Gene mig-15 (Nematode worm)

mig-15

Species: Nematode worm
Alias: ZC504.4, ZC504.4A, aSWK305, ZC504.4a, mig-15, CE25672
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 10397643-10390724, WormBase Genetic Map location: X:1.7695,

Classification

Group: STE
Family: STE20
Subfamily: MSN

Sequence

Name Sequence Type Origin Length Description Download
mig-15.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 268 Kinase domain by global Sugen HMM Fasta, JSON
mig-15.AA Protein Genbank 1087 None Fasta, JSON

Protein domain

Protein domains of mig-15.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase mig-15.AA MSN 21-288 82 2.3e-201 671.02 In-house 1-265 (265) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-265/265
Sequence Identity: 82% (220 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTKG
|||.|||||||||||||||||||.||||||.|...||||.|||.|||||||.|||||.|||||||||| |.  |...|||.||||||.||.|||||.|||
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPP--GHDHQLWMVMEFCGAGSVTDLVKMTKG

GSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGIT
 ||||.|||||||||||||.||||.|||||||||||||||..|||||||||||||||.||||||||||||||||||||||||.|.||||.||||||.|||
QSLKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGIT

ALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
|.|||||.|||||||||||||||||||||||| .|||.|||..|.|..|.|.|||||||...|.||||
AIEMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase mig-15.AA STE20 21-288 49 3.3e-159 535.23 In-house 1-288 (288) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-288/288
Sequence Identity: 49% (146 aa)

FELIEVVGNGTYGQVYKGRHVKTAQL----AAIKIMNINE-----DEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSI
.||.|..|.|.||.|||..|..| ..    .|||.||...     ||...|. ||...|.   | |. .|||...|. .     .|.||.|||.|| ||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC----DDELWIVMEYCGGGSL

TDLVKN--TKGG-----SLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDK----TVG-RRNTFIGTPYWMAPEVIA
||..|.  ..|.     ...||.|||||||.|.|| .||. ..||||||..|.|||...||||.||||.|||.|    | . .||||.|||||||||||.
TDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQ

CDESPEATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIP--RNPPPKLKR--NKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
|.|.|.  ||...| |||||||.|||||.||..|||||||.|.||  .||||.||    .||...|  |... |.||...|| .  ||.||||
CMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase mig-15.AA STE 21-288 36 2.4e-128 432.69 In-house 1-359 (359) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-359/359
Sequence Identity: 36% (132 aa)

FELIEVVGNGTYGQVYKGRHVK---------------TAQLAAIKIMNINE------------------DEEDEIKLEINMLKKHSH-HRNVATYYGAFI
.|.||..|.|..|.|||....|               | .. |||.||...                  .|...|. ||...|| .| | |. .|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KKLPSSTGKHDQLWLVMEFCGSGSITDLVKN--TKGGSLK----------EEWIAYICREILRG-LYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVS
|. .  .. .|.||..||... ||..|..|.   .|..|.          |..||||||.||.| ||.||. ..||||||..|.||     |||.||||.
KEGHN-HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

AQLDK---------------TVG-RRNTFIGTPYWMAPEVIACDESP-EATYDSRSDLWSLGITALEMAEGHPPLCDMHPMRALFLIPRN----------
.||..               | . .||||.||| ||||||| ..... .  || ..| ||||.|..|||.|.||..|||||||.|.||.|          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----PPPKLKR-----------------NKKWTKKFETFIETVLVKDYHQRPYTGALLR--HPFI
     |||.|.                   .||...|  ||.  |.||...|| .  ||.  ||||
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase mig-15.AA NinaC 21-288 51 4.3e-128 431.85 In-house 1-267 (267) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-267/267
Sequence Identity: 51% (140 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKN--T
.| .| .| |||| |.|    .  |.||.||.   .| . ||  | | |.. . | ||  .|| . || .      ||||.|||.|  ||.||.||    
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNG---DQLWFVMEYCNGGSVTDMVKGLLK

KGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLG
 |  ..|| |||| .| ..|| |||. .|||||.|| |.|||    |||.||||||||| | .|||| .|||.||||||||| .. . .|| | | ||||
CGRRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLG

ITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
||| |.. | ||. |||||||.| |||||||.| .  .| ..|  ||   | ||| .||    .| ||||
ITAIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase mig-15.AA YSK 21-288 46 2.2e-119 361.24 In-house 1-257 (257) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-257/257
Sequence Identity: 46% (127 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEED--EIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNT
|   |..| | .| ||||  ..| .  |||| .  ..|..   |  ||. |       ..  |||.. |           || .||.|| ||. || |  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLKDT--------KLWIIMEYCGGGSCLDLMKPK

KGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIAC--DESPEATYDSRSDLWS
  |.. |. || | |||| ||  ||. ..||||||  ||||. . .||| ||||..|.  |. .||||.||||||||||| .  ..     ||.  | ||
YVGQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSY-----YDFKADIWS

LGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
|||||.||| |.||.||.||||..|||| |.||||.  ....| |  |.|  |.||  |||    || | ||
LGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase mig-15.AA MST 21-288 46 9.1e-107 340.41 In-house 1-254 (254) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-254/254
Sequence Identity: 46% (126 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINED-EEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTK
|...|  | | ||.|||  | .| .. |||....||| .  ||. ||... .     .. .||| ..        |. ..|.|||.|| ||. |..| |.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQ--EIIKEISIM-QQCKSKYIVKYYGSYFD------AKNNHCWIVMEYCGMGSVCDIMKITQ

GGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGI
   | |. || |..  |.||. ||..| ||||||  | ||    | || |||||.||  | . |||.||||||||||||      |  ||.  | |||||
-RTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLGI

TALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
||.|||||.||. | |||||.|.|| .|||..|   .|   |  |.   |.|.  ||.    || ||||
TAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase mig-15.AA KHS 21-288 46 1.3e-104 352.87 In-house 1-258 (258) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-258/258
Sequence Identity: 46% (125 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE-DEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTK
.||.  || ||||.||| |.... .|||.|.. .. ...   |. || |.|.  .| |.  |.|.....        |.||..||.||.||. |. . | 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKD-CRHPNIVAYFGSYLRR--------DKLWICMEYCGGGSLQDIYHVT-

GGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGI
 |.|.|  |||.|||.|.||..||. . .|||||| |.||||. .||| |||||||.  |...|  |||||||||||| | .   .  |.   |.|..||
-GPLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVER--KGGYNQLCDIWAVGI

TALEMAEGHPPLCDMHPMRALFLIPRNP--PPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
||.|.||  ||. |.||||||||. .    |||||  .||...|  |. . |.|.  .||    ||.|||.
TAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase mig-15.AA PAKL 21-288 42 1.5e-92 313.73 In-house 1-256 (256) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-256/256
Sequence Identity: 42% (115 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINED-EEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTK
||. |  | | || |||. |  |    ||| . | |  |  .|  ||..|||     |.  |.|    ||       ...|  |..|  ||| |. . . 
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKK-CKCPNIVSYFGSIQQKL-------NHYWILMDYCSLGSINDMMESC-

GGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVG-RRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLG
. .|.|. |. | .  |.||  ||.. .||||||  |.||.  . ||. ||||| ||. . .   |  ||||||||||.|       . |..  | ||||
CKTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIIN-----KQNYNNKCDIWSLG

ITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
||| |||.| ||. || ||||.  ||. |||...  |.| . |  |. . .|||  .|.    || ||||
ITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase mig-15.AA PAKA 21-288 39 3.2e-91 309.34 In-house 1-260 (260) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-260/260
Sequence Identity: 39% (107 aa)

FELIEVVGNGTYGQVYKGRHVKTAQL--AAIKIMNINEDEED-EIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKN
.. .| .| |  |.||..  .|| |    ||| ||....     |. || ..|. ..| |.  |. ...          |.||.|||. . |. ||....
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKE-CKHKNIVNYIDSYL------V--DDELWVVMEYMEGGCLTDVITQ

TK---GGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDL
.     . ..|. |||.|||.|.||  .|. ..||||||  |.||   ..||. |||  ||| .   .|||  |||||||||||   .     ||   | 
CCNIQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDI

WSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
||||| |.||.|| ||  .. | ||..||  |  |..|   ||...|  | .. | .|  .|. .  ||.|||.
WSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase mig-15.AA S_TKc 21-288 29 1.4e-86 294.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-231/231
Sequence Identity: 29% (84 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGS--GSITDLVKNT
.|.....| |..|.|||.||.|| .. ||||..      . |. ||..|||  || |. ..|..|           | |..|||.|.   |.  |. |. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKR

KGGS----LKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDS-RSD
...     . | ........|...| ..|. ..||||.| .|.||..  ..|. |||...||       .||.|||..|||||.         |.  ..|
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCD

LWSLGITALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLR-------HPFI
 ||.|..  ||. | || .  .... . .|              .. .  ||.  |.||  .||    .|.       ||..
WWSCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase mig-15.AA SLK 21-288 39 4.1e-86 290.52 In-house 1-259 (259) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-259/259
Sequence Identity: 39% (106 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEE-DEIKLEINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSGSITDLVKNTK
.|.|  .|.| .|.||| .|  . ..|| |...|...|| ..   ||..| .   | |.   |.|.           ..||...|||. | . | .    
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYY--------YDNKLWMMIEFCDGGAV-DNIMVEL

GGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKTVGRRNTFIGTPYWMAPEVIACDESPEATYDSRSDLWSLGI
. .|.|. |.|.|.... .| .||. ||||||.|  |.|.|   .|.| ||||||.. .|. .| |||||||||||||..|. . .. || ..|.|||||
EHPLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGI

TALEMAEGHPPLCDMHPMRALFLIPRNPPPKLKRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
| .|||.. ||  .| ||| |. | .  ||.|..  .|.|.|. |..  |||| ..|. |  |..|...
TLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase mig-15.AA Pkinase 21-288 26 1.2e-70 245.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-293/293
Sequence Identity: 26% (81 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKL-----EINMLKKHSHHRNVATYYGAFIKKLPSSTGKHDQLWLVMEFCGSG----SI
.......| |..|.|||..|..| .. |.||..  ...... .      || ..|.  .| |. ..|..|          .| ...|||.|. |    . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------KDHIYMVMEYCEGGLYVMDL

TDLVKNTKGGSL--KEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEV----KLVDFGVSAQL-DKTVGRRNTFIGTPYWMAPEVIACDESP
 |...  ..|..   |. .  ....|||||...|. ..||||.| .|.|. .  ..    |. |||...|.     .  .|| |||..||||||      
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----G

EATYDSRSDLWSLGITALEMAEGHPPLCDM----HPMRALFLIPRNPPPKLKRNKKWT---------------------KKFETFIETVLVKDYHQRPYT
   |....| ||.|..  ||. |.|| ..     . .. ...| |. .|.|...  |.                     . .  ||.  | || ..||  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

GALLRHPFI
  .| ||..
EQILQHPWF
Kinase mig-15.AA Pkinase_Tyr 21-243 24 1.9e-28 97.0 Pfam 1-228 (270) Show / Hide 
Range on Protein: 21-243
Range on HMM: 1-228/270
Sequence Identity: 24% (59 aa)

FELIEVVGNGTYGQVYKGRHV----KTAQLAAIKIM--NINEDE--EDEIKLEINMLKKHSHHRNVATYYGAFI-KKLPSSTGKHDQLWLVMEFCGSGSI
 ..... | | .|.||||.      .| .  |.|..  .  ...   ..   |....|.  || |.  .||. . .. |.      |...|||..  |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN------QIYIVMEYMPHGDL

TDLVKNT--KGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQL---DKT-VGRRNTFIGTPYWMAPEVIACDESPE
 |  ..    ...|. ...  .|..| .|. .|.. . ||||.   |.|.|..  ||  ||| .  .   |   . | ..      |||||.|.  .   
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGK---

ATYDSRSDLWSLGITALEMAE-GHPP-LCDMHPMRALFLI
  . . || || |..  |.   |  |   .| . . . .|
--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase mig-15.AA TyrKc 21-288 21 5.7e-15 19.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-288
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FELIEVVGNGTYGQVYKGRHVKTAQLAAIKIMNINEDEEDEIKLEINMLKKH-SHHRNVATYYGAFIKKLPSSTGKH---DQLWLVMEFCGSGSITDLVK
 .|... |.| .|.||||.     .  |.| .. .   . ..  |.....|   || |.   ||. ...           ..|..|||..  |.  |  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN----FMYIEPLMIVMEYMPHGDLKDYLR

NTKGGSLKEEWIAYICREILRGLYHLHQSKVIHRDIKGQNVLLTDSAEVKLVDFGVSAQLDKT--------VGRRNTFIGTP-----YWMAPEVIACDES
....  |. .   ..|  | .|  .||. ..||||.   |.|...   ||  ||| |  ..          . |  .  |.       |||||.|     
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----

PEATYDSRSDLWSLGITALEMAE-GHPPLCD-----MHPMRALFLIPRN---PPPKL-----KRNKKWTKKFETFIETVLVKDYHQRPYTGALLRHPFI
 . .. . || || |..  |.   | .|  .     | . ... .. .    |.|.            ...  . ...    | ..||   ..  | ..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
CNH mig-15.AA CNH 764-1067 26 8e-128 431.86 SMART 1-375 (375) Show / Hide 
Range on Protein: 764-1067
Range on HMM: 1-375/375
Sequence Identity: 26% (101 aa)

YKKKFSGEILCAALWGVNLLIGTDSGLMLLDRSGQ------GKVYPLISRRRFDQMTVLEGQNILATISGRKRRIRVYYLSWLRQK--------ILRTEG
...|.  .|.|..|||..||.||..|...|....|      |.......||....|.|.|..|.|..|||.|.......|.||.||        . ... 
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPH-IQDH

AGSANTTEKRNGW-VNVGDLQG-AIHFKI-VRYER--IKFLVVGLESSIEIYAWAPKPYHKFMSFKS----------------FGSLSHVPLIVDLTVED
..........|.| ....|..| ..|... ....|  |.||.. ...|..||.....|.|||| .||                |.....||..|......
MCNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDS

NARLKVLYGSTG------GFHAIDLD-------------SAAVYDIYTPAQSGQTT------TPHCIVVLPNSNG---MQLLLCYDNEGVYVNTYG---R
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FERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEWR

MTKNVVLQWGEMPSSVAYISTGQIMGWGNKAIEIRSVDTGHL-DGVFMHK---KAQKLKFLCE---RNDKVFFSSAK
...|..|.|..|| ..||.. ..||......|.||...||.. ....|..   |..|...||.   |..|.|..| .
RWRNPILHWEFMPEYFAYHY-PYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP
CNH mig-15.AA CNH 773-1058 22 8e-87 299.54 Pfam 1-336 (336) Show / Hide 
Range on Protein: 773-1058
Range on HMM: 1-336/336
Sequence Identity: 22% (77 aa)

LCAALWGVNLLIG-TDSGLMLLDR------SGQGKVYPLISRRRFDQMTVLEGQNILATI--SGRKRRIRVYYLSWLRQKILRT-EGAGSANTTEK----
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VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR-RVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIER

-----RNGWVNVGDLQGAIHFK--IVRYERIKFLVVGLES-----SIEIYAWAP--KPYHKF-------MSFKSFGS-LSHV----PLIVDLTVEDNARL
     ...|. ..|. ....|.   ..|.....|.. ...     .| .| |..  |..||.       ..|. |   ...     ........ .. ..
IMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLPQEKP

KVLYGSTGGFHAIDLD-SAAVYDIYTPAQSG--QTT-------TPHCIVVLPNSNGMQLLLCYDNEGVYVNTYGR-MTK--NVVLQWGEMPSSVAYISTG
|. .|.. |||...|| ... .... || .   |.        .|.|.. .... .  .|||||...||||..|. ...  .....| .|| |.|. ...
KLCVGCQKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRINDD-E-EFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFAC-CYP

QIMGWGNKAIEIRSVDTG-HLDGVFMHKKAQKLKFLCERN
.....  ..||||.|.|| ..|.....  .|...||....
YLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS