Gene Y47G6A.5 (Nematode worm)

Y47G6A.5

Species: Nematode worm
Alias: Y47G6A.5, Y47G6A_245.h, Y47G6A.5a, CE22093, aSWK406
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-4.1, WormBase Physical Map location: I: 3533823-3539158,

Classification

Group: TK
Family: Src
Subfamily: Src-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
Y47G6A.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 273 Kinase domain by global Sugen HMM Fasta, JSON
Y47G6A.5.AA Protein Genbank 662 None Fasta, JSON

Protein domain

Protein domains of Y47G6A.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 Y47G6A.5.AA SH3 185-242 22 8.5e-10 39.79 SMART 1-58 (58) Show / Hide 
Range on Protein: 185-242
Range on HMM: 1-58/58
Sequence Identity: 22% (13 aa)

KMLIVENRFLAQTPKEMSVEEGDVLYLIEQSNREWWYVASKSRQFKGFVPKSHVVYAE
.. ..   . ||.| |.|...||.....|... .||..  ..   .|..|...|   .
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 Y47G6A.5.AA SH3_1 193-235 31 2.4e-09 34.61 Pfam 6-49 (49) Show / Hide 
Range on Protein: 193-235
Range on HMM: 6-49/49
Sequence Identity: 31% (14 aa)

FLAQTPKEMSVEEGDVLYLIEQSNR-EWWYVASKSRQFKGFVPK
. ||.| |.| ..||....||.|.  .|| . ....  .|..| 
YQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 Y47G6A.5.AA SH3_2 195-240 18 3.7e-07 27.95 Pfam 11-68 (68) Show / Hide 
Range on Protein: 195-240
Range on HMM: 11-68/68
Sequence Identity: 18% (11 aa)

AQTPKE-----MSVEEGDVLYLI---EQSNREWWYV-ASKSRQFK--GFVPKSHV-VY
|. . |     .....|||...|   .... .||.. .....  .  |..| ..| ..
ATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 Y47G6A.5.AA SH2 247-331 35 4e-12 37.41 Pfam 1-81 (81) Show / Hide 
Range on Protein: 247-331
Range on HMM: 1-81/81
Sequence Identity: 35% (31 aa)

WFAGNISSILAEQRVMQPQLPIGSFLIRENS-KTDTFVLVVRSSH-NESPQAYIIYRRPNQEGFEIRDNHRPAVIHFGSLHQLVNHY
|. |.||   ||.. |.|. | |.||.|| . .   ..| ||    ... . |.| | .|  |. | ..|.     |.||..||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNG-GYYITGRHK-----FCSLQELVEHY
SH2 Y47G6A.5.AA SH2 245-337 32 6.1e-12 46.91 SMART 1-87 (87) Show / Hide 
Range on Protein: 245-337
Range on HMM: 1-87/87
Sequence Identity: 32% (31 aa)

EPWFAGNISSILAEQRVMQPQLPIGSFLIRE-NSKTDTFVLVVRSSHNESPQAYIIYRRP-NQEGFEIRDNHRPAVIHFGSLHQLVNHYSCEKVP
.||. ||||   |||  ..|  | |.||.|.  |.   .|| ||.   .  . |.| | . ..  ..           | || .|||||.  . .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK--GKVKHYRIRRNDDGKYYIDET-----WRRKFPSL-ELVNHYQHNPLG
Kinase Y47G6A.5.AA Src-Unclassified 372-644 58 3.6e-230 770.93 In-house 1-284 (284) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-284/284
Sequence Identity: 58% (165 aa)

VRRVKEIGRGQFGEVYLAKWKG-VDVAVKSLKPDHSEQLANTQFL--------EEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLT
|......||||||||...||.| ||||||...|.|||......||        .||....|..|||..||.|||....||.||||.|.|||||.||....
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

KTLPPIPLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFD
.....|..|||||||||||||..|.|||||||.||...|.|||||||||||.|...|||||.|||.|||||||....|.||.|.|..|.||||||||||.
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

EQIFNTKTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRP--ELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYF
...|..|.||||||||||||.|.|.|||.|......|||..|||..|.|  ...|||.|||..|.|.|.||.||||||.|..||
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase Y47G6A.5.AA Src 372-644 40 1.2e-146 493.49 In-house 1-255 (255) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-255/255
Sequence Identity: 40% (112 aa)

VRRVKEIGRGQFGEVYLAKWKG-VDVAVKSLKPDHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKTLPPIPL
.......|.||||||. ..|.| ..||||.|||..   .....||.||....||.|.....|.|||....|..|.||.|..||||..|.|          
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT---MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----------

MSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFNTKT
 ..|... .. .  ...||||.||.||......||||||||||||. .     ..||||||||| ....|..|........|.||.|||..... |..|.
-DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN-----VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKS

DVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYF
||||.||||.|| | |..||.|.... .|....||| .|.|. .||..||.... |.| ||..||||..|....
DVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Y47G6A.5.AA Pkinase_Tyr 372-644 37 1.2e-99 338.1 Pfam 1-270 (270) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-270/270
Sequence Identity: 37% (107 aa)

VRRVKEIGRGQFGEVYLAKWK------GVDVAVKSLKPDHSEQL-ANTQFLEEAKTLTKL-SHQNVIHLLAVCD-TDKP--YLIITEFMTNGSLLAWLQK
..  |..|.|.|||||...||      ...||||.||......      |..|||....| .|.|.. |..||   ..|  ..|..|.| .|.||  |.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

LTKTLPPIPLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENY-VMKTDNMLPWKWMAPE
            |. .. ..    ....|.|.||.||......||||||||.||.         ||..||||||     |..| ..... .|| ||||||
HR----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-----NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPE

CFDEQIFNTKTDVWSYGILLWEIGTLGKTP-YRGWDYEGTLEHL-SRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYF
|. . .|.||.||||.|.|.||| |.|..| | |.. |  .|..  .|| .|.||. || .|.   | | | || .||||  .   .
CINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase Y47G6A.5.AA TK 372-644 21 3.3e-98 329.84 In-house 1-486 (486) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-486/486
Sequence Identity: 21% (107 aa)

VRRVKEIGRGQFG---EVYLAKWKG---------------------------VDVAVKSLKPDHSEQLANTQ------------FLEEAKTLTKLS----
.. .|..|.||||   |||...|.|                           ..|||| ||...... .  .            |||||  . ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HQNVIHLLAVCDTD------------KPYLIITEFMTNGS----LLAWLQKLTKTLPPIPLMSEE----------------------------------
 |.|...|..||  .            .|..|..|.| .|.    |. .|.|  ..  . .  ...                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------TGRKNVLIGASISAQVASGMDYLSAN------KIVHRDLAARNVLVGTVSSNG------VPLVKVADFG---
                            ... ..     ...|.|.|| ||...      ..|||||||||.|||    .       .| .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARKTDVGDENYVMK-----------------------TDNMLPWKWMAPECFDEQI---------FNTKTDVWSYGILLWEIGTLG-KTPYRGW
     |||. . .|. |...                       .. .|| .||||||.....         | ||.||||.|.|.||| |.| ...| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DY---------EGTLEHLSRG--------------YVLPRPELVPD-------------YVYEDAFKICVHLDPRRRPTFDRLFKYF
.          .  .|.| ||              . .|.|.. ||              .|.|  . | |.||..||||. | ...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Y47G6A.5.AA TyrKc 372-644 34 2.5e-96 327.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-280/280
Sequence Identity: 34% (104 aa)

VRRVKEIGRGQFGEVYLAKWKGVDVAVKSLKPDHSEQLANTQFLEEAKTLTKL--SHQNVIHLLAVCDTD-------KPYLIITEFMTNGSLLAWLQKLT
..  |..|.|.|||||...|| ..||||.||.|.        |..||. ..||  .|.|.. |..|| ..       .|..|..|.| .|.|.  |.|  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

KTLPPIPLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVG------DENYVMKT--DNM--LP
..              ..    |.. |.|.||.||. ....||||||||.|||         ||..||||.|. . .      .. |..|.  .    ||
PK-------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

WKWMAPECFDEQIFNTKTDVWSYGILLWEIGTLGKTPYRG-----WDYEGTLEHLSRGYVLPRPEL--------VPDYVYEDAFKICVHLDPRRRPTFDR
 .||||||... .|.||.||||.|...||| |.|..|| |      . .  .|.. .|| .|.|.          || .|.   | | | ||  ||||  
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSE

LFKYF
. ..|
IHECF
Kinase Y47G6A.5.AA UTK 372-644 31 7.8e-80 271.53 In-house 1-296 (296) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-296/296
Sequence Identity: 31% (97 aa)

VRRVKEIGRGQFGEVYLAKWKG-------VDVAVKSLKPDHSEQLANT---QFLEEAK---TLTKLS-HQNVIHLLAVCDTDKPYLIITEFMTNGSLLAW
|.. ...|.|.||||..|...        .||||| ...... | . .   .|.|||.    . ... |.||. |..||  ..| .|.||.| ||.|.. 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LQKLTKTLPPIPLMSEETGRKNVLIGAS---ISAQVASGMDYLSANKIVHRDLAARNVLVGTVS---SNGVPLVKVADFG---LARKTD-------VGDE
|.. ..|.|         ..   |   .    ....|.|| ||.  ..|||||||||.||.  .        ..|.||||   ..|           .. 
LRRHRPTPP---------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWH-CMMVCKIADFGRGGMSRRVNTFHFSNRYWES

NYVMKT-DNMLPWKWMAPECFDEQ-IFNTKTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRG--YVLPRPELVPDYVYEDAFKICVHLDPRRRPTF
.|.|.. ....|..|||||.....  | ||.||||.|...||| | |..|| |.  . ... ...|  | .|.|. .|. || .  . | | ||..||.|
YYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVY-RLMHRCWHYDPQERPDF

DRLFKYF
..| . .
EDLVQQM
Kinase Y47G6A.5.AA TK-Unique 372-644 30 7.3e-72 245.05 In-house 1-294 (294) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-294/294
Sequence Identity: 30% (91 aa)

VRRVKEIGRGQFGEVYLAKWKG--------VDVAVKSLKPDHSEQLANTQFLEEAKTLTKLS-HQNVIHLLAVCDTDK-PYLIITEFMTNGSLLAWLQKL
..  ..||.|.||.|. .. .|        . |||| || |.. ..   .|| |.. . .|  |.|....| .| ..  | .|| |.. .|.|.  |.. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK-DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

T-KTLPP-------IPLMSEETGRKNVLIG----ASISAQVASGMDYLSA--NKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMK-
  .. ..       . ..... .  .  |     ...  |.|.|| ||.    |||||||.|||||..         .|..|||.||...  .. |.|. 
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTE-----DKVCKICDFGMARDVYT-NGVYSMMC

TDNMLPWKWMAPECFD--EQIF-NTKTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELV-PDYVYEDAFKICVHLDPRRRPTFDRLFK
. ...| .||||| .   .... .||.||||.|.|.||| |||..||.| . .  .|.. .|| .|.|| . .. .|..    | ...|  ||.|. . .
SQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKS-CWQWEPEERPSFRQIKH

YF
 .
RL
Kinase Y47G6A.5.AA Frk 372-648 39 2.3e-69 236.77 In-house 1-260 (260) Show / Hide 
Range on Protein: 372-648
Range on HMM: 1-260/260
Sequence Identity: 39% (109 aa)

VRRVKEIGRGQFGEVYLAKW-KGVDVAVKSLKPDHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKTLPPIPL
.. ....| ||||||.  .|   . |||| |||     .  . || ||. . || |  .|.| |||  ..| .|||| | .|||. .|| ....   . .
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKP---GTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQM

MSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDE-NYVMKTDNMLPWKWMAPECFDEQIFNTK
          |.   ..||||.|| ||     .||||||||||||   .     .|.|||||||   . .|  |  ...  .| || |||    . | .|
Q--------QLV--DMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNI-----CKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIK

TDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYFDEIN
 ||||.|||| || | |. || |      |. ...|| .|.|   |  .||     | | ||..||||. |   ...  
SDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYE-IMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Y47G6A.5.AA Abl 372-644 38 2.8e-66 219.98 In-house 1-252 (252) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-252/252
Sequence Identity: 38% (107 aa)

VRRVKEIGRGQFGEVYLAKWK--GVDVAVKSLKPDHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKT-LPPI
.   . .| ||.|||| . ||  .  ||||.|| |   ...  .||.||  . .. |.|...|| ||  . |. ||||||..| || .| .  .. ||..
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKED---TMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELPAV

PLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFNT
 |.              . .|.||||.|| ... .|||||||| |||        .||||||||||   . |. |  .     | || |||    . | .
VLL-------------YMATQIASGMSYLEKRHFIHRDLAARNCLVGEHH-----IVKVADFGLARM--MKDDTYTAHAGAKFPIKWTAPESLAYNKFSS

KTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYF
| ||| .|.||||| | | .|| | | .   . | .|| . |||  |. |||   . | . ..  ||.|  . . .
KSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYE-LMRQCWQWSHTDRPSFKEIHHAM
Kinase Y47G6A.5.AA Tec 372-646 37 2.3e-63 216.84 In-house 1-254 (254) Show / Hide 
Range on Protein: 372-646
Range on HMM: 1-254/254
Sequence Identity: 37% (104 aa)

VRRVKEIGRGQFGEVYLAKWKG-VDVAVKSLKPDHSE-QLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKTLPPIP
   .||.|.|||| | |.||..  |||.| .|    |       |.||||. .|||| . . |  ||   .|  |.||.|..|.|| .| .  ...    
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIK----EGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHF----

LMSEETGRKNV--LIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFN
       .||.  |.  ..  .|  || ||  .. .|||||||| |||   ...|  |||.|||..|   | |  |.  .    | || .|| |    . 
-------QKNMAILL--EMCQDVCEGMAYLERHCFIHRDLAARNCLVG---DQCV--VKVSDFGMTRY--VLDDQYTSSVGTKFPVKWCPPEVFHYSRYS

TKTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYFDE
 | |||..|.| ||. ..|| ||   .   . || |.|. | ||.| ....|.   . | |  |  |||| .| .   |
SKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQ-IMYHCWHEKPEERPTFQQLLRQITE
Kinase Y47G6A.5.AA Src-Echino1 372-644 38 4.1e-63 215.99 In-house 1-252 (252) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-252/252
Sequence Identity: 38% (105 aa)

VRRVKEIGRGQFGEVYLAKWKG-VDVAVKSLKPDHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWLQKLTKTLPPIPL
.|  |.||.|..|||.   |.|  .|||| ||.     ... .|| ||  . |. |.... . |||   .|  |.|| | ||.|...|.           
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKT---MSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLK-----------

MSEETGR-KNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFNTK
  .. ..   .     . |..|||||||    .|||||||||||||.       ..|.|||||||   . .. |. |    || || |||      |  |
--RGKCKHVKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGN-----VCKIADFGLARM--MQKDVYCGKQGAKLPIKWTAPEAALYGRFTIK

TDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYF
 ||||.|||. |. | |. ||.|      |... ||| .|...  || .|. .   | | ||..||||. | ..|
SDVWSFGILMTEMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Y47G6A.5.AA Fer 486-645 31 1.7e-47 159.88 In-house 116-283 (283) Show / Hide 
Range on Protein: 486-645
Range on HMM: 116-283/283
Sequence Identity: 31% (55 aa)

ISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVK--VADFGLARKTDVGDENYVMK-TDNMLPWKWMAPECFDEQIFNTKTDVWSYGILLWEI
...|.|.||.|| .....|||.||||.|.    ....  .|  ..|||..|..... . | || .  ..| .|.|||...  |...||||||.|...|||
MCYQAACGMEYLHSKNCIHRDIAARNCLY----HKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTDVWSFGVMCWEI

GTLGKTPYRG---------WDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFKYFD
 | |..|| |         .. .        || .| |. .|. ...   | | . ||  |||.. . . . 
FTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase Y47G6A.5.AA S_TKc 372-644 21 5e-40 140.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

VRRVKEIGRGQFGEVYLAKWKG--VDVAVKSLKPDHSEQLANTQFLEEAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTN--GSLLAWLQKLTKTLPP
 . ...||.| ||.||....|.    ||.| .|          ... | . | |  | |...|. |... . . ...|.. .  |.|.  ..|  .  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

IPLMSEETGRKNVLIGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAPECFDEQIFN
 |.   ..        ... .|......|.  ..|.||||   |.|. .        .|..||||||.           |       .|||| .    ..
FPFPE-HA--------RFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYG

T-KTDVWSYGILLWEIGTLGKTPYRGWDYEGTLEHLSRGYVLPRPELVPDYVYEDAFKICVHLDPRRRPTFDRLFK---------YF
. | |.|| |..|.|  . |..|..  ... .....             .    |  . | . ||..|||   ...         .|
KCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y47G6A.5.AA Pkinase 372-644 21 5.5e-32 114.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 372-644
Range on HMM: 1-293/293
Sequence Identity: 21% (69 aa)

VRRVKEIGRGQFGEVYLAKWKGVD--VAVKSLKPDHSEQLANTQFLE--EAKTLTKLSHQNVIHLLAVCDTDKPYLIITEFMTNG----SLLAWLQKLTK
 .... ||.| ||.||....||    |||| .| .| .   . . .   |.. . .|.| |.. |. .. ... . ...|.. .|    .| ....    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

TLPPIPLMSEETGRKNVL-----IGASISAQVASGMDYLSANKIVHRDLAARNVLVGTVSSNGVPLVKVADFGLARKTDVGDENYVMKTDNMLPWKWMAP
             |....        ..  |...|..|. ...|.||||   |.|.     ..   ||..|||||.. |    |..  |.      .|||
------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAP

ECFD-EQIFNTKTDVWSYGILLWEIGTLGKTPYRGW----DYEGTLEHLSRGYV--LPRPELVPDYVY-----------------EDAFKI---CVHLDP
|     |   .| |.||.|..|.|  . |..|..|     .    .. . |     |....  .. ..                 |.. ..   | ..||
EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

RRRPTFDRLFKY--F
 .|||.. ...   |
KKRPTAEQILQHPWF
Kinase Y47G6A.5.AA Fer 372-460 32 5.1e-18 58.04 In-house 1-102 (283) Show / Hide 
Range on Protein: 372-460
Range on HMM: 1-102/283
Sequence Identity: 32% (33 aa)

VRRVKEIGRGQFGEVYLA---------KWKGV---DVAVKSLKPDHSEQLANTQFLEEAKTLTK-LSHQNVIHLLAVCDTDKPYLIITEFMTNGSLLAWL
|   | .|.| |||||..         ||  |   .|.|| .| ...       |. ||. . . ..| ||. .  ||  . |..|. ||...|||.  |
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QK
.|
KK