Gene ZK177.2 (Nematode worm)
ZK177.2
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| ZK177.2.AA | Protein | Genbank | 296 | None | Fasta, JSON |
| ZK177.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 221 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of ZK177.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | ZK177.2.AA | Haspin | 59-279 | 32 | 4.4e-96 | 325.52 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 59-279 Range on HMM: 1-264/264 Sequence Identity: 32% (85 aa) IKKFLGDGASGTAYLVVWEDKEVVMKVTGIHPQSI--------------SVLHDELLITQKIGKLSKS--CHNFLPYHGSIVISDLP-------AKMMRN ..|..|.|..|... |.|..||||||...||.... .....|. |..|.||||.. |.||....|..|....| ||... NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH SECVN---------------HLAIFMGYGGTVLAD--WRTSDYRRCITIMAQLVLAMRIANDKMKFVHGDIYMMNILIA-PTTKRWIEYNIDGKTITIQT .... |....| |||..|.. |.......||.|| |||..|.||.|.|.|.|.|....|.||. .|.|.|..|..|||||.|.. YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS FGIIPQLIDFSKSWCGADPER--HDISRLHTVAKRVGHSLNGSKRDKKKVRQAVKMVGAAKNWK .|.....|||.||.|| |... .|.....|.............||..|..|....|..||||| HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK |
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| Kinase | ZK177.2.AA | MLK | 57-85 | 27 | 1.4e-05 | 15.43 | In-house | 1-29 (291) | Show / Hide |
Range on Protein: 57-85 Range on HMM: 1-29/291 Sequence Identity: 27% (8 aa) VQIKKFLGDGASGTAYLVVWEDKEVVMKV |.....| |..| .. .| |..| |. IQFHEWIGSGSFGKVWKGRWRNKDIVAKI |
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| Kinase | ZK177.2.AA | S_TKc | 57-293 | 11 | 2.8e-05 | -99.55 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 57-293 Range on HMM: 1-231/231 Sequence Identity: 11% (35 aa) VQIKKFLGDGASGTAYLVVWED--KEVVMKVTGIHPQSISVLHDELLITQKIGKLSKSCHNFLPYHGSIVISDLPAKMMRNSECVNHLAIFMGYGGT--- .| . .| || |. |.... . ..| .|. . |. | .| . | ...... .|| ..| | .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD--------------DHLYMVMEYCDGDLG VLADWRTSDYR---------RCITIMAQLVLAMRIANDKMKFVHGDIYMMNILIAPTTKR-------------------------WIEYNIDGKTITIQT | | . | .. .|.|...|. .. ...| |. |||. . . ... . . DLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQLTTFCGTPWYMAPEVL--GYGKCKCDWWS FGIIPQLIDFSKS-WCGADPERHDISRLHTVAKRVGHSLNGSKRDKKKVRQAVKMVGAAKNWKNLCLYR--------QLFK-------QVIV .|.| . .. .... |..| ||. . || . .... . CGCILYEMLCGYPPFP----------QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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