Gene spe-8 (Nematode worm)

spe-8

Species: Nematode worm
Alias: spe-8, CE29331, aSWK363, F53G12.6
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: I:-15.4775, WormBase Physical Map location: I: 118109-120870

Classification

Group: TK
Family: Fer

Sequence

Name Sequence Type Origin Length Description Download
spe-8.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 258 Kinase domain by global Sugen HMM Fasta, JSON
spe-8.AA Protein Genbank 512 None Fasta, JSON

Protein domain

Protein domains of spe-8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH2 spe-8.AA SH2 112-194 32 5e-26 93.71 SMART 1-87 (87) Show / Hide 
Range on Protein: 112-194
Range on HMM: 1-87/87
Sequence Identity: 32% (29 aa)

FPFYHGFMGRNECEAMLSNH----GDFLIRMTEIGKRVAYVISIKWKYQNIHVLVKRTKTKKLYWTK--KYAFKSICELIAYHKRNHKP
 |.|||.. | |.|..| |.    ||||.|  |  .. .||.|..|| .. | ...|....| | .   .. | |. ||......|  .
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES-NPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 spe-8.AA SH2 114-188 29 1.6e-17 53.29 Pfam 1-81 (81) Show / Hide 
Range on Protein: 114-188
Range on HMM: 1-81/81
Sequence Identity: 29% (25 aa)

FYHGFMGRNECEAMLSN----HGDFLIRMTE--IGKRVAYVISIKWKY---QNIHVLVKRTKTKKLYWTKKYAFKSICELIAYH
.|||.. |.| | .| |    .|.||.|  |  .|    |..| ...    .. |  ..||.....| | .  | |. ||. ..
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase spe-8.AA Fer 217-476 39 1.9e-130 439.65 In-house 1-283 (283) Show / Hide 
Range on Protein: 217-476
Range on HMM: 1-283/283
Sequence Identity: 39% (113 aa)

VTLNKKLGEGQFGEVHKG------SLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLT-LSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDAL
|||.|||||| ||||.||       ......  .| |.||......... ... |..||..|.. ..||||.||||||....|||||||||.| ||...|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

LSKEEK-VSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNS-KKILK--ISDFGLSVK----GVAIKER-KGGCLPVKYMAPETLKKGLYSTASD
  ...| ||  .|| ....||||..|||.|..|||||||||||.   |  .|  |||||.|..    |.. |.. |  ..|....||||...|.||...|
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

IYSYGALMYEVYTDGKTPFET------CGLRGNELRKAIIGKRISLAVEVELPVFIANIFE-QSRQYETEDRISSKQIIQIFK
..|.| ...|..|.|..|...      ..   ...||.|| |.  .  . . |..|..| . |  |...|||.. |.|.|..|
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase spe-8.AA TK 217-475 20 2.6e-85 285.86 In-house 1-486 (486) Show / Hide 
Range on Protein: 217-475
Range on HMM: 1-486/486
Sequence Identity: 20% (101 aa)

VTLNKKLGEGQFG---EVHKGSLKTSV---------------------FAAPVTVAVKTLHQNH-LSANEKIL-----------FLREANVMLTLS----
.|| |||||||||   ||.|| ...                         ....||||.|.  .  |..|...           ||.||..|  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNVIKFYGVCTMK------------EPIMIVMEFCDGKS----LEDALLSKEEK--------------------------------------------
 |||....||||| .            ||.|||||.... .    | | | .. .|                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VSAEDKILYLFHAACGIDYLHGK------QVIHRDIAARNCLLNSKKI-----------LKISDFGLSV
                               .. .... . . .|||  ||| |      ...|||.||||||......            ||.||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

KG---VAIKERK--------------------------------GGCLPVKYMAPETLK---------KGLYSTASDIYSYGALMYEVYTDG-KTPFETC
.|    | .  .                                || ||...||||.|.         .| ..|.||..|.| ||.|..| | ... .  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

GLRG-------NELRKAII-------------GKRISLAVEVELP--------------VFIANIFEQSRQYETEDRISSKQIIQIF
  ..        |. . .              | |  ..  .  |               ... .  |  .|. ||| . .|. . .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase spe-8.AA TyrKc 217-475 33 1.2e-84 288.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 217-475
Range on HMM: 1-280/280
Sequence Identity: 33% (99 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTL--SHPNVIKFYGVCTMK-------EPIMIVMEFCDGKSLED
.||.||||||.||||.|| .|       ..||||.|. ..     .  |.|||..|  |  .|||....||||| .       ||.|||||.... .| |
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

ALLSKEEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKG----------VAIKERK--GGC--LPVKYMAPETLKKG
 | ....|.. .|.. . . .||| .||| |..||||.||||||...... |||||||| ..            .. ..  ||   ||.. ||||....|
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

LYSTASDIYSYGALMYEVYTDGKTPFET-CG--LRGNELRKAIIGKRISLAVEV-------ELPVFIANIFEQSRQYETEDRISSKQIIQIF
 ..|.||..|.| .|.|..|.|..| .      .   |... .   .     .        . |  . .| .|  ... ||| . ..|...|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase spe-8.AA Pkinase_Tyr 217-420 39 9e-83 280.95 Pfam 1-217 (270) Show / Hide 
Range on Protein: 217-420
Range on HMM: 1-217/270
Sequence Identity: 39% (87 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANE--KILFLREANVMLTL-SHPNVIKFYGVCT-MKEP--IMIVMEFCDGKSLEDALL
.|..||||||.||||.|| .| .     ..||||.|  .. .  .  .  |.|||..| .| .|||....|||||  .||  |.||||.. . .| | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SK---EEKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKG-----VAIKERKGGCLPVKYMAPETLKKGLYSTASDIY
..   ..... .|.. . .  |.| .||. |. ||||.||||||...... ||.||||.          .. |.|| ||.| |||| .. | ..|.||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGALMYEVYTDGKTP-FE
|.| ||.|..| |..| ..
SFGVLMWEIFTYGEQPTYP
Kinase spe-8.AA UTK 217-420 29 1.2e-59 202.78 In-house 1-242 (296) Show / Hide 
Range on Protein: 217-420
Range on HMM: 1-242/296
Sequence Identity: 29% (72 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPV-TVAVKTLHQNHLSANEKI---LFLREAN---VMLTLS-HPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDA
| | ..||.|.||||||.....    ...  ||||..   . .  |.     |..||.   .|  .. ||||....||||  ||.|||.|.. . .| . 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LLSKEE-------KVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSK-------KILKISDFG---LS--VK---------GVAIKERKG-GC
| .  .        .. .... .  . |.|  |||.....|||.||||||...         . ||.|||   .|  |.         .     . . . 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKYMAPETLKKG-LYSTASDIYSYGALMYEVYTDGKTPFE
.|.. |||| | ..  ..|.||..|.| ...|..| |..|..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYP
Kinase spe-8.AA TK-Unique 217-419 32 2e-57 196.54 In-house 1-240 (294) Show / Hide 
Range on Protein: 217-419
Range on HMM: 1-240/294
Sequence Identity: 32% (79 aa)

VTLNKKLGEGQFGEVHKGSLKT--SVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLS-HPNVIKFYGVCTMK-EPIMIVMEFCDGKSLEDALLSK
.......|||.||.|..| ...   .. ... ||||.|. | ..  .|  ||.|...|  |  |||.....|.|| . || ||.||.| . .|.. | ..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDN-ATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

EEK-------------------------VSAEDKILYLFHAACGIDYLHG--KQVIHRDIAARNCLLNSKKILKISDFGLSV----KGVAIKERKGGCLP
  .                         .| .| . ...  |||  ||..  |...|||..|||.||...|..||.|||..      || ..... | .|
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP

VKYMAPETLK--KGLY-STASDIYSYGALMYEVYTDGKTPF
...|||| ||  .| | .| ||..|.| ||.|. | |..|.
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPY
Kinase spe-8.AA SFK-Src 217-420 38 7.8e-53 154.59 In-house 1-201 (259) Show / Hide 
Range on Protein: 217-420
Range on HMM: 1-201/259
Sequence Identity: 38% (80 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALLS-KEEK
. | ||||.||||.| ||     .      ||||||     ||.|   ||.|| ||  | ||| |. | ||| .||| |. | .   || | | . . . 
IRLEKKLGSGQFGDVWKG-----RWNNTTEVAVKTLKPGAMSAEE---FLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRS

VSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKGVAIKER-----KGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYE
      .      | |  || ..  .||| |||| |     . |. |||.|  ..| ..      .|   |.|  |||  .   .|. ||. |.| ||.|
LRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMS-RVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMME

VYTDGKTPFE
. | |  |..
IVTYGRIPYP
Kinase spe-8.AA Src 217-420 35 1.9e-51 173.01 In-house 1-202 (255) Show / Hide 
Range on Protein: 217-420
Range on HMM: 1-202/255
Sequence Identity: 35% (76 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALL--SKEE
..| .|||.|||||| .|     ..   . |||||| . ..| .    ||.||..| .|.|..... | ||. .||| || |.    || | |   ... 
IKLCRKLGQGQFGEVWMG-----YWNGNTKVAVKTLKPGTMSPEA---FLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR

KVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKGVAIK--E-----RKGGCLPVKYMAPETLKKGLYSTASDIYSYGAL
... .. |    . | | .||  ...|||| |||| | . . . |. ||||      ||  .     |.|  .|.| .||| .  | ... ||  |.| |
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR---LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGIL

MYEVYTDGKTPFE
..|. | |..| .
LTEIVTYGRVPYP
Kinase spe-8.AA TKL 223-475 19 9.6e-49 168.25 In-house 1-364 (364) Show / Hide 
Range on Protein: 223-475
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGEGQFGEVHKGSLK-TSVFAAP----VTVAVKTLHQNHLSANEK-------------------------ILFLREANVMLTLSHPNVIKFYGVCTMKEP
.|.| ||||.|| .. ... . |     .||||...... . ..|                           . .|...|. |.|||...|.|.|.  ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------IMIVMEFCDGKSLEDALLSKEEKVSAEDKILYLFHAACGIDYLHG--------KQVIHRDIAARNCLLNSKKI--------------
             ..||||.|.| ||.. |.        . ..     .|.|..|||         ...||||.  .|.|....                
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

LKISDFGLSVKGVAIKE--------------------RKGGCLPVKYMAPETLK----------------KGLYSTASDIYSYGALMYEVYTDGKTPFET
.||.|||||      ..                    .   |    .|||| |.                .. ||...|.||.| ...|..| ...|.. 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILT-RCRPYYD

CGLRGNELR-------KAII--GKRISLA----------VEVELPVFIANIFEQSRQYETEDRISSKQIIQIF
 . .  ...       . ..  |.|  .            .   |  .... ..  ... |.| | ..|....
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase spe-8.AA S_TKc 217-476 24 1.7e-46 161.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 217-476
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDG--KSLEDALLSKEE
 .. .|.|.| ||.|.|.  |         ||.| ..         . ..|| ...    |||..|.|.|.   . . .|||.|||   .| | . ..  
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

K-----VSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVKGVAIKERKGGCLPVKYMAPETLKKGLYST-ASDIYSYGALM
.      .  .   |.   .|...|.| ...||||.   | ||..   .||.||||. .       .  |    ||||| |    |.. ..|..| | ..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YEVYTDGKTPFETCGLRGNELRKAIIGKRISLAVEVELPVFIANIFEQSRQYETEDRISSKQIIQ--------IFK
|| .. |..||.           . . |.|        | ..  . ..  |.. |.|..  .. |         . 
YEMLC-GYPPFP---------QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase spe-8.AA Eph 217-419 35 3.1e-45 149.81 In-house 1-211 (264) Show / Hide 
Range on Protein: 217-419
Range on HMM: 1-211/264
Sequence Identity: 35% (76 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPV---TVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALLSKE
... | .|.|.|||| .| ||..  .. |   .||.||| . . .. ... ||.|| .|   .|||.|.  || |  .|.||| |. .  || . |  ..
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGY-TEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD

EKVSAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLSVK-----G-VAIKERKGGCLPVKYMAPETLKKGLYSTASDIYSYGAL
.....   .  |   | |  ||     .||| |||| |.||. . |.||||||       .  |  . .||  |..  |||..  . ...|||. ||| .
GQFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIV

MYEVYTDGKTPF
| || . |  |.
MWEVMSYGERPY
Kinase spe-8.AA Pkinase 217-419 28 8e-43 152.5 Pfam 1-212 (293) Show / Hide 
Range on Protein: 217-419
Range on HMM: 1-212/293
Sequence Identity: 28% (62 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLR--EANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGK----SLEDALL
 .. .|.|.| ||.| |.  | .      .||||..   | . ....  .|  |. .|. |.|||....|.... |  | .|||.|.|     .| | . 
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

-SKEEKV--SAEDKILYLFHAACGIDYLHGKQVIHRDIAARNCLLNSKKIL----KISDFGLSVK--GVAIKERKGGCLPVKYMAPETLK-KGLYSTASD
 ... ..  | .. . |.   ..|..|.| . .||||.   |.|....  .    ||.||||. .         .. |    ||||| ..    |....|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IYSYGALMYEVYTDGKTPF
..|.| ..||... |..||
MWSCGCILYEMLC-GRPPF
Kinase spe-8.AA Tec 217-366 36 1.6e-36 125.15 In-house 1-144 (254) Show / Hide 
Range on Protein: 217-366
Range on HMM: 1-144/254
Sequence Identity: 36% (55 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQNHLSANEKILFLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEFCDGKSLEDALLSKEEKV
 |. | || |||| || | .. . .     ||.|..     |  .   |. || ||  ||||. ...||||. . || || |.    .| . | ... . 
LTFMKELGSGQFGVVHLGKWRHQYD-----VAIKMIKEGSMSEED---FIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHF

SAED-KILYLFHAAC-GIDYLHGKQVIHRDIAARNCLLNSKKILKISDFGLS
...    |..    | |  ||  ...|||| |||||| ..... |.||||..
QKNMAILLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMT
Kinase spe-8.AA Src-Unclassified 217-299 36 4.2e-23 76.03 In-house 1-86 (284) Show / Hide 
Range on Protein: 217-299
Range on HMM: 1-86/284
Sequence Identity: 36% (34 aa)

VTLNKKLGEGQFGEVHKGSLKTSVFAAPVTVAVKTLHQN---HLSANEKIL------FLREANVMLTLSHPNVIKFYGVCTMKEPIMIVMEF
| | .||| |||||| .|  . .     | |||||.       .| .|  |      | .||..|  ..|.|... |.||.  ||. |. |.
VHLLRKLGRGQFGEVWYGKWRGK-----VDVAVKTMRPGHSETMS-PEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEY
Kinase spe-8.AA Src-Unclassified 329-418 40 7.9e-23 75.05 In-house 129-227 (284) Show / Hide 
Range on Protein: 329-418
Range on HMM: 129-227/284
Sequence Identity: 40% (40 aa)

ACGIDYLHGKQVIHRDIAARNCLLNSKK-----ILKISDFGLS-VKGVAIKE---RKGGCLPVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTP
| | .||  |. .||| |||| |   .      . |. ||||   | ..  .   |.|  .|.| ||||    |  |. ||. ||| | .|. | |.||
ASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFIYGNFSIKSDVWSYGILLWEIMTKGQTP
Kinase spe-8.AA Tec 381-420 45 2.7e-10 32.24 In-house 161-200 (254) Show / Hide 
Range on Protein: 381-420
Range on HMM: 161-200/254
Sequence Identity: 45% (18 aa)

PVKYMAPETLKKGLYSTASDIYSYGALMYEVYTDGKTPFE
|||  .|| ..   ||  ||. ..| || ||.. || |.|
PVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE