Gene W04B5.5 (Nematode worm)

W04B5.5

Species: Nematode worm
Alias: aSWK011, W04B5.5, CE20142
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: III:-15, WormBase Physical Map location: III: 2413732-2406772

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
W04B5.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 278 Kinase domain by global Sugen HMM Fasta, JSON
W04B5.5.AA Protein Genbank 320 None Fasta, JSON

Protein domain

Protein domains of W04B5.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase W04B5.5.AA PDK1 26-303 45 5.8e-201 622.01 In-house 1-307 (307) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-307/307
Sequence Identity: 45% (141 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQ
....|..||||.|||||||.||.|||||...|.||| ||.|...|.|.|.|||||.......|.|.|||||.||.||||...|||||||...|||...|.
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

KQPDSKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSS---KFLSDYQKIQ----------ENPVEE---EQPTGRRSSFV
|||...|.....|.|||....||||.|..||||||.|..|.|...|..||.||||..   |.|..||..|          .|....   |....|..|||
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GTAFFVTPELLTGSEMSPSSDLWAFSVTLYLFLTGIYPFNDM-----SEYLVFRRIQDILYTFSEDFP-DENAKNLIERLLVKEQKSRLTS-------QE
|||..|.|||||..|..||.|.||.....|....|..||..|     .||..|..|... |.|...|. ...||.|...|||.....||||       |.
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ

IKEHKFF
||.|.||
IKAHPFF
Kinase W04B5.5.AA AGC 26-303 24 1.9e-117 304.78 In-house 1-395 (395) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-395/395
Sequence Identity: 24% (99 aa)

YSVEKEVGEGSFSTVYLARRKEPKN--DENPEVALKICLKRL-ILKNK--MVPYIHRE------------KEALALISREENA------HPGIVT-LYAT
. . | .|.|||..|||.|.|. ..  | .   |.|.. |.  |...|  || ....|            .. |.... .. .      || ||  |. .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTH-NHPIKSHHPFIVKILHYS

FQDSES--LYFVLEYAK----------YGDLCTLMQKQ-PDSKFNVADSRYYAAN-------LLSALEHIHK-LGIIHRD-VKADNLLVKSDGRIMLTDF
||| .   ||||.||..           ..| . .|..    .|.   .|.|||        ...|||..|. .|||||| .| .|.|  .|| |.||||
FQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF

GSSKFLSDYQ---------------------------------KIQENPVE-EEQPTGRRS------SFVG--TAFFVTPELLTGSEMSPSSDLWA--FS
|..| . ...                                 . ..| .. | ..| | .      .|.|  |. .. || |     ... | |.  . 
GLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNN-MSQE-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

VTLYLFLTGIYPFNDMS----------EYLVFRRIQ--------DILYTFSE-------DFPDENAKNLIERLLVKEQKSRLT----------SQEIKEH
. .| .|||. ||.. .          .. .| .|.        .. . | |       .. ...||.||..||.|. . ||.           .|||.|
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

KFF
..|
PWF
Kinase W04B5.5.AA S_TKc 26-303 27 4.8e-76 259.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-231/231
Sequence Identity: 27% (81 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKY--GDLCTL
| . ...|.|.|..||..| |.     . .||.||              | || . |         || ||.|| .||| ..||.|.||.    ||| ..
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK----------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

MQKQPD----SKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFFVTPEL
..|..     ..|.  . |.|.. ...|||..|..||||||.| .|.|. .  .|...|||....|                    ..|.|| ... ||.
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------TTFCGTPWYMAPEV

LTGSEMSP-SSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRIQDILYTFSEDFPDENAKNLIERLLVKEQKSRLTSQEIKE-------HKFF
|     .. ..| |.. ..|| .|.|  ||    ....|..|            .. ||..|...|.|. . |.|  |. .       | .|
L---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase W04B5.5.AA CAMK 31-303 17 8.9e-66 210.67 In-house 1-425 (425) Show / Hide 
Range on Protein: 31-303
Range on HMM: 1-425/425
Sequence Identity: 17% (76 aa)

EVGEGSFSTVYLARRKEPKNDEN--------PEVALKICLKRLILK-----------NKMVPYIHREKE----ALALISREENA------------HPGI
. |.|||..|.|...|. ...|.         .|| ||  |. . .            ..    ||...     .. . || .             || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VTLYATFQDSES-------------------LYFVL---EYAKYG----DLCTLMQKQPD-------------SKFNVADSRYYAANLLSALEHIHKLGI
. || ...|..                    .|.|.   ||.  |    ||    .....              .|. .. |.|   ..||....|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDVKADNLLVKSD-----------------GRIMLTDFGSSKFLSDYQ-------KIQENPVEEE-----QPTGRRSSFVGTAFFVT-PELLTG----
.||| | .|.|. ..                 . | ..||| .... . .       . ... . ..      ..   . |.||  ..  ||.| |    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------SEMSPSSDLWAFSVTLYLFLTGIYPFNDM-------------SEYLVFRRIQDILYTFSEDF-----------------------PDENA
             .|..| |.  | ||  |.| .||..              ..|  |..|.   |.| ...                        .. .
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KNLIERLLVKEQKSRLTSQEIKEHKFF
|.|| ..|... . |.| .....|...
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase W04B5.5.AA Pkinase 26-303 25 9.8e-65 226.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-293/293
Sequence Identity: 25% (81 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIH-REKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYG----DL
| ... .|.|||..||....|        .||.||  || . ..| .  .. .| . .. ..     || ||.|| .|.|. ..|.|.||.  |    ||
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

CTLMQKQPDSKF--NVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRI----MLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFF
..... . . .|     . . |.  .|..||..|. ||||||.| .|.|....| |     ..|||..|...            . . .  ..|.|| ..
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------Y-NNS-MTTFCGTPWY

VTPELLT-GSEMSPSSDLWAFSVTLYLFLTGIYPFNDM------SEYLVFRRIQDILYTFSEDFPD--------------------ENAKNLIERLLVKE
. ||..  |.. .|..| |.. ..|| .|.|  || .       ... ...|| .  . |... ..                    |..| .|...| | 
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

QKSRLTSQEIKEHKFF
 |.|.| ..|..|..|
PKKRPTAEQILQHPWF
Kinase W04B5.5.AA Ciliate-E2 26-303 21 2.7e-58 198.72 In-house 1-365 (365) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-365/365
Sequence Identity: 21% (82 aa)

YSVEKEVGEGSFSTVYLARRKEPKN-------------------DENPEVALKICLKRLILKNKMVPYIHREKEALA--LISRE-----ENAHPGIVTLY
| . |  |.|.|..||...... ..                   . . ..|.||  |. |   |.. .| ||..      |  |     .. || |. .|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKI-NEKNILEQLNHPNIIKMY

ATFQ--DSESLYFVLEYAKYGDLCTLMQKQPDS---------KFNVADSRYYAANLLS---------------ALEHIHKLG-IIHRDVKADNLLVKSDG
 .||  | ...|.|.||...|||  ...... .         .|.    .|. . .|.               |||..|. . ||||| | .|.|.    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RIMLTDFGSSKFLSDY----------QKIQENPVEEEQPTG---------RRSSFVGTAFFVTPELLTGSE---------MSPSSDLWAFSVTLYLFLTG
 | ..||| ||...|           .....  ....  .|            ...||. .. || | | .          . ..|.|.. |.|| .|.|
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

IYPFNDMSEYLVFRRIQDILYTFSEDF-----------------PDENAKNLIER----LLVKEQKSRLT-SQEIKEHKFF
 .||        .. |..  . |.. .                  ....|.|| .    .|.|... |.|  ..|..|..|
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase W04B5.5.AA RSK 30-303 29 1.2e-52 181.25 In-house 2-278 (278) Show / Hide 
Range on Protein: 30-303
Range on HMM: 2-278/278
Sequence Identity: 29% (86 aa)

KEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKM-VPYIHREKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQKQP
|. |.|..  |.| |... . | . . | |.  |. | ...  . .  .| . |...    . || ||||. .||. . || ..|| . |.| |  ||. 
KVLGQGGYGKVFLCRKCTHH-DTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERC----QQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK

D-SKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKS---DGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFFVTPELLT---
    |   . ..|.|.. .|.||.|..|||||| | .| |  .   .|.|.||||| .| .         . ...|.|    .|..|. .. ||.|.   
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---------RCDHNQWT---MTFCYTIEYMAPEMLKRAN

-GSEMSPSSDLWAFSVTLYLFLTGIYPFND---MSEYLVFRRIQDIL--YTFS-EDFPDENAKNLIERLLVKEQKSRLT-----SQEIKEHKFF
 ..  . . |.| . | .|  |||  ||      .   ...|||      |.   ..  ..||.|| ..| .. . ||.      .|||.|..|
QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase W04B5.5.AA Ciliate-E2-Unclassified 26-303 23 1.6e-49 169.94 In-house 1-352 (352) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-352/352
Sequence Identity: 23% (86 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEV-ALKICLKRLILKNKMVPYIHREKEALALISREEN------------------AHPGIVTLYATFQDSE
| . |  |.|.|..||....|    ... .. |.|.  |  | | | . . . |.   ...  . .                   || || .. .||| .
YKIIKQIGQGGFGKVYKCQHK----KQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ

SLYFVLEYAKYGDLCTLMQKQPD---------------SKFNVADSR-----YYAANLLSALEHIHKLG-IIHRDVKADNLLVKSDG---RIMLTDFGSS
 .|.|.||...|||   ..|..                 .|    ..     .|.| .|..||..|. . ||||| | .|.|....|   .| ..|||.|
NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS

KFLSDY--------QKIQENPVEEEQPTGRRSSFVGTAFFV----TPELLTGSEMSPS----SDLWAFSVTLYLFLTGIYPFNDMSEYL-----------
|.. .         ||.| .. .. .      .|.||  .      ||.| | . . |    .| |.. | || .|.| |||.| ...            
KKYQQNNNCDTNQQQKMQIWKQQMMW------TFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN

-----VFRRI-QDILYTFSEDF------PDENAKNLIE----RLLVKEQKSRLTSQEIKEHKFF
     ... | | ... .....       ...||..|.    ..|.| ...|.| ..|..| .|
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase W04B5.5.AA Ciliate-E2b 26-303 24 3e-48 144.79 In-house 1-272 (272) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-272/272
Sequence Identity: 24% (71 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQ
  . |. | | |  ||| ..    ....   |.|   |  |... |  .. .||. |     | . || |.... .|.|....||..|. . ..| ... 
MIYIKKLGFGQFGSVYLVWNT---KNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVL-----EKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIR

KQPDSKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFFVTPELLT----
 .    ..  ||. | | .. .||  |...||.||.|  | .| ..| . | |.| .|.... . .            |  . .|| ..  ||...    
EIGRLLLSTYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMT----------RTFTIIGTPHYMAPEIIQSLQP

-GSEMSPSSDLWAFSVTLYLFLTGIYPFNDMSE--YLVFRRIQDI--LYTFSEDFPDENA-KNLIERLLVKEQKSRL--TSQEIKEHKFF
 |   . ..|.|.. ..|| |. |  |.    .  | .   |        |   . |..| |.|....| |    ||  . .  | |..|
GGKGYTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase W04B5.5.AA CAMKL 26-303 23 4.2e-47 148.28 In-house 1-297 (297) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-297/297
Sequence Identity: 23% (76 aa)

YSVEKEVGEGSFSTVYLARR-KEPKNDENPEVALKICLKRLILK-------------NKMVPYIHREKEALALISREENAHPGIVTLYATFQDSES----
| ..|. |.|||..| ||.  . .    . .|| ||  |. | .              ...  | || . . ...     || |. || .....|     
YRIGKTLGKGSFGKVKLATHIRTT----GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLN--IGKHPNIIKLYEVIETPEHDIET

--LYFVLEYAKYGD--LCTLMQKQPD--SKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDG--RIMLTDFGSSKFLSDYQKIQENPVEEE
  .| |.||.  |.  |    .|...   ..   . | |   ..||....|..||.||| |..|.|. ..|   | ..||| | .  ..           
KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC----------I

QPTGR-RSSFVGTAFFVTPELLTG---SEMSPSSDLWAFSVTLYLFLTGIYPFN---------DMSEYLVFRRIQDILYTFSEDFPDENAKNLIERLLVK
 ..|.  . | |.  .  ||.. |   .   |  | |.  |.||  ..| .||.         |   ||  . ...  |     ...  ...|| ..|..
FGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQV

EQKSRLTSQEIKEHKFF
  . | | ..|..|...
NPEKRPTIHQIMNHPWM
Kinase W04B5.5.AA ULK 26-303 22 8.3e-46 157.9 In-house 1-329 (329) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-329/329
Sequence Identity: 22% (77 aa)

YSVEKEVGEGSFSTVYLAR--RKEPKNDENPEVALKICLKR-LILKNKMVP------YIHREKEALALIS---REENAHPGIVTLYATFQDSES--LYFV
|.. .. |.||| .|| .|  ... .   |  || |. .|  .. ||.. .       . .| . .  .    | .| || || ||  |..| .  .|..
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

LEYAKYGDLCTLMQKQPDSKFNVAD---------SRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSD------------GRIMLTDFGSSKFLSDY--
.||   ||| ....|.  .  ..            . .   .|... ..|| .||||| | .| |.. .            |.. ..||| .|....   
MEYCNGGDLEQYIKKNKKLPEDT-EEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNM

-QKIQENPV-EEEQPTGRRSSFVGTAFFVTPELLT----GSEMSPS-SDLWAFSVTLYLFLTGIYPFNDMSEYLVF-RRIQDILY----------TFSED
 |..    | |.         . ||  .  |..|     . . . . .|.| . . .|  |.| .||. .  .  . . ||. .           ..  .
EQQMMMTCVNEK--------RLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQ

FP--------DENAKNLIERLLVKEQKSRLTSQEIKEHKFF
||         .. |.|| |.|....| | . .|. .|..|
FPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase W04B5.5.AA Delta 26-303 32 7.5e-41 142.03 In-house 1-259 (259) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-259/259
Sequence Identity: 32% (91 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISREENAHPGIVTLYATFQDSESLYFVLEYAKYGDLCTLMQ
. ..| .| |||  | ||  |    ..|   |.|   |  .|.   |     |.  ||| .    .|| .  |. |||  | |.||.||   |||   .|
FHFHKVLGKGSFGKVMLAELK----GKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAW----EHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQ

KQPDSKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDYQKIQENPVEEEQPTGRRSSFVGTAFFVTPELLTGSEM
..   .|. . .|.||. ....|. .|| ||| ||.| ||.|.  || | . ||| .|         || . |    .. |.| ||  ...||.. |   
QC--HRFDEKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCK---------ENMYGE----KKASTFCGTPDYIAPEIIKGQKY

SPSSDLWAFSVTLYLFLTGIYPFNDMSEYLVFRRIQDILYTFSEDFPDENAKNLIERLLVKEQKSRLTS-----QEIKEHKFF
. | | |.| | .|  | |  ||    |  .|. |      .      | ||.....|.... . || .      .|..| ||
NHSVDWWSFGVLMYEMLIGQSPFHGEDEDELFWSICNDRPWYPRWITKE-AKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase W04B5.5.AA TyrKc 26-303 21 1.4e-13 -3.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-303
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKICLKRLILKNKMVPYIHREKEALALISRE-----EN--AHPGIVTLYATFQDS-------ESLYFV
 . .|. ||| | .||... |        .|| | . .                  .. . ||     .    || || ||.   ..       | |. |
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

LEYAKYGDLCTLMQKQPDSKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFGSSKFLSDY-QKIQENPVEEEQPTGR---RSS
.||...|||    .|  .  ....|  ...    .  |..|. ..||||  | | ||......  .||| |... |. |.     ....  . .    . 
MEYMPHGDLKDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----ESKDYYRKKEHKGGK

FVGTAFFVTPELLTGSEMSPSSDLWAFSVTLY-LFLTGIYPFND-----MSEYLVFRRIQDI-LYTFSED--------FPDENAKNLIERLLVKEQKSRL
..       || .  .. .. || |.| |... .|  |  |  .     || . |......       ..         |||  . ....    . ..| 
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRP

TSQEIKEHKFF
| .||  |..|
TFSEI--HECF
Kinase W04B5.5.AA Pkinase_Tyr 92-180 29 7.4e-09 30.62 Pfam 63-156 (270) Show / Hide 
Range on Protein: 92-180
Range on HMM: 63-156/270
Sequence Identity: 29% (28 aa)

HPGIVTLYATFQ-DSES--LYFVLEYAKYGDLCTLMQKQ--PDSKFNVADSRYYAANLLSALEHIHKLGIIHRDVKADNLLVKSDGRIMLTDFG
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HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase W04B5.5.AA Pkinase_Tyr 26-61 30 0.008772 10.05 Pfam 1-36 (270) Show / Hide 
Range on Protein: 26-61
Range on HMM: 1-36/270
Sequence Identity: 30% (11 aa)

YSVEKEVGEGSFSTVYLARRKEPKNDENPEVALKIC
 .  |. |||.| .||... |  . ... .|| |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML