Gene par-4 (Nematode worm)

par-4

Species: Nematode worm
Alias: Y59A8_01348+, Y59A8B.14, Y59A8_01348, CE27410, aSWK041, par-4
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: V: 18101256-18109450, WormBase Genetic Map location: V:13.8582,

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
par-4.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
par-4.AA Protein Genbank 617 None Fasta, JSON

Protein domain

Protein domains of par-4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase par-4.AA LKB 183-446 56 9.69999999999e-233 698.04 In-house 1-265 (265) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-265/265
Sequence Identity: 56% (151 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNGWENIRSEMSILRRMNHRNVIKLIEIFNIPAKGKVYMVFEYCIGS-VQQLLDMEPARR
||.|...|.|||||||||.|.|||.||||||||..|||.|.|||.|...|..||.||.||.||.||..|....|.|.|||.|||... .|..|||.|..|
YMMGDVLGEGSYGKVKECMDSYTLCRRAVKIMKKKKLRRIPNGWQNVKKEIQILKRMHHRHVIQLIDVFYNEEKQKMYMVMEYCVCGTMQEMLDMQPCKR

LTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLFQRDGRCTKVNGTPKFQPPECIYGNHDFFDGYKADMWSAGVTLY
..|...|..|..||.|..||||.||.||||||||||...|.|.||||||||||...||||..||...|.|.||||||..||||.|.|.|.|.||.|||||
MPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRDDCCTTSQGSPAFQPPECANGNHDTFSGFKVDIWSMGVTLY

NLVSGKYPFEKPVLLKLYECIGTEPLQMPTNVQLTKDLQDLLTKLLEKDFNERPTCLETMIHPWF
|...||||||.....||.|.||.....||......||||.|....|..|.|.|..|...|.||||
NMTTGKYPFEGDNMYKLFENIGKCQWEMPCWYDCDKDLQNLIKGMLQYDHNKRFSCHQIMHHPWF
Kinase par-4.AA CAMKL 183-446 30 2.3e-104 333.98 In-house 1-297 (297) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

YMWGGQIGTGSYGKVKECID-MYTLTRRAVKIMKYDKLRKITNGWEN-----------IRSEMSILRRMN---HRNVIKLIEIFNIPAK----GKVYMVF
|  | ..|.||.|||| ... ..| .. |.||.. .|...... . |           || |..|....|   | |.||| |..  | .    .|.|.| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCIGS---VQQLLDMEPARR--LTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDF--TVKICDFGVAEQIN-L-FQRDGRCTKVNGTPKFQ
||| |     .. .. .. ||  .. .| . .|  .. ..||.||... | |||| |.|.. .   ..||.||| . ..    |...  ..   |.| ..
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPECIYGNHDFFDGYKADMWSAGVTLYNLVSGKYPFEKP--------VLLKLYECIGTEPLQMPTNVQLTKDLQDLLTKLLEKDFNERPTCLETMIHPWF
.|| . ||.. .||.|.|.||.||.||..| |..||. .           .||. | .   ..|  ...  |..||. |.|... ..|||. . | |||.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase par-4.AA CAMK 188-446 20 1e-80 259.67 In-house 1-425 (425) Show / Hide 
Range on Protein: 188-446
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

QIGTGSYGKVKECIDMYTL------------TRRAVKIMKYDKLRK------------------------ITNGWENIRSEMSILRR-------MNHRNV
..|.||.||||.||.  |             .. |.||.. .||..                          .  .|.|.|..|...       ..|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLIEIFN------------IPAKG------KVYMVF---EYCIGS------VQQLLDMEP------------ARRLTIGESHAIFIELCQGLNYLHSKR
|||.|..                |.      ..|||.   ||| |        . . . ..             .|.|  | . .|  .|....|.||. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VSHKDIKPGNLLVSID-----------------FTVKICDFGVA--EQINLFQR-------------------DGRCTKVNGTPKFQP-PECIYGNH---
. | |.|| |.|.. .                 ...||.||| |   . .  ..                   .  .. . ||| . . || . |..   
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------DFFDGYKADMWSAGVTLYNLVSGKYPFEKP-------------VLLKLYECIGTEPLQMP-----------------------TNVQLTKDL
           .|.|.||||.|| || ...|..||. .              . .|.| | .   ..|                       .. ..... 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQEC

QDLLTKLLEKDFNERPTCLETMIHPWF
.||. |.|..| ..|.|. . . |||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase par-4.AA S_TKc 183-446 29 2.1e-73 251.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-231/231
Sequence Identity: 29% (82 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNGWENIRSEMSILRRMNHRNVIKLIEIFNIPAKGKVYMVFEYCIG---SVQQLLDMEPA
|  . .|| |..|||. |..  |  . |.||.|           |.||.|..||.. .| |..||...|     ...|||.||| |   .. ....  . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

RR----LTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLFQRDGRCTKVNGTPKFQPPECIYGNHDFFDGY-KADMW
..    ..  .   .. ..|..|.|.||... | |.|| |.|..   ..||||||.| |.         | . ||| . .|| .        |. |.|.|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL------GYGKCKCDWW

SAGVTLYNLVSGKYPFEKPVLLKLYECIGTEPLQMPTNVQLTKDLQDLLTKLLEKDFNERPTCLETMI-------HPWF
| |..|| ...|. ||.   . .... ||            .... |.. |.|.|| ..|||. | .        ||||
SCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase par-4.AA CAMKK 183-446 23 6.4e-61 191.91 In-house 1-396 (396) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-396/396
Sequence Identity: 23% (94 aa)

YMWGGQIGTGSYGKVKECIDMYT-LTRRAVKIMKY----DKLRK----------------------ITNGWENIRSEMSILRRMNHRNVIKLIEIFNIPA
|  . .|| |..||||  .. |.  .  |.|| .     .|| |                      ..|. ... .| .|....|| |..||.|. . | 
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

KGKVYMV-FEYC-IGSVQQLLDMEP-----------------------ARRLTIGE---------------------SHAIFIELCQGLNYLH-SKR---
  |.||| .|||  |... . . ..                          ..  .                        .| . ..|| ||| ..    
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------VSHKDIKPGNLLVSIDF---TVKICDFGVAEQI-NLFQRDGRC--------TKVNGTPKFQPPECIYG-NHDF-----------
                . |.|||| |.|.. .    .|||.||||. .     |.. .|         | .||| |..|| .   |  .           
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-FDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLYE---CIGTEPLQMPT-----------NVQLTKDLQDLLTKLLEKDFNERPTCLETMIHPWF
 ..| .||.|..||||| .| || ||    |..|..    |  .|.. |.           .  .. ||.||....|||.. .| |  .   |||.
IYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase par-4.AA Pkinase 183-446 29 5.6e-60 210.38 Pfam 1-293 (293) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNGWENIR-SEMSILRRMNHRNVIKLIEIFNIPAKGKVYMVFEYCIGSVQQLLDME----
|  |..|| ||.|.|..|..  |  . ||||.|..  .|     ...| || .|..|.|| |...|...|    |...|||.||| | .  ..|      
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY-VMDLFDYIS

--PARRL--TIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTV----KICDFGVAEQINLFQRDGRCTKVNGTPKFQPPECIYGNHDFFDGY
    ...  .  |   .. ....||.|.||... | |.|| |.|.. . ..    ||||||.|.|..   ... .| . ||| . .|| |   ..  .|.
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR--GGQYYGP

KADMWSAGVTLYNLVSGKYPFEKP------VLLKLYECIGTEPLQMPTNVQLT-------------------KDLQDLLTKLLEKDFNERPTCLETMIHP
|.||||.|..|| ...|. ||           ..... |.  ||  .     .                   ....|.....|.|| ..|||. . . ||
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WF
||
WF
Kinase par-4.AA Ciliate-E2 183-446 22 2.8e-57 195.17 In-house 1-365 (365) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRA----------------VKIMKYDKLRKITNGWENIRSEMSILRRMN----------------HRNVIKLIEI
|    .||.|..|.|..| .  .  . |                |||..| . ... |. |.| .| .|.|..|                | |.||..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FNIPAKGKVYMVFEYCIG-SVQQLLD----MEPAR-----RLTIGESHAIFIELCQ---------------GLNYLHSKR-VSHKDIKPGNLLVSIDFTV
|    . ..|.|.||| | . ....      ..       ..|. |   |. ...|               .|.|||||  . | |||| |.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KICDFGVAEQINLFQRDGR-------CTKVN-----------------------GTPKFQPPECIYGNH------DFFDGYKADMWSAGVTLYNLVSGKY
||.||| . ... .. ...       ..  .                       ||| ...|| . |            .||.|.||.||.|| ...||.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFEKPVLLKLYECIGTE-PLQMPTN----------------VQLTKDLQDLLTK----LLEKDFNERPT-CLETMIHPWF
||         . .  . ... | .                 ..... .||. |    .|.|| ..|.|   . . ||||
PF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase par-4.AA Ciliate-E2-Unclassified 183-446 23 4.5e-48 164.85 In-house 1-352 (352) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-352/352
Sequence Identity: 23% (86 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRR-----AVKIMKYDKLRKIT--------NGWENIR--------SEMS-ILRRMNHRNVIKLIEIFNIPAKGKVY
|  . |||.|..|||..|..  .         . ||..|... . .        . ..|.          .|  ||. ..| ...|....|.   | ..|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQD--KQNIY

MVFEYC----------------IGSVQQLLDMEPARRLTIGESHA-------IFIELCQGLNYLHSK-RVSHKDIKPGNLLVSID---FTVKICDFGVAE
.| |||                .  ....|..   .|  . | .|       .| ...|||.|||.|  . | |||| |.|.. .   . .||.||| . 
IVMEYCEGGDLWQYIKKRKKQKQ--KGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISK

QINLFQ-------------RDGRCTKVNGTPKFQ----PPECIYG-NHD---FFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLK---------------
... ..             .. ... . ||| ..    .||.. | |.|   .   ||.|.|| || || .. |.|||. .   .               
KYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA---YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

-LYECIGTEPLQMPT--N----VQLTKDLQDLLT----KLLEKDFNERPTCLETMIHPWF
 ||. |   ..| |   .     .. .  .|...    |.|.|. |.|.|  . . ||||
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase par-4.AA STE 184-446 20 7.7e-46 158.6 In-house 1-359 (359) Show / Hide 
Range on Protein: 184-446
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

MWG-GQIGTGSYGKVKECIDMY---------------TLTRRAVKIMKYDKLRKITNG--------------WENIRSEMSILRRMN--HRNVIKLIEIF
  | ..|| |..|.|  ....                | .. |.|.|.... ..                  ...|  |..|....|  | |..| .  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

N-----IPAKGKVYMVFEYCI-GSVQQLLDM--EPARRLTIG--------ESHA--IFIELCQG-LNYLHSKRVSHKDIKPGNLLVSIDFTVKICDFGVA
        ........ ||.  ||. ....   .. ..|..         ||    |  ....| |.||||... | ||||.| |.     ||.|||||.
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

EQINL--------------FQRDGRCTKVNGTPKFQPPECIYG-NHDFF-DGY--KADMWSAGVTLYNLVSGKYPFEK-PVLLKLYECI--G--------
 |..                 ...... . ||| .  || | . ...   .||  |.|.|| | |.  .. ||.|. . . .  ... .  .        
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

-----TEPLQMPTNVQ-----------------LTKDLQDLLTKLLEKDFNERPTCLETMI--HPWF
      .| . |....                 ......| . | |.|| |.|||  . .   ||..
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase par-4.AA ULK 183-446 25 2.5e-41 142.07 In-house 1-329 (329) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-329/329
Sequence Identity: 25% (83 aa)

YMWGGQIGTGSYGKVKECIDMYT----LTRRAVKIMKYDKLRKITNG------WENIRSEMSILRRMN--------HRNVIKLIEIFNIPAKGKVYMVFE
|    ..| ||.||| . ... |        |.|..  .|.... |       |. ...|  |.....        | |..||...|. .    .|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCIG-SVQQLLD-----MEPA---RRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDF------------TVKICDFGVAEQINLF--QRD
|| |   .|..      .|.    .||.  |   .|. ...|. .||.... | |||| | |.. ..            ..||.||| | ... .  . .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

GRCTKVN-----GTPKFQPPECIYGN--HDFFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLY-----ECIG----------TEPLQMP---TNVQLT
  .| ||     ||| .  |. . |.  .  .. ||.|.|| |. .| .. ||.||...   ..|     . |           ..||| |    ..|. 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

KDLQDLLTKLLEKDFNERPTCLETMIHPWF
....||. ..|..| ..| .  |   ||||
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase par-4.AA ULK 183-446 26 5.5e-41 142.49 In-house 1-324 (324) Show / Hide 
Range on Protein: 183-446
Range on HMM: 1-324/324
Sequence Identity: 26% (85 aa)

YMWGGQIGTGSYG-KVKECIDMYTLT-RRAVKIMKYD--KLRKITNG------WENIRSEMSILRRMN---HRN--VIKLIEIFNIPAKGKVYMVFEYCI
|    ..| ||.| || . ... | |   .|.. . |  |..|. |       |.....| .|.. ..   | |  ..||...|. .    .|...||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

G-SVQQLLD-----MEPA---RRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDF------------TVKICDFGVAEQINL--FQRDGRC
|   .|..      .|     .||.  |   .|. .|.|. .||.. . | |||| |.|.. ..            ..||.||| | ...   .. . . 
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TKVN-----GTPKFQPPECIYGN--HDFFDGYKADMWSAGVTLYNLVSGKYPFEKPVLLKLY----ECIG----------TEPLQMP---TNVQLTKDLQ
| ||     ||| .  |. . |.  .  .. ||.|.|| |. .| .. |||||...   ..|    . |           ..|.| |    .... ....
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLTKLLEKDFNERPTCLETMIHPWF
||. ..|..| ..| .  |   ||||
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase par-4.AA MARK 183-330 33 2.4e-35 113.14 In-house 1-151 (262) Show / Hide 
Range on Protein: 183-330
Range on HMM: 1-151/262
Sequence Identity: 33% (51 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNGW-ENIRSEMSILRRMNHRNVIKLIEIFNIPAKGK-VYMVFEYCIG-SVQQLLDMEPA
|. . .||.|||.||| ...  | .. |.||  |.| ..  . | .|...|..|.....| |.||| ...  . ... .|.. ||. | .. . .   | 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKI--YEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN

RRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDF--TVKICDFG
.||.  | ..||  .. ..||.|||.. | |||| |.|.  .    .||.|||
GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFG
Kinase par-4.AA MARK 367-446 37 6.6e-21 65.22 In-house 183-262 (262) Show / Hide 
Range on Protein: 367-446
Range on HMM: 183-262/262
Sequence Identity: 37% (31 aa)

DGYKADMWSAGVTLYNLVSGKYPFEKPV--LLKLYECIGTEPLQMPTNVQLTKDLQDLLTKLLEKDFNERPTCLETMIHPWF
||.|.|.|| || || .|.|..||.     . .||. | ..  . |..  . |....|. .||  . .||||. | | |||.
DGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH--VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase par-4.AA TyrKc 183-441 22 1.8e-13 -5.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 183-441
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YMWGGQIGTGSYGKVKECIDMYTLTRRAVKIMKYDKLRKITNGWENIRSEMSILRRM--NHRNVIKLIEIFNIPAK-----GKVYMVFEYC-IGSVQQLL
   | ..| | .|.| ..  ... .  ||| .| |.        | ...|..|...   .| |...|. .   .       . ...|.||.  |. .. |
ITLGKKLGEGAFGEVYKG--TWK-IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-DMEPARRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTVKICDFGVAEQINLF------QRDGRCT---KVN--GTPKFQPPECIYGN
 . .|   |.  . . . .  ..| .|||||.. | |.   | ||. ..||||.||| .  |         .   | .     .     .  .||||  |
RKHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--N

HDFFDGYKADMWSAGVTLYNLVS-GKYPFEK-----PVLLKLYECIGTE-PLQMPTN------VQLTKDLQDLLTKLLEKDFNERPT---CLETM
.  |   | | || ||... . . |. | .           ..|.. .   .  | |      |  .... .. ..  . | ..|||   . | .
YGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase par-4.AA Pkinase_Tyr 183-332 25 4.7e-09 31.29 Pfam 1-158 (270) Show / Hide 
Range on Protein: 183-332
Range on HMM: 1-158/270
Sequence Identity: 25% (41 aa)

YMWGGQIGTGSYGKVKECIDM----YTLTRRAVKIMKYDKLRKITNG---WENIRSEMSILRRM-NHRNVIKLIEIFNIPAKG-KVYMVFEYCIG-SVQQ
   | ..| |..|.|....       | .  |||..|     . .     .|   .|..|.. . .| |...|. .     .  ..|.|.||. . .   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

LLDME--PARRLTIGESHAIFIELCQGLNYLHSKRVSHKDIKPGNLLVSIDFTVKICDFGVA
 |     . ..||. .   . .. ..|..||.||.  | |.   | ||. ...||||||| |
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA