Gene Y116A8C.24 (Nematode worm)

Y116A8C.24

Species: Nematode worm
Alias: Y116A8C.38, Y116A8_02435.1, Y116A8C.24, CE23332, aSWK338
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: IV:27.79, WormBase Physical Map location: IV: 17070827-17068823

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
Y116A8C.24.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON
Y116A8C.24.AA Protein Genbank 521 None Fasta, JSON

Protein domain

Protein domains of Y116A8C.24.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 Y116A8C.24.AA SH2 68-155 27 1.3e-11 45.85 SMART 1-87 (87) Show / Hide 
Range on Protein: 68-155
Range on HMM: 1-87/87
Sequence Identity: 27% (25 aa)

VSYYHGMVARDLVESKLTRC----GDYLIRATDNRIMEFEFILSFFNKKRIHSHLTIKCDVEAGKWALGLLSVNQFSSVVDLTNFYKTNPIG
  .|||.. |. .|..| .     ||.|.|  ..  .  ...||.. | .   |  |... . ||. .. ..  .|.|. .| |.|..||.|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES--NPGDYVLSVRWK-GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Y116A8C.24.AA Fer 182-455 30 2.1e-100 339.88 In-house 4-283 (283) Show / Hide 
Range on Protein: 182-455
Range on HMM: 4-283/283
Sequence Identity: 30% (89 aa)

DDLLGTGNFSDVFRG--KIEL--ENQMVN--VALKTTKLLDDTMDPTKNVKANKI-KKEMIQEAEVMSQ-LRHANVTSFFGIAVDRLPILLIIEFCNGGN
.. || |.| .|..|  .. .  . ..|.  || |..|.  .        .|.|  .||. .|| .| . . | ||  |.|..||. ||....||||||.
GKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCE--------DATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGS

LQGHLIKFGDR-IGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVK---LSDFGMGLKVRRNESAKKVAEDDDGKENKEPKLPVRWMSPE
|. .| | ... . .||.. ....|..|..|.|.. . ||||||||||.. ....|   .|||||  . .......| .|       |. |.|.||..||
LDSYLKKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE-------KACKVPIRWLAPE

LVDTPDAFSKMSDMWSLGILAYEIFTNATKPFFN---------LDDTDVMQTVKSGKHPPLPLSMGPDLIRLLK-DVLVAAPTQRTTADKFYNELH
 ..|   .|...|.|| |....|||||. .|...         ........ .|.|...|.|..| |....... .. ...| .|.|.......|.
TWQTGI-YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase Y116A8C.24.AA TK 183-454 15 8.5e-59 195.39 In-house 5-486 (486) Show / Hide 
Range on Protein: 183-454
Range on HMM: 5-486/486
Sequence Identity: 15% (76 aa)

DLLGTGNFS---DVFRGKIEL-----------------------ENQMVNVALKTTKLLDDTMDP-TKN---------VKANKIKKEMIQEAEVMSQLR-
. || |.|    .|..|. .                        |.. . || |. |. |.. .   .          .       .  .|||.|.... 
KKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGE-------DFLEEAEEMKMMCH

----HANVTSFFG-------------IAVDRLPILLIIEFCNGGN----LQGHLIKFGDR----------------------------------------
    | |. ...|             . |.. |.... |....|.    |. .| |  ..                                        
SLGHHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPE

-----------------------------------IGTNERFLYLHDASAGLNYIHAM------SITHRDIAARNCLISVNGF-----------VKLSDF
                                   . . ..  . .....|. |.|..       . |||.||||||.. |.            .|..||
EQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADF

G--------MGLKVRRNESAKKVAEDDDGK-----ENKEP-----------KLPVRWMSPELVDT--------PDAFSKMSDMWSLGILAYEIFTNATKP
|        .  .. ...   .. . ..|.     |   |           |||.|||.|| ...           |.  ||.||.|.| .||||.. .|
GLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFED-DPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

FFN-LDD---------TDVMQTVKSG--------------KHPPLPLSMGP-------------DLI-RLLKDVLVAAPTQRTTADKFYNEL
.   ...         ..||. ...|                .| |  . .             ... .|...   . | .| | .  ...|
YYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Y116A8C.24.AA TyrKc 181-454 23 1.7e-52 181.66 SMART 3-280 (280) Show / Hide 
Range on Protein: 181-454
Range on HMM: 3-280/280
Sequence Identity: 23% (73 aa)

KDDLLGTGNFSDVFRGKIELENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQL--RHANVTSFFGIAVDR-------LPILLIIEFCNG
... || |.|  |..|.       ..|| |. |                 ......||..|..|  .| |.  ..|....         |.... |.. .
LGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA--------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

GNLQGHLIKFGDRIGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVAED-------DDGKENK--EPK--
|.|. .| | .... . .   . .....| .|.| . . |||.||||||.. |. || ||||.         .... .|       |  .  .    |  
GDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL---------SRDIYDDDQQGESKDYYRKKEHKGGKTM

LPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIFTNATKPFFN-----LDDTDVMQTVKSGKHPPLPLS--------MGPDLIRLLKDVLVAAPTQRTTA
||.|||.||       |.  || || |.. .||||.  .|  .     .....|.. ||.|. .| | .        . ... .. |.   . | .| | 
LPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTF

DKFYNEL
   . ..
SEIHECF
Kinase Y116A8C.24.AA Pkinase_Tyr 181-422 27 8.3e-50 169.31 Pfam 3-238 (270) Show / Hide 
Range on Protein: 181-422
Range on HMM: 3-238/270
Sequence Identity: 27% (70 aa)

KDDLLGTGNFSDVFRGKIE--LENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQL-RHANVTSFFGIAV-DRLP--ILLIIEFCNGGNL
..  || |.| .|..|.     .|. . || |. |  ...|..        .......||..|.|| .| |. .. |. . .. |  |... |.. .|.|
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQN------CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

QGHLIKF---GDRIGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVAEDDDG-KENKEPKLPVRWMSPEL
  .| |    .... . .   . .. ..|..| ... . |||.||||||.. |..|| .|||.         |. . .||   .  .. |||..||.|| 
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL---------ARDIYNDDYYYRKRGGGKLPIKWMAPEC

VDTPDAFSKMSDMWSLGILAYEIFTNATKP-FFNLDDTDVMQTV-KSGKHPPLP
  .   |.  || || |.| .||||   .| . ......|.. . ..|   | |
INYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCP
Kinase Y116A8C.24.AA TK-Unique 179-454 23 5.2e-47 160.15 In-house 1-294 (294) Show / Hide 
Range on Protein: 179-454
Range on HMM: 1-294/294
Sequence Identity: 23% (73 aa)

SPKDDLLGTGNFSDVFRGKIEL----ENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQLR-HANVTSFFGIAVDRL-PILLIIEFCNGG
.  .|..|.|.|. |.||...     ... ..||.|. |   .  |          |... .|...|..|  | |. ...|. ..   | ..|.|.| .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTD----------KQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG

NLQGHLIKFG-DRIGT----------------------NERFLY--LHDASAGLNYIHA--MSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAK
|||..| ... .. ..                      ....||  . .   |..|..   . |.|||..|||.|.. .. .|..||||  .|.      
NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-----

KVAEDDDGKENKEPKLPVRWMSPELVD--TPDAFSKMSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSGKHPPLPLSM-GPDLIRLLKDVLVAAPT
   . .  .. .. ..|.|||.||     .  ...  || ||.|.| .||||.   |. .....|.|. .. |. .|.| .   ...  |.| ..   |.
---NGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPE

QRTTADKFYNEL
.| . ..  ..|
ERPSFRQIKHRL
Kinase Y116A8C.24.AA UTK 183-435 22 1e-40 137.05 In-house 5-277 (296) Show / Hide 
Range on Protein: 183-435
Range on HMM: 5-277/296
Sequence Identity: 22% (65 aa)

DLLGTGNFSDVFRGKIELEN---QMVNVALKTTKLLDDTMDPTKNVKANKIKK-----EMIQEAE---VMSQLR-HANVTSFFGIAVDRLPILLIIEFCN
..|| |.| .|.... . ..   . . ||.|. .           ..|.. ..     . . ||    .|.|.. | ||  . |. ..  |.....|.. 
RQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ-----------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYME

GGNLQGHLIKFGDRIG-------TNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNG-------FVKLSDFGMGLKVRRNESAKKVA-------E
.|.|.  | . ..  .         .|  .  | ..|..|.| . . |||.||||||.  ..       ..|..||| |        .. |.       .
NGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRG-----G-MSRRVNTFHFSNRY

DDDGKENKEP--KLPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSG--KHPPLPLSMGPDLIRLLKD
...  ... .  ..|.|||.|| ..    |.  ||.||.|.. .||.|.. .|. .. . .| . |  |   ..| | ... .. ||...
WESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHR
Kinase Y116A8C.24.AA TKL 185-454 19 2.5e-35 123.71 In-house 1-364 (364) Show / Hide 
Range on Protein: 185-454
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGTGNFSDVFRGKIELENQMVN-------VALKTTKLLD------------------DTMDPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDR
.| | |. |..||   ..  .        || |. |  .                  | |   .. .| ..... ..|. .||.||| |. .| |.. . 
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSD-M-QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCP

LP-------------ILLIIEFCNGGNLQGHLIKFGDRIGTNERFLYLHDASAGLNYIHAMS--------ITHRDIAARNCLISVNGF------------
 .             . .. |.| ||.|  .|.        . |.   .|.. |.|| |.|         | |||.  .|.|.  |.             
PCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--VKLSDFGMGLKVRRNESAKKVA---------EDDDGKENKEPKLPVRWMSPELVD----TPD-----------AFSKMSDMWSLGILAYEIFTNATKP
  .|..|||    . .... .. .           . .| .  .    |||.||. .    ...            .|. .|..| ||. .||.|  . |
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-P

FFNLD-DTDV---------MQTVKSGKHPPLP------------LSMGPDLIRLLKDVLVAAPTQRTTADKFYNEL
..... .. .         |. .. |..||.|             .. |....|..|   . |..| ....   .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase Y116A8C.24.AA CTKA 296-454 31 9.8e-32 103.81 In-house 139-290 (290) Show / Hide 
Range on Protein: 296-454
Range on HMM: 139-290/290
Sequence Identity: 31% (51 aa)

DASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVAEDDDGKENKEPKLPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIFT
.. || ||  .| . ||| |.||||.     .|..||| | . .| ||   .         .   .|||||.|| . .   ||  || |. |.| .||..
QIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHG-RTLRTESQYYYVS-------SQRVMPVRWMAPEALCF-GKFSCASDVWAFGVLLWEIMS

NATKPFFNLDDTDVMQTVKSG--KHPPLPLSMGPDLIRLLKDVLVAAPTQRTTADKFYNEL
 . ||.  . |  | | . |.  .  |.|..    |. . .  .  .| || |      .|
MGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase Y116A8C.24.AA Pkinase 179-454 20 9.4e-31 109.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 179-454
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

SPKDDLLGTGNFSDVFRGKIELENQMVNVALKTTKLLDDTM-DPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNGG----N
  .   .| |.|. |....   ...   ||.|. |. .. .  .  ....        .|...|  |.| |.  ....  |.  | .. |.|.||     
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRL--------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMD

LQGHLI-KFGDRI--GTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFV----KLSDFGMGLKVRRNESAKKVAEDDDGKENKEPKLPVRWM
|  ..  . . ..    .|   |.     ||.|.|.|.| |||.   |.||. || .    |..|||   ...             .  .. .    ..|
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYM

SPELVDTPDAFSKMSDMWSLGILAYEIFTNATKPFFNL----DDTDVMQTVKSGKHPPLPLSMG-----------------------PDLIRLLKDVLVA
.||.. .    .. .||||.|.. || ..    || .     .  | || ..  ..|||. .                         .... ..|. |  
APEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

APTQRTTADKFYNE--L
 |..| ||.   .   .
DPKKRPTAEQILQHPWF
Kinase Y116A8C.24.AA Src 185-454 29 9e-30 98.29 In-house 7-255 (255) Show / Hide 
Range on Protein: 185-454
Range on HMM: 7-255/255
Sequence Identity: 29% (82 aa)

LGTGNFSDVFRGKIELENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNGGNLQGHLIKFGDR
||.|.| .|. |.    |. ..|| ||  |  .||.|.             |||..| .||| .. . . .  .  ||. . |. . |.|.  | |  |.
LGQGQFGEVWMGYW---NGNTKVAVKT--LKPGTMSPEAFL----------QEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--DG

IGTNERFLYLHDASA----GLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVA-EDDDGKENKEPKLPVRWMSPELVDTPDAFSK
 | . ..  | | .|    | .|. .| . ||| |||| |.. |  .|  |||          |. .  .||     .. |.|..|. || ..    |. 
EGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGL---------ARLIKEDDDEYCARHGAKFPIKWTAPEAINY-GRFTI

MSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSGKHPPLPLSMGPDLIR-LLKDVLVAAPTQRTTADKFYNEL
 || || ||| .||.|    |    .  .|.| |. | . | |    . |   ...    . | || | .  .. |
KSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Y116A8C.24.AA Frk 176-458 26 1e-29 99.92 In-house 1-260 (260) Show / Hide 
Range on Protein: 176-458
Range on HMM: 1-260/260
Sequence Identity: 26% (77 aa)

IKYSPKDDLLGTGNFSDVFRGKIELENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNGGNLQ
|..  .   ||.| | .|. |   | |. . ||.||  |   ||||          .....|| .| .|||. . . . .     ||..| |    | ||
IQLIRR---LGSGQFGEVWEG---LWNNTTPVAVKT--LKPGTMDP----------NDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQ

GHLI---KFGDRIGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVAEDDD--GKENKEPKLPVRWMSPEL
 .|    . | ..  ..         ||. |.  .   |||.|||| |.  .  .|. |||.         |. .  |.        . ..|..|  || 
EYLQAINDKGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGL---------ARVLMKDNEDIYESRHGARFPIKWTAPEA

VDTPDAFSKMSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSGKHPPLPLSMGPDLIRLLKDVLVAAPTQRTTADKFYNELHVLC
. . . |.  ||.|| ||| .|| |    |.  . . .|.| |. |   | |    . |  .. .   . | .| | .     |    
ANY-NKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Y116A8C.24.AA S_TKc 179-457 17 1.1e-29 105.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 179-457
Range on HMM: 1-231/231
Sequence Identity: 17% (52 aa)

SPKDDLLGTGNFSDVFRGKIELENQMVNVALKTTKLLDDTMDPTKNVKANKIKKEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNG--GNLQG
  . ...| | |. |....         ||.|  |                  . ...| ..... .| |.  .... .|   . .. |.|.|  |.|  
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFD

HLIKFGDR-----IGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGMGLKVRRNESAKKVAEDDDGKENKEPKLPVRWMSPELV
.. | | .     .   .   |..    .|.|.| . | |||.   | |..    .|..|||.  ..                  .       .|.||..
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL

DTPDAFSK-MSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSGKHPPLPLSMGPDLIRLLKDVLVAAPTQRTTADKFYN-E-----LHVL
     ..|  .|.||.|.. || ..    ||   ..  ... ..            |... ...  |.  |..| || .  . |        .
----GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Y116A8C.24.AA RTKC 232-334 33 2.6e-20 63.61 In-house 46-147 (261) Show / Hide 
Range on Protein: 232-334
Range on HMM: 46-147/261
Sequence Identity: 33% (35 aa)

KEMIQEAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNGGNLQGHLIKFGDRIGTNERFLYLHDASAGLNYIHAMSITHRDIAARNCLISVNGFVKLSD
.|   || || |..|.||    |.     ||| ..|||  | | ..| . .  .    . ..  ....|.  ||.    |||.|||| |.|     |..|
QELLEEAAVMAQFEHPNVVHLIGVVTVGKPILVVLEFCERGSLKSYLMNNP-DCTEHQKVRFCYQCASGMEHIHSFGFIHRDVAARNVLLSSDLTCKVAD

FGM
||.
FGL
Kinase Y116A8C.24.AA Trk 361-454 26 1.4e-14 45.8 In-house 182-275 (275) Show / Hide 
Range on Protein: 361-454
Range on HMM: 182-275/275
Sequence Identity: 26% (25 aa)

LPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIFTNATKPFFNLDDTDVMQTVKSGKH-PPLPLSMGPDLIRLLKDVLVAAPTQRTTADKFYNEL
||.||| || .     |.  || ||.|.   |.||    |.. |  . | . .  |.| .  |    ...  ..       |.|| .. . .. .
LPIRWMPPESI-MYRKFTYESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase Y116A8C.24.AA Trk 299-334 47 2.4e-11 34.63 In-house 128-163 (275) Show / Hide 
Range on Protein: 299-334
Range on HMM: 128-163/275
Sequence Identity: 47% (17 aa)

AGLNYIHAMSITHRDIAARNCLISVNGFVKLSDFGM
.|. |.   .. |||.|.||||.  |  || .||||
SGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGM
Kinase Y116A8C.24.AA RTKC 361-397 56 2.6e-11 33.44 In-house 169-204 (261) Show / Hide 
Range on Protein: 361-397
Range on HMM: 169-204/261
Sequence Identity: 56% (21 aa)

LPVRWMSPELVDTPDAFSKMSDMWSLGILAYEIFTNA
||||| .||  |    ||. || |..||| |||.|.|
LPVRWTAPEALDD-RKFSEKSDVWAFGILMYEIYTKA
Kinase Y116A8C.24.AA Trk 237-278 33 2e-06 17.77 In-house 51-92 (275) Show / Hide 
Range on Protein: 237-278
Range on HMM: 51-92/275
Sequence Identity: 33% (14 aa)

EAEVMSQLRHANVTSFFGIAVDRLPILLIIEFCNGGNLQGHL
|||.. .| | ..  |.|. .|  |.|.. |. . | |.  |
EAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYL