Gene odr-1 (Nematode worm)
odr-1
Sequence
Protein domains of odr-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | odr-1.AA | RGC | 493-754 | 27 | 3.4e-104 | 352.45 | In-house | 1-300 (300) | Show / Hide |
Range on Protein: 493-754 Range on HMM: 1-300/300 Sequence Identity: 27% (82 aa) T-QRAEYVQFKQI---RKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIM----TMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQY . ... . ...|. |...|...... |. ..|||||||.||.|........ .|.|.. . .||.|.... ..|..||..||..|.|||.||.|| EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY LHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKV---------PEQAAHMITYPQYVCFPPEHIREYDDSGKQP--PRVVRGSPKGD ||.|.|.|||.| ..|..| .||.|.| .|..|.. .......|.. .| ....|... ...|||.||.. ..... ....||..||| LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD IYCVGMIFYMMVEREDPYHLIHSVERP--NATLIKQILNEN-----------HMPRITDDYR-----QENMLLEMCKECWDRNPDKRPT-IKKLIESIST .|..|.|.|... |. |..|.. ...| ... ..|. |. ..| | .| . . ||.....||...|..||. .... . ..| VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT |
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Kinase | odr-1.AA | RGC | 493-754 | 27 | 3.4e-104 | 352.45 | In-house | 1-300 (300) | Show / Hide |
Range on Protein: 493-754 Range on HMM: 1-300/300 Sequence Identity: 27% (82 aa) T-QRAEYVQFKQI---RKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIM----TMTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQY . ... . ...|. |...|...... |. ..|||||||.||.|........ .|.|.. . .||.|.... ..|..||..||..|.|||.||.|| EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY LHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKV---------PEQAAHMITYPQYVCFPPEHIREYDDSGKQP--PRVVRGSPKGD ||.|.|.|||.| ..|..| .||.|.| .|..|.. .......|.. .| ....|... ...|||.||.. ..... ....||..||| LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD IYCVGMIFYMMVEREDPYHLIHSVERP--NATLIKQILNEN-----------HMPRITDDYR-----QENMLLEMCKECWDRNPDKRPT-IKKLIESIST .|..|.|.|... |. |..|.. ...| ... ..|. |. ..| | .| . . ||.....||...|..||. .... . ..| VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT |
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Kinase | odr-1.AA | TKL | 519-752 | 15 | 8.3e-17 | 57.05 | In-house | 78-364 (364) | Show / Hide |
Range on Protein: 519-752 Range on HMM: 78-364/364 Sequence Identity: 15% (47 aa) SLKQLQHDNLAKFYG--IQVNDD-IMT--------MTILHTLVERGTLEEFCLDRDFGMDDTFKSAFMRDILKGLQYLHKSSI-------GYHGHLQAST ....|.|.|. .|.| .. ... .. . | ....|.|... . .. ... ...|| .|..||| . | | . MMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCR--WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKN CLIDINWV--------------LKLTLYGVSNFMSDQLD-------------------AENIKV-------PEQAAHMITYPQYVCFPPEHIREYDDSGK .|.| || .|.. .| | ||| . . . .. || .. |...| ILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGI------------- QPPR--VVRGSPKGDIYCVGMIFYMMVEREDPYH-LIHSVERPN---ATLIKQILNENHMPRITDDYRQ-------ENM---LLEMCKECWDRNPDKRPT . . |.| |.| |.... .. |. ||. . .. . .. .... .... | | . .. ... . . ...||| .|.|||. DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPS IKKLIESI ..... . FQEILKRL |
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S_TKc | odr-1.AA | S_TKc | 479-754 | 15 | 4.9e-09 | -44.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 479-754 Range on HMM: 1-231/231 Sequence Identity: 15% (46 aa) TSRRRVFGSYALVGTQRAEYVQ------FKQIRKINFPETTLDYLYSLKQLQHDNLAKFYGIQVNDDIMTMTILHTLVER--GTLEEFCLDRDFG----- |. |. | .. . |.|. |... . ||. .|.|. |.|.. .. . . ... |.| .. .| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP MDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRV .. .|. |...|.|.|. | | | . |.| ..|.. |.. .. ... | |. .|| . FPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYM--APEVL------------- VRGSP-KGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNENHMPRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIE-------SIST .. | |.. .| |.| |. .. |.. ....|.|. .... . |....|.||||. .. . -GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | odr-1.AA | TTK | 715-748 | 37 | 1e-06 | 17.89 | In-house | 304-338 (344) | Show / Hide |
Range on Protein: 715-748 Range on HMM: 304-338/344 Sequence Identity: 37% (13 aa) PRITDDY-RQENMLLEMCKECWDRNPDKRPTIKKL | .. | . . ||... | | |||.||..| .| PEHPPYYEKINKMLIHVMKCCLYRNPKKRWSIPEL |
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Kinase | odr-1.AA | Fer | 701-753 | 24 | 2e-06 | 17.91 | In-house | 228-283 (283) | Show / Hide |
Range on Protein: 701-753 Range on HMM: 228-283/283 Sequence Identity: 24% (14 aa) NATL----IKQILNENHMPRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIESIS .... .|.| ....|..... | | . |.| ||...|..||| |.... . MTNVKKQARKWIIKKGYMMPMPNHMPPEIMQI-MMKQCWQKDPEDRPTMKEICQKLK |
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Kinase | odr-1.AA | LRRK | 703-754 | 22 | 2e-06 | 18.53 | In-house | 296-351 (351) | Show / Hide |
Range on Protein: 703-754 Range on HMM: 296-351/351 Sequence Identity: 22% (13 aa) TLIKQILNENHMPRITDDYRQEN-----MLLEMCKECWDRNPDKRPTIKKLIESIST ..|... .| . | | .| . |... ..||. .|.|||. . .. .|. EQIEDKIIEGLRPTIPQHY-CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
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Kinase | odr-1.AA | TK | 729-752 | 33 | 3e-06 | 16.23 | In-house | 463-486 (486) | Show / Hide |
Range on Protein: 729-752 Range on HMM: 463-486/486 Sequence Identity: 33% (8 aa) EMCKECWDRNPDKRPTIKKLIESI .....||...|..||| . | | . DLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | odr-1.AA | TKL-ciliate1 | 673-752 | 23 | 2.1e-05 | 14.44 | In-house | 201-279 (279) | Show / Hide |
Range on Protein: 673-752 Range on HMM: 201-279/279 Sequence Identity: 23% (20 aa) DIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNEN---HM--PRITDDYRQENMLLEMCKECWDRNPDKRPTIKKLIESI ||| .| . | .. |. |. . || . .. . . . | |. |. . .. . ||..|| ||| .|. . DIYAYGIVMYILCFRKTPFQQKMSV----INIMCYWCEFPGRPNLGPQFIHFDCPQN--FHNLMMRCWCQNPNKRPNFNEIIQIL |
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Kinase | odr-1.AA | STE | 669-750 | 16 | 3.1e-05 | 14.57 | In-house | 246-353 (359) | Show / Hide |
Range on Protein: 669-750 Range on HMM: 246-353/359 Sequence Identity: 16% (18 aa) SPKGDIYCVGMIFYMMVEREDPYHLIHSVERPNATLIKQILNE---------NHMPRITDDYRQE-----------------NMLLEMCKECWDRNPDKR . | ||...| |.. . |.| | . ....... . .. |.. |. |. . . . | ...|.|| DTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR PTIKKLIE || ..|.. PTASQLLK |
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TyrKc | odr-1.AA | TyrKc | 479-752 | 11 | 4.1e-05 | -139.97 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 479-752 Range on HMM: 1-280/280 Sequence Identity: 11% (42 aa) TSRRRVFGSYALVGTQRAEYVQF----KQIRKINFPETTLDYLYSLKQL--QHDNLAKFYGIQVND-----DIMTMTILHTLVERGTLEEFCLDRD--FG . .. |. | .... | ... | .. . ...| .|.|. ..||. . . | . |. ... | | .. .. . ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC MDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLYGVSNFMSDQLDAENIKVPEQAAHMITYPQYVCFPPEHIREYDDSGKQPPRV |.| . |. .| .| .|||. .. MKDLLS--FCWQIACGMEYLHSK---------------------------------------------------------------------------NC V-------------------------RGSPKG-------DIYCV-----GM------------IFYM-----------------MVEREDPYHLI---HS . | . | | . | |.| . . .. . . IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ- VERPNATLIKQILNENHMPRITDDYRQENM--------LLEMCKECWDRNPDKRPTIKKLIESI .|. .|... . . ||. .|| . | . .. |.||...|..||| . ..| . -MMSNQEVIEYVKQGYRMPQPPNDY--P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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Kinase | odr-1.AA | Dicty4-Unclassified | 523-617 | 29 | 8.2e-05 | 12.37 | In-house | 55-156 (263) | Show / Hide |
Range on Protein: 523-617 Range on HMM: 55-156/263 Sequence Identity: 29% (30 aa) LQHDNLAKFYGIQVND--DIMTMTILHTLVERGTLEEFCL------DRDFGMDDTFKSAFMRDILKGLQYLHKSSIGYHGHLQASTCLIDINWVLKLTLY .|| || | || .| || | . .|.| | .. .||| .. || .|.|.|| . | . .| |.| . | IQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNF-IHRDIKSSNILMDKHFNIKIADF GVS |.| GIS |
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Kinase | odr-1.AA | Pkinase_Tyr | 732-752 | 38 | 9.6e-05 | 16.69 | Pfam | 250-270 (270) | Show / Hide |
Range on Protein: 732-752 Range on HMM: 250-270/270 Sequence Identity: 38% (8 aa) KECWDRNPDKRPTIKKLIESI |.||. .|..||| . ..| . KQCWHYDPEDRPTFSEIHEQL |
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Kinase | odr-1.AA | Pkinase | 669-752 | 16 | 0.000123 | 17.47 | Pfam | 190-293 (293) | Show / Hide |
Range on Protein: 669-752 Range on HMM: 190-293/293 Sequence Identity: 16% (17 aa) SPKGDIYCVGMIFYMMVEREDPYHLIH----SVERPNATLIKQILNENHMPRITDDYRQ----------------ENMLLEMCKECWDRNPDKRPTIKKL .|| |.. .| |.| |. .. |. | . .... . . ..| .. ... . . ... .| |....| ||||.. . GPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI IES--I .. . LQHPWF |
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Kinase | odr-1.AA | Dicty4-Unclassified | 732-752 | 42 | 0.001163 | 8.37 | In-house | 243-263 (263) | Show / Hide |
Range on Protein: 732-752 Range on HMM: 243-263/263 Sequence Identity: 42% (9 aa) KECWDRNPDKRPTIKKLIESI | || | ||||. . |. KWCWHNDPNKRPTMNQIIQYL |
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Kinase | odr-1.AA | STE | 520-590 | 20 | 0.011915 | 5.33 | In-house | 82-173 (359) | Show / Hide |
Range on Protein: 520-590 Range on HMM: 82-173/359 Sequence Identity: 20% (19 aa) LKQLQ--HDNLAKFYGIQVNDDIM-----TMTILHTLVERGTLEEFCL---DRDFGMD----------DTFKSAFMRDILKG-LQYLHKSSI .|... |.| |.|| .... . | ... |.|... . .... . ... |.|||| |.|||. | MKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHI |
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Kinase | odr-1.AA | TKL-ciliate1 | 576-587 | 58 | 0.015541 | 4.49 | In-house | 110-121 (279) | Show / Hide |
Range on Protein: 576-587 Range on HMM: 110-121/279 Sequence Identity: 58% (7 aa) RDILKGLQYLHK .||..|.||||. KDIAQGMQYLHM |
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Kinase | odr-1.AA | TK | 520-592 | 8 | 0.118118 | 0.45 | In-house | 92-261 (486) | Show / Hide |
Range on Protein: 520-592 Range on HMM: 92-261/486 Sequence Identity: 8% (14 aa) LKQLQ-----HDNLAKFYGIQVNDDIMT----------MTILHTLVERGT----LEEFCLD-RDFGMDDTFKSA-------------------------- .|... |.|. ..||. . .. .. . |. ... | | .. . |. ... ... MKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESN -----------------------------------------------FMRDILKGLQYLHKSSI----GY ....| .|..|||. . .. SPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNF |
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Kinase | odr-1.AA | Pkinase_Tyr | 520-534 | 43 | 2.25143 | 1.89 | Pfam | 57-72 (270) | Show / Hide |
Range on Protein: 520-534 Range on HMM: 57-72/270 Sequence Identity: 43% (7 aa) LKQL-QHDNLAKFYGI .||| .|.|. ..||. MKQLGHHPNIVRLYGV |
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Kinase | odr-1.AA | Pkinase | 574-590 | 47 | 3.824902 | 1.59 | Pfam | 113-129 (293) | Show / Hide |
Range on Protein: 574-590 Range on HMM: 113-129/293 Sequence Identity: 47% (8 aa) FMRDILKGLQYLHKSSI .|. ||.||.|.|. .| YMYQILRGLEYCHSMGI |
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CYCc | odr-1.AA | CYCc | 791-985 | 36 | 1.3e-94 | 321.5 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 791-985 Range on HMM: 1-231/231 Sequence Identity: 36% (85 aa) DAQMQTMRLLNEMLPASIAKDLKNGL-IMPPRSYESATVMFVQICDFNALMKRSSPEQVIAFLNDIYDQFDTVIKRHD-----AYKVETTGETYMVASGV .......|||..|||...|..||.|. ..| .|...|..| |..|..|.....|.||. .|||.|..||..|.||. .||||| |..|||.||. MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC PHENEG-------------------RHIFEVAEISLEIREISYIYVLQHDK----NYKLRIRIGFHAGPIAAGVIGIRSPRYCLFGDTVNFASRMQSNCP |..|| .|. ..|...|...|.. .. .|| . ...||.|||.| ||...||.|||.||||.|||||| ||||.|.. PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD PNQIQTSEITARLL-------FDSHEYKFVK |.||. || | ..| ... . | PGQIHVSEETYWCLCLDQFERRRCGQFEFEP |
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Guanylate_cyc | odr-1.AA | Guanylate_cyc | 818-996 | 37 | 4.6e-54 | 190.71 | Pfam | 1-203 (214) | Show / Hide |
Range on Protein: 818-996 Range on HMM: 1-203/214 Sequence Identity: 37% (76 aa) MPPRSYESATVMFVQICDFNALMKRSS----PEQVIAFLNDIYDQFDTVIKRH--DAYKVETTGETYMVASGVPHE-----NEGRHIFEVAEISLEIREI ... .|.. |.|| .| .|.|. |.| |.|.. .|||.| ||... .| . |||.| | .||..||.| . . |. .|...|.. | VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY SYIYVLQHDKNYK------LRIRIGFHAGPIAAGVIG--IRSPRYCLFGDTVNFASRMQSNCPPN--QIQTSEITARLLFDSHEYKFVK----RGIVHVK .| .|..|. ...||| | || ||||| .| ||||..||||| ||||.|. |. .|. || |.|.| . .. |.. ||...|| CQ-QVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVK GKGN |||. GKGK |