Gene R90.1 (Nematode worm)

R90.1

Species: Nematode worm
Alias: aSWK079, CE06325, R90.1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 12898472-12894125, WormBase Genetic Map location: V:4.76,

Classification

Group: CK1
Family: TTBK

Sequence

Name Sequence Type Origin Length Description Download
R90.1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
R90.1.AA Protein Genbank 776 None Fasta, JSON

Protein domain

Protein domains of R90.1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase R90.1.AA TTBK 20-276 70 1.6e-208 698.99 In-house 1-257 (257) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-257/257
Sequence Identity: 70% (181 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAV
||...|||||||||||||.|..||||.|||||||....|||||||||||..|||..|.|.|.||||||||||.||.|||||||||||..|..||.|||..
WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVESAQQPKQVLKMEVAVLKKLQGCDHVCRFIGCGRNDKFNYMVMQLQGKNLADLRRKQPRGCFSLSTTL

RVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSPRSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTEF
|.|.|||..|..|||.||||||.|||||||||...|.|..|||||||||||.||.||.|.||..||||||||||...||.|.||||.||||||||||.||
RLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEF

LQGQLPWRKIKDKDEVGKMKEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYL
.|||||||||||||.||.|||..|...||..||||.|.|..|.|.|.|.|.|||. .
VQGQLPWRKIKDKDQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI
Kinase R90.1.AA CK1 20-276 32 2.2e-121 409.57 In-house 1-339 (339) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-339/339
Sequence Identity: 32% (112 aa)

WKIKAKIGGGGFG-EIYEA-----TDVQNHH----ERVAIKVESSKATKQ-VLKMEVAVLRRL---------------------QGKKHACKFYGCGRND
||.. |||.|||| .||..     .|..|.     |..|.|||. |. .|  ..||.... ..                     .|..| |... .|..|
WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED

K-FNYLVMSLQGKNLADLRR--EAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRT------------SQTMRNVYMLDFGLAR-QYL
. .||.||.| |.|| |||.    ....|...|.....||.|......|..||.|||.||.||.|||             ....|.|||.|||.|| .|.
DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYR

NA------------KGEIRSPRS---AAGFRG-TVRYAAVTAHKNKEMGRQDDLWSLFYMLTEFLQGQ--LPWRKIKDKDE-----VGKMKEEADLVVLL
.             ....| ||.   ..|||| |.||. . .|..||.|| |||||.|||| |.| |.  |||...||...     |.|||.|     ..
DKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKM

DD------------CPHEMHLFVAHLKVLGYADTPDYVYL
 .            || |.  .. ... | | |.||| ..
STPFFLCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase R90.1.AA TTBKL 20-280 38 3.9e-119 402.09 In-house 1-288 (288) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-288/288
Sequence Identity: 38% (112 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATK--QVLKMEVAVLRRLQ--GKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQC-FN
|.|. .||.||||..|.. |.... .. | |.|. .  .  ...|||| || .||  |..|..|....|.....|..||.| |.|| |||.  | .. |.
WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS

LSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQT---MRNVYMLDFGLARQYLNAKGEI-----------RSPRS---AAGFRGTVRYAAVTA
 .|..|.|||.| .....|..||.||||||.|...| ....    |.|| .|||.||||..  ||            | ||.    |.||||.||. . .
DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM

HKNKEMGRQDDLWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEADLVVLLDD------CPHEMHLFVAHLKVLGYADTPDYVYLESLL
|  || || |||||..||. |.. | |||. ..||.|...||..  . .|  |      || |.  |. ||. | |.|.||| ..  ..
HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF
Kinase R90.1.AA Worm6 20-276 40 1.3e-106 360.53 In-house 1-279 (279) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-279/279
Sequence Identity: 40% (113 aa)

WKIKAKIGGGGFGEIYEATDVQNHHE-RVAIKVES--SKATKQVLKMEVAVLRRLQGKK--HACKFYGCGRNDK--FNYLVMSLQGKNLADLRREAPKQC
||. .||| |||| .|...| ..    ..|.|.|.   .. .|.||||..|| ..  .|  | ||.  .|. |.  |||.|| | ||||.|||...|...
WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK

FNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGR----TSQTMRNVYMLDFGLAR--QYLNAKGEIRSPR-SAAGFRGTVRYAAVTAHKNKEMGR
| ..|. ...|| |..|.. |..||.||||||.||. ||     .  ....||||||..|  .|.| ..|.| ||  |.|||||||||.. .||..|..|
FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACGFRGTVRYAPLACHKGQEQCR

QDDLWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEA--DL-----VVLLDDCPH-EMHLFVAHLKVLGYADTPDYVYL
.||. | |||. |.. |.||||..||.|.|.| |...  ..       ..  ||. |.      .  . | |.||| ..
KDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI
Kinase R90.1.AA CK1 20-274 32 1.7e-57 196.47 In-house 1-271 (271) Show / Hide 
Range on Protein: 20-274
Range on HMM: 1-271/271
Sequence Identity: 32% (89 aa)

WKIKAKIGGGGFGEIYEATDVQNHHER--VAIKVESSKATKQVLKMEVAVLRRLQG------KKHACKFYGCGRN--DKFNYLVMSLQGKNLADLRREAP
 ..  ||| | ||.||..... . .|.  ||||.|..|.  . |. |. ....|||       ..  . | ||..   ..|..||.| |..| ||     
YRVGRKIGQGSFGDIYLGINM-TNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCN

KQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRYAAVTAHKNKEMGRQDD
.. | | | . .. |..  |  .|. .|.|||.|| || |||. .   .||. ||||| .|. .|     | |   .. ||.||| . .|  .| .| ||
RK-FSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD

LWSLFYMLTEFLQGQLPWRKIK--DKDE----VGKMKEEADLVVLLDD-CPHEMHLFVAHLKVLGYADTPDYV
. || |.|  || |.|||  .|   |..     . .|    . .|  . .| |.. .  . . |.....||| 
MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM
Kinase R90.1.AA CK1-Unclassified 20-230 36 1.7e-55 162.24 In-house 1-220 (244) Show / Hide 
Range on Protein: 20-230
Range on HMM: 1-220/244
Sequence Identity: 36% (81 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKK-------HACKFYGCGRNDK--FNYLVMSLQGKNLADLRREAPK
 ... ||| | |||||.....|.. | ||||.|....    |. |. ....||. .       .  | | ||....  .|..||.| |..| ||     .
YRVIEKIGQGSFGEIYKCINMQTN-EEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDL-FNMCN

QCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNA--KGEIRSPRSAAGFRGTVRYAAVTAHKNKEMGRQDD
. |.| |    . |..  |  .|. .|.||| || || ||.. .   .||. ||||.  |. .   |.    |   .. || ||| . ||. .| .| ||
RKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDD

LWSLFYMLTEFLQGQLPWRKIK
| || | |  || |.|||  ||
LESLGYVLIYFLKGSLPWQNIK
Kinase R90.1.AA CK1-D 20-276 34 8.1e-49 168.5 In-house 1-261 (261) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-261/261
Sequence Identity: 34% (92 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAV
..|  |||.| ||.||  |..|.  | ||||.|. |.    |..|  . . .||     .   ||..  .| .|| | |  | ||     .. | | | .
YRIGRKIGSGSFGDIYHGTNIQTNEE-VAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRK-FSLKTVL

RVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTE
 .. |..  |  ||.  |.|||.|| || ||   .    ||..|||||..|  |. .   | |      || |||..  |.  |  | ||| || |.|  
MLADQMICRIEYIHCRNFIHRDIKPDNFLMG-LGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMY

FLQGQLPWRKIKDK------DEVGKMKEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYL
| .| |||  .|        . .   | .  . .| .  |.|   .... . | . | |||.||
FNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase R90.1.AA CK1-A 20-276 32 4.5e-45 156.07 In-house 1-261 (261) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-261/261
Sequence Identity: 32% (87 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAV
...  ||| | ||.|| .  ..|  | ||||.|| ||    |  |  | | |||     .    |..  .| .|| | |  | ||     .. | . | .
YRLVRKIGSGSFGDIYLGINITNGEE-VAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRR-FTMKTVL

RVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTE
 .  |..  |  .|  .|.|||.|| || || .      ....|||||..|  .. ..  | |      ||.|||.. ||   |  | ||. |. |..  
MLADQMIMRIEYVHEKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMY

FLQGQLPWRKIKDKDEVGKM------KEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYL
| .|.|||  .| .    |       |  . . .|    | |. ..... . |.. ..|||.||
FNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase R90.1.AA Dual 20-280 28 6.1e-42 138.76 In-house 1-282 (282) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-282/282
Sequence Identity: 28% (81 aa)

WKIKAKIGGGGFGEIYEATDVQN---HHERVAIKVESSKATK--------QVLKMEVAVLRRLQG---KKHACKF--YGCGRNDKFNYLVMSLQGKNLAD
||.   .| |||...|   .      . . ...|.||.   |        . ..|..| .|..      |.   |  ||    || .|.|||. |  | .
WKVVNLLGSGGFRDVYHVHRFSQVNPKNKCYILKTESEEGEKMMLRLKVEMQVMMKFAEKRKKEKIPGDKCFIEFVDYGKCEQDKCKYWVMSPYGPSLQE

LRREAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLN-AKGEIRSPRSAAGFRGTVRYAAVTAHKNKE
 || .    .. ...  |.|| |  |.  ||||.|||..||.||. |        |||.||...| |.    .. | .|.   . |. |||     . |.
IRRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCG-LGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKD

MGRQDDLWSLFYMLTEFL-QGQ-LPWRKIKDKDEVGKMKEE---ADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYLESLL
 || ||| .  ||.   .  .  ..|||  |  .. | |..    ..    .  | ..   |     . |  |||| |.   |
QGRKDDLECWIYMVFDLMDPEHGMSWRKECDCNMMIKQKDNFMYHFDKHQYSHIPRRLKPLVSYVNGYQYDSTPDYDYFRNCL
Kinase R90.1.AA CK1-G 20-276 31 9.2e-40 132.4 In-house 1-266 (266) Show / Hide 
Range on Protein: 20-276
Range on HMM: 1-266/266
Sequence Identity: 31% (84 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKK-HACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTA
...  ||| | |||..| . . |  | |||| |  |     |. |    . | |.     . |  |   |.| .|| | |  | ||  .     | . | 
YRVGKKIGCGNFGELFEGKNMYN-NEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDL-FDWCDRKFSVKTV

VRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRN-VYMLDFGLARQYLNAKGEIRSP-RSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYML
. | ||... ....||   . ||||| ||  ||.|.   . ... |||.|.||   . .   | |      || ||  .  |  .|  | ||. .|  | 
CMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMF

TEFLQGQLPWR-----KIKDKDE-VGKMKEEADLVVLLDD--CPHEMHLFVAHLKVLGYADTPDYVYL
  || |.|||        | . . .|. | .    .|..    |...  .      | . ..||| ||
MYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL
Kinase R90.1.AA Pkinase 20-227 25 9.7e-22 77.95 Pfam 1-213 (293) Show / Hide 
Range on Protein: 20-227
Range on HMM: 1-213/293
Sequence Identity: 25% (57 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKM------EVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKN--LADLR----RE
..|. ||| |.||. |..... . . .||.|. . . .|   ..      |.....||. .   ...|.. ....  |.|| . ..   ..||     . 
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-

APKQCF--NLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSPRSAAGFRGTVRYAAVTAHK-NKEMG
  . ||     .. ..  ||| |.  .|| |..|||.||.|. . .. ..   |   |||||.|.      . . . . .| || .|.|   .. ... |
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG

RQDDLWSLFYMLTEFLQGQLPWR
.  | ||.  .| |.| |..|..
PKVDMWSCGCILYEMLCGRPPFP
Kinase R90.1.AA S_TKc 20-259 21 1.4e-17 65.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 20-259
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGK---NLADLRREAPK----QC
..|  ||| |.||. | ....   ...||||. .     . .. |...|..  . .. .|.|.. .. .. |.|| . .    .| |. .. ..    . 
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSPRSAAGFRGTVRYAA---VTAHKNKEMGR-QDD
|.  .| ..  ||....  .|| |..|||.||.|  . .      ..   |||||||.               | ||  | |   .        |.   |
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------------TTFCGTPWYMAPEVL------GYGKCKCD

LWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEADLVVLLDDCPH-----------EM-------HLFV
 ||.  .| |.| |. |..   ..    |..   ..  ... | .                    | ..
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase R90.1.AA TyrKc 20-280 18 1.5e-08 -84.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 20-280
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

WKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRL-QGKKHACKFYGCGRND-------KFNYLVM-SLQGKNLADLRREAPK
 . . |.| | |||.|..|      . ||.|.  . | .. .  |  ....|    ..  ..||. . .       .  ..||    . .| |  |.  .
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

QCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNA-----KGEIRSPRSAAGFR--GTVRYAAVTAHKNKEM
. ..... .   .|| .| . .|| .. |||    |   |.       |   ||||.|   .       ..  ....  | .    .|  |  . . .. 
K-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GRQDDLWSLFYMLTEFL-QGQLPWRKI----KDKDEVGKMKEEADLVVLLDD--------CPHEMHLFVAHLKVLGYADTPDYVYLESLL
  . | ||   .. | .  || |.  .    .. .|| .  .. .     ..        || ||.           .| |    . ...
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF