T20F10.1

Species: Nematode worm
Alias: aSWK009, CE13844, T20F10.1
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:4.45, WormBase Physical Map location: I: 10305973-10299945,

Classification

Group: AGC
Family: NDR
Subfamily: LATS

Sequence

Name Sequence Type Origin Length Description Download
T20F10.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 306 Kinase domain by global Sugen HMM Fasta, JSON
T20F10.1.AA Protein Genbank 908 None Fasta, JSON

Protein domain

Protein domains of T20F10.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T20F10.1.AA NDR 502-807 47 1.4e-213 665.96 In-house 1-350 (350) Show / Hide
Range on Protein: 502-807
Range on HMM: 1-350/350
Sequence Identity: 47% (169 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEAD--SPWIVRLFFSFQDDACLYFIMEYVPGGDMMT---LLIQKGI
|..|..||.||||.|.||||.||...|||| ..|.....|.|.|||.|||||.||||  .||.|.|..||||. .||..|||.|||||||   ||....|
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTG---------------------LRWTHDRRYYGPENDHHRVDSFSLPP
|.||.|||||||..||||.||..|.||||.||||.|||..|||||||||||||                     ..|||...||.  ..|.. |...   
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

EVAAIDKS-------------VKVLNVR--QQTRRITAHSLVGTGNYMAPEVIAK-TGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNF
.    .|.             ||||| |  .|.||  |.|.||| .||||||... ||.||.||||| |.|.|||..|  ||..|||  |...|.||...
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----DFTYCGNLSKECLMMIQQLIC-DASSRLGSHGKDVAERTAQVKNHPWF
.     .| .. |||.|. ..|..|.| |.. ||||||    ..  ..|.||.|
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG----KGVDEIKSHPFF

Kinase T20F10.1.AA AGC 502-807 31 3.6e-177 462.76 In-house 1-395 (395) Show / Hide
Range on Protein: 502-807
Range on HMM: 1-395/395
Sequence Identity: 31% (129 aa)

FTVISHIGVGAFGKVSLVRKN------DTRKVYAMKSLEKAD-VIMKQ--QAAHVKAE------------RDILAEAD----------SPWIVR-LFFSF
| .. .|| |.|||| ||||.      || |.|||| |.|.. ...|.  . .|...|            |.||....          .|.||. |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDAC--LYFIMEYVP--------GGDMMTLLIQKG-----IFEEDLARFYIAE-------LACAIEYVHN-VGFIHRD-LKPDNILIDQHGHIKLTDFG
||.    |||.|||.|        ||.....|...|     .|.|. ||||.||       ...|.|| |.  |.|||| |||.|||.|..|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCTG----------------LRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT----------RRITAHSLVG--TGNYMAPEVIAKTG
||.                 ..| |. .| . ..      ... . .     |  .  | ...            | ......|  | .|||||..    
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS------NMD-T-N-----K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----

HNQSCDWWS--TGVILYEMVFGRVPFHDDTPG----------GTQHRIK------NWRNFL------DFTYCGNLSKECLMMIQQLIC-DASSRLGSHGK
....|||||   |...|||..|. ||..|.|.           . ..|.      ||.  .      .|... ..|.|.   |..|.| | . |||..|.
YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGN

DVA-ERTAQVKNHPWF
|.. . . ..||||||
DFGDKGAEEIKNHPWF

Kinase T20F10.1.AA DMPK 502-647 47 1.2e-101 251.84 In-house 1-147 (270) Show / Hide
Range on Protein: 502-647
Range on HMM: 1-147/270
Sequence Identity: 47% (70 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKG-IFEED
| ... || |.|| | .||   |..||||| . |.. . . . | .. ||||.. ..|.||..|.. |||.  ||..||| ||||. ||. . .  ..||
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

LARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLC
.||||.||.  ||  .|. |..||| ||||.|.| |||||| ||| |
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSC

Kinase T20F10.1.AA S_TKc 502-807 30 1.9e-93 317.66 SMART 1-231 (231) Show / Hide
Range on Protein: 502-807
Range on HMM: 1-231/231
Sequence Identity: 30% (97 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPG--GDMMTLLIQKGI---
.... .|| |||||| ..|...| ...|.| .            |.. |..|| . . |.||.|. .|||  .||..|||..|  ||..... ..|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT
   | |  ||||.....||.|| |. |.|||||||.|||.|.  |||..||||.. |                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

RRITAHSLVGTGNYMAPEVIAKTGHNQ-SCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQQLIC-DASSRLGSHG
     ....|| .||||||.   |..  .||||| |.|||||. |. ||.  ..  . ..|.              |.|.. .|... . | . |..   
-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-E

KDVAERTAQVKNHPWF
  . ..   .|.||||
--ALQDEWDIKCHPWF

Kinase T20F10.1.AA RSK 505-807 34 7.2e-93 314.84 In-house 1-278 (278) Show / Hide
Range on Protein: 505-807
Range on HMM: 1-278/278
Sequence Identity: 34% (112 aa)

ISHIGVGAFGKVSLVRKN---DTRKVYAMKSLEKADVIMKQQ-AAHVKAERDILAEAD-SPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGI---
..  | |..|||.|.||    ||...|||| |.|| .. .|  ..|...||.||..   .| ||.|. .||..  || ||||..||.. | | ....   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQ---HGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQT
| || |.||.||...|.|. |  |.|||||||.||| |.   .|||||||||.|  .                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

RRIT----AHSLVGTGNYMAPEVIA----KTGHNQSCDWWSTGVILYEMVFGRVPFHD---DTPGGTQHRIKNWRNFLDFTYC--GNLSKECLMMIQQLI
 |.     ... ..| .|||||...    . ||...||||| ||..||| .|..||.    ...  .  ||.. .  ...|     .||.|.   |... 
-RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGK--FSLTMPNWQYLSQEAKDLIRKML

C-DASSRLGSHGKDVAERTAQVKNHPWF
. | . |||.  .|..|    .|.||||
HRDPHKRLGCGPQDAEE----IKQHPWF

Kinase T20F10.1.AA AktR 502-807 36 4.1e-91 309.0 In-house 1-268 (268) Show / Hide
Range on Protein: 502-807
Range on HMM: 1-268/268
Sequence Identity: 36% (115 aa)

FTVISHIGVGAFGKVSLVRKN-DTRKVYAMKSLEKADVIMKQQAAHVKAERDILA-EADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEE
|.|. ..| |||||| ||.|. |. |.||||.. | . | ..|. |.  ||.|.. ... | ||.|...||.. .|.|||||.|||.. . | .|. |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DLARFYIAELACAIEYVHNV-GFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPENDHHRVDSFSLPPEVAAIDKSVKVLNVRQQTRRITA
. ||||.|.   |.|| |.    | |||||.|||.|..||.|.|||||                                        ....   .. .|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------------------------LQFMMH--YDEKA

HSLVGTGNYMAPEVIAK-TGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWRNFLDFTYCGNLSKECLMMIQ-QLICDASS-RLGSHGKDVA
.|..||  |||||.| |  ||| |.|||. |. .||||.|  || ..      ..||. .  . |.|  ..|..|   || .| |.    |||.     .
YSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY----YC

ERTAQVKNHPWF
. . ..|.||||
NGWEEIKSHPWF

Kinase T20F10.1.AA MAST 502-646 49 5.8e-79 254.12 In-house 1-145 (334) Show / Hide
Range on Protein: 502-646
Range on HMM: 1-145/334
Sequence Identity: 49% (72 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEEDL
|. | .|. ||.||| ||....|.. .||| . |.| | | .  .|..||.|||....|..| .| ||| .  |...|||. |||  .||   | |.|..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGL
|..||||.. ..|| |. | .||||||||.|||  ||||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGL

Kinase T20F10.1.AA MAST 502-646 46 1.5e-78 239.47 In-house 1-148 (337) Show / Hide
Range on Protein: 502-646
Range on HMM: 1-148/337
Sequence Identity: 46% (69 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQD--DACLYFIMEYVPGGDMMTLLIQKG-IFE
|  | .|..||.|.| ||.. .|.. .|||.. . | | | |  .|..||.||.... |..| .| |||   .  |...|||. |||  .||   |  ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGL
|..|..||||.  ..|| |. | .||||||||.|||  ||||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGL

Kinase T20F10.1.AA Akt 502-647 52 4.2e-77 246.0 In-house 1-148 (264) Show / Hide
Range on Protein: 502-647
Range on HMM: 1-148/264
Sequence Identity: 52% (77 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVY-AMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEED
|...  .| |.|||| ||.|.|| |.| |||.| |   |.| | .|.|.|| ||   ..| || | .|||.   |||.|.|..||.  ..| .|..| ||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

LARFYIAELACAIEYVHNVGFIHRD-LKPDNILIDQHGHIKLTDFGLC
 ||||.||. .|||. |. . | || ||| |||.|..|||.|||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC

Kinase T20F10.1.AA CRIK 502-645 47 5.5e-67 212.46 In-house 1-145 (272) Show / Hide
Range on Protein: 502-645
Range on HMM: 1-145/272
Sequence Identity: 47% (69 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGGDMMTLLIQKG-IFEED
| | . || | || | .||   |  .|||| . |. |  ..| . .. ||||.. . |||. .| . |||.  || .||| ||||   |.   .  |.|.
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

LARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFG
.|||| |||  |.  .|  |..||| ||.|||||  ||||| |||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFG

Kinase T20F10.1.AA PKA 502-645 46 1.6e-63 217.34 In-house 1-146 (263) Show / Hide
Range on Protein: 502-645
Range on HMM: 1-146/263
Sequence Identity: 46% (68 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEADSPWIVR-LFFSFQDDACLYFIMEYVPGGDMMTLLIQKGIFEED
|  |  .| | ||.| |.|. .. . |||| | |....   |  ||. |. || . ..| ||. . ..||||  ||..|||||||.| . |  .| | ..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

LARFYIA-ELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFG
 |.||.| .  .|.|| |.   |.||||| |||||. ||||.||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFG

Kinase T20F10.1.AA Pkinase 502-647 35 2.4e-51 181.69 Pfam 1-159 (293) Show / Hide
Range on Protein: 502-647
Range on HMM: 1-159/293
Sequence Identity: 35% (57 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVK-AERDILAEADSPWIVRLFFSFQDDACLYFIMEYVPGG----DMMTLLI--QK
..... || |.||.| . .. .|.|..|.| ..| .  .... .|.. .|  |... ..| ||||. .|.|.  .|..|||..||    | ....   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GIF--EEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHI----KLTDFGLC
| |  .|. ..||. ......|| |. |.|||||||.|||||..|||    |..||||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLA

Kinase T20F10.1.AA DMPK 702-807 36 1.2e-36 87.43 In-house 162-270 (270) Show / Hide
Range on Protein: 702-807
Range on HMM: 162-270/270
Sequence Identity: 36% (42 aa)

VGTGNYMAPEVIAKTGHN------QSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNW-RNFLDFTYCGN--LSKECLMMIQQLICDASSRLGSHGK
|||  |..|||    . .       .||||| ||..|||..|. ||..|.  .|   | |  .|.|.|       .|.|   .|.||.||.. |||  | 
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

DVAERTAQVKNHPWF
.      . |.||.|
E------DFKCHPFF

Kinase T20F10.1.AA CRIK 702-807 35 5.4e-24 73.08 In-house 162-272 (272) Show / Hide
Range on Protein: 702-807
Range on HMM: 162-272/272
Sequence Identity: 35% (43 aa)

VGTGNYMAPEVI--------AKTGHNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKN------WRNFLDFTYCGNLSKECLMMIQQLICDASSRL
|||  ||||||          |  .  .||||| |.| |||. |. |||.|.   |   | |       . || |     .| . .  ||.|.|. | ||
VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL

GSHGKDVAERTAQVKNHPWF
.           |...|| |
KYE---------QLCCHPFF

Kinase T20F10.1.AA MAST 702-807 33 4.7e-23 66.71 In-house 229-337 (337) Show / Hide
Range on Protein: 702-807
Range on HMM: 229-337/337
Sequence Identity: 33% (38 aa)

VGTGNYMAPEVIAKTG-HNQSCDWWSTGVILYEMVFGRVPFHDDTPGG-TQHRIKNWRNFLDFTYC--GN----LSKECLMMIQQLI-CDASSRLGSHGK
.||  |.||||| ..| .... |||| |.|.||   | .|| .|||   .   |.|  . . .     .|    .|.|    |..|   . . |||. | 
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANG-

DVAERTAQVKNHPWF
      ...|.|| |
-----ADEIKQHPFF

Kinase T20F10.1.AA Akt 697-744 38 1.2e-20 62.61 In-house 158-206 (264) Show / Hide
Range on Protein: 697-744
Range on HMM: 158-206/264
Sequence Identity: 38% (19 aa)

TAHSLVGTGNYMAPEVIAKTGHNQSCDWWS-TGVILYEMVFGRVPFHDD
.. .. ||  |.|||.. ..|| ...|||. .|...||| .|| ||...
KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQ

Kinase T20F10.1.AA MAST 700-807 35 1.2e-20 62.93 In-house 223-334 (334) Show / Hide
Range on Protein: 700-807
Range on HMM: 223-334/334
Sequence Identity: 35% (42 aa)

SLVGTGNYMAPEVIAKTG-HNQSCDWWSTGVILYEMVFGRVPFHDDTPGGTQHRIKNWR---NFLDFTYCGN----LSKECLMMIQQLI-CDASSRLGSH
...||  |.||||| ..| |... |||| |.|.||   | .|| ||||  .   |.| .   . . ..  .|    .|.|    |..|  .| . |||. 
QCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

-GKDVAERTAQVKNHPWF
 |       ..||.|| |
NG------ADEVKQHPFF

Kinase T20F10.1.AA Pkinase 698-807 26 5.1e-18 64.79 Pfam 168-293 (293) Show / Hide
Range on Protein: 698-807
Range on HMM: 168-293/293
Sequence Identity: 26% (36 aa)

AHSLVGTGNYMAPEVIA-KTGHNQSCDWWSTGVILYEMVFGRVPFHDD----TPGGTQHRIKNWRNFLDFTYCG--------------------NLSKEC
.....|| .|||||||   ... ...|.|| |.|||||..|| || ..    .    ...|.. .       .                     |.|.||
MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC

LMMIQQLIC-DASSRLGSHGKDVAERTAQVKNHPWF
.  |  ..| | ..|..          .|...||||
KDFIKWCLCKDPKKRPT---------AEQILQHPWF

Kinase T20F10.1.AA PKA 703-746 46 4.7e-15 56.35 In-house 160-206 (263) Show / Hide
Range on Protein: 703-746
Range on HMM: 160-206/263
Sequence Identity: 46% (22 aa)

GTGNYMAPEVIAKT-GHNQSCDWWSTGVILYEMVFGRVPFHDD--TP
||  |.|||.|  . ||. | |||. |.. |||..|  || |.  .|
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDP

Kinase T20F10.1.AA TyrKc 502-780 20 1.2e-09 -66.88 SMART 1-280 (280) Show / Hide
Range on Protein: 502-780
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

FTVISHIGVGAFGKVSLVRKNDTRKVYAMKSLEKADVIMKQQAAHVKAERDILAEA--DSPWIVRLFFSFQDD-------ACLYFIMEYVPGGDMMTLLI
 | .  .| ||||.| . . .  ..| | |.| .         .    |  |. .   . | ||||.    ..         |. .|||.|.||    | 
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

QKGI-FEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLCTGLRWTHDRRYYGPE------NDHHRVDSFSLPPEVAAIDKSVK
 ..  .  .    .    ||  || |  ..|||||   |.|..  ...| .||||.         |. . .       |  |. .           |. |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS---------RDIYDDDQQGESKDYYRKKE----------HKGGK

-VLNVRQQTRRITAHSLVGTGNYMAPEVIAKTGHNQSCDWWSTGVILYEMV-FGRVPFHD---------DTPGGTQHRIKNWRNFL--------DFTYCG
 .| .|                 ||||.| .   .   | || || ..|.  .|  |  .         .     ...    .             .   
TMLPIR----------------WMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY

NLSKECLMM----------IQQLI
.. |.| .           | ...
QIMKQCWHEDPEDRPTFSEIHECF

Kinase T20F10.1.AA Pkinase_Tyr 575-647 31 2.3e-09 32.34 Pfam 82-158 (270) Show / Hide
Range on Protein: 575-647
Range on HMM: 82-158/270
Sequence Identity: 31% (24 aa)

LYFIMEYVPGGDMMTLLIQ----KGIFEEDLARFYIAELACAIEYVHNVGFIHRDLKPDNILIDQHGHIKLTDFGLC
.| .|||.|.||. . | .    |. .       . .. |.. || .. ..|||||   |.|..  ...| .||||.
IYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

Kinase T20F10.1.AA S_TK_X 808-866 22 2e-06 28.88 SMART 1-79 (79) Show / Hide
Range on Protein: 808-866
Range on HMM: 1-79/79
Sequence Identity: 22% (18 aa)

RGIDWVNLRK--LRADYIYIPRVT----HDEDTSNFE-TFQDNDRADKPN----VRGLHNPA---------FYEFTYRH
||||| .|..   .    ..|...    ...|||||.  | ...  ..|     ... ....         | .|||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase T20F10.1.AA Pkinase_C 827-868 21 1.1e-05 23.27 Pfam 1-46 (46) Show / Hide
Range on Protein: 827-868
Range on HMM: 1-46/46
Sequence Identity: 21% (11 aa)

RVTHDEDTSNFET----------FQDNDRADKPNVRGLHNPAFYEFTYRHFF
.|....|||||..          .      |..  .  .. .|  |||....
QVKSPTDTSNFDPEFTDEPPMDTP-----PDWR-MSSGDQEPFRGFTYVNPD

Kinase T20F10.1.AA Akt 786-807 45 0.001175 7.47 In-house 247-264 (264) Show / Hide
Range on Protein: 786-807
Range on HMM: 247-264/264
Sequence Identity: 45% (10 aa)

RLGSHGKDVAERTAQVKNHPWF
|||.. .|. |    .|.||||
RLGGGPNDAQE----IKRHPWF

Kinase T20F10.1.AA PKA 782-807 30 0.001395 13.1 In-house 242-263 (263) Show / Hide
Range on Protein: 782-807
Range on HMM: 242-263/263
Sequence Identity: 30% (8 aa)

DASSRLGSHGKDVAERTAQVKNHPWF
| . |.|..      .. ..|||.||
DLTKRYGNMKN----GVNDIKNHKWF

Kinase T20F10.1.AA Pkinase_Tyr 502-516 46 1.418051 2.57 Pfam 1-15 (270) Show / Hide
Range on Protein: 502-516
Range on HMM: 1-15/270
Sequence Identity: 46% (7 aa)

FTVISHIGVGAFGKV
 | .  .| ||||.|
ITFGKKLGEGAFGEV