Gene T05E8.2 (Nematode worm)

T05E8.2

Species: Nematode worm
Alias: aSWK216, T05E8.2, CE13243
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:0.06, WormBase Physical Map location: I: 5469630-5463455

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
T05E8.2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 291 Kinase domain by global Sugen HMM Fasta, JSON
T05E8.2.AA Protein Genbank 473 None Fasta, JSON

Protein domain

Protein domains of T05E8.2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase T05E8.2.AA Haspin 166-393 25 1.5e-93 317.14 In-house 1-264 (264) Show / Hide 
Range on Protein: 166-393
Range on HMM: 1-264/264
Sequence Identity: 25% (67 aa)

AKSKLGFGQTGDVLQIERSGRSEALKMCRLAGPDT-------------VQNAYKELKIWQSIKAIQMA--TPNFPDFYGSCVIKEVQGNVEKLLRHAGKV
...|.|.|..|.| .....|.....|.... ....             ...|..|..|..........  .||||.|.|.||...|.|...|.|... ..
NCKKIGEGCYGEVFSVTWNGKEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKKLNKMWDH

YCG--------------------IFSEICKKRLDNIRRNSLTCSESVAIMQQLVLTLAIAKDRILLNHRDLFGGNVLIK-VTGKTNLHYTHNGVKITLMR
||                     ...| ....|||.|....||.....||.|||....||||.. ..|.||. |||||| .|.|..||||..|..|....
YCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDGKTIKIKS

KAMLCILLILDKVQLAVKVVKLPKNPKTDYTLEFFLWKTSIGIGFSIPKNRCTYNFILIAQKLR
...........|.... .  | ....|.|.|.....|...........||.....|...|....
HGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK
S_TKc T05E8.2.AA S_TKc 164-413 13 0.000773 -120.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 164-413
Range on HMM: 1-231/231
Sequence Identity: 13% (41 aa)

IEAKSKLGFGQTGDVLQIER--SGRSEALKMCRLAGPDTVQNAYKELKIWQSIKAIQMATPNFPDFYGSCVIKEVQGNVEKLLRHAGKVYCGIFSEICKK
 |   |.| |  | | .     .||  |.|. .       .....|..| ..        ||   .|....                  .  .. | |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK------HHPNIVKLYDVFQD----------------DHLYMVMEYCDG

---RLDNIRRNS--------LTCSESVAIMQQLVLTLAIAKDRILLNHRDLFGGNVLIKVTGKTNLHYTHNGVKIT------------------------
    |  . ..         ..  .   .|.|... |.   ..    ||||   |.|.              .||.                        
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE-----------HIKICDFGLARQLTTFCGTPWYMAPEVLG

LMR-KA-----------MLC-ILLILDKVQLAVKVVKLPKNPKTDYTLEFFLWKTSIGIGFSIPKNRCTYNFILIAQKLRANERKVEKSTAQLLW-D---
  . |.           |||   .    .|.  |...                             .   .||    .   ..|    .  ..|  .   
YGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------------------SPEAKDFIRKCLQKDPEKR---PTA-EALQDEWDI

--TPRF
   | |
KCHPWF