Gene ZK622.1 (Nematode worm)

ZK622.1

Species: Nematode worm
Alias: ZK622.1, aSWK362, CE05098
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-1.7, WormBase Physical Map location: II: 5293921-5295561

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
ZK622.1.AA Protein Genbank 419 None Fasta, JSON
ZK622.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of ZK622.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 ZK622.1.AA SH2 30-113 38 1.3e-23 85.66 SMART 1-87 (87) Show / Hide 
Range on Protein: 30-113
Range on HMM: 1-87/87
Sequence Identity: 38% (35 aa)

MDWYHGLLPRADINTLLEN----DGDFLVRTSHIVGQDSAKTVLSVKWKGKCHHWQLQEKEDGSIVIEE---RKFESVLDMVTTLRMKRLP
. |||| ..|..   || |    ||||||| |     .  . ||||.||||..| ......||. .|.|   |||.|. ..|   .  .|.
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 ZK622.1.AA SH2 32-107 31 4.1e-16 49.14 Pfam 1-81 (81) Show / Hide 
Range on Protein: 32-107
Range on HMM: 1-81/81
Sequence Identity: 31% (27 aa)

WYHGLLPRADINTLLEN----DGDFLVRTSH-IVGQDSAKTVLSVKWKG---KCHHWQLQEKEDG-SIVIEERKFESVLDMVTTL
|||| ..|..   || |    ||.|||| |    |.     .|||...|   . .| . |. ..|   .....||.|. ..|   
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD----YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase ZK622.1.AA Fer 138-399 49 1.3e-153 516.66 In-house 1-283 (283) Show / Hide 
Range on Protein: 138-399
Range on HMM: 1-283/283
Sequence Identity: 49% (139 aa)

IKLGKMLGEGAFGGVYKA--AFYCKGEKRMV----AVKVNKGNEKISTRAMIEDVCKEARIMRQ-YQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFL
..|||.||||||| |||.  ...|| .|..|    ||||.| ..  .|...|.....||||||. |.|||||.|.|||| ..|||.|||....|.|||.|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KNEKN-NVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHK-NVVK---ITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSD
| .|| .||...|......|..|.||||...|||||.|||| |.|| .|.|   |.|||.|.|.||  ..||.|... |.||||||||.. | .|..|.|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VYSFGILLWEIFMDGAIPYPG----MKLAEV-----KQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAME
|.|||...||||..|| ||||    ||...|     |...|.||.|  |..|| ....|| .|||...|||| .|.||.  ..
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase ZK622.1.AA TyrKc 138-398 40 3.5e-123 416.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-280/280
Sequence Identity: 40% (118 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQY--QHPNVVCFFGVCVEK-------EPIMLVMELASQGALDS
|.|||.||||||| |||.  .     ..||||. | .        .|| ..|||||...  .|||.|...|||...       ||.|.|||... |.|..
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FLKNEKNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHKNV-VKITDFGLSKQLSDL-----AHKYKLKD--IQAK--LPIRWLAPEVIVTA
.|.. .......|.|........| ||||...||||| |||| | ..|  |||.|||||. . |      ...|. |    ..|  |||||.|||.| . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

TYTFKSDVYSFGILLWEIFMDGAIPYPG-----MKLAEVKQKVKNGYRMDAPDR--------MPAFVRNIMISQCWPQNPEDRGNMNEIRLAM
..|.||||.|||...|||| .|. ||||     |. .|| ..||.||||. |.         .|. . . ...|||  .|||| ...||.  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase ZK622.1.AA Pkinase_Tyr 138-398 42 7.89999999999e-103 348.88 Pfam 1-270 (270) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-270/270
Sequence Identity: 42% (116 aa)

IKLGKMLGEGAFGGVYKAAFY--CKGEKRMVAVKVNKGNEKISTRAM--IEDVCKEARIMRQY-QHPNVVCFFGVCV-EKEP--IMLVMELASQGALDSF
|..||.||||||| |||.  .   ...|  ||||. |     ..     .||  .||.||.|. .|||.|.. |||. ..||  |..|||..  | |...
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LKNE---KNNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMH-KNVVKITDFGLSKQLSDLAHKYK-LKDIQAKLPIRWLAPEVIVTATYTFKS
|..    |..... |.|..... .||.|||....|||||.|||| | . .|||||.||||.. .      |   |   .||||.|.|||.| .  .| ||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DVYSFGILLWEIFMDGAIP-YPGMKLAEVKQKV-KNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAM
||.|||.|.||||  |..| ||||. .||.... ..||||..|.  |. . .. . ||| ..||||  . ||.  .
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase ZK622.1.AA TK 138-398 22 2.4e-99 333.76 In-house 1-486 (486) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-486/486
Sequence Identity: 22% (108 aa)

IKLGKMLGEGAFG---GVYKA-------------------AFYCKG----EKRMVAVKVNKGNEKISTRAMIEDVCK----------EARIMRQYQ----
|.||| ||||.||    |||.                    ..||.    .|  ||||. |     | .........          ||..| . .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVVCFFGVCVEK------------EPIMLVMELASQGA----LDSFLKNEKNN--------------------------------------------
 |||.| ..|||...            ||.|.|||... |     |...|.. ...                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VSLRDKLKYSFDASKGLEYLHQH------GCIHRDVAARNFLMHKN------------VVKITDFGLSK
                               ......| .......|.||||..      ...|||.|||| | ..|            |.||.|||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

Q----LSDLA--------------------------HKYKLKDIQAKLPIRWLAPEVIV---------TATYTFKSDVYSFGILLWEIFMDGAIPYPG-M
|    |.                             ..|.... ..||||||.|||..          . ..| ||||.|||.|.||||. |. ||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

KL---------AEVKQKVKNG--------------YRMDAPDRMPA-------------FVRNIMISQCWPQNPEDRGNMNEIRLAM
           .|| .....|              .|| .|. .|               .  ... |||  .|||| .. ... ..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ZK622.1.AA UTK 138-398 35 2.2e-89 303.25 In-house 1-296 (296) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-296/296
Sequence Identity: 35% (106 aa)

IKLGKMLGEGAFGGVYKAAF-YCK--GEKRMVAVKVNKGNEKISTRAMI--EDVCKEAR---IMRQYQ-HPNVVCFFGVCVEKEPIMLVMELASQGALDS
..||. ||.|||| |.|| |  |.  ...  |||||.. ... .....    |. .|||   .| | . ||||. . |||.  ||.|.|.|....| |.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

FLKNEKNN-------VSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHKN--------VVKITDFG---LSKQLS-------DLAHKYKLKDIQA
.| . . .       ..|...|... | . |..|||..|..|||.||||.| |..        |.|| |||   .|....       .    |  .. | 
YLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQD

KLPIRWLAPEVIVTA-TYTFKSDVYSFGILLWEIFMDGAIPYPGMKLAEVKQKVKNG--YRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAM
..|||| |||... . ..|.||||.|||...|||.. |. |||||  ..| . | ||  ||| .|...|. | ..|  .|| ..|..| .. ... .|
RWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMH-RCWHYDPQERPDFEDLVQQM
Kinase ZK622.1.AA TK-Unique 138-398 32 3.4e-73 249.47 In-house 1-294 (294) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-294/294
Sequence Identity: 32% (96 aa)

IKLGKMLGEGAFGGVYKAAFYCKG---EKR-MVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQ-HPNVVCFFGVCVEK-EPIMLVMELASQGALDSFLK
...|. .|||||| |... .  .    .|.  |||| .| |.   ...   |  ||...|..   |||.| ..|.|... || |..|| ...| |...|.
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQ---DFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLR

NEKNN-------------------------VSLRDKLKYSFDASKGLEYLHQ--HGCIHRDVAARN-FLMHKNVVKITDFGLSKQLSDLAHKYKLKDIQA
. . .                         .|..| . . ..  .|.|||..  ....|||..||| .| ...|.||.|||... ...  ..|  .. | 
TCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQG

KLPIRWLAPEVIV--TATY-TFKSDVYSFGILLWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRM-PAFVRNIMISQCWPQNPEDRGNMNEIRLAM
..||||.|||..   . .| | ||||.|||.|.||||  || |||||. ... .....||||. |.   .  ..|.|.| ||  .||.|..  .|.   
RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS-CWQWEPEERPSFRQIKHRL
Kinase ZK622.1.AA SFK-Src 138-402 36 4e-67 197.76 In-house 1-259 (259) Show / Hide 
Range on Protein: 138-402
Range on HMM: 1-259/259
Sequence Identity: 36% (98 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLKN-EKNN
|.| | ||.| || |.|     . |   ||||  |     .     |   .|| .|.. .||| .  . ||  .|||  . ||   | |  .|.. .   
IRLEKKLGSGQFGDVWKGRWNNTTE---VAVKTLK-----PGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRS

VSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLM-HKNVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWE
  .        .   |. ||     .||| |||| |    ||.|. |||.|  | .    |  ..  || ||.| |||   . ..  |||| |||||. |
LRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEG-AKFPIKWTAPEAMNMNRFSIKSDVWSFGILMME

IFMDGAIPYPGMKLAEVKQKVKN--GYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAMESVL
|   | ||||||  .|| |.|    ||||..|   |    .||. .|| ..|.||      .  ||   
IVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMF-DCWQHEPDDRPTFESLKWQMEDFF
Kinase ZK622.1.AA Src 138-388 39 2.3e-66 224.45 In-house 1-245 (255) Show / Hide 
Range on Protein: 138-388
Range on HMM: 1-245/255
Sequence Identity: 39% (100 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLK--NEKN
||| . ||.| || |... .  . .   ||||. |     |. |      .|| || . .|...|  . || ..|||  | |. |.| |  .||   |  
IKLCRKLGQGQFGEVWMGYWNGNTK---VAVKTLKPGT-MSPEAFL----QEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

NVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLM-HKNVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLW
...|.. .  .   ..| .|| .   |||| |||| |  ..||.|. |||| . . .    |  .   ||.||.| ||| |   ..| |||| ||||||.
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARH-GAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDR
||.  | .|||||. .|| |.|..||||  |.  |. . .. . ||| . ||.|
EIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQR
Kinase ZK622.1.AA EGFR 138-399 33 3.1e-60 198.63 In-house 1-258 (258) Show / Hide 
Range on Protein: 138-399
Range on HMM: 1-258/258
Sequence Identity: 33% (87 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLKNEKNNV
.|..| || |||| |||  .. .||.  . | . |  .. . .   |..  || .|   .||..|   |||.... ..||  .   |.|  .... |.|.
LKKVKVLGSGAFGTVYKGIWIPEGENVKIPVAI-KVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQHKDNI

SLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHK-NVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWEI
  .. | ...   ||..|| .|  .||| |||| |. . | ||||||||.| |.  . .|. ..  .|.||.|.| |.|    || .||| |.|. .||.
GSQHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQG--GKMPIKWMALECIHHRCYTHQSDVWSYGVTCWEL

FMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAME
   |. || |....|. . ...| |.  |.     |  .|. .||   .. |    |.   ..
MTFGQKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMVMV-KCWMIDEDMRPTFKELYEEFK
Kinase ZK622.1.AA Frk 138-402 35 2.6e-57 196.73 In-house 1-260 (260) Show / Hide 
Range on Protein: 138-402
Range on HMM: 1-260/260
Sequence Identity: 35% (95 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLK---NEK
|.| . || | || |.   .     .  ||||  |     .  .  .|  .||.||.. .|| ..  . ||  .|||... ||  .|.|  .|.   .. 
IQLIRRLGSGQFGEVWEGLWN---NTTPVAVKTLK-----PGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKG

NNVSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLM-HKNVVKITDFGLSK-QLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGIL
... ..  .  .     |. || ..  ||||.|||| |.  .|..|| |||| .  . |    |  .  .|..||.| ||| . .  .| ||||.|||||
RQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESR-HGARFPIKWTAPEAANYNKFTIKSDVWSFGIL

LWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAMESVL
| ||   | .|||||  ||| | |..||||  |   |  . .||. .|| ..|. |     ..  .|  .
LTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIML-ECWHSDPMKRPTFETLQWKLEDYF
Kinase ZK622.1.AA ALK 138-388 38 1.4e-56 193.78 In-house 1-261 (273) Show / Hide 
Range on Protein: 138-388
Range on HMM: 1-261/273
Sequence Identity: 38% (101 aa)

IKLGKMLGEGAFGGVYKAAFYC-KGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLKNEKNN
|.|.. || |||| || . .    |     .|..    |  | ..  || |.|| || ...|.|||   |.| .| | | | |. . | . |||.   ..
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCS-QQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPH

VS--------LRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHKN----VVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKS
 .         .| |.   |  .|  ||   . ||||.|||| |        |.|| ||| ..     |  |  |  .| .|. |  ||      .| |.
PESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYR-KGGRAMMPVKWMPPEAFMDGIFTSKT

DVYSFGILLWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDR
|| |||.|.||||  | .||||..  || . |  | ||| |   |  | .|| .|||   ||||
DVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIM-TQCWQHQPEDR
Kinase ZK622.1.AA Src-Echino1 138-398 34 2e-56 193.77 In-house 1-252 (252) Show / Hide 
Range on Protein: 138-398
Range on HMM: 1-252/252
Sequence Identity: 34% (92 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQGALDSFLKNEKNN-
 .. | .|.| .| |.|  .    .   ||||  | .  .|  ...     || .|.. .| ..| .. || .|||| .| || |.| | ..||..|   
LRMDKKIGKGHCGEVWKGVWNGNTP---VAVKTLKEKT-MSPADFLA----EANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKH

VSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHK-NVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFGILLWE
| .   .    .   |..|| .   .|||.|||| |. | ||.|| |||| . . .  .  |     |||||.| ||| ..   .| ||||.|||||. |
VKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ---GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTE

IFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRLAM
.   | .|||||.  || ..|..||||  ... |  . .... .|| ..|  |  .. .   .
MVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase ZK622.1.AA S_TKc 138-402 25 4.7e-49 170.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 138-402
Range on HMM: 1-231/231
Sequence Identity: 25% (70 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQ--GALDSFLKNEKN
 .... .|.|||| |||.  . |. .| ||.|. |           |....| .|... .|||.| ...|... . . .|||....  | | ...|. . 
YEILRKIGKGAFGKVYKC--RHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

N-----VSLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMHKNVVKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTF-KSDVYSF
.      .  .  .|     ..|||.|.|| ||||.   | |. . ..||.||||..||                   ..||||.    |.. |.|..|.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GILLWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIRL-----AMESVL
|..|.| .  |  |.|   .... .|..           .  ... .|..|.  .||.|    |.       ..   .
GCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ZK622.1.AA Pkinase 138-337 29 8.2e-37 131.25 Pfam 1-206 (293) Show / Hide 
Range on Protein: 138-337
Range on HMM: 1-206/293
Sequence Identity: 29% (64 aa)

IKLGKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCK------EARIMRQYQHPNVVCFFGVCVEKEPIMLVMELASQG----ALD
...|. .|.|.|| |||.  . ||. ..||||.      |. |   .....      |..||.  .|||.| ..... .|  | .|||..  |     | 
YHIGRKIGSGSFGCVYKC--HHKGTGKIVAVKI------IKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

SFLK-NEKNNV--SLRDKLKYSFDASKGLEYLHQHGCIHRDVAARNFLMH-KNVV----KITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIV-TA
....  .....  | ..  .|     .||||.|..|.||||.   |.|.. ....    ||.||||.||.. . ..  ....     ....|||||    
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCG--TPWYMAPEVIRGGQ

TYTFKSDVYSFGILLWEIF
 |. |.|..|.|..|.| .
YYGPKVDMWSCGCILYEML