Gene taf-1 (Nematode worm)
taf-1
Sequence
Protein domains of taf-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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DUF3591 | taf-1.AA | DUF3591 | 489-692 | 31 | 2.6e-50 | 178.24 | Pfam | 1-215 (494) | Show / Hide |
Range on Protein: 489-692 Range on HMM: 1-215/494 Sequence Identity: 31% (71 aa) FNL--SNDDYYVPKAT-SKT-----LSNNSLLIQHSTPATNIATHFFPTHPSAFRLRYWHRTPFTRRIVRHWQPMRFQPIQTPV------KHQQRVAAMR ||. |||.|| .. ... ..| | |.||.||.. ........ .| .|| .|. .| .| .. . ||. | . .| FNIIFSNDEYYDMLKENHQNKVRQTIGN--LNIEHSMPALRLQWPYYKVKLNKREARSFHRPHFQFYI---------RPGTQIWVRFSKLKHRKRKHDKR EAMRQAQGGGEVFYMRDVQDLSGKD-ETLVMIEYSEEHPVILSQPGMASKMKNYFKRRQAND-SEPTFT-FGELAFSHQ---IPF--LGQLQPGQSLQSI | |.. ...||| ||. .||...| ... .||.||.| ..|. ||.||..||.... ..| . |.. .|| .. | || .|.. ||. . . EKERMGKDISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDIGETHVLHPQDKSPFWNFGHVHPGEIVPTL ENMLYRAPIYLHKRQNTDFLLIRSMN .| .|||||. || .||||.|||.. YNNMYRAPIFKHKPEPTDFLCIRSTT |
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DUF3591 | taf-1.AA | DUF3591 | 736-996 | 35 | 3.2e-82 | 284.28 | Pfam | 217-494 (494) | Show / Hide |
Range on Protein: 736-996 Range on HMM: 217-494/494 Sequence Identity: 35% (98 aa) ASSNFRWYIRPLPSIFVAGQQCPLYEVPSPNSKRATVFVRDFLFAFIYRLFWASDSSPRRLKMDDVRNAF-PHYAESNIRKRLKMCSTFVRQGS---ETY .... ..|.|. . .|..||..|..||| |.|...| . ...| ...||||| . |...|....|. .| | |. .|.||| . . |.| . . GGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHRISIHDITKHFFPDQNEMQNRQRLKEFMKYQRDGGMDNQGW WSLKPDFRLPSK-EEVLSMVTPEMCCAQYSMMAAEQRLKDAGYGEKYFFTP-----ENDEGSE---DEVTIEDEIKCAPWNTTRAFLASQREKCLLDQTG | ||....||.. ||...|.||| ||. .|| ...|.|.||||... .|.. .|.. | .. |..| . |||||||.|. . . |..| | WKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEETKKVQMKIDLEQMMAPWNTTRNFINATQGKAMLQLHG IADPTGCGQGFSYVRV-SQKPH---KDENATPVPKKLVTGTNADLRKLPLKEAKQICRGYGVKEEEISALTRWEIIDV .|||||| |||..|. |.|.. ..| . . ||| |.||.|..|........| | ||| ||||. . .|. ... EGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKPKKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL |
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BROMO | taf-1.AA | BROMO | 1454-1562 | 25 | 3.7e-25 | 90.81 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 1454-1562 Range on HMM: 1-118/118 Sequence Identity: 25% (30 aa) RADPKVVMSSMLTDIVNELKMI--------SGSDAFVTPVNSKK--VVDYYNIIKNPISLQEIKKKISEQSYLLRKDFLDDIKLMFDNSRMYNGDNNILT . . . .....| ...... .. | ||. |. . |||.|||||..|. ||||. . | ...|.||..|||.| ..||. . . DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY LTAQQMLQLAGKRMIEREQ |... .. ... | .. KMAKKLQKFFEEKWREFPP |
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Bromodomain | taf-1.AA | Bromodomain | 1465-1548 | 26 | 1.1e-18 | 63.24 | Pfam | 1-89 (89) | Show / Hide |
Range on Protein: 1465-1548 Range on HMM: 1-89/89 Sequence Identity: 26% (24 aa) LTDIVN--ELKMISGSDAFVTPV--NSKKVVDYYNIIKNPISLQEIKKKISEQSYLLR--KDFLDDIKLMFDNSRMYNGDNNILTLTAQQ . |.. ... ...| || . ... |||.|||.|..|..|..|. .. | ..|. |..||. |...||| . .. |.. CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYR-NNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK |
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Bromodomain | taf-1.AA | Bromodomain | 1587-1670 | 31 | 6.3e-24 | 80.35 | Pfam | 1-89 (89) | Show / Hide |
Range on Protein: 1587-1670 Range on HMM: 1-89/89 Sequence Identity: 31% (28 aa) LGEIVQ--KMKNIPKSALFHTRV--DPKKIPAYYLKISDPMDLSIMEQKSKSQEYK-SIDEFLKDAEKIYTNSVVFNGAESVYSLKAKE . .|. .... | ...|. | |....| || .|..||||| ..|| |...|. .|.||..|.| ...|.. .|| .|.. |.. CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK |
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BROMO | taf-1.AA | BROMO | 1576-1684 | 24 | 4.4e-20 | 73.95 | SMART | 1-118 (118) | Show / Hide |
Range on Protein: 1576-1684 Range on HMM: 1-118/118 Sequence Identity: 24% (29 aa) DTNDLIGFSYLLGEIVQKMKNI--------PKSALFHTRVDPKK--IPAYYLKISDPMDLSIMEQKSKSQEYKSIDEFLKDAEKIYTNSVVFNGAESVYS | . .. || |.. .... | .. |. ||.|. .| || | ||||. ...| .. .|.|..||..| . . .| .|. .| . DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY LKAKEMFEMAEMLVKDQMD ||.. . | . .. .. KMAKKLQKFFEEKWREFPP |