Gene W01B6.2 (Nematode worm)
W01B6.2
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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W01B6.2.AA | Protein | Genbank | 366 | None | Fasta, JSON |
W01B6.2.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 273 | Kinase domain by global Sugen HMM | Fasta, JSON |
Protein domains of W01B6.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | W01B6.2.AA | TTBKL | 24-298 | 46 | 8.49999999999e-155 | 520.55 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 24-298 Range on HMM: 1-288/288 Sequence Identity: 46% (136 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGF |.| | |.|||||.|| . ...|.|..||.|.|.|..|||.... . . . ....... ||.| .|.. ||| |..|||||.|.||..|.... . . .| WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKK-RF SRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETD-SERARIVHILDFGLARPFAVFHA------RENKWIARRARG---TAEFRGTLRYTSPN |.|||||||||||||||..||.|||||||||.|. .|.... .||.|.|...|||.|| .|.... .||||..||.| .|.||||.||.||| SDGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPN VHLRKEQGRVDDVWSLLYVIIELNGGKALPWQTDSQRERVEQMKLNLPAKVVMSN------MPACMDKVMPHLASLDYYQRPDYHMIFKCF .|.||||||.|| ||..|.||||..| |||. ......|.||.|. ...... .| ...|.|.|| ||.||.||||.||..|| MHDRKEQGRHDDLWSWMYMIIELHCG--LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | W01B6.2.AA | CK1 | 24-294 | 33 | 2.1e-115 | 389.71 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 1-339/339 Sequence Identity: 33% (115 aa) WKIGKTIDEGGFG-KVYIA-----TSISDPK----KVAALKAESNEIEGGSAIKLEAMILNKLNANG------------------PVPHIPVVHLCAKRK ||..| |.||||| .| . ......| . .|.|.|... .|.. ..|. .. |. .| ..||..... . ... WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED LYC-YMVMTLLGRNLRKLKSTNLVVNNGFSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETD----------SERARIVHILDFGLAR-PFA |. ||||||||.|| .|. .| |. || .|| .|.||.|.||.|.||.||||||.||.||..| ... ....|.|...|||.|| .. DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR VFHA-------RENKWIARRARG---TAEFRG-TLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKA-LPWQTDSQRER-----VEQMKLNLPAKVVM .. |...|. |..| .. ||| |.||.|.|.||.|||||.||.||..|..||.. |.. |||| ... .. ||.|| . .. | DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM SN------------MPACMDKVMPHLASLDYYQRPDYHMI |. .| .. |.|... ||.|| ||||.|| STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | W01B6.2.AA | Worm6 | 24-294 | 32 | 8.5e-61 | 208.29 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 1-279/279 Sequence Identity: 32% (94 aa) WKIGKTIDEGGFGKVYIATSISDPKK-VAALKAESN-EIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKL--YCYMVMTLLGRNLRKLKSTNLVV ||..| | ||||| || .. || || |.|.|. | . . |.|.|.|.... . .| . . ..| . . |.||||.|.||. |. . WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHK-CRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRP-- NNGFSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNE--TDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHLR .. || || .|.|||| |. .| .|||||||||.|| | ... ... .||||..| ... ..|. . .|. ...||||.|| . . | . DRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCR-RKKYCNKGNELRTPRW-TACGFRGTVRYAPLACHKG KEQGRVDDVWSLLYVIIELNGGKALPWQTDSQRERVEQMKLN----LP---AKVVMSNMPA-CMDKVMPHLASLDYYQRPDYHMI .||.| ||. | .|...|. | |||. . . .||. | . .. . . |. ....| . ...|. |||| | QEQCRKDDCESWFYMMVEMIVG-CLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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Kinase | W01B6.2.AA | TTBK | 24-294 | 35 | 1.5e-58 | 200.81 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 1-257/257 Sequence Identity: 35% (96 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGF ||. | | |||| .| |. . . |.| || . |.| .| || .|. | . ||||.|.|.|| | . | WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQP-KQVLKMEVAVLKKLQGC---DHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQP--RGCF SRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHLRKEQGRV | .| |.|.| | ... .|. || |||.|| || .| ... |.. .||||||| . . | .| | |||| || | | |. .| || SLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRN--PSTCRKCYMLDFGLARQYTNACGE-----VRPPREVAGFRGTVRYASINAHRNREMGRH DDVWSLLYVIIELNGGKALPWQTDSQRERVEQMKLNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMI || ||| |. .| | ||| .. | .|| .. . ..| . | |..||.| |||| .| DDLWSLFYMLVEFVQGQ-LPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | W01B6.2.AA | CK1-D | 24-294 | 32 | 2.4e-33 | 114.95 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 1-261/261 Sequence Identity: 32% (90 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGF ..||. | | || .| | |. | |.| |. . ...|. . . .| . || .. | . | ||| ||| | | | | YRIGRKIGSGSFGDIYHGTNIQTNEEV-AIKLECIKTK-HPQLHIESKFYKMM--QGGI-GIPEIRWCGQEGDYNVMVMDLLGPSLEDL--FNYCHRK-F SRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHLRKEQGRV | | .. | . ..|.| . |||||.|| |||.| | .|.|.|||||. . || . |. | . || || | | |. || | SLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGL---GKRGNMVYIIDFGLAKRYR--DARTHQHIPYREN--KNLTGTARYASINTHQGIEQSRR DDVWSLLYVIIELNGGKALPWQ-----TDSQR-ERVEQMKLNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMI ||. || ||.. | | .|||| | |. ||. . |.. . ... . .| . | . .| . ..||| . DDLESLGYVLMYFNRG-SLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | W01B6.2.AA | CK1-A | 24-294 | 31 | 4.3e-30 | 103.44 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 24-294 Range on HMM: 1-261/261 Sequence Identity: 31% (88 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGF ... . | | || .|.. .| . . | |.| |||. . || . . |. . || .. . | | ||| ||| | | |. | YRLVRKIGSGSFGDIYLGINITNGEEV-AIKMESNKAR-HPQLIYEAKVYRILQG---CVGIPHMRWYGCEKDYNVMVMDLLGPSLEDL--FNFCKRR-F SRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHLRKEQGRV . | . | . . ||| .|||||.|| |||.| . . ....|||||. . ..| . | | . || || | | || || | TMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNK---LFLIDFGLAKKYRDSRTR--QHIPYRE--DKNLTGTARYASINAHLGIEQSRR DDVWSLLYVIIELNGGKALPWQ-----TDSQR-ERVEQMKLNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMI ||. |. ||.. | || |||| | |. |.. |. | ... .|| . | . .| . . ||| . DDMESMGYVMMYFNRGK-LPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | W01B6.2.AA | CK1 | 24-179 | 32 | 1.6e-27 | 91.89 | In-house | 1-156 (271) | Show / Hide |
Range on Protein: 24-179 Range on HMM: 1-156/271 Sequence Identity: 32% (53 aa) WKIGKTIDEGGFGKVYIATSISDPKKV--AALKAESNEIEGGSAIKLEAMILNKLNA---NGPVPHIPVVHLCAKR--KLYCYMVMTLLGRNLRKLKSTN ..|. |..| || .| .. . . .. | | |.| . . .. || |.. |. ... ..|| .. |.. . | .|||.|||..| .|. YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSK-HPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFN-- LVVNNGFSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLA | || | |. | . . ||| ..|||||.|| ||| | .. .|.| ||||| -FCNRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGR--YGKHCHQVYIIDFGLA |
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Kinase | W01B6.2.AA | CK1-G | 123-294 | 31 | 4e-21 | 68.26 | In-house | 93-266 (266) | Show / Hide |
Range on Protein: 123-294 Range on HMM: 93-266/266 Sequence Identity: 31% (56 aa) FSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHLRKEQGR || | . || . ..|||. | ||||| ||| | . .......|| |||.|. . . .. |. | . || || | | || .|| | FSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGR-PSNKDQHVIHIIDFGMAKQY--IDPETKQHIPYREHKS--LTGTARYMSINTHLGREQSR VDDVWSLLYVIIELNGGKALPWQ---TDSQRERVEQM---KLNLPAKVVMSN--MPACMDKVMPHLASLDYYQRPDYHMI || .| . . |. |||| | .|| . | ... .. . | .| . . . .||. ||| . RDDMEALGHMFMYFLRGS-LPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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Kinase | W01B6.2.AA | Pkinase | 138-257 | 27 | 6.6e-19 | 67.94 | Pfam | 120-231 (293) | Show / Hide |
Range on Protein: 138-257 Range on HMM: 120-231/293 Sequence Identity: 27% (35 aa) ALKYVHDNGFIHRDVKPQNFLLG--NETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNVHL-RKEQGRVDDVWSLLYVII .|.| |..|.||||.||.|.|. ...|. .|.| |||||. | . . . | ||..| .| |.. ... |. |.||. ... GLEYCHSMGIIHRDLKPENILIDNNGHIDA----CVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILY ELNGGKALPWQTD------SQRERVEQMK |. |. .|.. . .|...... . EMLCGR-PPFPGHCWHDNHDQMQMICRIM |
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Kinase | W01B6.2.AA | CK1-Unique | 24-247 | 23 | 1.2e-17 | 57.8 | In-house | 1-235 (337) | Show / Hide |
Range on Protein: 24-247 Range on HMM: 1-235/337 Sequence Identity: 23% (57 aa) WKIGKTIDEGGFGKVYIATSISDP-----KKVAALKAESNEIEGG----SAIKLEAMILNKLNANGP-VPHIPVVHLCAKRKLYCYMVMTLLGRNLRKLK |.. | | ||.| |. .. .. . | | . . .... ..|. . | ..|| . . ..|||..|... .. WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC STNLVVNN-GFSRG------TWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDS-ERARIVHILDFGL-ARPFAVFHARENKWIARRARGTAEFR | | . . . | ||| .. | ||.||. || |. .. . | . .||.| | | | .| | | .. || ---MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYM--APSQQHQHCYYMLDYGICRRVFFV----SNNHQIRQPRPITPFR GTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGG-KALPWQTD |...| . |. .|.|| || |..| .. | .. . | |. | GCKDYCPCSCHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKLD |
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Kinase | W01B6.2.AA | CK1-Unclassified | 24-109 | 24 | 2.5e-16 | 44.73 | In-house | 1-90 (244) | Show / Hide |
Range on Protein: 24-109 Range on HMM: 1-90/244 Sequence Identity: 24% (23 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANG-----PVPHIPVVHLCAKRKL--YCYMVMTLLGRNL .... |. | || .| .. . . ...|.| |.. . . .. || |.. |. . . .|| .. |.. | .|||.|||..| YRVIEKIGQGSFGEIYKCINMQTN-EEVAIKLEKKNSK-HPQLCYEAKIMQYLQNGHNCDNFI-KGIPKMYWCGQEEQGDYNIMVMDLLGPSL |
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Kinase | W01B6.2.AA | S_TKc | 24-298 | 21 | 1.7e-14 | 35.64 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 24-298 Range on HMM: 1-231/231 Sequence Identity: 21% (64 aa) WKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPVPHIPVVHLCAKRKLYCYMVMTLLGR---NLRKLKSTNLVVN ..|...| .|.||||| .. .. ... |.| . |. | || | |.| . . . |||| ... .|... .. . YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK------EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY----IKKR NG------FSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHARENKWIARRARGTAEFRGTLRYTSPNV .. |. . .. | . ||.| |..|.||||.||.| || . . | |||||| . | ||. | .| | GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------HIKICDFGLARQL------------------TTFCGTPWYMAPEV HLRKEQGR-VDDVWSLLYVIIELNGGKALPWQTDSQRERVEQMKLNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMIFK---------CF |. |.||. ...|. |.. | ... .. . | . | . .. | .|| ... | L---GYGKCKCDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | W01B6.2.AA | CK1-Unclassified | 131-179 | 42 | 6.3e-13 | 34.5 | In-house | 109-155 (244) | Show / Hide |
Range on Protein: 131-179 Range on HMM: 109-155/244 Sequence Identity: 42% (21 aa) IGIQCLYALKYVHDNGFIHRDVKPQNFLLG-NETDSERARIVHILDFGLA |. | . . |.| ..||||| || ||| | . .. .|.| ||||. IADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGK---NHHQVYIIDFGLS |
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Kinase | W01B6.2.AA | CK1 | 205-292 | 31 | 1.7e-09 | 29.1 | In-house | 178-271 (271) | Show / Hide |
Range on Protein: 205-292 Range on HMM: 178-271/271 Sequence Identity: 31% (30 aa) GTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ---TDSQRERVEQ---MKLNLPAKVVMSN-MPACMDKVMPHLASLDYYQRPDYH || ||.| | || .||.| || || ||.. .. |. |||| ...... |. .|...| . .. |. . . . .|.....||| GTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGS-LPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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Kinase | W01B6.2.AA | TyrKc | 24-298 | 19 | 7.5e-07 | -111.87 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 24-298 Range on HMM: 1-280/280 Sequence Identity: 19% (62 aa) WKIGKTIDEGGFGKVYIATSISDPKKVA--ALKAESNEIEGGSAIKLEAMILNKL--NANGPVPHI-PVVHLCAKRK------LYCYMVMTL-----LGR . ||.. || ||.|| .| . .|| ||... .. || |. || . |.| . | . . ..|| . | ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHH----PNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD NLRKLKSTNLVVNNGFSRGTWSRIGIQCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPFAVFHA----RENKWIARRARGTAEF ||| . . .. . . .| | |....|||| | |.|.. .| | ||||.| .. . . . . . .. . . YLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------TVKISDFGLSR--DIYDDDQQGESKDYYRKKEHKGGKT RGTLRYTSPNVHLRKEQGRVDDVWS---LLYVIIELNGGKALPWQ-TDSQRERVEQMKLNLPAKVVMSNMPA--------CMDKVMPHLAS----LDYYQ .| ..| . .. |||| ... | . |. .. . ... .. . | .| | |.. . . | . MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPED RPDYHMIFKCF || | .|| RPTFSEIHECF |
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Kinase | W01B6.2.AA | CK1-Unclassified | 205-245 | 56 | 7.9e-07 | 16.21 | In-house | 178-217 (244) | Show / Hide |
Range on Protein: 205-245 Range on HMM: 178-217/244 Sequence Identity: 56% (23 aa) GTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ || ||.| | || .||.| || || ||.| . |. |||| GTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGS-LPWQ |
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Kinase | W01B6.2.AA | Pkinase | 24-51 | 39 | 4.4e-05 | 19.04 | Pfam | 1-28 (293) | Show / Hide |
Range on Protein: 24-51 Range on HMM: 1-28/293 Sequence Identity: 39% (11 aa) WKIGKTIDEGGFGKVYIATSISDPKKVA ..||..| .|.||.||... ....|.|| YHIGRKIGSGSFGCVYKCHHKGTGKIVA |
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Kinase | W01B6.2.AA | CK1-G | 24-51 | 28 | 0.016699 | 4.2 | In-house | 1-28 (266) | Show / Hide |
Range on Protein: 24-51 Range on HMM: 1-28/266 Sequence Identity: 28% (8 aa) WKIGKTIDEGGFGKVYIATSISDPKKVA ...|| | .| || .. . . || YRVGKKIGCGNFGELFEGKNMYNNEHVA |