Gene W03G9.5 (Nematode worm)
W03G9.5
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| W03G9.5.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 269 | Kinase domain by global Sugen HMM | Fasta, JSON |
| W03G9.5.AA | Protein | Genbank | 488 | None | Fasta, JSON |
Protein domains of W03G9.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | W03G9.5.AA | TTBKL | 18-285 | 37 | 1.8e-140 | 472.93 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 18-285 Range on HMM: 1-288/288 Sequence Identity: 37% (109 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTV-FDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNK-FS ... ...||||.|..|.| ..|... ..|.|.| .. ..| .. ||... .||....|.|. .... |. ..|.|.||||.||.|...|...|..| || WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS TFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALG--TPKQRLVHVLDFGISRQYLVKDGEN------GGLRIRKPRR---IVPFRGTLRYCSVAA ......||| |...|..||.||.||||||.|...|. . ....|.|...|||..|||..||||. .....|.||. .|||||.||||... DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM QERKEQGRHDDLWSLFYMIVEFVKGSLPWTGIM-EEEKVIVMKEDVTELFNG-------LESECAMFAQHLSVLRYQTNPDYALLRDLL ..||||||||||||..|||.|...| ||||... ..| . ..|. .|.... ..||...|..||. |||. ||| .. .. HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | W03G9.5.AA | CK1 | 18-281 | 30 | 4.8e-106 | 358.61 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-339/339 Sequence Identity: 30% (102 aa) YLAFRKLGEGGCG-VIYEV-----AMVKCPG----RRFACKAETTV-FDEDPTLPMEHKIISKLN------------------EKNSIHCVELIDKGQSD . .|.||||.| ||.| .|... ..|.|.| . .|.| .|.... ||. ... |.. ....| | WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED NYQ-FIVMTLLGPSLDAIRA--TLPTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALG-----------TPKQRLVHVLDFGISR-QYL .| ..|||||||.|. .|. .....||| ..| .|| |......||.||.|||.||.||..|. . .. | |...|||..| .|. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR VKDGEN-------GGLRIRKPRR---IVPFRG-TLRYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGS--LPWTGIMEEEK-----VIVMKEDVTEL--F |||.| . ..| ||. ..||| |.||||......|||||.|||||.|||..|..||. |||... .|.| |..||.. . . DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM NG------------LESECAMFAQHLSVLRYQTNPDYALL . . .| ....... |.|.. |||. . STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | W03G9.5.AA | TTBK | 18-281 | 40 | 7.8e-73 | 248.28 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 18-281
Range on HMM: 1-257/257
Sequence Identity: 40% (107 aa)
YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF
.| | || | ||| . . | | | . | || . || .. | | | |.. ..||.|.| .| | | .||
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVE-SAQQPKQVLKMEVAVLKKLQGCD--HVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLS
STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLW
.|| .|.| |.||..||..|| |||.|| |||.| . . | . |||| |||. || .| || |||| || |. | .| |||||||
TTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPS-TCRKCYMLDFGLARQYTNACGE-----VRPPREVAGFRGTVRYASINAHRNREMGRHDDLW
SLFYMIVEFVKGSLPWTGIMEEEKVIVMKE--DVTELFNGLESECAMFAQHLSVLRYQTNPDYALL
||||| ||||.| ||| | ..| ||| | | . . .| .| .|...| |.. |||.|.
SLFYMLVEFVQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
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| Kinase | W03G9.5.AA | Worm6 | 18-281 | 32 | 6.8e-72 | 245.15 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-279/279 Sequence Identity: 32% (91 aa) YLAFRKLGEGGCGVIYEVAMVKCPGR-RFACKAETT-VFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDN--YQFIVMTLLGPSLDAIRATLPTNK . .|.||||.| .|.| . .||.|.| . . |.||. . ... ... | ....|.|. || . .|||||.|..| .|...|..| WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK FSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGA---LGTPKQRLVHVLDFGISR--QYLVKDGENGGLRIRKPR-RIVPFRGTLRYCSVAAQER || .| .|| |..| . | .||.||||||.||.|| ... . ||||..| .|. |..| .|.|| ..||||.||...|. . FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNE-----LRTPRWTACGFRGTVRYAPLACHKG KEQGRHDDLWSLFYMIVEFVKGSLPWTGIMEEEKVIVMKEDV---------TELFNGLES-ECAMFAQHLSVLRYQTNPDYALL .||.| ||. | |||.||...| ||| .. .. | . |. ...|.. | . . ..|.. |||. . QEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | W03G9.5.AA | CK1-Unique | 18-233 | 28 | 3e-35 | 119.65 | In-house | 1-232 (337) | Show / Hide |
Range on Protein: 18-233 Range on HMM: 1-232/337 Sequence Identity: 28% (67 aa) YLAFRKLGEGGCGVIYEVAMVKCP-----GRRFACKAETTVFDED----PTLPMEHKIISKLN--EKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIR . . ..| || | ..| |. . ... | | . . | |.|. .| . | |..| .|.. . .||||..|||.. .. WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC ATLPTNKFSTFS------TLV-MGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQ--YLVKDGENGGLRIRKPRRIVPFRGTL . .| | . ... .| | |. | | || ||. ||.|. .| .|. .||.||.| ... .. ||.|| |.||||.. MMMKNFQF-TLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQ-----IRQPRPITPFRGCK RYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGS--LPW .||. . . .|.|| ||. |.|||.. | . | | DYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSW |
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| Kinase | W03G9.5.AA | CK1-D | 18-281 | 31 | 1.3e-31 | 108.78 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-261/261 Sequence Identity: 31% (86 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF | ||.| | | || . .. . | | | .. . | | .| |. .. | . . || .| .|| ||||||. . ||| YRIGRKIGSGSFGDIYHGTNIQT-NEEVAIKLE-CIKTKHPQLHIESKFYKMMQGGIGIPEIRWC--GQEGDYNVMVMDLLGPSLEDL-FNYCHRKFSLK STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGE-NGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDL |... | . |. || |.|||.|| || .| || . .|...|||....| .| . . | . . || || |. || | ||| TVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMG-LGK-RGNMVYIIDFGLAKRY--RDARTHQHIPYRENKNLT---GTARYASINTHQGIEQSRRDDL WSLFYMIVEFVKGSLPWTGIMEEEK-----VIV---MKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALL || |... | .||||| |. | |. |. . .| .|. || . . . |... |||. | ESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | W03G9.5.AA | Dual | 77-223 | 36 | 1.9e-31 | 102.89 | In-house | 71-213 (282) | Show / Hide |
Range on Protein: 77-223 Range on HMM: 71-213/282 Sequence Identity: 36% (55 aa) HCVELIDKG--QSDNYQFIVMTLLGPSLDAIRATLPTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLV . .|..| | . | ..|| . ||||. || . .|. . .|| |..|. | ||..||..|||||..| || . | .||.| | |. CFIEFVDYGKCEQDKCKYWVMSPYGPSLQEIRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCG-LGM-DETTVYMQDFRIVRKYI- KDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLWSLFYMI | ||. |. .| | . |..|| . | . |.||| ||| . ||. -DPENKKHRT--ARKKVKMYGCGRYACRACMMQKDQGRKDDLECWIYMV |
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| Kinase | W03G9.5.AA | CK1-A | 18-281 | 29 | 3.4e-31 | 107.4 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 18-281 Range on HMM: 1-261/261 Sequence Identity: 29% (81 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGPSLDAIRATLPTNKFSTF | ||.| | | || ... | | | | | | | |. |. | .. |. .| .|| ||||||. . . . .|. YRLVRKIGSGSFGDIY-LGINITNGEEVAIKMESNKA-RHPQLIYEAKVYRILQGCVGIPHMRWY--GCEKDYNVMVMDLLGPSLEDL-FNFCKRRFTMK STLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAAQERKEQGRHDDLW |.. | . | .| .|.|||.|| || .| .| .| ...|||....| . . . |. . .. || || |. |. || | ||. TVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMG-IGRHCNKL-FLIDFGLAKKYRDSRTRQ-HIPYREDKNLT---GTARYASINAHLGIEQSRRDDME SLFYMIVEFVKGSLPWTGIMEE------EKVI--VMKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALL |. |... | .|.||| |. ||. | . .| | .| .|. .. ||.. .||| | SMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | W03G9.5.AA | CK1 | 18-236 | 31 | 1.4e-29 | 99.06 | In-house | 1-219 (271) | Show / Hide |
Range on Protein: 18-236 Range on HMM: 1-219/271 Sequence Identity: 31% (74 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRR--FACKAETTVFDEDPTLPMEHKIISKLNE---KN-SIHCVELIDKGQS--DNYQFIVMTLLGPSLDAIRATL | ||.|.| |.||.. . | . |.| | | |. | || |. | ... .. || .| ..||.||||||. . YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNF PTNKFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFR------GTLRYCSVA ||| .| . | .. | .| .|.|||.|| || .| . .. |.. |||.. .|. | .. .|.| || || |. CNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR-YGKHCHQVYIIDFGLAKRYR----------DDKTHQHIPYRENKNLTGTARYASIN AQERKEQGRHDDLWSLFYMIVEFVKGSLPWTGI . .||.| ||. || |... | .||||| |. THLGIEQSRRDDMESLGYVLMYFLRGSLPWQGL |
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| Kinase | W03G9.5.AA | CK1-Unclassified | 18-178 | 31 | 1.3e-22 | 63.53 | In-house | 1-166 (244) | Show / Hide |
Range on Protein: 18-178 Range on HMM: 1-166/244 Sequence Identity: 31% (54 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSI-----HCVELIDKGQSDN--YQFIVMTLLGPSLDAIRATLP | .|.| | | ||.. .. . .|.| | . |.|. | || |. .. . .. || .. |...||.||||||. . YRVIEKIGQGSFGEIYKCINMQTN-EEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMC- TN-KFSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYL-V-KDGE | ||| .| . | .. | .| .|.||| || || .| || .. |. |||.| |. |.|. -NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGK-NHHQVYIIDFGLSKRYIDMDKTGK |
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| Kinase | W03G9.5.AA | S_TKc | 18-303 | 17 | 1.9e-13 | 20.17 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 18-303 Range on HMM: 1-231/231 Sequence Identity: 17% (54 aa) YLAFRKLGEGGCGVIYEVAMVKCPGRRFACKAETTVFDEDPTLPMEHKIISKLNEKNSIHCVELIDKGQSDNYQFIVMTLLGP---SLDAIRATLPTNK- | ||.|.|. |. | . .| ||..|.| .. | .| .| . . | |.| |. .. ..|| ... .| . .... YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FSTFSTLVMGIQALDSIKEIHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCS--VAAQERK |. . . | .. .. .|. |..|||.||.| . . . |||..||. | ||. |.. | RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------------------TTFCGTPWYMAPEVL----- EQGR-HDDLWSLFYMIVEFVKGSLPWTGIMEEEKVIVMKEDVTELFNGLESECAMFAQHLSVLRYQTNPDYALLRDLLM-NIFVRRNFNAQMK------- |. | ||. .. |.. | |. |.. ... . . ..| .| . | .. GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC VDWE | HPWF |
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| Kinase | W03G9.5.AA | CK1-Unclassified | 195-241 | 51 | 1e-10 | 27.89 | In-house | 178-224 (244) | Show / Hide |
Range on Protein: 195-241 Range on HMM: 178-224/244 Sequence Identity: 51% (24 aa) GTLRYCSVAAQERKEQGRHDDLWSLFYMIVEFVKGSLPWTGIMEEEK || || |. | .||.| ||| || | .. | |||||| .| ..| GTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNK |
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| Kinase | W03G9.5.AA | Pkinase | 133-246 | 23 | 4.5e-08 | 29.64 | Pfam | 124-230 (293) | Show / Hide |
Range on Protein: 133-246 Range on HMM: 124-230/293 Sequence Identity: 23% (28 aa) IHDIGFVHRDVKPANFAIGALGTPKQRLVHVLDFGISRQYLVKDGENGGLRIRKPRRIVPFRGTLRYCSVAA-QERKEQGRHDDLWSLFYMIVEFVKGSL .|. |..|||.||.|. | |... |.. |||...|. . . . | ||..|.. ..... |. | ||. .. |.. | . CHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRP PWTGI-----MEEEKVIVMK |. | ... ..|... PFPGHCWHDNHDQMQMICRI |
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| Kinase | W03G9.5.AA | Dual | 270-285 | 37 | 0.005838 | 5.64 | In-house | 267-282 (282) | Show / Hide |
Range on Protein: 270-285 Range on HMM: 267-282/282 Sequence Identity: 37% (6 aa) LRYQTNPDYALLRDLL . |.. |||. .| | YQYDSTPDYDYFRNCL |
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| Kinase | W03G9.5.AA | CK1 | 249-279 | 31 | 0.010325 | 5.4 | In-house | 240-271 (271) | Show / Hide |
Range on Protein: 249-279 Range on HMM: 240-271/271 Sequence Identity: 31% (10 aa) VTELFNG-LESECAMFAQHLSVLRYQTNPDYA | .|..| . .| ||. .. |... |||. VEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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