Gene ZK507.3 (Nematode worm)

ZK507.3

Species: Nematode worm
Alias: aSWK113, ZK507.3, CE24728, YOO1_CAEEL, ZK507.2+, ZK507.2+and.3new
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:0.17, WormBase Physical Map location: III: 9096808-9098536

Classification

Group: CK1
Family: CK1-Unique

Sequence

Name Sequence Type Origin Length Description Download
ZK507.3.AA Protein Genbank 373 None Fasta, JSON
ZK507.3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 237 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of ZK507.3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZK507.3.AA CK1-Unique 25-265 33 6.8e-130 437.82 In-house 1-337 (337) Show / Hide 
Range on Protein: 25-265
Range on HMM: 1-337/337
Sequence Identity: 33% (114 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCK--EHFPELIDFGQSPVWKWIVMTIVGPSLEELK
|.||...|.||||.|..||.||...|.|||..|.|||||.|..||..||.||||||....||..|||  .||.|..||.|...|.|||||..|||.||..
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC

MKYKPSDIPPS------TILQCGLQT----------------MKPITVSAMDPK-AKQFMYSILDSPES----IVSPNGQVRPPRPKTKMIGTPRYCSRA
|..|.......      ...|||.|.                |||.....|.|. ..|..|..||....    .||.|.|.|.|||.|...|...||...
MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCS

SHRCEELGRRDDYESWFFMFIDLVDTT-------------------------------------------------------LIDWKGLTRPDAYAKKQE
.|.|.|.|||||.||||.|...||..|                                                       ...||||.|..||.|...
CHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKLDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDEKMCWKGLRRQNAYDKHKN

------------LFTKLKTYEKEPMFKVISIYLDTLV
            ||.|.|......|....|.|..   
YQNSKQFNEKPCLFCKIKPHNDMKMYCCMSEYFYMFN
Kinase ZK507.3.AA CK1 25-146 22 1.3e-28 96.92 In-house 1-145 (339) Show / Hide 
Range on Protein: 25-146
Range on HMM: 1-145/339
Sequence Identity: 22% (32 aa)

WKVIVELGKGGYG-TVNKVIK---VNEEGFAID-DKEYAMKTEQKFASKHSSRLKIERNVMASYSKC---------------DAQCKEHFPELIDFGQSP
|||.  .|.||.| .. ||.|   ...... .. ..|||||.| | . .....|..| ....   ..               ... . |.. ... |  .
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

V-WKWIVMTIVGPSLEELKM-KYKPS-DIPPSTILQCGLQTMKPI
  ....||| .||.||.|.. .  .   .  .|.|....|... .
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEAL
Kinase ZK507.3.AA CK1 173-275 26 1.3e-26 89.87 In-house 215-339 (339) Show / Hide 
Range on Protein: 173-275
Range on HMM: 215-339/339
Sequence Identity: 26% (34 aa)

NGQVRPPRP---KTKMIG-TPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTT-LIDWKGLTRPDA------YAKKQELFTKLKTYEKE----------
..| ||||.   |....| |.||||...|.. |.||||| .|||.|.|.... | .  |.......         .|.| ... | . .           
TWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFFLCCPKKDHD

--PMFKVISIYLDTLVYDSDVKFGFL
  . |  |  |...| |..  .  ..
CPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase ZK507.3.AA Worm6 25-146 29 1.7e-21 74.11 In-house 1-117 (279) Show / Hide 
Range on Protein: 25-146
Range on HMM: 1-117/279
Sequence Identity: 29% (37 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKE---YAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCKEHFPELIDFGQSPV--WKWIVMTIVGPSLE
|||  ..|.||.|.| || .        .||.   .||| |.. .. ... ||.| .|.    ..   |. ||....| |. .    ..||||.||..|.
WKVTKKIGEGGFGAVYKVEDK-------SDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK--CR-HFCKIEDRGKVDNRGFNYIVMTLVGKNLW

ELKMKYKPSDIPPSTILQCGLQTMKPI
.|..      .  .| |....|. ..|
DLRKNRPDRKFSMGTGLKIAIQCLEAI
Kinase ZK507.3.AA TTBKL 25-142 25 5.1e-17 54.08 In-house 1-111 (288) Show / Hide 
Range on Protein: 25-142
Range on HMM: 1-111/288
Sequence Identity: 25% (30 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCKEHFPELIDFGQSPVWKWIVMTIVGPSLEELKMK
|... ..|.||.|.| .|. ..  .     ...||| | .. .. .||.|.| .|.   .. .   . |||.... |. .   ..||| .||.|  |...
WMIVKMIGEGGFGQVYHVWDMKDKK-----DCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNG---SPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKM

YKPSD-IPPSTILQCGLQT
 .  . . ..|.. .| |.
MPNKKRFSDGTWSRIGIQC
Kinase ZK507.3.AA Worm6 173-219 37 1.3e-13 45.46 In-house 168-215 (279) Show / Hide 
Range on Protein: 173-219
Range on HMM: 168-215/279
Sequence Identity: 37% (18 aa)

NGQVRPPR-PKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLV
....|.|| .. .  ||.||...|.|.  |..|.|| |||| | ....
GNELRTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMI
Kinase ZK507.3.AA Dual 173-242 33 2.9e-13 40.82 In-house 171-241 (282) Show / Hide 
Range on Protein: 173-242
Range on HMM: 171-241/282
Sequence Identity: 33% (24 aa)

NGQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTL-IDWKGLTRPDAYAKKQELF
|...|..| | || |. || .||     . || || |.|  |  || |    . |. . ..    |. ..|
NKKHRTARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNF
Kinase ZK507.3.AA Dual 25-125 33 1.3e-12 38.58 In-house 1-105 (282) Show / Hide 
Range on Protein: 25-125
Range on HMM: 1-105/282
Sequence Identity: 33% (36 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCK----EHFPELIDFGQSPVWK--WIVMTIVGPSL
|||.  || || . | .| . .  .    .| |..|||     |   |||.|  ||   .    . |    ..|.|..| |..   |  ..||  .||||
WKVVNLLGSGGFRDVYHVHRFSQVN--PKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSL

EELKMKY
.|   ||
QEIRRKY
Kinase ZK507.3.AA TTBK 174-219 47 1.3e-10 33.72 In-house 156-201 (257) Show / Hide 
Range on Protein: 174-219
Range on HMM: 156-201/257
Sequence Identity: 47% (22 aa)

GQVRPPRPKTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLV
|.|||||. .   || || |  .||  |.||.||  | |.| .  |
GEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFV
Kinase ZK507.3.AA TTBKL 175-268 26 6.2e-10 29.79 In-house 176-277 (288) Show / Hide 
Range on Protein: 175-268
Range on HMM: 176-277/288
Sequence Identity: 26% (28 aa)

QVRPPRP---KTKMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPD-AYAKKQELFTKLKTYEKE------PMFKVISIYLDTL
..|.||.   |.   ||.|||| . |.  |.|| ||  ||..|.| |..  |  |.... ..  ...|... ...  ...       . |  .  .| .|
MMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LP-WTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSL

VYDS
 | .
RYYD
Kinase ZK507.3.AA CK1-Unclassified 182-210 44 1.3e-08 21.54 In-house 173-201 (244) Show / Hide 
Range on Protein: 182-210
Range on HMM: 173-201/244
Sequence Identity: 44% (13 aa)

KTKMIGTPRYCSRASHRCEELGRRDDYES
. ...|| || |  .|.. | .|||| ||
NKNLTGTARYASINAHLGIEQSRRDDLES
Kinase ZK507.3.AA AGC 25-84 20 4.7e-07 12.74 In-house 1-78 (395) Show / Hide 
Range on Protein: 25-84
Range on HMM: 1-78/395
Sequence Identity: 20% (17 aa)

WKVIVELGKGGYGTVNKVIKV-NEEGFAIDD--KEYAMKTEQKFA------SKHSSRLKIE------------RNVMASYS
 ...  .|||..|.|  | |. ...   ..|  | ||||  .|         .   . ..|            ||... ..
FEFLKVIGKGSFGKVYLVRKKDGCH---KKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCN
Kinase ZK507.3.AA CK1 25-126 23 2e-06 18.45 In-house 1-99 (271) Show / Hide 
Range on Protein: 25-126
Range on HMM: 1-99/271
Sequence Identity: 23% (25 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSK--CDAQCKEHFPELIDFGQS--PVWKWIVMTIVGPSLEE
 .|.  .| |  | . ..| .... .   . ..|.| | .  |||.  |..|  ..    .  |     ...| .. .||        .||.  |||||.
YRVGRKIGQGSFGDIYLGINMTNGEE---N-HVAIKLEKN-KSKHP-QLHYEAKIYKILQGHNC-DNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLED

LKMKYK
|.....
LFNFCN
Kinase ZK507.3.AA CK1 182-210 44 7e-06 16.41 In-house 173-201 (271) Show / Hide 
Range on Protein: 182-210
Range on HMM: 173-201/271
Sequence Identity: 44% (13 aa)

KTKMIGTPRYCSRASHRCEELGRRDDYES
. ...|| || |  .| . | .|||| ||
NKNLTGTARYASINTHLGIEQSRRDDMES
Kinase ZK507.3.AA S_TKc 25-295 11 8e-06 -91.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-295
Range on HMM: 1-231/231
Sequence Identity: 11% (38 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCKEHFPELIDFGQSPVWKWIVMTIVGPSLEELKMK
.... ..|||..|.| |.....      .....|.|           ... |.... .         ..   |.|. |.    ..||  .. .| .|.  
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

YKPSD-------IPPSTILQCGLQTMKPIT------------------VSAMDPK------AKQFMYSILDSPESIVSPNGQVRPPRPKTKMIGTPRYCS
 |          .|. ..     |. . .                   ..    |      |.|.                        | ..||| |..
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------------------------TTFCGTPWYMA

RASHRCEELGRRDDYESWFF----------MFIDLVD-TTLIDWKGLTRPDAYAKKQELFTKLKTYEKEPMFKVISIYLDTLVYDSDVKFGFLRDAIT-D
      | |       .. .          ... ..   .. .             |..| |..                    ....|  |.|   . |
-----PEVL-------GYGKCKCDWWSCGCILYEMLCGYPPFP-----------QMQMMFKKIG--------------------SPEAKD-FIRKCLQKD

YA-RSCKLTLKE--------PLV
 . |     . .        | .
PEKRPTA-EALQDEWDIKCHPWF
Kinase ZK507.3.AA CK1-Unclassified 25-126 27 0.000507 7.78 In-house 1-98 (244) Show / Hide 
Range on Protein: 25-126
Range on HMM: 1-98/244
Sequence Identity: 27% (30 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCKE----HFPELIDFGQS--PVWKWIVMTIVGPSL
 .||  .| |  | . |.| ...      ..|.|.| | |  || .. |..|  .|  | . .. | .    ..| .. .||        .||.  ||||
YRVIEKIGQGSFGEIYKCINMQT------NEEVAIKLEKK-NSK-HPQLCYEAKIMQ-YLQNGHNC-DNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSL

EELKMKYK
|.|. ...
EDLFNMCN
Kinase ZK507.3.AA CK1-A 25-121 24 0.001591 8.12 In-house 1-84 (261) Show / Hide 
Range on Protein: 25-121
Range on HMM: 1-84/261
Sequence Identity: 24% (24 aa)

WKVIVELGKGGYGTVNKVIKVNEEGFAIDDKEYAMKTEQKFASKHSSRLKIERNVMASYSKCDAQCKEHFPELIDFGQSPVWKWIVMTIVGPSLEEL
.... ..| | .| .   |...      . .| |.| |.. | .|   |  |  |    ..|       .|..  .|.   .  .|| ..|||||.|
YRLVRKIGSGSFGDIYLGINIT------NGEEVAIKMESNKA-RH-PQLIYEAKVYRILQGCVG-----IPHMRWYGCEKDYNVMVMDLLGPSLEDL
Kinase ZK507.3.AA CK1-A 184-239 35 0.002111 7.68 In-house 164-215 (261) Show / Hide 
Range on Protein: 184-239
Range on HMM: 164-215/261
Sequence Identity: 35% (20 aa)

KMIGTPRYCSRASHRCEELGRRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAKKQ
...|| || |   |   |  |||| ||  ....    ..|  |.|..   | .|||
NLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLP-WQGMK---AMTKKQ
Kinase ZK507.3.AA TTBK 25-37 53 0.173376 1.06 In-house 1-13 (257) Show / Hide 
Range on Protein: 25-37
Range on HMM: 1-13/257
Sequence Identity: 53% (7 aa)

WKVIVELGKGGYG
|||.   | ||.|
WKVVKKIGGGGFG