKI-------YRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYP-----
|. |.||| | | .|. ..    || ...|  .      .        ||. .| .|   ||.| | |..     .   ..|| . . | . .       
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYL-DMDLKKYMDMSIPK

--TFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLA-EFYHPGVDYN--VRVASRYHKGPELLVNLNQYDYSLDLWSVGCM
   . .  .. |. |.| ....||...||||| ||||  || .. .... | |||  |  |   |     |  .    ||.|    .|. . |.||.|| 
NKHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILID-KKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCI

LAAI--VFKKEPFFKGSSNPDQLVKIATVLGT
.| .  .  |.|.| | |  ||| ||  .|||
FAEMFMDVTKKPLFHGDSEIDQLFKIFRILGT
Kinase CKA2.AA CDK-Unclassified 143-262 34 1e-29 94.86 In-house 122-257 (324) Show / Hide 
Range on Protein: 143-262
Range on HMM: 122-257/324
Sequence Identity: 34% (47 aa)

DIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTE----RKLRLIDWGLAEFYH-------------PGVDYNVRVASRYHKGPELLVNLNQYDYSLD
.|. ...|.|  . | |. .|||||.||||.||. .      .| ..| |.| ||              |.  | . |. |  . ||||    .||.  |
QIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQQYSTQVSTRWYRAPELLFGSKCYDTGVD

LWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT
 ||.|| .| . |.. | | | .  .|. .|  .|||
IWSFGCIYAEW-FQGKPIFQGRTEIEQMHHIFKMLGT
Kinase CKA2.AA CDK5 50-262 31 3.1e-28 85.92 In-house 1-218 (287) Show / Hide 
Range on Protein: 50-262
Range on HMM: 1-218/287
Sequence Identity: 31% (72 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKI--------YRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEI-----KNVDFRTLY
|| ..||| | |  |. .|   | .  .|  || |..            ||  .|  |   .|.| |.|..  .. |.  |.|| .     |  | ..  
YEKMEKIGEGTYGTVYKAR---NKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELK-HKNIVRLHDVIH-SEKKL-TLVFEFCDQDLKKYMDSCNG-

PTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAE-FYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAA
    .. |...  |||  | .||.  ..||| |||| .|  .. .|.| | |||  |  |   |   |       |  |    .|  | |.||.|| .| 
-EMDMHIIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLIN-KNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAE

IVFKKEPFFKGSSNPDQLVKIATVLGT
..    | | |..  ||| .|  ..||
MANAGRPLFPGNDVEDQLKRIFKIMGT
Kinase CKA2.AA RCK 150-262 33 6.5e-23 69.29 In-house 113-232 (298) Show / Hide 
Range on Protein: 150-262
Range on HMM: 113-232/298
Sequence Identity: 33% (42 aa)

QLLIALDYCHSMGIMHRDVKPQNVMIDPT--------ERKLRLIDWGLA-EFY--HPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVF
|.| .|...|. |..|||.|| | |. .            . ..| ||. |..  .|  ||   | .|.   ||.|   ..|.. .|.|.|||  . .  
QILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDY---VSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYM

KKEPFFKGSSNPDQLVKIATVLGT
.. | | |||  ||. || .|.||
LR-PLFPGSSEIDQIFKICKVMGT
Kinase CKA2.AA MAPK 203-334 28 1.2e-16 53.94 In-house 192-328 (328) Show / Hide 
Range on Protein: 203-334
Range on HMM: 192-328/328
Sequence Identity: 28% (41 aa)

VASRYHKGPELLVN--LNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGT--KELLGYLGKYGLHLPSEYDNIMRDF------TKKSW
|| |.   ||.. |  .. |. . | ||||| .|  .    |.|.|..  ||. .|  ||||  .|.. ....     .... |  . .      .||.|
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSEEFIQCICM-----SEHARNYIQSLGNLPKYPKKPW

THFITSETKLAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFF
.. .  . ..| |. .||.. .|  | ..|.|..||. | .|
EKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase CKA2.AA MAPK 50-111 30 1.4e-12 39.64 In-house 1-73 (328) Show / Hide 
Range on Protein: 50-111
Range on HMM: 1-73/328
Sequence Identity: 30% (22 aa)

YEIINKIGRGKYSEVFSGRCIV------NNQKCVIKVLK-----PVKMKKIYRELKILTNLTGGPNVVGLYDI
|.|. .|| | |  |.| ..        ...| .|| .      |. .| .|||.|.|  . . .|...|.||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDI
Kinase CKA2.AA CDC2 305-334 50 6e-11 29.34 In-house 272-301 (301) Show / Hide 
Range on Protein: 305-334
Range on HMM: 272-301/301
Sequence Identity: 50% (15 aa)

PEVVDLIDNLLRYDHQERLTAKEAMDHKFF
|| .||....|.|| | |..||||..|..|
PEGIDLLMQMLQYDPQKRISAKEALQHPYF
Kinase CKA2.AA CAMK 305-334 30 8.1e-10 27.08 In-house 396-425 (425) Show / Hide 
Range on Protein: 305-334
Range on HMM: 396-425/425
Sequence Identity: 30% (9 aa)

PEVVDLIDNLLRYDHQERLTAKEAMDHKFF
.|. ||| ..|..| ..|.|......|...
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CKA2.AA RCK 305-334 33 1.1e-09 26.58 In-house 269-298 (298) Show / Hide 
Range on Protein: 305-334
Range on HMM: 269-298/298
Sequence Identity: 33% (10 aa)

PEVVDLIDNLLRYDHQERLTAKEAMDHKFF
.. ..|.  .|..| |.| ||..|  |..|
QDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase CKA2.AA TyrKc 50-334 17 2.8e-09 -72.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 50-334
Range on HMM: 1-280/280
Sequence Identity: 17% (54 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYRELKILTNL-TGGPNVVGLYDIVQDA-----DSKIPALIFEEIKNVDFRTLY----PTF
 . . |.|.| . ||. |. .   ... .|.||. ... ..||..|...|    ||.| || .. .       .. . ...|  .. | .       |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

KLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPG-------VDYNVRV--ASR-----YHKGPELLVNLNQYDYSLD
...|  .. .|     .| ||... |||    |....      .  | ||. . . .         | ..    ..         || . | . .    |
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSD

LWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEY----DNIMRDFTKKSWTHFITSETKLAVPEVVDLIDNLLRYDHQE
 || | ..       | |  | . .   ..   ..  .|.. |. . .   . ..                  |       . .|. ...    ..|  .
VWSFGVCMW------EIFTYGQQPYPGMIQQ--MMSNQEVIEYVKQGYRMPQPPNDYPMS-------------F-----VCCPDEMYQIMKQCWHEDPED

RLTAKEAMDHKFF
| | .|   |..|
RPTFSEI--HECF
Kinase CKA2.AA CDK5 309-334 34 8.9e-09 23.36 In-house 262-287 (287) Show / Hide 
Range on Protein: 309-334
Range on HMM: 262-287/287
Sequence Identity: 34% (9 aa)

DLIDNLLRYDHQERLTAKEAMDHKFF
||  ..|... ..|..||.|. | .|
DLLQKMLQCNPNQRISAKAALHHPYF
Kinase CKA2.AA RCK 50-125 28 2e-07 19.29 In-house 1-80 (298) Show / Hide 
Range on Protein: 50-125
Range on HMM: 1-80/298
Sequence Identity: 28% (23 aa)

YEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKI-----YRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFE
| ||...|.| |..|. .. . ....  || .|  | ...      ||.| |  |.  ||.. |.....| |. . ...||
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMK-QKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFE
Kinase CKA2.AA MAPK 144-176 42 2e-06 18.29 In-house 117-151 (328) Show / Hide 
Range on Protein: 144-176
Range on HMM: 117-151/328
Sequence Identity: 42% (15 aa)

IQYYFTQLLIA--LDYCHSMGIMHRDVKPQNVMID
||| . |.| .  | | ||... ||| || |. ..
IQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVN
Kinase CKA2.AA APH 162-198 37 0.000108 16.88 Pfam 171-210 (248) Show / Hide 
Range on Protein: 162-198
Range on HMM: 171-210/248
Sequence Identity: 37% (15 aa)

GIMHRDVKPQNVMIDPTERKLR---LIDWGLAEFYHPGVD
...|.|..| |||.|| ... |   .|||. | . .|  |
CWCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWGDPHYD
Kinase CKA2.AA Pkinase_Tyr 50-99 25 0.000148 16.05 Pfam 1-60 (270) Show / Hide 
Range on Protein: 50-99
Range on HMM: 1-60/270
Sequence Identity: 25% (15 aa)

YEIINKIGRGKYSEVFSGRCI----VNNQKCVIKVLKPVKMKK------IYRELKILTNL
 ... |.|.| . ||. |..      ..... .|.||.  |..        ||.||...|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQL
Kinase CKA2.AA CDK-Unclassified 309-334 19 0.002035 6.95 In-house 299-324 (324) Show / Hide 
Range on Protein: 309-334
Range on HMM: 299-324/324
Sequence Identity: 19% (5 aa)

DLIDNLLRYDHQERLTAKEAMDHKFF
... ... |.  .|... |.  |  |
NCEFQMVMYQPYNRWKCMEILQHPWF
Kinase CKA2.AA CDK-Unclassified 50-68 26 0.008299 4.91 In-house 1-19 (324) Show / Hide 
Range on Protein: 50-68
Range on HMM: 1-19/324
Sequence Identity: 26% (5 aa)

YEIINKIGRGKYSEVFSGR
|... |.|.| . .|. ..
YRMQCKYGEGTFGCVCKAI