Gene ZC581.9 (Nematode worm)

ZC581.9

Species: Nematode worm
Alias: aSWK242, ZC581.9, CE27789
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:1.22, WormBase Physical Map location: I: 6678205-6673246

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
ZC581.9.AA Protein Genbank 827 None Fasta, JSON
ZC581.9.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 203 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of ZC581.9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ZC581.9.AA SCY1 78-344 29 1e-102 347.53 In-house 1-337 (337) Show / Hide 
Range on Protein: 78-344
Range on HMM: 1-337/337
Sequence Identity: 29% (100 aa)

WRIFNSKSVFGNKDASVLVFDKKSNVKAPPKLGKSKTYSMFDLIKYETQQLMGLIHPRILHMEHSLEETKDYISFATEQIFGNLENVVTDES--------
|.|.|....  ..  ||.|||||.  |. .. ....     ...| . ..|. | ||.|| ..|.|||.||....|||.|| .||||.....        
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEE---ICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQ

-----------------------LDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGG---------FSFAVNAKEPN----CYPCY
                       ||.||...|..||.|..|.|||...|.|.|..|..|.|.....|||||         . | .... .|    ..||.
KTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQ

PW-------------TKKLPPCLQPDLDFLAPENLAPGQ-----------TTVTSAADVFSLGVLICWIYAGGKRLIDAKSN-LETYHIVVGQLDAALQC
.|             ..|.||..||..|.||||.....|           ...| |.|.||||.||.|.|.|.|..|...|| ..|.|....|..|...|
EWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHC

ISNELGPNLKDS----MAKVLSLDVEVRPTVQLLSLIKHF
..... ..|...    . ..|. |...||..|...... |
WWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
Kinase ZC581.9.AA S_TKc 81-344 15 7.4e-09 -47.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 81-344
Range on HMM: 1-231/231
Sequence Identity: 15% (46 aa)

FNSKSVFG-----------NKDASVLVFDKKSNVKAPPKLGKSKTYSMFDLIKYETQQLMGLIHPRILHMEHSLEETKDYISFATEQIFG---NLENVVT
.    . |           .|.   .|  |. .                . |. | | |.   || | ..  . ..  |.. . .| . |   .|  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIK

DES-------LDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNCYPCYPWTKKLPPCLQPDLDFLAPENLAPGQ
.         ..  ...  . ||.... |.|.  . .|  | |. | ..   . ||. | .|                    .    ....||| |    
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGT-PWYMAPEVL----

TTVTS-AADVFSLGVLICWIYAGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSL-------IKHF
   .  ..|. |.|...   .. |. . .     .......               | .|| . | |  | | |||.  .            |
-GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ZC581.9.AA RGC 182-202 52 2e-06 18.64 In-house 94-114 (300) Show / Hide 
Range on Protein: 182-202
Range on HMM: 94-114/300
Sequence Identity: 52% (11 aa)

IIDGMSYLHNSAKMLHGNLTP
|. || |||.|    ||||..
IVKGMQYLHHSPIRYHGNLKS
Kinase ZC581.9.AA RGC 182-202 52 2e-06 18.64 In-house 94-114 (300) Show / Hide 
Range on Protein: 182-202
Range on HMM: 94-114/300
Sequence Identity: 52% (11 aa)

IIDGMSYLHNSAKMLHGNLTP
|. || |||.|    ||||..
IVKGMQYLHHSPIRYHGNLKS
Kinase ZC581.9.AA TKL-Unique 179-221 24 4e-06 17.64 In-house 116-164 (290) Show / Hide 
Range on Protein: 179-221
Range on HMM: 116-164/290
Sequence Identity: 24% (12 aa)

VLQIIDGMSYLHNSAK-MLHGNLTPDAIYVTAT-----KTWKIGGFSFA
...| .|| |||.. . ..|..|.. ...|.          || .|...
AIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLS
Kinase ZC581.9.AA NRBP 181-345 23 1.1e-05 15.64 In-house 111-261 (261) Show / Hide 
Range on Protein: 181-345
Range on HMM: 111-261/261
Sequence Identity: 23% (39 aa)

QIIDGMSYLHNSA-KMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNCYPCYPWTKKLPPCLQPDLDFLAPENLAPGQTTVTSAADVFSLGVLICWIY
||.  .|||| .   ..||||| |.|..      |||  . . .| . .   |    ..        . |.|||      | .|.|.|..| |  .| . 
QILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIG--CVWPDAIHHHVRTCREEMRN--------MHFFAPEYGILEVTDLTTAVDIYSFG--MCALE

AGGKRLIDAKSNLETYHIVVGQLDAALQCISNELGPNLKDSMAKVLSLDVEVRPTVQLLSLIKHFD
        . .| |.  .    .. | . .....    .| . | |  | . ||. . |   .   
MAVLEIQSGCQNGESEYVTEEAIQRAIHSLEDPM---QRDFIRKCLQKDPARRPSARELLFHQILF
Kinase ZC581.9.AA PEK-Unclassified 181-218 35 4.5e-05 12.35 In-house 621-659 (835) Show / Hide 
Range on Protein: 181-218
Range on HMM: 621-659/835
Sequence Identity: 35% (14 aa)

QIIDGMSYLHNSAKMLHGNLTPDAIYVTAT-KTWKIGGF
||| .. . |   || |  ..|. |.|.      ||| |
QIIKALYHIHHQCKMVHRDIKPHNIFVCQNPMQIKIGDF
Kinase ZC581.9.AA Ciliate-E2 181-275 18 4.6e-05 13.32 In-house 168-286 (365) Show / Hide 
Range on Protein: 181-275
Range on HMM: 168-286/365
Sequence Identity: 18% (24 aa)

QIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEPNC-----YPCYPWTKKL------PPCLQPDL--------------DFLAPENL
.||... |||.  . .| .. |. | .      ||  | .. .....|.       |. ..         | ...  .               ..|||.|
CIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD--QIIQQNMFNTICGTPGYMAPEIL

A-PG------QTTVTSAADVFSLGVLI
   .      |.  . ..|..||||..
NGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase ZC581.9.AA PKR 181-221 36 0.000213 11.51 In-house 131-170 (272) Show / Hide 
Range on Protein: 181-221
Range on HMM: 131-170/272
Sequence Identity: 36% (15 aa)

QIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFA
||. |. |.| | |..|  | |  |..  ..  ||| |  .
QIVKGVDYIH-SKKLIHRDLKPSNIFLVDERHIKIGDFGLV
TyrKc ZC581.9.AA TyrKc 71-341 17 0.000267 -153.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 71-341
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

YRLT------------HGHWRIFNSKSVFGNKDASVLVFDKKSNVKAPPKLGKSKTYSMFDLIKYETQQLMGL--IHPRILHMEHSLEETK------DYI
 .|             .|.|.              . |  |. .  |               .  | . .. |   || |. .     . .      . .
ITLGKKLGEGAFGEVYKGTWK--------------IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

SFATEQI-FGNLENVVTDES--LDRLEIKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFAVNAKEP-------NCYPC--YPWTKK
   .|    |.| .   .    |   .     .|| .||.|||   .  |  |    . |.. .| ||. |  . . ..          |       .| 
MIVMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKT

-LPPCLQPDLDFLAPENLAPGQTTV-TSAADVFSLGVLICWIYAGGKRLIDA-----KSNLETYHIVVGQLDAALQCISN-------ELGPNLKDSMAKV
 ||      .  .||| .   .. . |.. ||.| ||..  |.  |.          .|| | .. |  .    . .  |       .  . . . | . 
MLP------IRWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV--KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQC

LSLDVEVRPT-VQLLSLI
   | | |||  .. ...
WHEDPEDRPTFSEIHECF
Kinase ZC581.9.AA Ciliate-E2-Unclassified 181-275 19 0.000675 9.43 In-house 151-260 (352) Show / Hide 
Range on Protein: 181-275
Range on HMM: 151-260/352
Sequence Identity: 19% (22 aa)

QIIDGMSYLHNSAKMLHGNLTPDAIYVTATK---TWKIGGFSFAVNAKEPNCYPCY---PWTKKLPPCLQPDL----DFL----APENLAPGQTTVT--S
||..| .||| . . .| ...|. | ..  .     || .|... . ...| .  .   . .. ...... .      ..    ||| |   .   .   
QILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAY

AADVFSLGVLI
..|..||||..
KCDIWSLGVIL
Kinase ZC581.9.AA nmo 175-221 36 0.000847 6.88 In-house 104-149 (292) Show / Hide 
Range on Protein: 175-221
Range on HMM: 104-149/292
Sequence Identity: 36% (17 aa)

IKLGVLQIIDGMSYLHNSAKMLHGNLTPDAIYVTATKTWKIGGFSFA
.|  . ||. |. ||| ||..||  . |  . | .    ||  |  |
VKVFLYQILRGLKYLH-SANILHRDIKPGNLLVNSNCVLKICDFGLA