Gene T20F10.1 (Nematode worm)
T20F10.1
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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T20F10.1.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 306 | Kinase domain by global Sugen HMM | Fasta, JSON |
T20F10.1.AA | Protein | Genbank | 908 | None | Fasta, JSON |
Protein domains of T20F10.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | T20F10.1.AA | NDR | 502-807 | 47 | 1.4e-213 | 665.96 | In-house | 1-350 (350) | Show / Hide |
Range on Protein: 502-807 Range on HMM: 1-350/350 Sequence Identity: 47% (169 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEAD--SPWIVRLFFSFQDDACLYFIMEYVPGGDMMT---LLIQKGI |..|..||.||||.|.||||.||...|||| ..|.....|.|.|||.|||||.|||| .||.|.|..||||. .||..|||.||||||| ||....| FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTG---------------------LRWTHDRRYYGPENDHHRVDSFSLPP |.||.|||||||..||||.||..|.||||.||||.|||..||||||||||||| ..|||...||. ..|.. |... FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN EVAAIDKS-------------VKVLNVR--QQTRRITAHSLVGTGNYMAPEVIAK-TGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNF . .|. ||||| | .|.|| |.|.||| .||||||... ||.||.||||| |.|.|||..| ||..||| |...|.||... SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT L-----DFTYCGNLSKECLMMIQQLIC-DASSRLGSHGKDVAERTAQVKNHPWF . .| .. |||.|. ..|..|.| |.. |||||| .. ..|.||.| WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG----KGVDEIKSHPFF |
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Kinase | T20F10.1.AA | AGC | 502-807 | 31 | 3.6e-177 | 462.76 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 502-807 Range on HMM: 1-395/395 Sequence Identity: 31% (129 aa) FTVISHIGVGAFGKVSLVRKN------DTRKVYAMKSLEKAD-VIMKQ--QAAHVKAE------------RDILAEAD----------SPWIVR-LFFSF | .. .|| |.|||| ||||. || |.|||| |.|.. ...|. . .|...| |.||.... .|.||. |..|| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDDAC--LYFIMEYVP--------GGDMMTLLIQKG-----IFEEDLARFYIAE-------LACAIEYVHN-VGFIHRD-LKPDNILIDQHGHIKLTDFG ||. |||.|||.| ||.....|...| .|.|. ||||.|| ...|.|| |. |.|||| |||.|||.|..||||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LCTG----------------LRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT----------RRITAHSLVG--TGNYMAPEVIAKTG ||. ..| |. .| . .. ... . . | . | ... | ......| | .|||||.. LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS------NMD-T-N-----K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL---- HNQSCDWWS--TGVILYEMVFGRVPFHDDTPG----------GTQHRIK------NWRNFL------DFTYCGNLSKECLMMIQQLIC-DASSRLGSHGK ....||||| |...|||..|. ||..|.|. . ..|. ||. . .|... ..|.|. |..|.| | . |||..|. YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGN DVA-ERTAQVKNHPWF |.. . . ..|||||| DFGDKGAEEIKNHPWF |
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Kinase | T20F10.1.AA | DMPK | 502-647 | 47 | 1.2e-101 | 251.84 | In-house | 1-147 (270) | Show / Hide |
Range on Protein: 502-647 Range on HMM: 1-147/270 Sequence Identity: 47% (70 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKG-IFEED | ... || |.|| | .|| |..||||| . |.. . . . | .. ||||.. ..|.||..|.. |||. ||..||| ||||. ||. . . ..|| FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED LARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLC .||||.||. || .|. |..||| ||||.|.| |||||| ||| | MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC |
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Kinase | T20F10.1.AA | S_TKc | 502-807 | 30 | 1.9e-93 | 317.66 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 502-807 Range on HMM: 1-231/231 Sequence Identity: 30% (97 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPG--GDMMTLLIQKGI--- .... .|| |||||| ..|...| ...|.| . |.. |..|| . . |.||.|. .||| .||..|||..| ||..... ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT | | ||||.....||.|| |. |.|||||||.|||.|. |||..||||.. | RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------- RRITAHSLVGTGNYMAPEVIAKTGHNQ-SCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLIC-DASSRLGSHG ....|| .||||||. |.. .||||| |.|||||. |. ||. .. . ..|. |.|.. .|... . | . |.. -----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-E KDVAERTAQVKNHPWF . .. .|.|||| --ALQDEWDIKCHPWF |
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Kinase | T20F10.1.AA | RSK | 505-807 | 34 | 7.2e-93 | 314.84 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 505-807 Range on HMM: 1-278/278 Sequence Identity: 34% (112 aa) ISHIGVGAFGKVSLVRKN---DTRKVYAMKSLEKADVIMKQQ-AAHVKAERDILAEAD-SPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGI--- .. | |..|||.|.|| ||...|||| |.|| .. .| ..|...||.||.. .| ||.|. .||.. || ||||..||.. | | .... LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQ---HGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT | || |.||.||...|.|. | |.|||||||.||| |. .|||||||||.| . FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------------------- RRIT----AHSLVGTGNYMAPEVIA----KTGHNQSCDWWSTGVILYEMVFGRVPFHD---DTPGGTQHRIKNWRNFLDFTYC--GNLSKECLMMIQQLI |. ... ..| .|||||... . ||...||||| ||..||| .|..||. ... . ||.. . ...| .||.|. |... -RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKML C-DASSRLGSHGKDVAERTAQVKNHPWF . | . |||. .|..| .|.|||| HRDPHKRLGCGPQDAEE----IKQHPWF |
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Kinase | T20F10.1.AA | AktR | 502-807 | 36 | 4.1e-91 | 309.0 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 502-807 Range on HMM: 1-268/268 Sequence Identity: 36% (115 aa) FTVISHIGVGAFGKVSLVRKN-DTRKVYAMKSLEKADVIMKQQAAHVKAERDILA-EADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEE |.|. ..| |||||| ||.|. |. |.||||.. | . | ..|. |. ||.|.. ... | ||.|...||.. .|.|||||.|||.. . | .|. |.| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DLARFYIAELACAIEYVHNV-GFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITA . ||||.|. |.|| |. | |||||.|||.|..||.|.||||| .... .. .| EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------------LQFMMH--YDEKA HSLVGTGNYMAPEVIAK-TGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQ-QLICDASS-RLGSHGKDVA .|..|| |||||.| | ||| |.|||. |. .||||.| || .. ..||. . . |.| ..|..| || .| |. |||. . YSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY----YC ERTAQVKNHPWF . . ..|.|||| NGWEEIKSHPWF |
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Kinase | T20F10.1.AA | MAST | 502-646 | 49 | 5.8e-79 | 254.12 | In-house | 1-145 (334) | Show / Hide |
Range on Protein: 502-646 Range on HMM: 1-145/334 Sequence Identity: 49% (72 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDL |. | .|. ||.||| ||....|.. .||| . |.| | | . .|..||.|||....|..| .| ||| . |...|||. ||| .|| | |.|.. FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM ARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGL |..||||.. ..|| |. | .||||||||.||| |||||||||| AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL |
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Kinase | T20F10.1.AA | MAST | 502-646 | 46 | 1.5e-78 | 239.47 | In-house | 1-148 (337) | Show / Hide |
Range on Protein: 502-646 Range on HMM: 1-148/337 Sequence Identity: 46% (69 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQD--DACLYFIMEYVPGGDMMTLLIQKG-IFE | | .|..||.|.| ||.. .|.. .|||.. . | | | | .|..||.||.... |..| .| ||| . |...|||. ||| .|| | .. FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP EDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGL |..|..||||. ..|| |. | .||||||||.||| |||||||||| EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGL |
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Kinase | T20F10.1.AA | Akt | 502-647 | 52 | 4.2e-77 | 246.0 | In-house | 1-148 (264) | Show / Hide |
Range on Protein: 502-647 Range on HMM: 1-148/264 Sequence Identity: 52% (77 aa) FTVISHIGVGAFGKVSLVRKNDTRKVY-AMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEED |... .| |.|||| ||.|.|| |.| |||.| | |.| | .|.|.|| || ..| || | .|||. |||.|.|..||. ..| .|..| || FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED LARFYIAELACAIEYVHNVGFIHRD-LKPDNILIDQHGHIKLTDFGLC ||||.||. .|||. |. . | || ||| |||.|..|||.||||||| RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC |
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Kinase | T20F10.1.AA | CRIK | 502-645 | 47 | 5.5e-67 | 212.46 | In-house | 1-145 (272) | Show / Hide |
Range on Protein: 502-645 Range on HMM: 1-145/272 Sequence Identity: 47% (69 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKG-IFEED | | . || | || | .|| | .|||| . |. | ..| . .. ||||.. . |||. .| . |||. || .||| |||| |. . |.|. FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN LARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFG .|||| ||| |. .| |..||| ||.||||| ||||| ||| MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFG |
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Kinase | T20F10.1.AA | PKA | 502-645 | 46 | 1.6e-63 | 217.34 | In-house | 1-146 (263) | Show / Hide |
Range on Protein: 502-645 Range on HMM: 1-146/263 Sequence Identity: 46% (68 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVR-LFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEED | | .| | ||.| |.|. .. . |||| | |.... | ||. |. || . ..| ||. . ..|||| ||..|||||||.| . | .| | .. FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP LARFYIA-ELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFG |.||.| . .|.|| |. |.||||| |||||. ||||.|||| HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG |
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Kinase | T20F10.1.AA | Pkinase | 502-647 | 35 | 2.4e-51 | 181.69 | Pfam | 1-159 (293) | Show / Hide |
Range on Protein: 502-647 Range on HMM: 1-159/293 Sequence Identity: 35% (57 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVK-AERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGG----DMMTLLI--QK ..... || |.||.| . .. .|.|..|.| ..| . .... .|.. .| |... ..| ||||. .|.|. .|..|||..|| | .... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH GIF--EEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHI----KLTDFGLC | | .|. ..||. ......|| |. |.|||||||.|||||..||| |..||||. GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA |
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Kinase | T20F10.1.AA | DMPK | 702-807 | 36 | 1.2e-36 | 87.43 | In-house | 162-270 (270) | Show / Hide |
Range on Protein: 702-807 Range on HMM: 162-270/270 Sequence Identity: 36% (42 aa) VGTGNYMAPEVIAKTGHN------QSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNW-RNFLDFTYCGN--LSKECLMMIQQLICDASSRLGSHGK ||| |..||| . . .||||| ||..|||..|. ||..|. .| | | .|.|.| .|.| .|.||.||.. ||| | VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY DVAERTAQVKNHPWF . . |.||.| E------DFKCHPFF |
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Kinase | T20F10.1.AA | CRIK | 702-807 | 35 | 5.4e-24 | 73.08 | In-house | 162-272 (272) | Show / Hide |
Range on Protein: 702-807 Range on HMM: 162-272/272 Sequence Identity: 35% (43 aa) VGTGNYMAPEVI--------AKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKN------WRNFLDFTYCGNLSKECLMMIQQLICDASSRL ||| |||||| | . .||||| |.| |||. |. |||.|. | | | . || | .| . . ||.|.|. | || VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL GSHGKDVAERTAQVKNHPWF . |...|| | KYE---------QLCCHPFF |
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Kinase | T20F10.1.AA | MAST | 702-807 | 33 | 4.7e-23 | 66.71 | In-house | 229-337 (337) | Show / Hide |
Range on Protein: 702-807 Range on HMM: 229-337/337 Sequence Identity: 33% (38 aa) VGTGNYMAPEVIAKTG-HNQSCDWWSTGVILYEMVFGRVPFHDDTPGG-TQHRIKNWRNFLDFTYC--GN----LSKECLMMIQQLI-CDASSRLGSHGK .|| |.||||| ..| .... |||| |.|.|| | .|| .||| . |.| . . . .| .|.| |..| . . |||. | CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANG- DVAERTAQVKNHPWF ...|.|| | -----ADEIKQHPFF |
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Kinase | T20F10.1.AA | Akt | 697-744 | 38 | 1.2e-20 | 62.61 | In-house | 158-206 (264) | Show / Hide |
Range on Protein: 697-744 Range on HMM: 158-206/264 Sequence Identity: 38% (19 aa) TAHSLVGTGNYMAPEVIAKTGHNQSCDWWS-TGVILYEMVFGRVPFHDD .. .. || |.|||.. ..|| ...|||. .|...||| .|| ||... KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQ |
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Kinase | T20F10.1.AA | MAST | 700-807 | 35 | 1.2e-20 | 62.93 | In-house | 223-334 (334) | Show / Hide |
Range on Protein: 700-807 Range on HMM: 223-334/334 Sequence Identity: 35% (42 aa) SLVGTGNYMAPEVIAKTG-HNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWR---NFLDFTYCGN----LSKECLMMIQQLI-CDASSRLGSH ...|| |.||||| ..| |... |||| |.|.|| | .|| |||| . |.| . . . .. .| .|.| |..| .| . |||. QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN -GKDVAERTAQVKNHPWF | ..||.|| | NG------ADEVKQHPFF |
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Kinase | T20F10.1.AA | Pkinase | 698-807 | 26 | 5.1e-18 | 64.79 | Pfam | 168-293 (293) | Show / Hide |
Range on Protein: 698-807 Range on HMM: 168-293/293 Sequence Identity: 26% (36 aa) AHSLVGTGNYMAPEVIA-KTGHNQSCDWWSTGVILYEMVFGRVPFHDD----TPGGTQHRIKNWRNFLDFTYCG--------------------NLSKEC .....|| .||||||| ... ...|.|| |.|||||..|| || .. . ...|.. . . |.|.|| MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC LMMIQQLIC-DASSRLGSHGKDVAERTAQVKNHPWF . | ..| | ..|.. .|...|||| KDFIKWCLCKDPKKRPT---------AEQILQHPWF |
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Kinase | T20F10.1.AA | PKA | 703-746 | 46 | 4.7e-15 | 56.35 | In-house | 160-206 (263) | Show / Hide |
Range on Protein: 703-746 Range on HMM: 160-206/263 Sequence Identity: 46% (22 aa) GTGNYMAPEVIAKT-GHNQSCDWWSTGVILYEMVFGRVPFHDD--TP || |.|||.| . ||. | |||. |.. |||..| || |. .| GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDP |
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Kinase | T20F10.1.AA | TyrKc | 502-780 | 20 | 1.2e-09 | -66.88 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 502-780 Range on HMM: 1-280/280 Sequence Identity: 20% (66 aa) FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEA--DSPWIVRLFFSFQDD-------ACLYFIMEYVPGGDMMTLLI | . .| ||||.| . . . ..| | |.| . . | |. . . | ||||. .. |. .|||.|.|| | ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR QKGI-FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPE------NDHHRVDSFSLPPEVAAIDKSVK .. . . . || || | ..||||| |.|.. ...| .||||. |. . . | |. . |. | KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS---------RDIYDDDQQGESKDYYRKKE----------HKGGK -VLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMV-FGRVPFHD---------DTPGGTQHRIKNWRNFL--------DFTYCG .| .| ||||.| . . | || || ..|. .| | . . ... . . TMLPIR----------------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY NLSKECLMM----------IQQLI .. |.| . | ... QIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | T20F10.1.AA | Pkinase_Tyr | 575-647 | 31 | 2.3e-09 | 32.34 | Pfam | 82-158 (270) | Show / Hide |
Range on Protein: 575-647 Range on HMM: 82-158/270 Sequence Identity: 31% (24 aa) LYFIMEYVPGGDMMTLLIQ----KGIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLC .| .|||.|.||. . | . |. . . .. |.. || .. ..||||| |.|.. ...| .||||. IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
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Kinase | T20F10.1.AA | S_TK_X | 808-866 | 22 | 2e-06 | 28.88 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 808-866 Range on HMM: 1-79/79 Sequence Identity: 22% (18 aa) RGIDWVNLRK--LRADYIYIPRVT----HDEDTSNFE-TFQDNDRADKPN----VRGLHNPA---------FYEFTYRH ||||| .|.. . ..|... ...|||||. | ... ..| ... .... | .|||.. RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF |
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Kinase | T20F10.1.AA | Pkinase_C | 827-868 | 21 | 1.1e-05 | 23.27 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 827-868 Range on HMM: 1-46/46 Sequence Identity: 21% (11 aa) RVTHDEDTSNFET----------FQDNDRADKPNVRGLHNPAFYEFTYRHFF .|....|||||.. . |.. . .. .| |||.... QVKSPTDTSNFDPEFTDEPPMDTP-----PDWR-MSSGDQEPFRGFTYVNPD |
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Kinase | T20F10.1.AA | Akt | 786-807 | 45 | 0.001175 | 7.47 | In-house | 247-264 (264) | Show / Hide |
Range on Protein: 786-807 Range on HMM: 247-264/264 Sequence Identity: 45% (10 aa) RLGSHGKDVAERTAQVKNHPWF |||.. .|. | .|.|||| RLGGGPNDAQE----IKRHPWF |
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Kinase | T20F10.1.AA | PKA | 782-807 | 30 | 0.001395 | 13.1 | In-house | 242-263 (263) | Show / Hide |
Range on Protein: 782-807 Range on HMM: 242-263/263 Sequence Identity: 30% (8 aa) DASSRLGSHGKDVAERTAQVKNHPWF | . |.|.. .. ..|||.|| DLTKRYGNMKN----GVNDIKNHKWF |
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Kinase | T20F10.1.AA | Pkinase_Tyr | 502-516 | 46 | 1.418051 | 2.57 | Pfam | 1-15 (270) | Show / Hide |
Range on Protein: 502-516 Range on HMM: 1-15/270 Sequence Identity: 46% (7 aa) FTVISHIGVGAFGKV | . .| ||||.| ITFGKKLGEGAFGEV |