Gene sma-6 (Nematode worm)

sma-6

Species: Nematode worm
Alias: aSWK426, C32D5.2x=(vsss..vpa), C32D5.2, sma-6, CE01842
External Links: Wormbase Link ,
Annotation: WormBase Genetic Map location: II:-0.390025, WormBase Physical Map location: II: 6324425-6327295

Classification

Group: TKL
Family: STKR
Subfamily: STKR1

Sequence

Name Sequence Type Origin Length Description Download
sma-6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 340 Kinase domain by global Sugen HMM Fasta, JSON
sma-6.AA Protein Genbank 636 None Fasta, JSON

Protein domain

Protein domains of sma-6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Activin_recp sma-6.AA Activin_recp 66-158 23 6.4e-24 81.0 Pfam 1-121 (121) Show / Hide 
Range on Protein: 66-158
Range on HMM: 1-121/121
Sequence Identity: 23% (29 aa)

NRCY-CNYDQSI----CG--NN------MTCVKQD--------GAACYHAVEEVYNKA-EKRMETLHKWGCATLERGSGASH-LTCNS----WRAAHHSP
..|| ||.....    |.  .|       || .          ...||...|.....   . ... |  || .|.......| ..| |       .|...
LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG

KSIGC-CYEGNYCNKNLIPPA
... | |.|..|||.|| ||.
HNHECWCCETDYCNRNLTPPP
Kinase sma-6.AA Type1 265-602 43 3.5e-227 622.67 In-house 1-290 (290) Show / Hide 
Range on Protein: 265-602
Range on HMM: 1-290/290
Sequence Identity: 43% (148 aa)

LTIIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSDYLCREETLTTDEA
...|..||.||||||... .||..||||.|...||.||..|...|||.|..|||||.|.|||.... .|.|...|||||||.|||.|||. ..||.|...
IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDN-GSWTQLWLITDYHEHGSLYDYLN-RHTLDTQQM

LRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQND-KILPEKFNVQVGTKRYMAPELISNKLNPKDFSQFKMAD
|||..||.||..|||....|| .|.||.|||||||||||.||....|||||||||.|.|.| .......|..||||||||||......|...|...||||
LRLAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMAD

IYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPP
|||..|||||.|.|.||..                                               .......|....|.|||.|..|..|.|||..||.
IYSFGLVMWEIARRCEVGG-----------------------------------------------IVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPN

PDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKKEM
.. .|...|......|||...|...||.||.||..||..
IPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL
Kinase sma-6.AA STKR 265-602 40 2e-179 584.21 In-house 1-312 (312) Show / Hide 
Range on Protein: 265-602
Range on HMM: 1-312/312
Sequence Identity: 40% (143 aa)

LTIIKTIGQGRYGEVRKALYRG----SYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSDYLCREETLT
...|..||.|||||| |. .||     .||||.|...||.||..|...||| |..|||||||.|||....|.|.|...|||.|||.|||.|||. ..|..
IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLK-RHTID

TDEALRLIHSCICGIEHLHAAVH--GTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQND-KILPEK-------FNVQVGTKRYMAPELISNK
..|..|..||..||. |||. ..  ||....|| |||||||||||.||... |||||.|||.|...| . .. .       .| |||||||||||.....
WHEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGA

LNPKDFSQ-FKMADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFD
.|...| . ||..|.|.|.|||||.|.|.......  |                                       .. .......||. .|.|.|.|.
MNFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPD--L---------------------------------------VDQIVPEYQMPFYDWVPNHPSFE

EMNDVICVRRIRPPPDLAWK-NVPALNELSKLMEDSWHSIPHFRHSALKLKKEM
.|..|.|..| ||. . .|| | ||.....|.||. |.  |..|..||..||.|
DMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPEARLTALCVKKTM
Kinase sma-6.AA TKL 271-602 20 7.7e-82 278.19 In-house 1-364 (364) Show / Hide 
Range on Protein: 271-602
Range on HMM: 1-364/364
Sequence Identity: 20% (89 aa)

IGQGRYGEVRKALYRG----------SYVAVKTFYTTD-------------------------EDSWKNERDVYQTNM---INHENILQFVAADI-----
||.|..||| |. .||            ||||.| ...                         | || ... .....|   ..|.||.||.....     
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WSEE--DSMTKMLLITDYHELGSLSDYLCREETLTTDEALRLIHSCICGIEHLHAAVH--GTGSFRKPEIAHRDIKSKNIIVKRPNV------------
 ....  .. ... ....|.. ||| .||        .  .|..... .|...||.     .|    || |.|||.||||| |.. .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCT----KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--CCIADLGLALRYQNDKILPE----------------KFNVQVGTKRYMAPELISNKLNPKD----------FSQFKMADIYSMALVMWEVAIRVEVNT
  |.|.|.||. . ....                    . . |.||.|.||||.. ...| ..          |. .. .|.||...|.||.. | .   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

CEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPPPDLAWKN-------VPALN
                                                   . .|.. .. .|| |.||  ..|... |||..  |.|        ... 
-------------------------------------------------PYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPP

ELSKLMEDSWHSIPHFRHSALKLKKEM
...|||.| |.. |. | |.....|..
SMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase sma-6.AA Type2 265-477 39 2.2e-73 241.59 In-house 1-232 (315) Show / Hide 
Range on Protein: 265-477
Range on HMM: 1-232/315
Sequence Identity: 39% (93 aa)

LTIIKTIGQGRYGEVRKALYRGS-----YVAVKTFYTTDEDSWKNERDVYQTN-MINHENILQFVAADIW--SEEDSMTKMLLITDYHELGSLSDYLCRE
.. .  ||.||.|.| || . .      .|||| |   |  ||.||.|.|..  .  |||||||..|.    . .|     .|.|..|. ||| ||| ..
IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYL-KQ

ETLTTDEALRLIHSCICGIEHLHAAVH-GTG-SFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQNDKIL-------PEKFN--VQVGTKRYMAPE
 |..  |..|...| . |. |||. .  ...  . || ||||||||||. ||    |||||.|||.|.. .|         |.      ||||.||||||
HTIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPE

LISNKLNPKD-FSQFKMADIYSMALVMWEVAIR
.   ..| .|  . || .|.|.|.||.||.. |
VLEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSR
Kinase sma-6.AA Pkinase 265-564 19 2.9e-41 146.99 Pfam 1-236 (293) Show / Hide 
Range on Protein: 265-564
Range on HMM: 1-236/293
Sequence Identity: 19% (62 aa)

LTIIKTIGQGRYGEVRKALYRGSY--VAVKTFYTTDEDSWKNER-----DVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELG----SLSDYL
..|...||.| .|.|.|.  .|.   ||||..   .|.|||...      ..  ...||.||...  .         ... ....|.| |    .|.||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMDLFDYI

C--REETL--TTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVC----CIADLGLALRYQNDKILPEKFNVQVGTKRYMAPE
   |. ..  . .|. . .   ..|.|..|.            | |||.|. || ... ...    .|.| |||  ..      . ... .|| .|||||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSM----------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPE

LISNKLNPKDFSQFKMADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHND
.|      ..    . .|..|. ....|.. .                                                          |||.| . ..
VIR-----GGQYYGPKVDMWSCGCILYEMLCGR---------------------------------------------------------PPFPGHC-WH

PNFDEMNDVICVRRIRPPP
.| .... .|| .. .|..
DN-HDQMQMICRIMGPPLH
Kinase sma-6.AA TKL-Unique 267-475 26 1.2e-24 84.01 In-house 1-222 (290) Show / Hide 
Range on Protein: 267-475
Range on HMM: 1-222/290
Sequence Identity: 26% (63 aa)

IIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERD-----VYQTNMIN-HENILQFVAADIWSEED---SMTKMLLITDYHELGSLSDYLC---
....||.| ||.| |. .||. ||.|.|    ||| . ...     |   .... |.||...... .    |   .  .| ....| ..||| |.|    
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCM----DHQVYPPNMCIVMEYCPGGSLYDVLHQNN

-------REETLTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRP-----NVCCIADLGLALRYQNDKILPEKFN--------V
       .. .|.    ..... .  | ..||        ...| |.|||.||.|. | .      .   |.| ||.    |.||. ...|        .
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLH--------HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLS--KFNSKINKMTNNEHKGTRNQT

QVGTKRYMAPELISNKLNPKDFSQFKMADIYSMALVMWEVA
 .|. |.||||....    ...|.   .|.|| . |.|| |
RCGSFRWMAPEVLRMNF--CQYSE--KSDVYSFGIVLWEIA
Kinase sma-6.AA Ciliate-E2-Unclassified 266-467 18 7.9e-22 72.51 In-house 2-256 (352) Show / Hide 
Range on Protein: 266-467
Range on HMM: 2-256/352
Sequence Identity: 18% (51 aa)

TIIKTIGQGRYGEVRKALYRGSY-------------VAVKTFYTTDEDSWKNERDVYQTNMINHEN----ILQ---------FVAADIWSEEDSMTKMLL
.|||.|||| .|.|.|.  .  .             ...|   . | . . ..  . . .. .| .    |.|         |.  ... ..|   .. .
KIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ-NIYI

ITDYHELGSLSDYLCREET-----------------LTTDEAL-----RLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPN---VCCIA
...| | |.|..|..  ..                 .|  .|.     ...   ..|.|.||          .  | |||||  ||...  .    ..|.
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH--------HKN-NIIHRDIKPENILFDNNGKNYYIKII

DLGLALRYQND------------KILPEKFNVQVGTKRYM----APELISN-KLNPKDFSQFKMADIYSM
|.|.. .||..             . ..... ..|| .||    |||.. . . . . .   ...||.|.
DFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSL
Kinase sma-6.AA Ciliate-E2 265-467 19 1.1e-21 71.16 In-house 1-282 (365) Show / Hide 
Range on Protein: 265-467
Range on HMM: 1-282/365
Sequence Identity: 19% (58 aa)

LTIIKTIGQGRYGEVRKA-------LY------------------RGSYVAVKTFYTTDEDSWKNERDVY-QTN-------------MINHENILQFVAA
  .|| |||| .| |.|.       ..                   ....|.|..   .  ..|.| ... . |              .|| ||...   
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKM---

DIWSEED-SMTKMLLITDYHELGSLSDYL------CREE-----TLTTDEALRLIHSCIC---------------GIEHLHAAVHGTGSFRKPEIAHRDI
 ... .. . ... |...| . |.| ||.      . .|      .|  |.....   .                ..|.||          |  | ||||
-YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLH---------SKNNIIHRDI

KSKNIIVKRPNVCCIADLGLALRYQND----------KILPEKF-------------------NVQVGTKRYMAPELISNKL---NPKDFSQF----KMA
|  ||..     ..|.|.||. .|..|          |.... .                   | ..||  ||||| ...|    .    ...    ...
KPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----QKQKGYDYKC

DIYSM
||.|.
DIWSL
Kinase sma-6.AA MLK 265-474 22 1.4e-18 61.18 In-house 1-229 (291) Show / Hide 
Range on Protein: 265-474
Range on HMM: 1-229/291
Sequence Identity: 22% (57 aa)

LTIIKTIGQGRYGEVRKALYRGSY-----VAVKTFY-------TTDEDSWKNERDVYQTNMINHEN----ILQFVAADIWSEEDSMTK-MLLITDYHELG
... . || | .|.| |. .|.       |||| .         |.. .|. |..... ....|.|    | ||... .     . ..  .... | | |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCL-----QPPCHFCIVMEYCEGG

SLSDYLCREET--------------LTTDEALRLIHSCICGIEHLHA-AVHGTGSFRKPEIAHRDIKSKNIIVKR------PNVCCIADLGLALRYQND-
||...|  ...               . | |..  . |  |.. ||. |..         | |||.||.|| . .        .. |.| |..   ..  
SLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPK--------PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC

--KILPEKFNVQVGTKRYMAPELI----SNKLNPKDFSQFKMADIYSMALVMWEV
  .        . || ..|||| |    ..| . |       .|..| ..|.||.
TNMM------SNAGTYAWMAPEVIQQFRCEKYSEK-------CDVWSWGVVLWEM
Kinase sma-6.AA S_TKc 265-606 13 6.4e-16 56.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 265-606
Range on HMM: 1-231/231
Sequence Identity: 13% (49 aa)

LTIIKTIGQGRYGEVRKALYRG--SYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHEL--GSLSDYLCREET--
 .|...||.| .|.|.|.  ..   .||.|       .. ..|... .    .|.|| ..  .         ... ....| .   |.| ||...  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQNDKILPEKFNVQVGTKRYMAPELISNKLNPK
    ..  .| ....  .|..|..|   .         | |||.|  || . .  .  |.| ||| ..          . ..||  |||||..       
LRFPFPE-HARFYMYQICCALEYCHSH-G---------IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-------

DFSQFKM--ADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMN
   ..    .|..|   ...| . .      .. .. .                                                              
---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------------------------------------------------------

DVICVRRIRPPPDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKK-----EMAELI
                       |.  ...  ..  |  | .| .. .      . . .
---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase sma-6.AA TyrKc 265-602 16 5.8e-12 -29.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 265-602
Range on HMM: 1-280/280
Sequence Identity: 16% (64 aa)

LTIIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERDVYQ-----TNM-INHENILQFVAADIWSEEDSM---TKMLLITDYHELGSLSDYL--
.| .|..| | .|||.|. ..   ||||.           ..| ..     ..   .|.||...... . ...        ..... | ..|.| |||  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKDYLRK

CREETLTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQND-------KILPEKF--NVQ-VGTKRYMA
.|.. |.... |   .   || |.||             . |||.   |. |...... |.| ||.    .|       .    |   .   .   | ||
HRPK-LCMKDLLSFCWQIACGMEYLHSK----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PELISNKLNPKDFSQF-KMADIYSMALVMWEVA-------IRVEV--NTCEEVLTVDETS-----PDH----SASSGIGESVSSSGNISRMHLQKTNVEG
|| |       ... |    |..|   .|||.          ..    . .||.   ..      |..    |                           
PECI-------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------

HSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPPPDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKKEM
                                              | .  |. ..|.. ||  |. | .   .....
-------------------------------------------F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
GS sma-6.AA GS 238-265 45 2.9e-11 44.68 SMART 1-31 (31) Show / Hide 
Range on Protein: 238-265
Range on HMM: 1-31/31
Sequence Identity: 45% (14 aa)

MESKSMLED---SGSGSGQAALIQRTVRQDL
.....|.||   ||||||...|.||||....
KTMHDMMEDTCTSGSGSGLPLLVQRTVARQI
Kinase sma-6.AA CAMK 270-379 13 2.3e-10 28.86 In-house 1-196 (425) Show / Hide 
Range on Protein: 270-379
Range on HMM: 1-196/425
Sequence Identity: 13% (27 aa)

TIGQGRYGEVRKALYR-G-------------SYVAVKTFYTT-------------------------------DEDSWKNERDVYQT-----NMINHENI
|.|.|..|.|...  .                 ||.|   ..                               |... ..| .. ..     |...|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQFVAADI-----------------WSEEDSMTKMLL-ITDYHELG----SLSDYLCRE---------------ETLTTDEALRLIHSCICGIEHLH
...  .                   . . |..  | . |..| . |     | ||...                  .| .|| |...  .......|
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCH
Kinase sma-6.AA STE 393-449 27 3e-10 32.53 In-house 173-236 (359) Show / Hide 
Range on Protein: 393-449
Range on HMM: 173-236/359
Sequence Identity: 27% (20 aa)

IAHRDIKSKNIIVKRPNVCCIADLGLALRYQN---DKILPE------------KFNVQVGTKRYMAPELISN
| |||||. || .     . ..| |.. . ..   .. . .            | |  |||  .|||| |..
IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQ
TGF_beta_GS sma-6.AA TGF_beta_GS 238-263 41 8.1e-10 35.35 Pfam 1-29 (29) Show / Hide 
Range on Protein: 238-263
Range on HMM: 1-29/29
Sequence Identity: 41% (12 aa)

MESKSMLE---DSGSGSGQAALIQRTVRQ
.....|.|   .||||||.. |.|||. .
KTMQDMMEDFCTSGSGSGLPLLVQRTIAR
Kinase sma-6.AA CAMK 393-448 21 1.2e-08 23.23 In-house 200-293 (425) Show / Hide 
Range on Protein: 393-448
Range on HMM: 200-293/425
Sequence Identity: 21% (20 aa)

IAHRDIKSKNIIVKRP-----------------NVCCIADLGLALRYQNDKILP--------------------EKFNVQVGTKRYMA-PELIS
|.|||.|  || .                    |   |.| |.| ... .. .                     .|.. ..||  ||| ||...
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLN
Kinase sma-6.AA Pkinase_Tyr 265-353 22 3.5e-08 28.33 Pfam 1-98 (270) Show / Hide 
Range on Protein: 265-353
Range on HMM: 1-98/270
Sequence Identity: 22% (23 aa)

LTIIKTIGQGRYGEVRKALYR------GSYVAVKTF--YTTDE----DSWKNERDVYQTNMI-NHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSD
.|..|..|.| .|||.|. ..      .  ||||.   ....|    ..  .|  .     . .|.||...... . .....  ...... | ..|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMK--QLGHHPNIVRLYGVCT-DQGEPN-QIYIVMEYMPHGDLLD

YL
||
YL
Kinase sma-6.AA STE 265-353 15 1.5e-07 22.84 In-house 1-128 (359) Show / Hide 
Range on Protein: 265-353
Range on HMM: 1-128/359
Sequence Identity: 15% (20 aa)

LTIIKTIGQGRYGEVRKALYR-----------------GSYVAVKTFYTTDEDS---------------WKNE---RDVYQTNMIN--HENILQFVAADI
...|. ||.| .|.| ||...                 | ..|.|     ....                . .   ...   .  |  |.|| ..  . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

WSE--EDSMTKMLLITDYHELGSLSDYL
     ... ..  ..  | . |||.| .
KEGHNHKNDDELWICMEYMDGGSLDDII
Kinase sma-6.AA Pkinase_Tyr 395-419 48 0.005127 10.84 Pfam 134-158 (270) Show / Hide 
Range on Protein: 395-419
Range on HMM: 134-158/270
Sequence Identity: 48% (12 aa)

HRDIKSKNIIVKRPNVCCIADLGLA
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HRDLAARNCLVTENNVVKICDFGLA
Kinase sma-6.AA Type2 536-585 30 0.183922 0.35 In-house 247-298 (315) Show / Hide 
Range on Protein: 536-585
Range on HMM: 247-298/315
Sequence Identity: 30% (16 aa)

PPFDGIVHND-PNFDEMNDVICVRRIRPPPDLAWKNVPALN-ELSKLMEDSW
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MPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCW