Gene ZC581.7 (Nematode worm)

ZC581.7

Species: Nematode worm
Alias: aSWK348, ZC581.7, CE28168
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:1.22, WormBase Physical Map location: I: 6670350-6668550

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
ZC581.7.AA Protein Genbank 395 None Fasta, JSON
ZC581.7.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 254 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of ZC581.7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 ZC581.7.AA SH2 14-96 27 1.8e-07 32.06 SMART 1-87 (87) Show / Hide 
Range on Protein: 14-96
Range on HMM: 1-87/87
Sequence Identity: 27% (25 aa)

LPYYHGALMNQDADQLLVN----DGDYMIVVKMNQELNKMQLYLAVRLKKGIRRFEIKRNP-TSAKIGG---KSAPNIGKLVDSMQKETME
 |.||| .  ..|.||| |    |||...    .   |. .. | || |.... . |.||.  .  |..   .. |..  ||.  |.    
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase ZC581.7.AA Fer 120-372 41 1.4e-133 450.09 In-house 1-283 (283) Show / Hide 
Range on Protein: 120-372
Range on HMM: 1-283/283
Sequence Identity: 41% (117 aa)

VDFKKKLGSGAYGTVYLGR----------LTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQL-YDHPNIVKFYGYIVDDIPYLLVLELCNGGSVEDKL
|...||||.||.|.||.||          ...|.....|||...|. ..| ..|.|.|||.|.  |||||.|||||..||. |...|.|.|||||....|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

VEKGAK-LSTKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIHKEIVK----IADFGMCRATSIYKVDLNKP-----TNTRWLAPEVWDNGETRDNTD
 ....| .|....| ..|.||||.||||.|.||||||||||||.||. ||    |.||||.|..| |..|  ..      ..||||||.|..|... .||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

IFAFAITMWEFFEVPYDSPYS--------EWKGYMVKQKTRAGYRLPTPKGMPWDIEEIMK-LCWHVDPNQRPTASELREKIE
...| ...||.|. ......         ..|....|.....||..| |..||..| .||.  ||..||..|||..|...|..
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase ZC581.7.AA Pkinase_Tyr 120-371 35 7.6e-101 342.17 Pfam 1-270 (270) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-270/270
Sequence Identity: 35% (96 aa)

VDFKKKLGSGAYGTVYLGRLT----KNNTKIAVKKLDTEGNDEES--LAEMMKEARVMQLY-DHPNIVKFYGYIV-DDIP--YLLVLELCNGGSVEDKLV
. | ||||.||.|.||.|...    ..... |||.|  || ..|   ....|.||..|  . .|||||..|| .. .. |  ...|.|.. .|.  | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EK---GAKLSTKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIH-KEIVKIADFGMCRAT---SIY-KVDLNKPTNTRWLAPEVWDNGETRDNTDIFA
..   . .|..|. . . .  |.| |||. |.|||||.||||||.. . .|||.|||..|.    . | ..  . .   .|.|||.. .|.    .|. .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FAITMWEFFEVPYDSP-YSEWKGYMVKQKT-RAGYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKI
| ..||| |     .| | ... . |...  . |||.| |.. | .| ..||.||| ||..||| ||..|..
FGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase ZC581.7.AA TyrKc 120-371 33 6.7e-87 295.92 SMART 1-280 (280) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-280/280
Sequence Identity: 33% (97 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQLY--DHPNIVKFYGYIVDD-------IPYLLVLELCNGGSVEDKLVE
. ..||||.||.|.||.|...   .. |||.|  .      ....|.|||.|  .  .|||||..||.....        |...|.|.. .|.  | | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KGAKLSTKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIHKE-IVKIADFGMCRAT----------SIYKV----DLNKPTNTRWLAPEVWDNGETRD
.. ||..|. . . . .||| ||||.|.|||||.||||||.... .|||.|||..|.           . |..    . . .   ||.|||... |.   
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

NTDIFAFAITMWEFFEVPYDSPYSE-----WKGYMVKQKTRAGYRLPTPKG--------MPWDIEEIMKLCWHVDPNQRPTASELREKI
 .|...| ..||| |    ..||..      . . | .. ..|||.| |.         .| .. .||| ||| ||..||| ||..|..
KSDVWSFGVCMWEIFTYG-QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase ZC581.7.AA TK 120-371 19 7e-82 274.15 In-house 1-486 (486) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-486/486
Sequence Identity: 19% (95 aa)

VDFKKKLGSGAYG---TVYLGRLTKNN-------------------------TKIAVKKLD--TEGNDEESLAEMMK----------EARVMQLYD----
. . ||||.|..|   .||.|..   |                         |. ||| |   .. ..|| ..|.|.          ||..|.. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNIVKFYGYIVDD------------IPYLLVLELCNGGS----VEDKLVEKGAK--------------------------------------------
 |||||..||.....             |...|.|....|.      | | ..  |                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSTKTRIMYTYHAACGIEYLHKKKC------IHRDIAARNCLIHKE------------IVKIADFGMCR
                               |...... . . .||| ||||.|.|      .|||.||||||....            ..||||||..|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

ATS-----------IYKVDL------------------------NKPTNTRWLAPEVWDNGETRDN---------TDIFAFAITMWEFFEVPYDSPYSEW
..|            | ..                         .     ||.|||... .. .           .|...| ..||| |      .| ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

KG---------YMVKQKTRAG--------------YRLPTPKGMP--------------WDIEEIMKLCWHVDPNQRPTASELREKI
             | .. |.|              .|.| |...|               .....|. ||| ||..||| |.|.|..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase ZC581.7.AA UTK 120-371 26 1.6e-64 219.62 In-house 1-296 (296) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-296/296
Sequence Identity: 26% (78 aa)

VDFKKKLGSGAYGTVYLGRLTKNN-----TKIAVKKLDTEGNDEESLA---EMMKEAR---VMQLYD-HPNIVKFYGYIVDDIPYLLVLELCNGGSVED-
| . ..||.||.|.|...|.|. .      . |||......... . .   . |.|||   .|.  . |||.....|. ... | ..|.|.. .|.  . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

------KLVEKGAKLSTKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIHKE--------IVKIADFG---MCRATS------------IYKVDLNKP
      .. . .. |.  .|. . .. |.| .||| ....|||.||||||.|.         ..||||||   |.|. .             |. . ...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

TNTRWLAPEVWDNG-ETRDNTDIFAFAITMWEFFEVPYDSPYSEWKGYMVKQKTRAG--YRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKI
   || |||. ...      .|...| ...|| .      || ..    | .  ..|  ||.| |...|... ..|. ||| ||  ||.. .|....
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW-GRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase ZC581.7.AA TKL 126-371 21 1.1e-56 194.7 In-house 1-364 (364) Show / Hide 
Range on Protein: 126-371
Range on HMM: 1-364/364
Sequence Identity: 21% (78 aa)

LGSGAYGTVYLGRLTKNN--------TKIAVKKLDTEGNDEESL-----------------------AEMMKEARVMQLYD--HPNIVKFYGYIVDDIP-
.|||..|.|| |..  ..        . .||||. .. .||...                       ..  .|  .|..    |||||.|.||  .  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YLLVLELCNGGSVEDKLVEKGAKLSTKTRIMYTYHAACGIEYLHK--------KKCIHRDIAARNCLIHKEI---------------V
            . .| |.| ||| .. |           |.   . .|.|..|||         .. ||||.  .|.|...                 .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIADFGMCRATS-------------------IYKVDLNKPT-NTRWLAPEVWDNGETRDNT----------------DIFAFAITMWEFFE--VPYD-SP
||.||| .|  |                    ..  ....  ..||.|||| .. .  ..                 |...|.| .|| .   .||.  |
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

YSEWKGY-----MVKQKTRAGYRLPTP------------KGMPWDIEEIMKLCWHVDPNQRPTASELREKI
|.....      | ..    |.|.| |            . .| .. ..|. ||. ||..||...|. ...
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ZC581.7.AA TK-Unique 120-371 24 4.9e-49 167.23 In-house 1-294 (294) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-294/294
Sequence Identity: 24% (73 aa)

VDFKKKLGSGAYGTVYLGRLTKNN-----TKIAVKKLDTEGNDEESLAEMMKEARVMQLYD-HPNIVKFYGYIVDD-IPYLLVLELCNGGSVEDKLVEKG
. .....|.||.|.|. | .....     .|... |.  ....... ....||...|.  . |||||...|. ... .| ....| | .|. .. | ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AK-------------------------LSTKTRIMYTYHAACGIEYLHK--KKCIHRDIAARNCLI-HKEIVKIADFGMCR----ATSIYKVDLNKPTNT
 .                         .| |. . . .  ||| |||..  ||..|||..|||.|. .. ..||.|||| |     . . . .  ...  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWLAPEVWD--NGET-RDNTDIFAFAITMWEFF---EVPYDSPYSEWKGYMVKQKTRAGYRLPTPKGM-PWDIEEIMKLCWHVDPNQRPTASELREKI
||.|||.     |   .  .|. .|...||| |   . || . ...     . .. |.|||.| |..  . .. ..|| ||. .| .||. .... ..
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKD----IMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase ZC581.7.AA S_TKc 120-375 23 1.3e-48 168.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 120-375
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQLYDHPNIVKFYGYIVDDIPYLLVLELCNG--GSVEDKLVEKGAK---
 .. .|.|.||.|.||..| .| . . |.|...           ...| ....  .||||||.|....|   . .|.|.|.|  |.. | ....| .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSTKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIHKEIVKIADFGMCRATSIYKVDLNKPTNTR-----WLAPEVWDNGETRD-NTDIFAFAITM
  ..  .   |.|  .|..||.|... ||||.   | |. .  .||.|||..|             .|      ..||||           |. .. ...
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

WEFFE--VPYDSPYSEWKGYMVKQKTRAGYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELRE-----KIEETM
.|..    |..        .|. .| .           . .  .... |...||..|||| |. .     |. . .
YEMLCGYPPFP------QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ZC581.7.AA Frk 120-375 31 1.2e-44 152.48 In-house 1-260 (260) Show / Hide 
Range on Protein: 120-375
Range on HMM: 1-260/260
Sequence Identity: 31% (84 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQLYDHPNIVKFYGYIVDDIPYLLVLELCNGGSVEDKLV---EKGAKLS
. . ..|||| .| |. |.   |.| .|||.| .   | .   ....||..|.   || ... |     . | ... ||   ||. . |    .|| .. 
IQLIRRLGSGQFGEVWEGLW-NNTTPVAVKTLKPGTMDPN---DFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQ

TKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLI-HKEIVKIADFGMCR-----ATSIYKVDLNKPTNTRWLAPEVWDNGETRDNTDIFAFAITMWEFF
 .. .  .   | |. || ..  ||||.|||| |.  . |.||||||. |        ||    .     .| |||     .     |...| | . |  
MQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEI-

EVPYDS-PYSEWKGYMVKQKTRAGYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKIEETM
 . |   ||.   .  | |   .|||.| | . |  . |||  |||.||..|||   |. |.|. .
-ITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase ZC581.7.AA Pkinase 120-371 21 1.3e-43 155.32 Pfam 1-293 (293) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-293/293
Sequence Identity: 21% (63 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMK--EARVMQLYDHPNIVKFYGYIVDDIPYLLVLELCNGG----SVEDKLV-EKG
  ...|.|||..|.||...  ... . |||... ...... . .  .  |...|.  .|||||..|..  |.  . .|.|.|.||    .  | .  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

AKL--STKTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLIH-KEIV----KIADFGMCRATSIYKVDLNKPTNT---RWLAPEV--WDNGETRDNTDIF
 ..  | .. ..| |  ..|.||.|....||||.   |.||. .  .    ||.||| ..  . |  .    | .   ...||||   ... ..   |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP-KVDMW

AFAITMWEFFE--VPYDSP----YSEWKGYMVKQKTRAGYRLPTPKG-------------------MPWDIEEIMKLCWHVDPNQRPTASELREK--I
.. ....|..    |...         . .|.... .. .. . |.                    .. .  ...| |...||..|||| .. .   .
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ZC581.7.AA Abl 120-371 32 1.6e-43 142.73 In-house 1-252 (252) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-252/252
Sequence Identity: 32% (83 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQLYDHPNIVKFYGYIVDDIPYLLVLELCNGGSVEDKLVEKGAKLSTKT
.  |.||| | || || |   . .  .||| |     |   . | .||| .|.   |||.|.  |    . |. .. |    | . | | | . .. .  
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLK---EDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAV

RIMY-TYHAACGIEYLHKKKCIHRDIAARNCLI-HKEIVKIADFGMCR--ATSIYKVDLNKPTNTRWLAPEVWDNGETRDNTDIFAFAITMWEFFEVPYD
 ..|     | |..|| |.. ||||.||||||.  ..|||.||||. |     .|          .| |||     .     |..|| . .||       
VLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGM-

SPYSEWKGYMVKQKTRAGYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKI
|||       | .|   |||.  |.| | .. |.|. ||. ..  ||.  |. ...
SPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase ZC581.7.AA TKL-Unique 122-371 28 4.7e-43 149.34 In-house 1-290 (290) Show / Hide 
Range on Protein: 122-371
Range on HMM: 1-290/290
Sequence Identity: 28% (83 aa)

FKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDT-EGNDEESLAEMMKEARVMQLYD-HPNIVKFYGYIVD---DIP-YLLVLELCNGGSVEDKLV------
| .|.|.|.||.|| |    . ...|.|..   |.   |.. |  .| ..|   . |||||...|| .|   ..| . .|.| |.|||  | |       
FWNKIGEGGYGQVYKGKW--RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---EKGAKLSTKTRIMYTYHAACGIEYLHKKK--CIHRDIAARNCLIHKE------IVKIADFGMCRATS-IYKVDLNKP---------TNTRWLAPEVW
   ..  ||. . |.     .| | .||| ..   ||||.  .| |.  .       .||.||| ..  | | |  .| .         ...||.|||| 
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

DNG-ETRDNT-DIFAFAITMWEFFEVPY----DSPYSEWKGYMVKQKTRA---GYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKI
 .  .....  |...|.| .|| ..         ||..   . .... .    .||.| |  .| .. .... ||| || |||. .| ....
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase ZC581.7.AA MLK 120-371 23 1.3e-39 135.11 In-house 1-291 (291) Show / Hide 
Range on Protein: 120-371
Range on HMM: 1-291/291
Sequence Identity: 23% (71 aa)

VDFKKKLGSGAYGTVYLGRLTKNN---TKIAVKKLDTEGNDEESLAE-----MMKEARVMQLYDHPN----IVKFYGYIVDDIP-YLLVLELCNGGSVED
 .|....|||..| |..||  ...     .|||. ...   . | ..     . .|.|     .|||    |..||| . .. . ...|.| | |||  .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

KLVE-KG------------AKLSTKTRIMYTYHAACGIEYLHKKK---CIHRDIAARNCLIH-------KEIVKIADFGMCRATSIYKV---DLNKPTNT
 | . ..            .  .    .   .  | |..|||...    ||||.  .| ||.       ....||.|||   ......      ... . 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGT--SRDWHQMCTNMMSNAGTY

RWLAPEVW---DNGETRDNTDIFAFAITMWEFF--EVPYD-SPYSEWKGYMVKQKTRAGYRLPTPKGMPWDIEEIMKLCWHVDPNQRPTASELREKI
.| ||||     ..      |.. ... .|| .  ||||.   ..   ...|   .  | |.| |.. |  ... || ||. ||..||. ..  .. 
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWV---AYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase ZC581.7.AA Src 120-286 32 3.6e-28 92.75 In-house 1-170 (255) Show / Hide 
Range on Protein: 120-286
Range on HMM: 1-170/255
Sequence Identity: 32% (57 aa)

VDFKKKLGSGAYGTVYLGRLTKNNTKIAVKKLDTEGNDEESLAEMMKEARVMQLYDHPNIVKFYGYIVDDIPYLLVLELCNGGSVEDKLV--EKGAKLST
. ...|||.| .| |. |   ..||| ||| |  .|.   | .   .|| .|   .|...|. |    .. |.. | |. . ||  | |   ..| .|. 
IKLCRKLGQGQFGEVWMGYW-NGNTKVAVKTL-KPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHL

KTRIMYTYHAACGIEYLHKKKCIHRDIAARNCLI-HKEIVKIADFGMCRATS----IY--KVDLNKPTNTRWLAPE
.. |  . . | | .|| ... |||| |||| |. .. ..|.||||  | .     .|  . . . |   .| |||
PQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFP--IKWTAPE
Kinase ZC581.7.AA Src 317-371 41 1.4e-13 42.42 In-house 200-255 (255) Show / Hide 
Range on Protein: 317-371
Range on HMM: 200-255/255
Sequence Identity: 41% (23 aa)

PYSEWKGYMVKQKTRAGYRLPTPKGMPWDIEE-IMKLCWHVDPNQRPTASELREKI
||  ..   | |.  .|||.| |.. |  . | ||. ||| || ||||   |... 
PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL