Gene Y48G1C.2 (Nematode worm)
Y48G1C.2
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| Y48G1C.2.AA | Protein | Sugen | 539 | None | Fasta, JSON |
| Y48G1C.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 252 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of Y48G1C.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| SH3_2 | Y48G1C.2.AA | SH3_2 | 70-108 | 15 | 9e-05 | 19.6 | Pfam | 24-68 (68) | Show / Hide |
Range on Protein: 70-108 Range on HMM: 24-68/68 Sequence Identity: 15% (7 aa) FRKDDHVRIL--GNTTDPAWYRA-RN-ANQEE--GLVHADCVVRI |.|.| .... |.. .. |... .. .. .. |... ..| . FKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC |
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| SH2 | Y48G1C.2.AA | SH2 | 151-226 | 45 | 2e-36 | 108.75 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 151-226 Range on HMM: 1-81/81 Sequence Identity: 45% (37 aa) WFHSMISRENTEKLLRG--KPDGTFLVRESTNFPGDFTLCMSFHG---KVEHYRIEQTSGGQLTCDKEEYFSNLTQLVSHY |.| |||. |.||. .|||||||||| . |||.||. . | .|.|||| .| .|.. . ...|..| .||.|| WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY |
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| SH2 | Y48G1C.2.AA | SH2 | 149-232 | 44 | 1.2e-35 | 125.7 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 149-232 Range on HMM: 1-87/87 Sequence Identity: 44% (39 aa) QPWFHSMISRENTEKLLRG--KPDGTFLVRESTNFPGDFTLCMSFHGKVEHYRIEQTSGGQLTCDK--EEYFSNLTQLVSHYKRDADG |||.| .|||| |.||.. .|||.||||.| ..|||..|.. ..||| ||||... |. .| ...|..| .|| ||.. ..| QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
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| Kinase | Y48G1C.2.AA | Csk | 283-532 | 66 | 8.20000000001e-201 | 673.41 | In-house | 1-251 (251) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-251/251 Sequence Identity: 66% (166 aa) IDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVN-VYMITEYMANGNLIDLLRSRGRHALERRQLM ...|..|||||||||..|.|.|||||.|..|..||||....|.||..|..|.|||||.|.||.|...| .|...|||..|||.|.|||||||...||||. LHLGECIGHGEFGDVMQGEYQNRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQLL MFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYPR .||||.|.||||||.|..|||||||||.|...|.|||||||||||...||..||.||||||||||||||||..|.|||||||||||||||.||||||||| KFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRVPYPR IPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL ||..|||...||||||||||||||...|||...|.|....||.|.||...| IPLKDVVKHVEKGYRMEAPEGCPPHVYKVMKQCWHLNPAKRPTFRQVREQL |
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| Kinase | Y48G1C.2.AA | Pkinase_Tyr | 283-532 | 41 | 2.7e-123 | 418.17 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-270/270 Sequence Identity: 41% (111 aa) IDVGDTIGHGEFGDVRLGTYK------NRKVALKVSKRHGNGM---LDSLLDEAKFMVGL-SHPNLVTLVGVVL-DDVN--VYMITEYMANGNLIDLLRS | | ..|.|.||.|..||.| . .|| |. | . ..... ||| | | .|||.| |.||.. .. .|...|||..|.| | ||. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK R--GRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKA--NSQS-HDSASGKFPIKWTAPEALRHSQFTTKSDVWSF . ....| .| ....|..|| |||||...||||||||.|.....|.|..|||||. .. . . .||.||||.|||..... |||||||||| HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF GILLWEIFSFGRVP-YPRIPIQDVVRYI-EKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL |.|.||||..|. | || .. ..|..|| |.||||..||.||.|| ..| . |. ..|||.| .....| GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | Y48G1C.2.AA | TyrKc | 283-532 | 35 | 7.29999999999e-121 | 408.74 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-280/280 Sequence Identity: 35% (102 aa) IDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGL--SHPNLVTLVGVVLDD-------VNVYMITEYMANGNLIDLLRSRGRH | |...|.|.|| |..||.| ..|| |. | . . ...||. | | .|||.| |.||.... .....|||..|.| | ||..... ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK ALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQ-------SHDSA----SGK--FPIKWTAPEALRHSQFTTKSD | ..| |. .|..|| ||.||...||||||||.|.......|.|||||... . . .. .|| .||.|.|||..... |||||| -LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD VWSFGILLWEIFSFGRVPYPR-----IPIQDVVRYIEKGYRMEAPEG--------CPPEIFKVMNETWALSAQDRPSFGQVLQRL |||||...||||..| ||| .. |.|..|...||||. |. ||.|....| . |. . |||.| .. ... VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | Y48G1C.2.AA | TK | 283-532 | 21 | 3.3e-110 | 370.77 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 283-532
Range on HMM: 1-486/486
Sequence Identity: 21% (107 aa)
IDVGDTIGHGEFG---DVRLGTYKNR---------------------------KVALKVSKRHGNGMLDSLLD--------------EAKFMVGLS----
| .|...|.|.|| .|..|....| .|| |. | . . . .| || | ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HPNLVTLVGVVLDDVN------------VYMITEYMANGN----LIDLLRSRG----------------------------------------------
|||.| |.||...... .....|||..|. | | ||..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
----------------------------RHALERRQLMMFAMDICQGMCYLESK------QIVHRDLAARNVLLDDDLV-----------AKVSDFG---
.| | .||. ....|..|| ||.|| ..|||||||||.|.....| .|..|||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----LAKKAN-------SQSHDSA-------------------SGKFPIKWTAPEALRHSQ---------FTTKSDVWSFGILLWEIFSFGRVPYPR-I
||.. . ..|.. . .||.||.|.|||.|.. . |||||||||||.|.||||..|..||. .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
PI---------QDVVRYIEKG--------------YRMEAPEGCP--------------PEIFKVMNETWALSAQDRPSFGQVLQRL
. |.|..|...| .||..|..|| .|.. .| . |.. ..|||.| |....|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | Y48G1C.2.AA | TK-Unique | 283-532 | 37 | 1.8e-100 | 340.13 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-294/294 Sequence Identity: 37% (109 aa) IDVGDTIGHGEFGDVRLGTYKN--------RKVALKVSKRHGNGM-LDSLLDEAKFMVGLS-HPNLVTLVGVVLDDV-NVYMITEYMANGNLIDLLRSRG . |||.|| |.|| | |.... ..||.| |.. .. . .|.|...| | |||.|...|. .. ....| ||...||| ..||... LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR RH------------------------ALERRQLMMFAMDICQGMCYLES--KQIVHRDLAARNVLLDDDLVAKVSDFGLAK---KANSQSHDSASGKFPI . .. ..| || .|..|| ||.| |.||||||.|||||| .|.|.|..|||.|. . . .| .|. || PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI KWTAPEALR--HSQF-TTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKGYRMEAPEGC-PPEIFKVMNETWALSAQDRPSFGQVLQRL .| |||.|. | .. ||||||||||.|.||||..| |||..| |... |..||||. ||.| ..|....| ..| .....|||| |...|| RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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| Kinase | Y48G1C.2.AA | Src | 283-532 | 42 | 1.2e-99 | 337.35 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-255/255 Sequence Identity: 42% (108 aa) IDVGDTIGHGEFGDVRLGTYKN-RKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLR-SRGRHALERRQL | . .| | ||.| |.... ||| |. |. |. . .| ||. | |.|..|| | |. .. .| .||||..|.| | |. .. ..|. .|| IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKP-GTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQL MMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKAN--SQSH-DSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRV .| . .||.||||....|||||||||| ....|.|| |||||. . |||||||||||... .||.|||||||||||.||...||| IDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRV PYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFK-VMNETWALSAQDRPSFGQVLQRL ||| ..|.. .|.|||| |..||.|... .| . | ....|| | . | PYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | Y48G1C.2.AA | UTK | 283-532 | 33 | 7.4e-98 | 331.4 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-296/296 Sequence Identity: 33% (100 aa) IDVGDTIGHGEFGDVRLGTYKN-------RKVALKVSKRHGNGMLDSL-----LDEAK---FMVGLS-HPNLVTLVGVVLDDVNVYMITEYMANGNLIDL . |...|.|.||.|....... .||.|| ..|... .. . ||. .| .. |||.. ||||.... ...||||.||.|... VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LRSRGR------HALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDD-------LVAKVSDFG---LAKKANS-----------QSHDSASGK ||. .. |.| .|.. .|.|| || ||.|...|||||||||.|.... .|.|..||| ... .|. . . .. LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR FPIKWTAPEALRHS-QFTTKSDVWSFGILLWEIFSFGRVPYPRIPIQDVVRYIEKG--YRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL ||.|.||||| | .|||||||||||...|||...||.||| . ..|. ...| |||..|..|| .....|.. |. . |.||.| ...|.. WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | Y48G1C.2.AA | SFK-Src | 283-536 | 41 | 2.9e-93 | 276.73 | In-house | 1-259 (259) | Show / Hide |
Range on Protein: 283-536 Range on HMM: 1-259/259 Sequence Identity: 41% (109 aa) IDVGDTIGHGEFGDVRLGTYKNR-KVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRS-RGRHALERRQL | | | |||| |. | || | | | . | || | | ||||. | | | .| ||| |..| | | |.. .|| .| || IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLK-PGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGR-SLRMPQL MMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSH---DSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRV | .. || ||| . ||||||||||| | | || |||.. .. ||||||||||| ..| .||||||||||. || .||. VDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRI PYPRIPIQDVVRYIEK--GYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTTIR ||| . |.. ... ||||..| .||.| .|.| . | . ||| |. . .. PYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF |
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| Kinase | Y48G1C.2.AA | Abl | 283-532 | 43 | 4e-89 | 297.44 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-252/252 Sequence Identity: 43% (110 aa) IDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGM-LDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQLM | . . .| | .|.| | .| . . | . . | .. | || | . ||||| |.|| . |.|||.|..|||.| ||. .|. |. |. IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAVVLL MFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASG-KFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYP | | || |||... .|||||||| |. .. . || |||||. . . | ||||||||||.| . .| .||||| ||.||||| .| ||| YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYP RIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL | ...| .||||||| ||||||.....| . | |. ||||| .. ... GIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM |
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| Kinase | Y48G1C.2.AA | SFK-Abl | 283-532 | 43 | 7.5e-86 | 280.16 | In-house | 1-251 (251) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-251/251 Sequence Identity: 43% (109 aa) IDVGDTIGHGEFGDVRLGTYKNRKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRS-RGRHALERRQLM | |. | |..| | | . |..|| | | | . || | . ||||| |.|| . | ..|.| .||| | |.| ..| . .| IILGHRLGEGQYGEVYKGIWNNHRVAIKTIKDESMETKD-FMKEAHIMKRMQHPNLVRLIGVCTREGPMYIVQEFMNYGNLLDYLQSPQSRIQIDHVSMM MFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASG-KFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVPYP |. | || || . .|||||||| | | | || |||.| | . . | |.||||||||.| || ||||||||| |||| .| |||| HCAQQIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARFVDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSFGITLWEIATYGDVPYP RIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL | ||. . |||| |..|| ||. .| |.. |||| . . | GIHHRDVINQLMMGYRMQRPQDCPMEIYNIMTQCWDVNPDERPSFHDLQHQL |
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| Kinase | Y48G1C.2.AA | Tec | 283-534 | 38 | 1.1e-84 | 287.62 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 283-534 Range on HMM: 1-254/254 Sequence Identity: 38% (99 aa) IDVGDTIGHGEFGDVRLGTYKN-RKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLLRSRGRHALERRQ-- . .| | || |.|| ... ..|| | | | . ..||| | ||||.|| | || . .|..||||..| | . ||.. .| ... . LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIK-EGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREH-KHHFQKNMAI LMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSAS-GKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIFSFGRVP |. |.|.|| |||... .|||||||| | .|. | ||||||.. | . |||.|| .|| . | . |||||.||.| ||.|| |..| LLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMP YPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRLTT |.. .|| . .|.|.. |. |. .|...|.. | .. .||.| | |. .| YENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
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| Kinase | Y48G1C.2.AA | Fer | 283-533 | 30 | 3e-81 | 276.24 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 283-533 Range on HMM: 1-283/283 Sequence Identity: 30% (87 aa) IDVGDTIGHGEFGDVRLGT-----YK-----NRKVALKVSKRHGNGMLDS----LLDEAKFMVG-LSHPNLVTLVGVVLDDVNVYMITEYMANGNLIDLL .. |. .| | ||.|..|. .| ..||| || | ..... . .. ||..| ..||| | . || |. .. . |.. .|.| . | VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL RSRGRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDD-DLVAK--VSDFGLAKK----ANSQSHDSASGKFPIKWTAPEALRHSQFTTKSD . . .. .... .......|| ||.||...|||.||||.|... ... | .||||.... .. ... .. | ||.|.|||... ...|.| KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD VWSFGILLWEIFSFGRVPYPR----IPIQDV----VRYIEK-GYRMEAPEGCPPEIFKVMN-ETWALSAQDRPSFGQVLQRLT |||||...||||. | ||| . | .. |.| ||.| |...|||| ..| |. |||.. .. |.| VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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| Kinase | Y48G1C.2.AA | S_TKc | 283-533 | 26 | 4.1e-52 | 180.38 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 283-533 Range on HMM: 1-231/231 Sequence Identity: 26% (72 aa) IDVGDTIGHGEFGDVRLGTYKN--RKVALKVSKRHGNGMLDSLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMAN--GNLIDLLRSRGRHA---- .....||.| || |.... |. |.||.|. | .... | . . |||.|.| .| | ..||..||. . |.| |....|||| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP LERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVAKVSDFGLAKKANSQSHDSASGKFPIKWTAPEALRHSQFTT-KSDVWSFGILLWEIFS . . .. ||... |. |..|.|||| |.|||. . |..|||||.. . . ||| | .... |.|.||.|..|.| .. FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC FGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQ--------RLT |. |.| .| . . | .|| .. . ..||. ..|| -GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Y48G1C.2.AA | Pkinase | 283-532 | 23 | 6.5e-44 | 156.35 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 283-532 Range on HMM: 1-293/293 Sequence Identity: 23% (71 aa) IDVGDTIGHGEFGDVRLGTYKNRK--VALKVSKRHGNGM--LDSLLD--EAKFMVGLSHPNLVTLVGVVLDDVNVYMITEYMANG----NLIDLLRSRGR . .| .|| | || |.... |. ||.|. |.... . . ... |.. | |.||| |.| ... |. ..||..||. .| | |... . . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH HAL--ERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDLVA----KVSDFGLAKKA-NSQSHDSASGKFPIKWTAPEALR-HSQFTTKSDVWSF .. . ... ... |..|. |. |. |.|||| |.|.|.. . |..||||||.. . .. . . . ||| .| .. ..|.|.||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC GILLWEIFSFGRVPYPRI----PIQDVVRYIEKGYRMEAPEGCP-----------------------PEIFKVMNETWALSAQDRPSFGQVLQR--L |..|.| .. || |.| . | |.. . . .. .| .| .... ... ..||.. |.|| . GCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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