Gene zyg-1 (Nematode worm)

zyg-1

Species: Nematode worm
Alias: CE28571, aSWK253, F59E12.2, zyg-1
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-1.27084, WormBase Physical Map location: II: 5649703-5654388,

Classification

Group: Other
Family: PLK
Subfamily: SAK

Sequence

Name Sequence Type Origin Length Description Download
zyg-1.AA Protein Genbank 706 None Fasta, JSON
zyg-1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of zyg-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc zyg-1.AA S_TKc 13-249 28 1.8e-69 237.99 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-249
Range on HMM: 1-231/231
Sequence Identity: 28% (74 aa)

YSHLKEIGKGGFGVVYAAQREN-GEKVAIKRIDKKVPKNRVWTEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEG--GSLQAYVREHGA------L
|  |..||||.||.|| ..  . |..||||.|.     .... ||| .|.  . ...| .|. |.. .. |.|||.|.|  |.|  | ...|       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGRGETTCTIVGTPGFIAPQVYDQEYTQ-SADVYSLGAVLYTML
.  .| ....|...|. ..|. ..|||||   |... .      ..|..|||||. |       |..||| ..|| |    |.  ..|..|.| .|| ||
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEML

TARNPPPKGLPPT----CGMSPNAARLVEQMMDTDAKKRIPLTQIVL-------SEFM
. . | |   . .    .| || |  ....... | .||.   ..          ...
CGYPPFP--QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase zyg-1.AA Pkinase 13-209 32 7.2e-59 206.69 Pfam 1-213 (293) Show / Hide 
Range on Protein: 13-209
Range on HMM: 1-213/293
Sequence Identity: 32% (71 aa)

YSHLKEIGKGGFGVVYAAQRENGEK-VAIKRIDKKVPKNRVW------TEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEGG----SLQAYVR--E
|  .. ||.|.||.|| ... . .| ||.|.|.|.  |  ..      .||| ||.| .....|..|. | .... |.|||.||||    .| .|..  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HGAL--DDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATT--LGRGETTCTIVGTPGFIAPQV--YDQEYTQSADVYS
||..  .. .. ....|..... ..|. ..|||||   |..|..    . .||..|||||    . ... . |..|||...|| |   .|.|....|..|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGAVLYTMLTARNPPP
.| .|| ||. | | |
CGCILYEMLCGRPPFP
Kinase zyg-1.AA CAMK 18-207 21 7.2e-57 181.43 In-house 1-333 (425) Show / Hide 
Range on Protein: 18-207
Range on HMM: 1-333/425
Sequence Identity: 21% (72 aa)

EIGKGGFGVVYAAQRE-NG------------EKVAIKRIDKK------------------------------VPKNRVWTEIQTMKELKK------SKYV
..|.|.||.|. ...  ..            .||||| ||||                              . . .|  ||. || |..       . .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEFYEDFV--------EDGY------------TYIVM---ELCEGG----SLQAYVREH---------------GALDDATAVHVLRQLISAVSFMHRVN
. .|| .          | |             |.||   |.|.||     |  |..||               | .. . | .. ||..||| ..|  |
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDLSAGNVFIKDSKKKK-------------MTVKLGDFGLATTLGR------------------------GETTCTIVGTPGFIA-PQVYDQE----
..||||   |. . |... .              ..|. |||.|. . .                        |.   | .|||...| | |  ..    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YTQSADVYSLGAVLYTMLTARNP
           |....|. |.| .||.||. . |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP
Kinase zyg-1.AA CAMKL 13-249 26 1.9e-56 178.56 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-249
Range on HMM: 1-297/297
Sequence Identity: 26% (80 aa)

YSHLKEIGKGGFGVVYAAQR-EN-GEKVAIKRIDKKVPKN-----------------RVWTEIQTMKELK--KSKYVVEFYEDFVEDGY------TYIVM
|  .|..|||.||.|  |.   . ||||||| ||||  .|                 |.  ||| || |.  | . .. .|| .  . .       |.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCEGGS--LQAYVREHGA----LDDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGR-----GETTCTIVGTPG
|.|.||.  |. |...||     ..   | .  ||..|||...|. ...|||. . |. . ....   ..|. |||...   .     |..  |  |.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPP

FIAPQVYDQ--E-YT-QSADVYSLGAVLYTMLTARNP----------------------PPKGLPPTCGMSPNAARLVEQMMDTDAKKRIPLTQIVLSEF
. || ..    . |  . .|. |.| .||.|.. . |                        .  |. . .|  . .|  .|. .. .||. . ||.  ..
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

M
|
M
Kinase zyg-1.AA ULK 13-249 24 2.4e-55 190.17 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-249
Range on HMM: 1-329/329
Sequence Identity: 24% (82 aa)

YSHLKEIGKGGFGVVYAA--QREN---GEKVAIKRIDKK--VPKN----------RVWTEIQTMKELK---KSKY----VVEFYEDFVED--GYTYIVME
|.  ...||| ||.|| .  .. .   .||||.| |||.    ||           .  ||..||.||   ..|.    .|..|. | ..   ..||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCEGGSLQAYVREHGALDDAT----------AVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKK--------KMTVKLGDFGLATTLGRG-----
.|.|| |. |  ... |   |          |.....|....  ..|  |.||||.   |. |.. . |        ....|..|||.| ..  .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-ETTCT----IVGTPGFIAPQVYDQE-----YTQS-ADVYSLGAVLYTMLTARNP----PPKGL----------PPTCG------------------MSP
 ..||.    . ||| . |||.  ..     |. . .|..||| ..| ||. . |    . .            ||...                   ||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

NAARLVEQMMDTDAKKRIPLTQIVLSEFM
.   |  .|.  | |.||  ...   ...
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase zyg-1.AA ULK 13-208 28 2.8e-54 186.66 In-house 1-252 (324) Show / Hide 
Range on Protein: 13-208
Range on HMM: 1-252/324
Sequence Identity: 28% (71 aa)

YSHLKEIGKGGFG-VVYAA--QREN--GEKVAIKRID----KKVPKN--------RVWTEIQTMKELK--KSKY--VVEFYEDFVED--GYTYIVMELCE
|.  ...||| || .|| .  .. |  ...||.| ||    .| ...            |||.||.||  |...  .|..|. | ..   ..||.||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLQAYVREHGALDDAT----------AVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKK--------KMTVKLGDFGLATTLG---RGETTC-
|| |. |  ... |   |          |.....|....  ..|  |.||||.   |  |.. . |        . ..|..|||.| ..      .. | 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TIV------GTPGFIAPQVYDQE-----YTQS-ADVYSLGAVLYTMLTARNPP
|.|      ||| . |||.  ..     |. . .|..||| ..| ||. . |.
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF
Kinase zyg-1.AA STE 13-249 19 8.9e-48 165.04 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-249
Range on HMM: 1-359/359
Sequence Identity: 19% (71 aa)

YSHLKEIGKGGFGVVYAAQREN----------------GEKVAIKRIDKKVP-------------------KNRVWTEIQTMKELKK-SKYVVEFYEDFV
. ....||||.||.|| | . .                || .|||.....                     ....  ||..||.... ....|..|  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EDG-------YTYIVMELCEGGSLQAYVR-EHGALD-------------DATAVHVLRQLISA-VSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDF
 .|       . .|.||...||||   ..  .| ..                  ...||.. .  .. |. ..||||. ..|...         ||| ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDF

GLATTLGR-----------------GETTCTIVGTPGFIAPQVYDQE-------YTQSADVYSLGAVL-------------YTM----LTARN-------
|... |                   .. . |.|||| . || | .|.       |. ..|..||| ..             . |    ....|       
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

-------PPPKGLPP-----------------TCGMSPNAARLVEQMMDTDAKKRIPLTQIVL--SEFM
       .||  ||.                 .  .||.    ...  . | .||   .|      .| 
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase zyg-1.AA Ciliate-E2 13-207 21 9.9e-48 161.92 In-house 1-295 (365) Show / Hide 
Range on Protein: 13-207
Range on HMM: 1-295/365
Sequence Identity: 21% (64 aa)

YSHLKEIGKGGFGVVYAAQR-ENGE------------------KVAIKRIDKKVPKNR----VWTEIQTMKELK---------------KSKYVVEFYED
|  .| ||.|.||.|| ... ....                  ||.|| . .|. |..    .  ||. |.|..               ........|| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FV--EDGYTYIVMELCEGGSLQAYVREH-----------GALDDATAVHVLRQLIS---------------AVSFMHRVN-VIHRDLSAGNVFIKDSKKK
|    | . |.|||.|.||.|. | ...           . ...  . .. .|...               |. ..|  | .||||.   |...      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

KMTVKLGDFGLATTLG-----------RG---------------------ETTCTIVGTPGFIAPQVYD----------QEYTQSADVYSLGAVLYTMLT
   .|. ||||.. .            ..                     ... ||.||||. ||...           ..|. ..|..||| .|| ||.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

ARNP
 . |
GKPP
Kinase zyg-1.AA Ciliate-E2a 13-203 29 6.4e-46 133.16 In-house 1-211 (275) Show / Hide 
Range on Protein: 13-203
Range on HMM: 1-211/275
Sequence Identity: 29% (63 aa)

YSHLKEIGKGGFGVVY-AAQRENGEKVAIKRIDKKVPKNR-----VWTEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREHGALDDA
|. .|.|||| ||.|| | ....|.. |.| ..||   .      .  ||. |..| . . .  .|| .  . . |.|||.||||.|  . .... ..  
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL-DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--TAVHVLRQLIS-AVSFMHRVNVIHRDLSAGNVFIKD-SKKK--KMTVKLGDFGLATTL--GRGETTCTIVGTPGFIA------PQV-YDQEYTQSADV
   . ....||.. ... ||  |..||||   |...|. ||..  .  .|. ||||||      ..   ...||||..|      ..|  .. |... |.
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDM

YSLGAVLYTMLT
 |.|...|..|.
WSCGVIFYILLC
Kinase zyg-1.AA Ciliate-E2-Unclassified 13-207 22 2.3e-43 148.3 In-house 1-269 (352) Show / Hide 
Range on Protein: 13-207
Range on HMM: 1-269/352
Sequence Identity: 22% (61 aa)

YSHLKEIGKGGFGVVYAAQRENGEKV-----AIKRIDKK-----VPKNRVWTEIQTMKELK------------------KSKYVVEFYEDFVEDGYTYIV
|  .| ||.||||.|| .|...  ..     ..| ...|       . . . |...|...|                  .. ..| ... |  . . |||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MELCEGGSLQAYVREHGA-----------------LDDATAV-----HVLRQLISAVSFMHRVN-VIHRDLSAGNVFIKDSKKKKMTVKLGDFGLAT---
||.||||.|. | .. .                  ...  |.     . ..|.... ...|. | .||||.   |.......| .  .|. |||..    
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKKYQ

-----TLGRG---------ETTCTIVGTPGFI----APQVYDQ-EYTQS----ADVYSLGAVLYTMLTARNP
     . ...         . ..|..|||...    || |... .| .|    .|..||| .|| ||. . |
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase zyg-1.AA RSK 16-203 25 1.5e-39 137.75 In-house 1-207 (278) Show / Hide 
Range on Protein: 16-203
Range on HMM: 1-207/278
Sequence Identity: 25% (54 aa)

LKEIGKGGFGVVYAAQRE----NGEKVAIKRIDKKVPKNR------VWTEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREHGA---
||. |.||.| |.  ..     .|   | | ..|.. ..|      ..||.. ... .... .|. .. | ..|..|..||.|.|| |    ....    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATT-LGR-GETTCTIVGTPGFIAPQVYD----QE-YTQSADVYSLG
..  .|  .......||...|   .|||||   |.   | .    ..|| |||..     . .. | | ..|  ..|| .      |. .....|..|||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLG

AVLYTMLT
...|.|||
VLMYEMLT
Kinase zyg-1.AA TKL 19-247 19 7.7e-39 135.36 In-house 1-364 (364) Show / Hide 
Range on Protein: 19-247
Range on HMM: 1-364/364
Sequence Identity: 19% (71 aa)

IGKGGFGVVYAAQREN---------GEKVAIKRIDKKVPKNRVW--------------------------TEIQTMKELKK--SKYVVEFYE--------
||.||||.|| ..  .         |. ||.|.. ..  ... .                          .|.. .. ...     .| |.         
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-DFVE----DGYTYIVMELCEGGSLQAYVREHGALDDATAVHVLRQLISAVSFMHR--------VNVIHRDLSAGNVFIKDSKK----------KKMTVK
   ..    .|. .||||.|.||||  |.           ..  ..  ......|          ..|||||   |.....  .          .  ..|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LGDFGLATTL--------------------GRGETTCTIVGTPGFIAPQV------YDQ-----------EYTQSADVYSLGAVLYTMLTARNPPP----
..||||....                     ...||.|..|||.. || |      |..           ||....|||| | ||. .|| . |      
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

------------------KGLPPTCG--------------MSPNAARLVEQMMDTDAKKRIPLTQIVLSE
                  |||.|..               . |  ..| .. .|.|..||   ..|.   
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase zyg-1.AA Pkinase_Tyr 13-157 26 2.1e-25 86.65 Pfam 1-158 (270) Show / Hide 
Range on Protein: 13-157
Range on HMM: 1-158/270
Sequence Identity: 26% (43 aa)

YSHLKEIGKGGFGVVYAAQRE-----NGEKVAIKRI--DKKVP---KNRVWTEIQTMKELKKSKYVVEFYEDFV-EDGY--TYIVMELCEGGSLQAYVRE
 . .|..|.| ||.|| .        .. .||.| .  .   .   .     |...||.| . . .| .|   . ...    |||||....|.|  | |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H----GALDDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLA
|    ..|.  . ..  .|  .. .. .. | ||||| | |. ...    ...|| .|||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLA
Kinase zyg-1.AA TyrKc 13-248 20 2.1e-14 10.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-248
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YSHLKEIGKGGFGVVYAAQRENGEKVAIKRIDKKVPKNRVWTEIQTMKEL-KKSKYVVEFYEDFVED-------GYTYIVMELCEGGSLQAYVREHGA-L
 . .|..| | ||.|| ..    ..||.| . .   .     |.. |..| .. . .| .|   ...       .  .||||....|.|. | |.|.  |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

DDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGRG-------ETTCTIV--GTPG-----FIAPQVY-DQEYTQS
  .. ..   |  .  .. |. |.||||| | |. ... .    ||| .||||.  .. .       ..  .    |. .       || .  . ..|  
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

ADVYSLGAVLYTMLTARNPPPKG--------------------LPPTCG--------MSPNAARLVEQMMDTDAKKRIPLTQIVLSEF
 ||.| | ... ..|   .|. |                    .|.           ...   .. .|  . |...|   ..|  ..|
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase zyg-1.AA CAMK 219-249 25 0.000372 8.5 In-house 395-425 (425) Show / Hide 
Range on Protein: 219-249
Range on HMM: 395-425/425
Sequence Identity: 25% (8 aa)

SPNAARLVEQMMDTDAKKRIPLTQIVLSEFM
|. .  |. .|. .| .||. ..|.   ..|
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase zyg-1.AA Ciliate-E2a 219-249 29 0.123638 0.61 In-house 245-275 (275) Show / Hide 
Range on Protein: 219-249
Range on HMM: 245-275/275
Sequence Identity: 29% (9 aa)

SPNAARLVEQMMDTDAKKRIPLTQIVLSEFM
| ..  |. .| . | ||||  .|.  . ..
SKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase zyg-1.AA Pkinase 218-249 21 0.151321 6.55 Pfam 262-293 (293) Show / Hide 
Range on Protein: 218-249
Range on HMM: 262-293/293
Sequence Identity: 21% (7 aa)

MSPNAARLVEQMMDTDAKKRIPLTQIVLSEFM
.|...  ... . . | |||.  .||. ....
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase zyg-1.AA Ciliate-E2 219-249 25 0.155906 1.01 In-house 330-365 (365) Show / Hide 
Range on Protein: 219-249
Range on HMM: 330-365/365
Sequence Identity: 25% (9 aa)

SPNAARLVEQ----MMDTDAKKRIP-LTQIVLSEFM
|...  |  .    |.. | .|||    ||   ...
SQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF