Gene ksr-2 (Nematode worm)

ksr-2

Species: Nematode worm
Alias: F58D5 7H10_03395, WP:CE31017, F58D5.4a, CD31017, ksr-2, F58D5, aSWK424, pex-1
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: I: 12067832-12055935, WormBase Genetic Map location: n/a,

Classification

Group: TKL
Family: RAF
Subfamily: RAF

Sequence

Name Sequence Type Origin Length Description Download
ksr-2.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 297 Kinase domain by global Sugen HMM Fasta, JSON
ksr-2.AA Protein Genbank 571 None Fasta, JSON

Protein domain

Protein domains of ksr-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1 ksr-2.AA C1 89-145 20 0.000127 17.64 SMART 1-61 (61) Show / Hide 
Range on Protein: 89-145
Range on HMM: 1-61/61
Sequence Identity: 20% (13 aa)

IYHKMVPSKSKFRQCDVCEHIFIFDFVRKQHLDDVYACNVCGIRVHKGCLDRVKN-------DC
. .. ..   |   |..|..  .. |      .  | | .|. ..|| |.|.| .       .|
HHWHWWRF--KPTYCCHCRKMIWGMFKQHWK-MQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_1 ksr-2.AA C1_1 124-148 24 0.000181 20.06 Pfam 31-55 (55) Show / Hide 
Range on Protein: 124-148
Range on HMM: 31-55/55
Sequence Identity: 24% (6 aa)

YACNVCGIRVHKGCLDRVKNDCKIT
. | .|. ..|. |  .|.. |.  
WKCQWCHYNCHHRCHMKVPPECGCN
Kinase ksr-2.AA RAF 269-549 48 2.9e-188 615.89 In-house 1-282 (282) Show / Hide 
Range on Protein: 269-549
Range on HMM: 1-282/282
Sequence Identity: 48% (138 aa)

VDVMTKIGDGRFGSVYFGGYHGNAAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGYVSDPVTNTYAIVTNFYQHNTLYHRIHEQLS-EDF
|.|||.||.|.||.||.|..||..||...|.|....|...||||....|..||..||..|.||.||.|.|.||||||||....|..|||.||.|.. |.|
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREKF

DQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDFALMKLERLENPRRNCTLLIPNHWIDYLSPEIAGNLMIDWRGDVLFQHELPFSQ
|..|...||.|.||.|.|||.|.|.||||...||.|.....|...||.||.......||.|.....|.|||....||...|||||||||||.|.|.|.|.
DMHWLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSF

ESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMCGQKAALQRLDAQLQKIDGKLHELLLECWSSQPEKRPSFQQIVKRITV
.|||||||....||..|.||.||..|.......|||.......|....|......|.|...||..|.|.||.||||.|||||
QSDVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV
Kinase ksr-2.AA RAF 269-547 43 8.20000000001e-166 557.15 In-house 1-275 (275) Show / Hide 
Range on Protein: 269-547
Range on HMM: 1-275/275
Sequence Identity: 43% (123 aa)

VDVMTKIGDGRFGSVYFGGYHGNAAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGYVSDPVTN-TYAIVTNFYQHNTLYHRIHEQLSEDF
|.....||.||||.||.|..||..||...||.|...| .....|..|.. .||..||..|.||.||...| .| .|||||......||||.||.| .|.|
VQIGERIGQGRFGTVYRGHWHGDVAVKTLNMKYPTPE-HQLQAFKNEVM-MYKKTRHENIVLFMGYCMKP-DNPHYAIVTQWCKGSTLYHHIHVQKTEKF

DQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDFALMKLERLENP-RRNCTLLIPNHWIDYLSPEIAGNLMIDWRGDVLFQHELPFS
|..||.||. ||||.|.|||.|.|.||||..|||.|.|...||.|||.|....|.... ||...|..|..||....||.......||  |.......|||
DMNWTIQIAQQICQGMDYLHAKNIIHRDLKSKNIFLHNGKVVVITDFGLFTVKRCRWCKRRKQQLCQPHGWICWMAPEVIRMMRPDW--DEYQCDCNPFS

QESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMCGQKAALQRLDAQLQKIDGKLHELLLECWSSQPEKRPSFQQIVKRI
..||||.|||...||.....|.....|........|.......|..|  ........|||.||||.|||.|||||||.|.|
FQSDVYAFGTVWYELMAGEWPYQHIQWHEQIIWMVCRGYLRMDRSKA-RVQCPKEMKELLMECWSYQPEERPSFQQIMKMI
Kinase ksr-2.AA KSR 269-547 36 2.6e-75 256.17 In-house 1-272 (272) Show / Hide 
Range on Protein: 269-547
Range on HMM: 1-272/272
Sequence Identity: 36% (103 aa)

VDVMTKIGDGRFGSVYFGGYHGNAAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGY-VSDPVTNTYAIVTNFYQH-NTLYHRIHEQLSED
.     || ||||.|. | .||  |..  .| ... |.  .  |  | |..||| ||. |.|| |. ...|    .|||. .    .|||| || .  | 
LKYGECIGQGRFGKVHRGHWHGEVAIKLYYMDHIHDEHHDLEDFKDE-VMMYKNTRHENIVLFMGACMNPP---HLAIVMSLCKGSQTLYHHIHVRR-EK

FDQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDFALMKLERLENP-RRNCTLLIPNHWIDYLSPEIAGNLMIDWRGDVLFQHE-LP
.| . | ||  ||||.|.||| |.|.| ||..|||...| . ||.|||.|    ||  . .|   | ||. |  || ||..  . ..  .   .| . ||
LDMNRTMQIAQQICQGMGYLHAKGIIHKDLKSKNIFYENKGKVVITDFGLFSITRLLHCCQREDHLCIPHGWLCYLAPELIRAMRPNYDE---YQCMCLP

FSQESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMCG--QKAALQRLDAQLQKIDGKLHELLLECWSSQPEKRPSFQQIVKRI
||  ||||.|||| .|.. .. |       . ....  |   .  |. . .        . |.|..|||  |. ||.||.|.| .
FSHHSDVYAFGTIWYEMICGEWPFKYQCAESIIWQMCQGEGMRQVLRNVQCGRE-----MKEILMMCWSYEPQERPTFQDIMKML
Kinase ksr-2.AA TKL 275-547 20 1.3e-62 214.3 In-house 1-364 (364) Show / Hide 
Range on Protein: 275-547
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)

IGDGRFGSVYFGGYHG-----------NAAVRFVNMNYLSQEDRRAD--------------------VFATEIVSAYKNSR--HDHIALFYGYVSDPVTN
|| |.|| || | ..|             ||   .... . ...  .                     . .|.. .   ||  |..| .|.||. .|  .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

T-----------YAIVTNFYQHNTLYHRIHEQLSEDFDQSWTFQISLQICQAMSYLHK--------KKILHRDLRTKNILLDNPNR--------------
.           ..||. .... .|.|..|         . .....|.|...|.|||         ..|.|||| .||||.|. ..              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VVVTDFALMKLERLENP---------------RRNCTLLIPNHWIDYLSPEIAGNLMIDWRG---DVLFQHELPFSQESDVYSFGTIFFELLLRRMPTG-
. ..|| | .    ..                ....|.  .  .. ...||.  . | ..     |. |......|. .|||||| ...|.| |. |   
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

CDSWDQK------LYAKMCGQKAALQRLD---------AQLQKIDGKLHELLLECWSSQPEKRPSFQQIVKRI
 .. ...      ....|...|     ..          .   ..  . .|. .||.. ||||||||.|.||.
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase ksr-2.AA Ciliate-E2 269-545 16 5.4e-23 75.76 In-house 1-361 (365) Show / Hide 
Range on Protein: 269-545
Range on HMM: 1-361/365
Sequence Identity: 16% (65 aa)

VDVMTKIGDGRFGSVYFG--GYHGN-------------------AAVRFVNMNYLSQEDRRADVFATEIVSAYK-------------NSRHDHIALFYGY
 ..  ||| | ||||| .     ..                   ... ...|..... . ..      |    .             .  |..|  .| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VSDPVTNTYAIVTNFYQHNTLYHRIHEQ-------------LSEDFDQSWTFQISL-----------QICQAMSYLHKKK-ILHRDLRTKNILLDNPNRV
  .  .|.. .|. ..|...|...| ..             ..|   .  . ||             .|..|. |||.|. |.|||.   |||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

VVTDFALMKLERLENPRRN----CTLLIPNH------------------------WIDYLSPEIAGNLMIDWRGDVLFQHELPFSQESDVYSFGTIFFEL
 ..|| | |    .| .|     | ...  .                           |..||| ..  .|       | . . . ..|..|.| |..|.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-----QKQKGYDYKCDIWSLGVILYEM

LLRRMPTGCDSWDQKLYAKMCGQKAALQRLDAQLQKIDGKLH----------------------------ELLLE----CWSSQPEKRPS-FQQIVK
|  . |                          | |....|.                              |.      .   .||||.. ..|| .
LFGKPPF-------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase ksr-2.AA TK 269-430 13 1.5e-21 68.37 In-house 1-316 (486) Show / Hide 
Range on Protein: 269-430
Range on HMM: 1-316/486
Sequence Identity: 13% (42 aa)

VDVMTKIGDGRFG---SVYFGGYHGNA----------------------------AVRFVNMNY-LSQEDRRADVFA-----------TEIVSAYKN--S
. .  |.| | ||    || | ..|                              ||  .      |||.......             |. .  ..   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHDHIALFYGYVSDPVT----------NTYAIVTNFYQHNT----LYHRIHEQLSEDFDQSWTFQ-----------------------------------
.|..|  .||.......            . ||. . .|      | .  ..   . .... . .                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------ISLQICQAMSYLHKK------KILHRDLRTKNILLDNPNR-----------VVVTDFALMK-
                                      ...||...|.|||.|      .. |||| . |.|... |.           . ..|| | . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LERLENPRRNCT
    | |  ... . .
GSGVLARDIYSDDDYY
Kinase ksr-2.AA Pkinase_Tyr 321-419 26 8.5e-21 71.06 Pfam 58-160 (270) Show / Hide 
Range on Protein: 321-419
Range on HMM: 58-160/270
Sequence Identity: 26% (28 aa)

KNS-RHDHIALFYGYVS---DPVTNTYAIVTNFYQHNTLYHRIHEQ--LSEDFDQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDF
|.  .|..|  .|| ..   .|    . ||. . .|  |..  ...    . .. ..  |...||...|.||. |.. ||||...|.|....| | ..||
KQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDF

ALMKL
 |...
GLARD
Kinase ksr-2.AA S_TKc 269-549 19 7.6e-20 73.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 269-549
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

VDVMTKIGDGRFGSVYFGGYHG---NAAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGYVSDPVTNTYAIVTNFYQH--NTLYHRIHEQL
 ... ||| | ||.|| .  ..     |.  ..           . .  ||    |  .|..|  .|..  |   . . .|. .  .   .|...|... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

SED----FDQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDFALMKLERLENPRRNCTLLIPNHWIDYLSPEIAGNLMIDWRGDVLF
..     |.  ..  .  |||.|. |.|...|.||||   |||||.  .. ..|| | ..          |.       .|..||.              
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGT---PWYMAPEVL-------------

QHELPFSQ-ESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMCGQKAALQRLDAQLQKIDGKLHELLLECWSSQPEKRPSFQQIVK-------RITV
    ...  ..|..|.| |..|.| .. |      ....  |..|               .  . ...  |.   |||||.  .. .          .
----GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ksr-2.AA MLK 269-414 22 4.2e-18 59.49 In-house 1-177 (291) Show / Hide 
Range on Protein: 269-414
Range on HMM: 1-177/291
Sequence Identity: 22% (40 aa)

VDVMTKIGDGRFGSVYFGGYHGNA------AVRFVNMNY--LSQEDRRADVFATEIVSAYKNSRHD----HIALFYGYVSDPVTNTYAIVTNFYQHNTLY
 .. ..|| | ||.|. | ....       ||. |. .    |...  .. | .|.  . . |.       |.. ..  ..|  . ..||. . ..  ||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP--CHFCIVMEYCEGGSLY

HRIHEQLSEDF------------DQSWTFQISLQICQAMSYLHKKK---ILHRDLRTKNILLDN------PNRVVVTDF
. .|.. |. .            | .  ....||. ..|.|||...   | ||||  .|||.|.         ....||
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDF
Kinase ksr-2.AA TKL-Unique 321-419 25 4.7e-15 49.69 In-house 50-166 (290) Show / Hide 
Range on Protein: 321-419
Range on HMM: 50-166/290
Sequence Identity: 25% (30 aa)

KNSR-HDHIALFYGYVSD--PVTNTYAIVTNFYQHNTLYHRIHE--------QLSEDFDQSWTFQISLQICQAMSYLHKKK--ILHRDLRTKNILLDNP-
|. . |. | ...||  |  .  . . ||. ......||  .|           . ... .   .. ..| |.| ||| ..  |.||||...|.|.||  
KKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNS

----NRVVVTDFALMKL
    ... . || | |.
NIAEWNIKICDFGLSKF
Kinase ksr-2.AA TyrKc 269-547 20 1.9e-14 10.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 269-547
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

VDVMTKIGDGRFGSVYFGGYHGNAAVRFVNMNYLSQEDRRADVFATEIVSAYKN-SRHDHIALFYGYVSDP-----VTNTYAIVTNFYQHNTLYHRIHEQ
.    |.| | || || | .  . ||  .. .           |  |.    |   .|..|  .||.....         . ||. .  |  | ..... 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

LSEDFDQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRVVVTDFALMKLERLE--------NPRR----NCTLLIPNHWIDYLSPEIAGNLM
  . .  .   ....||.. |.|||.|.. |||| . |.|......| ..|| |..    .          |     ..  ..|  |   ..||   |  
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW---MAPECI-NYG

IDWRGDVLFQHELPFSQESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKM----CGQKAALQRLDAQ--LQKIDG-----------KLHELLLECWSSQ
.             |. .|||.|||   .|..         .  |. |  |    .  . .......   . . .            ..... ..||  .
K-------------FTTKSDVWSFGVCMWEIF---------TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED

PEKRPSFQQIVKRI
||.||.|..|....
PEDRPTFSEIHECF
Kinase ksr-2.AA MLK 462-547 27 2.5e-13 42.73 In-house 210-291 (291) Show / Hide 
Range on Protein: 462-547
Range on HMM: 210-291/291
Sequence Identity: 27% (24 aa)

ELPFSQESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMCGQKAALQRLD-AQLQKIDGKLHELLLECWSSQPEKRPSFQQIVKRI
. ..|  .||.|.| .. |.| |..|       | ... ... ..|. .|  .  . ..  . .|. .||.. |.|||||.|||.  
CEKYSEKCDVWSWGVVLWEMLTREVPYK-----QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase ksr-2.AA Pkinase 269-414 23 5.7e-13 46.94 Pfam 1-156 (293) Show / Hide 
Range on Protein: 269-414
Range on HMM: 1-156/293
Sequence Identity: 23% (38 aa)

VDVMTKIGDGRFGSVYFGGYHGN---AAVRFVNMNYLSQEDRRADVFATEIVSAYKNSRHDHIALFYGYVSDPVTNTYAIVTNFYQHN----TLYHRIHE
  .  ||| | ||.|| .  .|.    ||  ..    . . ..... ..|| .  |. .|..|  .|... |   . . .|. . ..      |...|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEI-QIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

QLSEDF--DQSWTFQISLQICQAMSYLHKKKILHRDLRTKNILLDNPNRV----VVTDF
. .  |  .      . .||.... |.|...|.||||   |||.|| . .     ..||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDF
Kinase ksr-2.AA TK-Unique 373-416 36 8.3e-13 40.6 In-house 134-179 (294) Show / Hide 
Range on Protein: 373-416
Range on HMM: 134-179/294
Sequence Identity: 36% (17 aa)

FQISLQICQAMSYLHK--KKILHRDLRTKNILLDNPNRVVVTDFAL
...  ||...|.||..  ||| |||| ..|.|| . ... ..|| .
YHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGM
Kinase ksr-2.AA RIPK 315-405 28 4.5e-12 37.41 In-house 45-144 (290) Show / Hide 
Range on Protein: 315-405
Range on HMM: 45-144/290
Sequence Identity: 28% (28 aa)

EIVSAYKNSRHDHIALFYGYVSDP---VTNT-YAIVTNFYQHNTLYHRIHEQLS-EDFDQSW--TFQISLQICQAMSYLHKKK--ILHRDLRTKNILLDN
| . . .. |..||   || . ..   ..   |.||. .  .  | |  | . .  ...  |  .. .  .|  .| ||| ..  |.|||| . |||.||
EEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDN
Kinase ksr-2.AA RIPK 465-547 23 2.2e-11 34.99 In-house 205-290 (290) Show / Hide 
Range on Protein: 465-547
Range on HMM: 205-290/290
Sequence Identity: 23% (20 aa)

FSQESDVYSFGTIFFELLLRRMPTGCDSWDQKLYAKMC-GQKAALQRLDAQLQK--IDGKLHELLLECWSSQPEKRPSFQQIVKRI
.. ..|||||. . .|.| .. |   .  .. . ..   |.   || .  .  .     .. ||. .||...|..||.|| .  ..
VTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase ksr-2.AA TK 465-547 19 3.1e-11 33.14 In-house 371-486 (486) Show / Hide 
Range on Protein: 465-547
Range on HMM: 371-486/486
Sequence Identity: 19% (23 aa)

FSQESDVYSFGTIFFELLL--RRMPTGCDSW--------DQKLYAKMC-GQK---------AALQRLDAQLQKID-------------GKLHELLLECWS
|. .|||.|||   .|..   . .. |  |         .| .. . . |..             |. .  .  |               ...|...||.
FTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWH

SQPEKRPSFQQIVKRI
 .||.||.|.|.....
YDPEDRPTFSQLHEQL
Kinase ksr-2.AA TKL-Unique 522-547 38 9.2e-10 30.78 In-house 265-290 (290) Show / Hide 
Range on Protein: 522-547
Range on HMM: 265-290/290
Sequence Identity: 38% (10 aa)

LHELLLECWSSQPEKRPSFQQIVKRI
. .|. .|| ..|..||||..|..|.
YRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase ksr-2.AA TK-Unique 522-547 46 1.1e-09 29.69 In-house 269-294 (294) Show / Hide 
Range on Protein: 522-547
Range on HMM: 269-294/294
Sequence Identity: 46% (12 aa)

LHELLLECWSSQPEKRPSFQQIVKRI
...|. .||.. ||.|||| ||..|.
MYNLMKSCWQWEPEERPSFRQIKHRL
Kinase ksr-2.AA Pkinase_Tyr 521-547 33 7.1e-09 30.69 Pfam 244-270 (270) Show / Hide 
Range on Protein: 521-547
Range on HMM: 244-270/270
Sequence Identity: 33% (9 aa)

KLHELLLECWSSQPEKRPSFQQIVKRI
....|...||  .||.||.|..|. ..
EIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase ksr-2.AA TK-Unique 269-291 39 0.001855 7.93 In-house 1-23 (294) Show / Hide 
Range on Protein: 269-291
Range on HMM: 1-23/294
Sequence Identity: 39% (9 aa)

VDVMTKIGDGRFGSVYFGGYHGN
. |  .||.|.|| |..|.. |.
LEVGDVIGEGAFGQVWRGEVWGI
Kinase ksr-2.AA TKL-Unique 465-482 50 0.001993 8.16 In-house 205-222 (290) Show / Hide 
Range on Protein: 465-482
Range on HMM: 205-222/290
Sequence Identity: 50% (9 aa)

FSQESDVYSFGTIFFELL
.|. |||||||..  |..
YSEKSDVYSFGIVLWEIA
Kinase ksr-2.AA Pkinase 438-487 22 0.005393 11.67 Pfam 175-211 (293) Show / Hide 
Range on Protein: 438-487
Range on HMM: 175-211/293
Sequence Identity: 22% (11 aa)

IDYLSPEIAGNLMIDWRGDVLFQHELPFSQESDVYSFGTIFFELLLRRMP
..|..||.   ..          .  . ....|..|.| |..|.|..| |
PWYMAPEV---IR----------GGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase ksr-2.AA Pkinase 524-547 26 0.061204 7.94 Pfam 268-293 (293) Show / Hide 
Range on Protein: 524-547
Range on HMM: 268-293/293
Sequence Identity: 26% (7 aa)

ELLLECWSSQPEKRPSFQQIVKR--I
...  |.   |.|||...||..   .
DFIKWCLCKDPKKRPTAEQILQHPWF
Kinase ksr-2.AA TKL-Unique 271-290 45 0.068209 2.68 In-house 1-20 (290) Show / Hide 
Range on Protein: 271-290
Range on HMM: 1-20/290
Sequence Identity: 45% (9 aa)

VMTKIGDGRFGSVYFGGYHG
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FWNKIGEGGYGQVYKGKWRG
Kinase ksr-2.AA Pkinase_Tyr 269-284 43 1.080416 2.97 Pfam 1-16 (270) Show / Hide 
Range on Protein: 269-284
Range on HMM: 1-16/270
Sequence Identity: 43% (7 aa)

VDVMTKIGDGRFGSVY
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ITFGKKLGEGAFGEVY
Kinase ksr-2.AA Pkinase_Tyr 465-475 63 1.427724 2.56 Pfam 191-201 (270) Show / Hide 
Range on Protein: 465-475
Range on HMM: 191-201/270
Sequence Identity: 63% (7 aa)

FSQESDVYSFG
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FTTKSDVWSFG