Gene W02B3.2 (Nematode worm)
W02B3.2
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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W02B3.2.AA | Protein | Genbank | 727 | None | Fasta, JSON |
W02B3.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 265 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of W02B3.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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RGS | W02B3.2.AA | RGS | 54-175 | 26 | 1.1e-34 | 122.41 | SMART | 1-121 (121) | Show / Hide |
Range on Protein: 54-175 Range on HMM: 1-121/121 Sequence Identity: 26% (33 aa) KFDKIF-NQKLGFLLLKDYAENVSESPCPQIKFYEAIKEYEKMETPDERLTKAREIYDHHIMVEMLA-HAHNYSKESLQHVQYHLLKQNVPPDLFHRYVL |.... |.. | .. ... .. ..... ..|..|..|..|||. .|| ||||||| .|... . |..|..... ...| .| . ..||.| .. SFHHLCDNDPIGRRYFREFLKQEFCEYKENLEFWLACEEFKKMED-EERRQKAREIYDKYISPNAPCEHCVNIDHHTREQCQQCLCN--PHPDCFDEAQR EICDQLRGDIFQRFLESDKFTRFC .... ...| ..|||.||...|.. HVYQLMEKDSYPRFLRSDYYKRYL |
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RGS | W02B3.2.AA | RGS | 54-174 | 27 | 1.4e-33 | 112.76 | Pfam | 1-124 (124) | Show / Hide |
Range on Protein: 54-174 Range on HMM: 1-124/124 Sequence Identity: 27% (34 aa) KFDKIFNQKL-GFLLLKDYAENVSESPCPQIKFYEAIKEYEKM--ETPDERLTK-AREIYDHHIMVEMLAHAHNYSKESLQHVQYHLLKQNVPPDLFHRY |....| . |..| ... |. .. . |.|..|.....|| ........| |||||. .|. . . || .... .|.| .| .... ||.| .. SFHHLCNDQPIGRRLFRQFLESEFCEY-ENIEFWLACEDFKKMFSDSDEKMHQKDAREIYNKYIAPDSPCECHNIDHDTREHCQDNLEQAQPTPDCFDEA VLEICDQLRGDIFQRFLESDKFTRF .|.. ...| ..|||.||.. || QRHIYTLMEKDSYPRFLKSDYYQRF |
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Kinase | W02B3.2.AA | BARK | 191-455 | 88 | 1.5e-227 | 762.23 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-264/264 Sequence Identity: 88% (235 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVF ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||..|||||||||||||||||||||||||| FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVF TEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHS .||||.|||.|.|||||||||||||||||||||||||||||||.||||||||.||||||||||||||||||||.||.|||||||||||||||||||.||| SEQEMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDENGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTAYDSSADWFSLGCMLYKLLRGHS PFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF ||||||.|||.|||.||||...||| ...||..||||||||.|||..||||.|.|..|||||||| PFRQHKTKDKHEIDRMTLTMNVELP-DSFSKEMRDLLEGLLQRDVSKRLGCMGRGAQEVKEHPFF |
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Kinase | W02B3.2.AA | GRK | 191-455 | 56 | 1.8e-212 | 676.49 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-272/272 Sequence Identity: 56% (154 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGV- |...|..|.||||||..|....||||||.|||||||||...|||.||||...|..|... ||||||||.||....|.||.....|||||||||....|. FRQYRVLGKGGFGEVCACQVRATGKMYACKCLDKKRIKKRKGETMALNEKQILEKVHSR-DCPFIVCMAYAYETKDALCLVMTIMNGGDLHYHIYNMGNN ---FTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKK--PHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYK |.|..|.|||.|...||||||.|..|||||||.|||||..||||.|||||||...... .|..|||||||||||| ...|||.|.||.|||||.|. EPGFDEERMRFYAAEICCGLEHMHRRRIVYRDLKPENILLDDHGHVRISDLGLACEIPEGQPMIHGRVGTHGYMAPEVLQNERAYDFSPDWWSLGCMIYE LLKGHSPFRQHKSKDKN-EIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGK--GPTEVKEHPFF ...||||||||| |.|. |.|..........| . .|....|..|.||..|. .||||||. |..|||||||| MIEGHSPFRQHKEKVKREEVDRRVKEDPVKYP-DKFSEEAKDICEMLLQKDPEQRLGCRGGTCGAQEVKEHPFF |
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Kinase | W02B3.2.AA | AGC | 191-455 | 26 | 6.7e-146 | 380.05 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-395/395 Sequence Identity: 26% (108 aa) FSVHRIIGRGGFGEVYGCRKA------DTGKMYAMKCLDKKR-IKMKQ--GETLALNE------------RIMLSLVS--------TGQDCPFIVC-MTY | ....||.|.||.|| .|| ||||.||||.|.||. |..|. . ...| | .|.... . ..|||| . | FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKS--HHPFIVKILHY AFQSPDK--LCFILDLMN---------GG-DLHYHLS---QHGVFTEQEMIFYASE-------VILGLEHMHN-RFVVYRD-LKPANILLDENGHVRVSD .||..|. |.|....|. || .|..|| . |.|.|.. |||.| ..|.||..|. . ...|| ||| ||||||.||.. .| SFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTD LGLACDYSK----------------------------------------------------KKPHASVG--THGYMAPEVLAKGVAYDSSADWFS--LGC ||.. . .. . .| |. |||||.| |. ..|| | ||| FGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGC MLYKLLKGHSPFRQH-------KSKDKNEIDKMTL------TQDIELPN---------EGLSKDCRDLLEGLLKRDVPDRLGCRGK-----GPTEVKEHP ..| .| |..||. . . ....|. . . ......|. . .|....||...||..| .||||.|. | |.|.|| LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP FF .| WF |
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Kinase | W02B3.2.AA | GRK | 191-455 | 45 | 2.1e-101 | 343.21 | In-house | 1-265 (265) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-265/265 Sequence Identity: 45% (124 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHG-- | |. | |||||| | |||||| | |.||||| ..||..|||| | |. .|.| . ||. . | || .. .|||||| .|. | FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEQMALNEKQILEKVH----SRFVVSLAYAYETKDALCLVMTIMNGGDLKFHIYNMGEN -VFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKP-HASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLL | |. |||| |...|||| | . .||||.|| |||||. ||.|.|||||| .. ||| |||||||. . |. | ||..||| .| PGFDEERAIFYAAEICCGLEHLHRERIVYRDMKPENILLDDHGHIRISDLGLAVEIPEGQMIRGRVGTVGYMAPEVVKNER-YTFSPDWWGLGCLIYEMI KGHSPFRQHKSK-DKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF |.||||| | | . |.|. .. .. . . | |.. .|. . ||. | |||||..| ||..|||| EGRSPFRQRKEKVKREEVDRRVKEDPEKYSHEKFSEEAKDICRMLLHKDPEQRLGCREEGCDEVRQHPFF |
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Kinase | W02B3.2.AA | Pkinase | 191-455 | 28 | 6.2e-95 | 326.5 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-293/293 Sequence Identity: 28% (88 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLAL--NERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGG----DLHYHL . ..|.||.|.||.|| |.. .|||..|.|...|...|... .|... .||..| . .|.|| . ..|...|..........|| ||. .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI S--QHGVF--TEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHV----RVSDLGLAC---DYSKKKPHASVGTHGYMAPEVLAKGVAYDSSA | .||.| .|.| .||. ... |||..|.. ...|||||.|||.|.|||. ...| |||. .. .. .|| .||||||. .| |.... STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV DWFSLGCMLYKLLKGHSPFRQH----KSKDKNEIDKMTLTQDIELPNE--------------------GLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEV |..|.||.|| .| |. ||..| . |.... .... ... . . .|..|.|.....|..| .|.. .... DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQI KEHPFF ..||.| LQHPWF |
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Kinase | W02B3.2.AA | RSK | 194-455 | 35 | 1.2e-88 | 300.84 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 194-455 Range on HMM: 1-278/278 Sequence Identity: 35% (100 aa) HRIIGRGGFGEVYGCRKA---DTGKMYAMKCLDKKRIKMKQG-ETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGV .. |.||.|.|. ||| |||. |||| |.|. |. .| .. || |... | .|||| |||| ..|| |.....||.| .||.... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERC---QQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKH ---FTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDE---NGHVRVSDLGLACD--YS-KKKPHASVGTHGYMAPEVLA---KGVAYDSSADWFS |.| | ||..|..| .||.| . ...||||| |||.|. .||....| |... . ... . ..|. |||||.|. .....| ..||.| FGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS LGCMLYKLLKGHSPFRQHKSK-DKNEIDKMTLTQD--IELP-NEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF ||. .| .| |..||.. . ...|| | .. . ..| .. ||....||. ..|.|| .|||| .. |.|.||.| LGVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | W02B3.2.AA | Akt | 191-455 | 37 | 1.3e-85 | 273.63 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-264/264 Sequence Identity: 37% (102 aa) FSVHRIIGRGGFGEVYGCRKADTGKMY-AMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGV | . ...|.| || |. ..| ||.|.| ||| | |..| .| .. || .| . .|||| . |.||..|||.|..| .|||.| |||.. .. FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN----HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR FTEQEMIFYASEVILGLEHMHNRFVVYRD-LKPANILLDENGHVRVSDLGLAC-D-YSK-KKPHASVGTHGYMAPEVLAKGVAYDSSADWFS-LGCMLYK |.|.. ||..|.||..|| |.. ..||| ||| |||.|..||... | ||. . . | || |.|||.| . . .. ..|| . ||| .| FSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYE LLKGHSPFRQHKSKDKNEIDKMTLTQDIELPN-EGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF .. | || .. .|. . | ..|... |. . .|..|.||..|||..| ||| .. |.|.||.| MMCGRPPF--YN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF |
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Kinase | W02B3.2.AA | S_TKc | 191-455 | 29 | 2.9e-85 | 290.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-231/231 Sequence Identity: 29% (82 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNG--GDLHYHLSQHG . ..|.||.|.||.|| ||. .||. .|.|... ...|. .|. ..|.|| . ..||. |.|........| |||. .. ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG V------FTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAKGVAYDS-SADWFSLGCM |.| . ||. .....||..|.. ...|||||.|||||| |. ..| |||. . . .|| ||||||| |. ..|| |.||. RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI LYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGKGP--TEVKEHPFF || .| | ||. . ... . | |....|.....|..| .|... ..| ||.| LYEMLCGYPPFP----------QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | W02B3.2.AA | SGK | 191-455 | 36 | 1.9e-82 | 254.32 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-283/283 Sequence Identity: 36% (106 aa) FSVHRIIGRGGFGEVYGCRKADT------------------GKMYAMKCLDKKRIK-------MKQGETLALNER-IMLSLVSTGQDCPFIVCMTYAFQS | .|| |.||.|| .. |. .|.|||| | |. | | . . . || |.... |||| |||| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMK----HPFIVNLHYAFQT PDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHAS--VGTHGYMAPEV ..|| | .| .|||.. ||| . | | . |||.|... ||. | ..|||||| ||||| ||.. | ||. |.. . || |.|||| KWKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEV LAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF |.| .| . ||..||| || .. | || |..|.. . |.. .| . | |..||..|||..|. .||| . .. |.|.|||| LRK-QPHDRTVDWWCLGCVLYEMMYGLPPFY---SRNKQQMYDNIINQPLQIP-PQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF |
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Kinase | W02B3.2.AA | AktR | 191-455 | 34 | 9.2e-80 | 271.29 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-268/268 Sequence Identity: 34% (96 aa) FSVHRIIGRGGFGEVYGCRKA-DTGKMYAMKCLDKKRIKMKQGETLALNERIMLS-LVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHG | |....|.|.||.|| ..| |..|.|||| ..|| |. .. . ...|| . .. . |||| . |.||. .|| ||.. . ||.| .||.. . FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCC----NHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKK VFTEQEMIFYASEVILGLEHMHNR-FVVYRDLKPANILLDENGHVRVSDLGLAC---DYSK-KKPHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLY |.|.. ||.....|.||. |.. ..|||||| ||||||.|||. .| ||. . .. | . .||. |||||.. | . .. |.|| ..|. .| KFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY KLLKGHSPFRQHKSKDKNEIDKMTLTQD-IELPN-EGLSKDCRDLLE-GLLKRDVPDRLGCRGKGPTEVKEHPFF .. |. || ... .|.. .. .... .. | . .|. |.||.. .||... ||| .|..|.|.||.| EMVTGCPPFYHKN---QNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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Kinase | W02B3.2.AA | RSK | 191-455 | 35 | 9.5e-71 | 241.36 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 191-455 Range on HMM: 1-271/271 Sequence Identity: 35% (100 aa) FSVHRIIGRGGFGEVYGCRKA---DTGKMYAMKCLDKKRIKMK-QGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQ . .|. ||.| |..|| |.| ||.. |||| ..|. .. | . . .|||.|. . . |||| |.||. |. |.|.| |||| .|. YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR--VCWEEERIILRYG----HHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLK HGVFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDEN----GHVRVSDLGLACDYSKKKPHASVG-------THGYMAPEVLAKGVAYDSSADW ..|.|.| ||..|. | .|. | .|.|||||.|||.|. ||... |.|.| |. . | | ||||||| . .| ..|| QKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFA-----KQLRDENGMLMTFCYTANYMAPEVLKR-QGHDQACDW FSLGCMLYKLLKGHSPFRQHKSKD-KNEIDKMTLTQ-DIELPN-EGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFF .|.| .| | |. || .. .| | . | . .. .| . .|. . ||| ..|.|| |||. | ..|.||.| WSFGVLMYEMLTGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF |
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Kinase | W02B3.2.AA | RSK-Unclassified | 191-348 | 39 | 1.5e-52 | 163.15 | In-house | 1-157 (283) | Show / Hide |
Range on Protein: 191-348 Range on HMM: 1-157/283 Sequence Identity: 39% (63 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLS--QHG | .|| ||.| ||.|| || || ..|||| | |... .. .. |. ... . |||| . ..||. |.| ... |||. || FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATT----NHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEK VFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDY-SKKKP |.| . ||||||.. ||..| | ..|||||| ||.|. |||. .| .| . ||| CFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKP |
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Kinase | W02B3.2.AA | RSK-Unclassified | 352-455 | 33 | 6.9e-28 | 84.26 | In-house | 183-283 (283) | Show / Hide |
Range on Protein: 352-455 Range on HMM: 183-283/283 Sequence Identity: 33% (36 aa) VGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELP-NEGLSKDCRDLLEGLLKRDVPDRLGCRGKG-PTEV .|| |.|||.. .. ||. || ..| .| | |. . |||. . ..... .| .. .|..||||. ||.| |||| ..| .. CGTEEYLAPEMI-RRCGHTKAVDWWTLGIVMYEMLFGCPPY---YGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGC-KMGDADDI KEHPFF | |||| KRHPFF |
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Kinase | W02B3.2.AA | S_TK_X | 456-535 | 23 | 1.9e-16 | 61.92 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 456-535 Range on HMM: 1-79/79 Sequence Identity: 23% (21 aa) KDVDWQTVYL--RRMTPPLIPPRGEVNAADAFDIGNFDDDEVKGVKLQDGDSDLYKNFNIVISER-WQNEIAETI-----FEVVNQDA ...||...| ....|| .|. ||.| ...|..|||... ... ..... ..|.. |||| .|| |. . .. RGIDWDKLYNQQKEIEPPFKPKIKEVYA-SPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF |
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Kinase | W02B3.2.AA | TyrKc | 191-439 | 18 | 6.7e-11 | -46.4 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 191-439 Range on HMM: 1-280/280 Sequence Identity: 18% (55 aa) FSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNE-RIMLSLVSTGQDCPFIVCMTYAFQSP-------DKLCFILDLMNGGDLHY . ...|.| ||||| .. . | |.| . . ..| ||| .| | . | ||.. . .. . |. .. .| .|||. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKL---GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD HLSQHGV-FTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKK------KPHASV----GTHG-----YMAPEVLAKG .| |. .. .... .. . | |. | . .. ||| |.|..||..|..|| ||. | . | .. |... ||||.. .| YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG VAYDSSADWFSLGCMLYKLL-KGHSPFRQ---HKSKDKNEIDKMTLTQDIELPNEG--------LSKDCRDLLEGLLKR---------DVPDRL . . . | .| | ... .. | .| . .. |. . . . . . ... .. . .. .. ... K-FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | W02B3.2.AA | Pkinase_Tyr | 267-340 | 26 | 3.1e-05 | 18.37 | Pfam | 81-158 (270) | Show / Hide |
Range on Protein: 267-340 Range on HMM: 81-158/270 Sequence Identity: 26% (21 aa) KLCFILDLMNGGDLHYHLSQH----GVFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLA ... .. .| .|||. .| .| . .| .... .. .. |.|. ... . ||| |.|..||..|...| ||| QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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Kinase | W02B3.2.AA | Pkinase_Tyr | 191-206 | 43 | 0.899233 | 3.24 | Pfam | 1-16 (270) | Show / Hide |
Range on Protein: 191-206 Range on HMM: 1-16/270 Sequence Identity: 43% (7 aa) FSVHRIIGRGGFGEVY . . .|.| ||||| ITFGKKLGEGAFGEVY |
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PH | W02B3.2.AA | PH | 559-680 | 12 | 0.00097 | 19.67 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 559-680 Range on HMM: 1-82/82 Sequence Identity: 12% (15 aa) VIVHGYIKKLGGPFTSAWQTKYGKLYPSRLELYPESLTAKPELVFMDQIEDVCAEMQTIKGETAIIVKLRDGFKEPKICLTNSVSENVLKYKTEKKNCRS || .|...|.. |. .. |....| .| .. .. . .... . | .. .. |. .. ..| VIKEGWLYKKS---K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P-------CFEIHH-DR---------------TYYFQCE------ VYLDEISLKEWHTSLRTAHKVS .| ...|| .... | . . ---SEEEMQEWMQAIQKAIHNN |