Gene T25B9.4 (Nematode worm)

T25B9.4

Species: Nematode worm
Alias: aSWK365, T25B9.4=ZK593.9, T25B9.4, CE06503
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: IV:4.71, WormBase Physical Map location: IV: 10757650-10755738

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
T25B9.4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
T25B9.4.AA Protein Genbank 546 None Fasta, JSON

Protein domain

Protein domains of T25B9.4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 T25B9.4.AA SH2 14-108 30 9.4e-21 76.19 SMART 1-87 (87) Show / Hide 
Range on Protein: 14-108
Range on HMM: 1-87/87
Sequence Identity: 30% (31 aa)

QKFYHGYLPREDLPYVLKKK----GDFIFRVTERTVGKEQKKDIVLSIAWPTESVAMIDTKDIKNYLIERSA-NSVWLDL--KISFHSIDALYNHYRKNE
| .||| ..||.    ||.     |||. |  |.     ...|.|||. |          . .|.|.|.|.. .....|   . .|.|.  | |||..| 
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-----NPGDYVLSVRWK---------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNP

LV
|.
LG
Kinase T25B9.4.AA Fer 132-387 43 8.10000000001e-139 467.47 In-house 1-283 (283) Show / Hide 
Range on Protein: 132-387
Range on HMM: 1-283/283
Sequence Identity: 43% (124 aa)

INLIKKVGKGAYGEVFKG--TVTRGN-KTFNG---AIKAMRKDLD-AGNEKMKEVMAEARLMRS-LNHPNIVRCRGIAVLEQPVYIVIEFINGGGLDSYL
..|.|| |.||.|||.||  |..... |....   |.| .. . . |. |..||.|.|||.||. ..|||.|...|..|.|||..||.||.||| |||||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

KKNSQ-TLTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDN-KNLVK--LSDFGLSRK----GSVYRMK-KAMKMPTKWLAPESLTTFTFSGASD
|||.. |.....| ||.. ||.|.|..||. .||||||||||||.. |. .|  .||||.||.    |. |.|| ||.|.|..|||||...|...| ..|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

VYTFGVLLYEIYT-CQEPYLA----VKAGEA-----KRYILSGAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKLE
|..|||...||.| ..|||..    .|...      |..| .| .. .....|||. .|..|...| || .| ||| |..||.
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase T25B9.4.AA TyrKc 132-386 32 1.7e-81 277.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 132-386
Range on HMM: 1-280/280
Sequence Identity: 32% (94 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSL--NHPNIVRCRGIAVLE-------QPVYIVIEFINGGGLDSY
| |.|| | ||.|||.||| .      . |.| ...|       ... | |||.|..|  .||||||. |... .       .|..|| |.  .| |..|
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LKKNSQTLTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSRKGSVY-------RMKKA-----MK--MPTKWLAPESLTTFT
|.|.  .|.|...  ... .| | |. ||. .||||.||||||..... || |||||||..  .        ....      |  .| .|.|||.. . .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

FSGASDVYTFGVLLYEIYT-CQEPYLA-----VKAGEAKRYILSGAFPNFTKQ--------APPELNEIVKKSIYQLDPAKRDTMKVIVKKL
|. .|||. |||...||.| .|.||       ... |. .|. .|  .   .         .|.|. . . |.  . ||..| |.. |....
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase T25B9.4.AA TK 132-386 20 7.4e-78 260.42 In-house 1-486 (486) Show / Hide 
Range on Protein: 132-386
Range on HMM: 1-486/486
Sequence Identity: 20% (99 aa)

INLIKKVGKGAYG---EVFKG-------------------TVTRGNKTFNG----AIKAMRKDLDAGNEKMKE--------------VMAEARLMRS--L
| |.|| |.|..|   ||.||                   |....|.. .|    |.| .... ..  | ...               ..|. .|..  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHPNIVRCRG-------------IAVLEQPVYIVIEFINGGG----LDSYLKKNSQT-------------------------------------------
.||||||. |             . |...|..|| |. ..|     |..||.|.. .                                           
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD

--------------------------------LTMDQKNRMAISAAWGIEFMHSHDI------IHRDIAARNCLYDNKNL-----------VKLSDFGLS
                                ||| |.  |.  .| | |..||. .      .|||.|||||| ...|            .|..|||||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

RKGS-----------------------------------VYRMKKAMKMPTKWLAPESLTTFT---------FSGASDVYTFGVLLYEIYT-CQEPYLA-
|.||                                    ||... .|.| .|.|||.|.. .         |. .|||. ||||..||.| .||||   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

------------------VKAGE----------AKRYILS----------GAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKL
                  ...|             |. .           ...   ....|||. ... ..  ..||..| |.. ....|
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase T25B9.4.AA Pkinase_Tyr 132-386 37 3.9e-77 261.86 Pfam 1-270 (270) Show / Hide 
Range on Protein: 132-386
Range on HMM: 1-270/270
Sequence Identity: 37% (102 aa)

INLIKKVGKGAYGEVFKGTVT--RGNKTFNGAIKAMRKDLDAGNEK--MKEVMAEARLMRSL-NHPNIVRCRGIAV-LEQP--VYIVIEFINGGGLDSYL
| ..|| |.||.|||.||| .   .|..   |.| . |. .|  |   ... |.||..|..| .||||||. |. .  ..|  .||| |.  .| |..||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KKN---SQTLTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSRKG---SVY-RMKKAMKMPTKWLAPESLTTFTFSGASDVY
.|.    | ||| ..  |..  |.| |. .|. .||||.|||||| ...| || .||||.|     . | |...  |.| ||.|||.. .  |. .|||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

TFGVLLYEIYT-CQEP-YLAVKAGEAKRYI-LSGAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKL
 ||||..||.| ...| |  ..  | ..||  .|      . .|.|. .. |.   . ||..| |.. |. .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCW-HYDPEDRPTFSEIHEQL
Kinase T25B9.4.AA UTK 132-327 32 1.7e-57 195.28 In-house 1-235 (296) Show / Hide 
Range on Protein: 132-327
Range on HMM: 1-235/296
Sequence Identity: 32% (77 aa)

INLIKKVGKGAYGEVFKGTVTRGN---KTFNGAIKAMRKDLDAGNEKM--KEVMAEAR---LMRSLN-HPNIVRCRGIAVLEQPVYIVIEFINGGGLDSY
. | .. |.||.|||.|...|. .   ..   |.|. ... ||  |.    ..| |||   .|  .. |||..|  |. . |.| .||.|.  .| |.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LKKNSQT-------LTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNK-------NLVKLSDFG---LSRKGS------------VYRMKKAMK
| ....|       ||..|.  ||   | | ...||. ..|||.|||||| .         ...|..|||   .||  .             |..  . .
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

MPTKWLAPESLTTF-TFSGASDVYTFGVLLYEIYT
.| .| |||.||   .|. .|||. |||...||.|
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWT
Kinase T25B9.4.AA Abl 132-327 39 2.9e-52 172.41 In-house 1-193 (252) Show / Hide 
Range on Protein: 132-327
Range on HMM: 1-193/252
Sequence Identity: 39% (79 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFINGGGLDSYLKKNS-QTL
| . .|.| | ||||..|   | ..|   |.|... |    . ...| ..|| .|. . |||.|.  |.   | | ||. ||.  | |  ||.... ..|
IMMKHKLGGGQYGEVYEGVWKRHDCTV--AVKTLKED----TMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREEL

TMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSR--KGSVYRMKKAMKMPTKWLAPESLTTFTFSGASDVYTFGVLLYEIYT
.      ||   | |.... ... ||||.||||||  ....||. ||||.|  |. .|  .   | | || |||||   .||  |||. |||||.|| |
PAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIAT
Kinase T25B9.4.AA TK-Unique 132-327 29 1.2e-48 165.93 In-house 1-234 (294) Show / Hide 
Range on Protein: 132-327
Range on HMM: 1-234/294
Sequence Identity: 29% (70 aa)

INLIKKVGKGAYGEVFKGTVTRGN---KTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLN-HPNIVRCRGIAVLEQ-PVYIVIEFINGGGLDSYLKKN
... ...|.||.|.|..|.|....     .. ..  |.||   . .|. . . |...|..|  |||||.| |. .  . |..|..|.. .| |..||...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQ-DFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

SQT--------------LTMDQKNRMA-IS------AAWG----IEFMHS--HDIIHRDIAARNCLYDNKNLVKLSDFGLSRKGS---VYRMK-KAMKMP
 ..               .|  |.| . ||       ||.     |...|  . |.|||..|||.|  ... .|..|||..|...   || |. .  ..|
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

TKWLAPESLT--TFTF-SGASDVYTFGVLLYEIYT
 .|.|||||   . .. .  |||. ||||..|| |
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase T25B9.4.AA SFK-Src 132-327 36 5.8e-48 139.89 In-house 1-194 (259) Show / Hide 
Range on Protein: 132-327
Range on HMM: 1-194/259
Sequence Identity: 36% (74 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFINGGGLDSYLKK-NSQTL
| | || | | .|.|.||   | |.| . |.|     |  |    .| ..|| .|. | ||| ..   .     |.||. | .  | |  ||.  . . |
IRLEKKLGSGQFGDVWKG---RWNNTTEVAVKT----LKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSL

TMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSR---KGSV-YRMKKAMKMPTKWLAPESLTTFTFSGASDVYTFGVLLYEIY
.| |   ||   | |  ..     .||| |||| |  . | .|  |||.||   . .  |  ..  | | || |||  .. .||  |||  ||.|..|| 
RMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIV

T
|
T
Kinase T25B9.4.AA Src 132-327 35 1.9e-47 159.23 In-house 1-195 (255) Show / Hide 
Range on Protein: 132-327
Range on HMM: 1-195/255
Sequence Identity: 35% (71 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFINGGGLDSYLK--KNSQT
| |..| |.| .|||..|.    |.. . |.| ....      . .   .|| .| .| |...|.   .   | |.||| |. . | |  |||  .  ..
IKLCRKLGQGQFGEVWMGYW---NGNTKVAVKTLKPGT----MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRH

LTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSRKGS----VYRMKKAMKMPTKWLAPESLTTFTFSGASDVYTFGVLLYEI
| . |   ||   | | ... |  .|||| |||| | ...|..|  |||| |       .| ...  |.| || ||| ..  .|.  |||  ||.||.||
LHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEI

YT
 |
VT
Kinase T25B9.4.AA Frk 132-390 32 3e-47 161.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 132-390
Range on HMM: 1-260/260
Sequence Identity: 32% (87 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFINGGGLDSYLK---KNSQ
| ||...| | .|||. |   . | |   |.| ..    .|    .. ..||..|..| || ...   .  .|.|.||. | .  | |  ||.   .. .
IQLIRRLGSGQFGEVWEG---LWNNTTPVAVKTLK----PGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGR

TLTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSR---KGSV--YRMKKAMKMPTKWLAPESLTTFTFSGASDVYTFGVLLY
 . | |   ||   | |. .. |.  ||||.|||| | ...| .|. |||| |   |     |  .  ...| || |||   .  |.  |||. ||.||.
QCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLT

EIYT-CQEPYLAVKAGEAKRYILSGAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKLETWL
|| |  . ||  .   |    .  |         |..| ||. .  .. || || |   .  ||| ..
EIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLE-CWHSDPMKRPTFETLQWKLEDYF
Kinase T25B9.4.AA TKL 138-386 22 5e-46 159.23 In-house 1-364 (364) Show / Hide 
Range on Protein: 138-386
Range on HMM: 1-364/364
Sequence Identity: 22% (83 aa)

VGKGAYGEVFKGTVTR--GNKT-----FNGAIKAMRKDLDAGNEK------------------------MKEVMAEARLMRSLNHPNIVRCRGIAVLEQP
.|.|..|||.||.     | |         |.| .... |  ..|                        ...   |...|..|.|||||.. |..  ...
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------VYIVIEFINGGGLDSYLKKNSQTLTMDQKNRMAISAAWGIEFMHSHD--------IIHRDIAARNCLYDNKNL--------------
              .|| |.. || | .||        ..|. |.|...| |....||..        |||||.  .|.| |...               
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKLSDFGLSRKGSVYRMKKAM----------------KMPTK----WLAPESLT----------------TFTFSGASDVYTFGVLLYEIYTCQEPYLAV
.|..||||||  |    ....                .|.      |.||| |                  |..| ..||| ||..|.||.|...||   
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

KAGEAK---------RYILS-GAFPNFT------------KQAPPELNEIVKKSIYQLDPAKRDTMKVIVKKL
.  . .          .. . |  |               ...||.. .. ..   . || || ... |.|.|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDH-DPEKRPSFQEILKRL
Kinase T25B9.4.AA S_TKc 132-390 23 6.4e-44 153.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 132-390
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFING--GGLDSYLKKNSQ-
  ...|.||||.|.|.|.. .. .. .  ||| ..          . .. | ..... .|||||.. .. .  . .|.| |...|  | | .|.||.   
YEILRKIGKGAFGKVYKCRHKKTGRIV--AIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

----TLTMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLVKLSDFGLSRKGSVYRMKKAMKMPTKWLAPESLTTFTFSG-ASDVYTFGVLLY
     ..  .  ...   . ..|..||| |||||.   | | |.   .|..||||.|.       . .     ..||| |    ... ..|.. .|..||
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIYTCQEPYLAVKAGEAKRYILSGAFPNFTKQAPPELNEIVKKSIYQLDPAKRDTMKVIVK-----KLETWL
| .. . |.      .  . |.           .||. .   . . | ||.|| |   . .     |.  |.
EMLCGYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase T25B9.4.AA TKL-Unique 134-335 31 1.2e-40 141.07 In-house 1-237 (290) Show / Hide 
Range on Protein: 134-335
Range on HMM: 1-237/290
Sequence Identity: 31% (77 aa)

LIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVMAEARLMRSLN-HPNIVRCRGIAV----LEQPVYIVIEFINGGGLDSYLK----
 ..|.| |.||.|.||.  .  .    |||   .  |  ||.|.|   | ..|  |. |||||.. |. .     .   .|| |...|| |...|     
FWNKIGEGGYGQVYKGKWRGYPV----AIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

-----KNSQTLTMDQKNRMAISAAWGIEFMHSHD--IIHRDIAARNCLYDNK-----NLVKLSDFGLSRKGS-VYRMKKAMK---------MPTKWLAPE
     .|. .|.| |...||| .| | .. |. .  |||||.  .| | ||.     . .|..|||||.  |   .|.. ..           . |.|||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

SLTT--FTFSGASDVYTFGVLLYEIYTCQE------PYLAV
 |.   ...|  |||| ||. |.||.| .       || ..
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGM
Kinase T25B9.4.AA Pkinase 132-332 25 1.1e-35 127.32 Pfam 1-212 (293) Show / Hide 
Range on Protein: 132-332
Range on HMM: 1-212/293
Sequence Identity: 25% (54 aa)

INLIKKVGKGAYGEVFKGTVTRGNKTFNGAIKAMRKDLDAGNEKMKEVM-AEARLMRSLNHPNIVRCRGIAVLEQPVYIVIEFINGG----GLDSYLK-K
. ...|.|.|..|.|.|..    .|..  |.| ..|. .  ....  .  .|...|..||||||||....   .. .|.| |. .||     | .|.. .
YHIGRKIGSGSFGCVYKCHHKGTGKIV--AVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

NSQTL--TMDQKNRMAISAAWGIEFMHSHDIIHRDIAARNCLYDNKNLV----KLSDFGLSRK--GSVYRMKKAMKMPTKWLAPESLT-TFTFSGASDVY
.. ..  ....  ...   . |.|..||. |||||.   |.|.||.. .    |..||||...     ..  .       ..||| .      . ..|..
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

TFGVLLYEIYTCQEPY
 .|..||| .. . |.
SCGCILYEMLCGRPPF