T25B9.5

Species: Nematode worm
Alias: CE06504, T25B9.5, aSWK344
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: IV:4.71, WormBase Physical Map location: IV: 10754567-10752408

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
T25B9.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
T25B9.5.AA Protein Genbank 541 None Fasta, JSON

Protein domain

Protein domains of T25B9.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 T25B9.5.AA SH2 69-159 23 2.9e-13 51.32 SMART 1-87 (87) Show / Hide
Range on Protein: 69-159
Range on HMM: 1-87/87
Sequence Identity: 23% (23 aa)

LHVYHGVLFGSEAEKLLTW----DRAYLVRRAITKPNKFLCISVNWKKKIFHYQLDFNE-DGWCCKKLYEKFPTMPNRRFLHIRQLLEAWPQATPF
 . ||| . ..|||.|| .    | ..|||   .  ......|| ||.|. ||..  |. .....  .       ..|.|  . .|.. . .    
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDET-------WRRKFPSL-ELVNHYQHNPLG

Kinase T25B9.5.AA Fer 175-432 35 1.1e-135 457.03 In-house 1-283 (283) Show / Hide
Range on Protein: 175-432
Range on HMM: 1-283/283
Sequence Identity: 35% (101 aa)

INLDKKLGCGAFGEVFKGQ-----YKAVGSTNPPIEVAVKRILGN-AKRKQIQEFCNEAQIMTV-LQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYL
..|.||||.||||||.||.     .|..........|.||.  .. |...||.||..||.||   ..| |.|.|||....|.|||.|||...||.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

QTTQN--IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQ-DLKAK--ISDFGLSLQGTEVTTKNL-----EKAPIRWLAPESLKSGMFNEKTD
....|  ..  .........|.||..| ||..||||.||||||... ..| |  |||||.| |....... .     .|.||||||||....| ...|||
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VWSYGVFLTELMARCEHDPLY------PKSL-KDAKAWILTEERPHKMENGDPKELMVLID-ACCERNPNERLNFNTVKRQIT
|||.|| ..| ..........      .. . |.|..|| .......|.|..|.|.| ...  |....|..| ......... 
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK

Kinase T25B9.5.AA TyrKc 175-431 33 1.7e-112 380.91 SMART 1-280 (280) Show / Hide
Range on Protein: 175-431
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVL--QHENIVAFYGFASLE-------EPIMVVMELVTGGDLRK
| |.||||.||||||.||..|        |.|||| .  .|    ...|..||.||. |  .|.|||..|| .. .       ||.|.|||.. .|||..
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YLQTTQN-IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTEV--------TTKN----LEK--APIRWLAPESLKSG
||. ... ..  . | |.  .|.||..|.||..||||||||||||. .. .||||||||  ...         . .      .|   ||||.|||... |
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

MFNEKTDVWSYGVFLTELMARCEHDPLYP----KSLKDAKAWILTEERPHKMENG-------DPKELMVLIDACCERNPNERLNFNTVKRQI
.|..|.||||.|| . |.. ...  .  .    .| ... ... . .|. ...|.        |.|.  ..  |....|..| .|.......
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase T25B9.5.AA Pkinase_Tyr 175-431 36 2.1e-101 344.06 Pfam 1-270 (270) Show / Hide
Range on Protein: 175-431
Range on HMM: 1-270/270
Sequence Identity: 36% (101 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQ--IQEFCNEAQIMTVL-QHENIVAFYGFAS-LEEP--IMVVMELVTGGDLRKYLQ
| ..|||| ||||||.|| .|     |. |.|||| .  .|  .|  ...| .||.||. | .|.||| .||  .  .||  |..|||.. .|||..||.
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----TQNIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQG-----TEVTTKNLEKAPIRWLAPESLKSGMFNEKTDVW
.     |...  ..| ... .|.|| .|.||..||||||||||||| ....||.||||.          ....   | ||.|.|||... | |..|.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGVFLTELMARCEHDP-LYPKSLKDAKAWILTEERPHKMENGDPKELMVLIDACCERNPNERLNFNTVKRQI
|.|| . |.. ..|  |  .  |  . ...|  . .  ..  . |.|.  |.  | . .|..|  |  . .|.
SFGVLMWEIFTYGE-QPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase T25B9.5.AA TK 175-431 19 2.7e-88 296.05 In-house 1-486 (486) Show / Hide
Range on Protein: 175-431
Range on HMM: 1-486/486
Sequence Identity: 19% (95 aa)

INLDKKLGCGAFG---EVFKGQYKAVG--------------------STNPPIEVAVKRIL---GNAKRKQIQ----------EFCNEAQIMTVLQ----
| | |||| |.||   ||.||...  .                    ... ...|||| .    ..... ...          .|..||..| ...    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENIVAFYG-------------FASLEEPIMVVMELVTGGD----LRKYLQTTQN--------------------------------------------
 |.||| .||             . ...||.|.|||.. .||    ||.||..  .                                            
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------IPKLQILWFAMNVASGMRHLSSK------GIIHRDLAARNCLVTQDLK-----------AKISDFGLS
                                ..  | | ... .|.||..|.||      ...|||||||||||.....           .||.|||||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

LQGT-----------EVTTKN------------------------LEKAPIRWLAPESLKSGM---------FNEKTDVWSYGVFLTELMARCEHDPLYP
 ||.           . ..|.                          | ||||.|||.|...          | .|.||||.||.. |.. ...  .   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

KSL---------KDAKAWILTE--------------ERPHKMENGDP-------------KELMVLIDACCERNPNERLNFNTVKRQI
 |          ..    . ..               |. . ..  .             .|.. |.  |....|..| .| ....|.
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase T25B9.5.AA UTK 175-371 32 8.1e-64 217.19 In-house 1-236 (296) Show / Hide
Range on Protein: 175-371
Range on HMM: 1-236/296
Sequence Identity: 32% (77 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRIL-GNAKRKQIQ---EFCNEAQ---IMTVLQ-HENIVAFYGFASLEEPIMVVMELVTGGDLRKY
. | ..|| ||||||.|. .. .    .   ||||    . .....     .| .||.   .|  .. |.|.. ..|  . |||.|.|.|.  .||||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LQTTQNIP--------KLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQD-------LKAKISDFG---LSLQGT------------EVTTKNLEK
|..    |        . | | .|...|.|| .|.|.|..|||||||||||...       ...||.|||   .| .              ...  . ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

APIRWLAPESLKSG-MFNEKTDVWSYGVFLTELMAR
.|||| |||.| ..  | .|.||||.||.. |....
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTW

Kinase T25B9.5.AA TK-Unique 175-369 34 2.1e-60 206.93 In-house 1-233 (294) Show / Hide
Range on Protein: 175-369
Range on HMM: 1-233/294
Sequence Identity: 34% (80 aa)

INLDKKLGCGAFGEVFKGQYKAVG-STNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQ-HENIVAFYGFASLE-EPIMVVMELVTGGDLRKYLQTTQ
.......| ||||.|..|... .  . . .. ||||    ||   . |.| .|.|.|  |  |.||| ..|      || | .|| . .|.|..||.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-N-------------------------IPKLQILWFAMNVASGMRHLSS--KGIIHRDLAARNCLVTQDLKAKISDFGLS--LQGTEVTTKNLE--KAPI
 .                         |   . . ||  .|.|| .|.|  |.|.||||.|||.|.| |...||.|||..  .. ..|. .. .  . ||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWLAPESLK--SGMF-NEKTDVWSYGVFLTELM
||.||||||   ||. ..|.||||.||.. |..
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIF

Kinase T25B9.5.AA Src 175-369 39 3.5e-59 199.71 In-house 1-194 (255) Show / Hide
Range on Protein: 175-369
Range on HMM: 1-194/255
Sequence Identity: 39% (80 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYLQ---TTQ
| | .||| | ||||..| ..        ..|||| .       . . |  |||||. |.||..|. |   | ||||  | |. . | | .||.   ...
IKLCRKLGQGQFGEVWMGYWNGN------TKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

NIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLS--LQ--GTEVTTKNLEKAPIRWLAPESLKSGMFNEKTDVWSYGVFLTE
...  | . .|  ||.||  |.|. .||||||||| || ... .|. ||||   ..    | . .   | ||.| ||| .  | |. |.||||.|. |||
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE

LM
..
IV

Kinase T25B9.5.AA TKL 181-431 21 5.3e-58 199.02 In-house 1-364 (364) Show / Hide
Range on Protein: 181-431
Range on HMM: 1-364/364
Sequence Identity: 21% (82 aa)

LGCGAFGEVFKGQYKA---VGSTNPP----IEVAVKRILG---NAKRKQIQE---------------------FCNEAQIMTVLQ--HENIVAFYGFASL
.| |.||||.||...    ..    |     .||||..     . . |..||                     |. | .||  ..  |.||| |.|..  
IGSGGFGEVYKGKWRGWGGKC----PSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCC

EEP-------------IMVVMELVTGGDLRKYLQTTQNIPKLQILWFAMNVASGMRHLSS--------KGIIHRDLAARNCLVTQDLK------------
...             .. |||.. ||.|. ||.        |.. .|. .|.|| .| |        ..||||||  .|.|| ....            
PPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKISDFGLSLQGTEVT--------------------TKNLEKAPIRWLAPESLK----------------SGMFNEKTDVWSYGVFLTELMARC--EH
  .||.|||||   .. .                    |.. .   .||.||| |.                .. ..||.||.|.|. | |...||  ..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

DPLYPKSL-----KDAKAWILTEERPHKME------------NGDPKELMVLIDACCERNPNERLNFNTVKRQI
|. |.  .     ..  ...  . ..  .             .  |...  |.  |.. .|..|..|.... ..
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase T25B9.5.AA RTKB 175-363 36 3.4e-51 170.83 In-house 1-198 (264) Show / Hide
Range on Protein: 175-363
Range on HMM: 1-198/264
Sequence Identity: 36% (72 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIM-TVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYLQ---TT
. |..||| |||||||.....  .. |    .|.|.. . |   . |.|| |  .| .. .| |..   |    .|| ..  ||   | || ||    ..
VWLGEKLGNGAFGEVFQAWVRNRHM-NTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRAS

QNIPK----LQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSL--QGTEVTTKNLEKAPIRWLAPESLKSGMFNEKT-DVWSYGV
|  |      | . |.. .|.|| .|.....|||||.||| ||.|.|. ||.|||..   .. ...|  . . ||.|.||||...  .. |  ||||.||
QHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYET-TCTRLPIKWMAPESWAHRIYTTKSGDVWSFGV





Kinase T25B9.5.AA Csk 175-368 38 4.9e-49 165.48 In-house 1-190 (251) Show / Hide
Range on Protein: 175-368
Range on HMM: 1-190/251
Sequence Identity: 38% (78 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEP--IMVVMELVTGGDLRKYLQT--T
. | .. | | || |  |.|.          |||| | ...    .| |  || .|| |.|.| |.. |   |...  . .||| .  | |  || .   
LHLGECIGHGEFGDVMQGEYQNR-------KVAVKCIKCDG-NGMAQAFLAEASVMTQLRHPNLVQLIGVI-LHQKNHLYIVMEYMSKGNLVDYLRSRGR

QNIPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTEVTTKNLE-----KAPIRWLAPESLKSGMFNEKTDVWSYGVFL
. | . | | ||| |..||  | .| ..|||||||| ||  |. ||.|||||. .     .....     | || | ||| |. . |  | ||||.|..|
HVITRRQLLKFAMDVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKE----ECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILL

TEL
 |.
WEI

Kinase T25B9.5.AA Ack 175-363 37 1.1e-48 162.3 In-house 1-199 (266) Show / Hide
Range on Protein: 175-363
Range on HMM: 1-199/266
Sequence Identity: 37% (76 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNA---KRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPI-MVVMELVTGGDLRKYLQTT
| | .||| | || | .|. ..  . .  |.|||| .|.       . ...|  |..||. |.|...|  ||   |  |  | |.|| ..| |   |   
ITLCEKLGDGCFGVVWRGEWTN--PGGKHIQVAVK-CLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVV-LDQPMLMMVTELAPCGSLLDCLRKH

QN--IPKLQILW-FAMNVASGMRHLSSKGIIHRDLAARNCLVTQD-LKAKISDFGLS--LQGTEV--TTKNLE--KAPIRWLAPESLKSGMFNEKTDVWS
.   .. . .|. |.| .|.||| | .|..||||||||| |.  |  |.||.||||.  | . |   ...     | |. | |||.|. . |  . |||.
CRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWM

YGV
.||
FGV

Kinase T25B9.5.AA Src-Unclassified 219-369 35 3.9e-42 142.26 In-house 48-221 (284) Show / Hide
Range on Protein: 219-369
Range on HMM: 48-221/284
Sequence Identity: 35% (62 aa)

QIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGGDLRKYLQTTQ-NIPKLQIL-------------WFAMNVASGMRHLSSKGIIHRDLAA
.|  || |||||. ..| |.|. |.  | |||. .. |. . | |  .|..     . .| .               |  |||||  |.||...||||||
KILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGGGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAA

RNCLVTQDL-----KAKISDFGLS----LQGTEVTTKNLEKAPIRWLAPESLKSGMFNEKTDVWSYGVFLTELM
|| |.          .|. ||||      |  .   .   . |. | |||    | |. |.||||||. | |.|
RNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIM

Kinase T25B9.5.AA S_TKc 175-436 24 2.1e-40 141.46 SMART 1-231 (231) Show / Hide
Range on Protein: 175-436
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRKQIQEFCNEAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTG--GDLRKYLQTTQN
  . .|.| ||||.|.|.. |         .||.|.|         . ...| ||.   .|.||| .|..    . . .|||.. |  |||..|..  . 
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------IPKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKAKISDFGLSLQGTEVTTKNLEKAPIRWLAPESLKSGMFNE-KTDVWSYGVFL
      .|  ..  ..  ..... .. |.|||||||   | |...    ||.||||. |       .       ..||| |    ..  | |.|| |. |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

TELMARCEHDPLYPKSLKDAKAWILTEERPHKMENGDPKELMVLIDACCERNPNERLNFNTVKR----QITDIYM
 |.....   |..|  ..     |.            ..|.  .|. |....|..|.    . .       . ..
YEMLCGY---PPFP-QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase T25B9.5.AA Pkinase 175-431 23 2.8e-34 122.28 Pfam 1-293 (293) Show / Hide
Range on Protein: 175-431
Range on HMM: 1-293/293
Sequence Identity: 23% (70 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVKRILGNAKRK-QIQEFCN--EAQIMTVLQHENIVAFYGFASLEEPIMVVMELVTGG----DLRKYL
. . .|.| |.||.|.|.. |  |      .||||.|    ... . |.  .  |.|||  |.|.||| .|..   .  | .|||.. ||    ||  |.
YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

Q--TTQNI--PKLQILWFAMNVASGMRHLSSKGIIHRDLAARNCLVTQDLKA----KISDFGLSLQ--GTEVTTKNLEKAPIRWLAPESLK-SGMFNEKT
.     ..  .  ..  ..  ...|. .. |.|||||||   |.|. ..       ||.||||. |      .  .     ....||| .. . .   | 
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVWSYGVFLTELMARCEHDPLYPKS----LKDAKAWILTEERPHKMENGDP-----------------------KELMVLIDACCERNPNERLNFNTVKR
|.||.|. | |.. .    |..| .      . . ... . .. . .   |                       .|.  .|. |....|..|...  .. 
DMWSCGCILYEMLCGR---PPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

Q--I
   .
HPWF

Kinase T25B9.5.AA Src-Unclassified 175-209 40 7.8e-08 22.88 In-house 1-29 (284) Show / Hide
Range on Protein: 175-209
Range on HMM: 1-29/284
Sequence Identity: 40% (14 aa)

INLDKKLGCGAFGEVFKGQYKAVGSTNPPIEVAVK
. | .||| | ||||..| ..        ..||||
VHLLRKLGRGQFGEVWYGKWRGK------VDVAVK

Kinase T25B9.5.AA UTK 412-431 30 0.045945 2.86 In-house 277-296 (296) Show / Hide
Range on Protein: 412-431
Range on HMM: 277-296/296
Sequence Identity: 30% (6 aa)

ACCERNPNERLNFNTVKRQI
.|.. .| || .| ..  |.
RCWHYDPQERPDFEDLVQQM