Gene kin-9 (Nematode worm)
kin-9
Sequence
Protein domains of kin-9.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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SKG6 | kin-9.AA | SKG6 | 162-201 | 32 | 1.1e-08 | 33.58 | Pfam | 1-40 (40) | Show / Hide |
Range on Protein: 162-201 Range on HMM: 1-40/40 Sequence Identity: 32% (13 aa) KHSSEGGVNAVALGLGIGIPLGIIAFGLALFIFFWCRKRR | .. . ..|| ..|..||.| |. .| .| |.| |... KPTDKHWKTTVAIACGVVIPVGVIILVLICFLFCWWRRKK |
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Kinase | kin-9.AA | KIN6 | 303-582 | 54 | 4.5e-209 | 697.39 | In-house | 1-305 (305) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-305/305 Sequence Identity: 54% (166 aa) INYSKKLGSGAFCNVFKGKINGEAPVS-QIHPG-QRTQLLR--DCPVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKSPYLLVEFC |....|||.||||||.||||.|..|.. .|... .|....| ||..|||||||.||..|..|||.||.|||.|..|||||.|||.|.....|.|.||.| IHKDHKLGHGAFCNVYKGKIKGKSPIMQWINRVNMRIEMMRYQDCQCAVKMLPSHADEMAHHDFMHEIAFMKQLGHHPHLVNMLGCVTNSYKPCLVVEYC EHGDLLHMIRNRRQEIIN---------GPTENP--DG---LKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSAN---TCKIGDFGLCR--LTD .|.|||...|||.|...| .|.||. |. ...|||.||.|||..|.|||....|||||.|||||||.... ||||.|||||| ..| CHMDLLKYLRNRCQYMMNLDDLGINYHCPDENSRYDDMMCIRHKDLYMFAWQICDGMEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMD SLLYTARGGR-LPLKWMAPESLATYEYSYKSDVWSYGVLLWELFSLGEVPYGEVQ-TTELLQTHRSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQ ...||..||| ||.||||||.|..||.||||||||.|||..|.||||.|||.|.| .||....||||.|...|.||||||||.|..||||.|||||.| . QFQYTSKGGRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQRPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNE TCAVL . MRMQF |
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Kinase | kin-9.AA | Pkinase_Tyr | 303-582 | 41 | 4.4e-129 | 437.8 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-270/270 Sequence Identity: 41% (120 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAA--RSDFMQEINFMKSLAYHPHLVSMLGFVA-DRKS--PYLLVEF | ||||.||| .|.||. .| . ..|||||||. |.. . | |||.|.. ||.| .||..|...| . .... .|. .|. ITFGKKLGEGAFGEVYKGTWKG------------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY CEHGDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLT--DSLL-YTARGGRLPLKW ..|||||. |..| |... |..|||| ..|||..|.||| ...|||||.||||.||.. |..||.||||.|. |. ... ||.|| || MPHGDLLDYLRKHR--------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKW MAPESLATYEYSYKSDVWSYGVLLWELFSLGEVP-YGEVQTTELLQTH-RSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQTCAVL ||||........ ||||||.|||.||.|..|| | | .. .|... ..| |. .|| ||.||||.|..||.. |.||| |.. | MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | kin-9.AA | TyrKc | 303-582 | 34 | 7.70000000001e-114 | 385.41 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-280/280 Sequence Identity: 34% (109 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAARSDFMQEINFMKSL-AYHPHLVSMLGFVADR-------KSPYLL | ||||.|||. |.||. . .|||||| . | | |||.|.. |..| ||..| ..| . . . .... ITLGKKLGEGAFGEVYKGTWK-------------------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV VEFCEHGDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTDSL--------LYTAR .|...||||.. .|..| . |. |||| |.|||..| ||| .|||||.||||.||.. .|.||.||||.| .. |... MEYMPHGDLKDYLRKHRPK-----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKK ---GGR--LPLKWMAPESLATYEYSYKSDVWSYGVLLWELFSLGEVPYGE-----VQTTELLQTHRSGKRLLKPEW--------CPEEIYDVMRLCWQEL ||. ||..|||||.. ..... ||||||.||..||.|..|. || . . .|... ..|.|. .|. ||.|.|..|. ||.| EHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHED PDDRPAFQQTCAVL |.||| |.. . . PEDRPTFSEIHECF |
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Kinase | kin-9.AA | TK | 303-582 | 22 | 6.8e-103 | 345.83 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-486/486 Sequence Identity: 22% (111 aa) INYSKKLGSGAFC---NVFKGKINGEAP--VSQIHPGQR-TQLLRD------CPVAVKMLPSF--ADDAARSD--------------FMQEINFMKS-LA | . ||||.|.|. |.||. .|. | .. .. .. |. ... .||||||| . ...... | ...|. |.. | ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG YHPHLVSMLG-------------FVADRKSPYLLVEFCEHGD----LLHMIRNRRQEIINGPTENPD--------------------------------- ||..|...| . ... .....|...||| |.. |..| . .. . .... HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD -------------------------------GLKIKDLLMFSWQISNGLEYLNNI------GCIHRDIAARNVLVDSANT-----------CKIGDFGLC | ..|| ..|||..|.||| ...|||.||||.||.. |. |||.||||. YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS R-----LTDSLL-----YTAR------------------------GGRLPLKWMAPESLA---------TYEYSYKSDVWSYGVLLWELFSLGEVPYGEV | |. . |... ||.||..|||||.|. . .. ||||||.|||.||.|..|..||.. RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG QT----------TELLQTHRSG--------------KRLLKPEWCP--------------EEIYDVMRLCWQELPDDRPAFQQTCAVL . .|... |.| |. .|. || ||.||.|. ||.. |.||| |.| | MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | kin-9.AA | TK-Unique | 303-582 | 34 | 1.7e-90 | 306.98 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-294/294 Sequence Identity: 34% (106 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRK-SPYLLVEFCEHG .. ...|.||| |..|.. | . .. |||||| |.| ..||..||..||.| .||..|..|| . ..... |.|. | LEVGDVIGEGAFGQVWRGEVWGIW----------KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCG DLLHMIRNRRQE--------IIN------GPTENPDGLKIKDLLMFSWQISNGLEYLNN--IGCIHRDIAARNVLVDSANTCKIGDFGLCR-LTDSLLYT .|.| .|..|.. ... .. ... .. |||. | ||| .|.||| ...|||..|||||. . ..|||.|||. | . . | NLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYS ARG--GRLPLKWMAPESLA--TYEY-SYKSDVWSYGVLLWELFSLGEVPYGEVQTTELLQTHRSGKRLLKPEWC-PEEIYDVMRLCWQELPDDRPAFQQT . ||.|..||||||| . | ..||||||.|||.||.|.||. ||... ..... | |.|...|| | ..|.| .|. |||. |..|| | | MMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQI CAVL .| KHRL |
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Kinase | kin-9.AA | UTK | 303-582 | 27 | 1.1e-81 | 277.62 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-296/296 Sequence Identity: 27% (88 aa) INYSKKLGSGAFCNVFKGKIN------GEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAARS--DFMQEIN---FMKSLAYHPHLVSMLGFVADRKSP . ...||.||| .|.|.. . .|. |.. ..| .. .. ||| | . .|| .. ||... ..| . . . . VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---------------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPW YLLVEFCEHGDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSA-------NTCKIGDFG---LCRLTD-- ....|..| |||... |. |.. ..|. |. ..| ..|.|..|..|| . |..|||.||||.||.. ..|||.||| ..|. MIVTEYMENGDLRSYLRRHRPTPP----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTF --------SLLYTARG-GRLPLKWMAPESLATY-EYSYKSDVWSYGVLLWELFSLGEVPYGEVQTTELLQTHRSG--KRLLKPEWCPEEIYDVMRLCWQE |..|.|.. .|.|..|||||.|. .. ||||||.||..||... | .||.. . .... . | |. .|. ||...|..|. ||. HFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHY LPDDRPAFQQTCAVL |..|| |.. ... DPQERPDFEDLVQQM |
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Kinase | kin-9.AA | Fer | 303-583 | 29 | 2.1e-76 | 259.66 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 303-583 Range on HMM: 1-283/283 Sequence Identity: 29% (89 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLL-RDCPVAVKML-PSFADDAARSDFMQEINFMKS-LAYHPHLVSMLGFVADRKSPYLLVEFCE .. ||||.|||. |.||. . .. . ... ....|.||.. ..|... . .||.| ..|.. . ||. | |. .|. ... ||| VTLGKKLGEGAFGEVYKGR-------RTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYD-HPNVVKFYGVCVDEQPIMIVMEFCN HGDLLHMIRNRRQEIINGPTENPDG-LKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDS-ANTCK--IGDFGLCRLTDSLLYTAR-G---GRLP .|.|. .. .|.. ....... .. |...|.||| .||||||||||.|.. . .| | |||..| .. |. . . ..| GGSLDSYLK-----------KNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVP LKWMAPESLATYEYSYKSDVWSYGVLLWELFSLGEVPYGE----VQTTEL-----LQTHRSGKRLLKPEWCPEEIYDVMR-LCWQELPDDRPAFQQTCAV .|.|||.. | .||.|.||||.||..|| |. |. ||.. .. |.. . ..|... |. .|.||. .| |||. |.||| ... | IRWLAPETWQTGIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQK LA | LK |
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Kinase | kin-9.AA | RTKB | 303-582 | 37 | 6.5e-74 | 248.55 | In-house | 1-264 (264) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-264/264 Sequence Identity: 37% (105 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQR-TQLLRDCPVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKSPYLLVEFCEHG . .|||.||| .||.. . .... .|. .|.| |. | .| || .|. .|| | ||... ..| . ||||.||.| VWLGEKLGNGAFGEVFQAWVR--------NRHMNTEQS-----CAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELG DLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTDSLLYTARGGRLPLKWMAPESLA | | .|. . .|| || . |. |. || .| .| . |||| .|||||||. .||| |||. | | |. ||| |||||||.| NLRDYLRMCRA-----SQHNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWA TYEYSYKS-DVWSYGVLLWELFSLGEVPYGEVQTTELLQTHRSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQTCAVL |. || ||||.|| || |||| .|| . .. .... .|| || ||. | .....|. |||. ...||.|. . . HRIYTTKSGDVWSFGVTMWEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF |
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Kinase | kin-9.AA | Src | 344-582 | 36 | 3.4e-71 | 241.12 | In-house | 25-255 (255) | Show / Hide |
Range on Protein: 344-582 Range on HMM: 25-255/255 Sequence Identity: 36% (89 aa) PVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKSPYLLV-EFCEHGDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLE .|||| | . . .| ||.. ||.| |..||... . . . |.. | |. .|| || .. .. |....|. ...|...| . KVAVKTLKPGT--MSPEAFLQEAQIMKKLR-HEKLVQLYAVCSQEE-PIYIVTEYMSHGSLLDYLKK---------DGEGRHLHLPQLIDMAAQVAEGMA YLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTD--SLLYTARGG-RLPLKWMAPESLATYEYSYKSDVWSYGVLLWELFSLGEVPYGEVQTTELLQ || |||| |||||||. | ||..|||| ||.. |.|| | ..| ||.||| . .. ||||||.|.||.|... | ||| . | || YLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQ THRSGKRLLKPEWCPEEIYD-VMRLCWQELPDDRPAFQQTCAVL | |. .|. ||.|.|. .|. ||.. |..|| | . .| QVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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Kinase | kin-9.AA | Met | 344-576 | 35 | 1.5e-68 | 223.78 | In-house | 28-271 (271) | Show / Hide |
Range on Protein: 344-576 Range on HMM: 28-271/271 Sequence Identity: 35% (90 aa) PVAVKMLP--SFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKS--PYLLVEFCEHGDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISN ..|.| | | . | | | || . ||. | .| | . |. . .. .||||.. ||| .. ...||. | |. HCACKSLHGERITDIQHISQFLREGIMMKHFD-HPNVLSLIGICLDPEGHMPWVVLPYMKHGDLKTFIRNPQNNP-----------CVRDLIEFCHQVAK GLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLT--DSLLYTA---RG-GRLPLKWMAPESLA--------TYE-YSYKSDVWSYGVLLWELFSL | .|. .||| |.|| . | | |..|||||| | .| . .. |||.||||||.| || .. |||||| ||..|||. GMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVMWELMTR GEVPYGEVQT-TELLQTHRSG--KRLLKPEWCPEEIY-DVMRLCWQELPDDRPAFQ | .||..| . . .. | .||..|| ||. .| ||| ||. | ||| | GAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS |
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Kinase | kin-9.AA | FGFR | 303-582 | 35 | 7.1e-66 | 223.51 | In-house | 1-293 (293) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-293/293 Sequence Identity: 35% (108 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKSPYLLVEFCEHGD | || |.| | .. .| .. . . |||||| . . | || |. || |. . || .| .||.|.|| LTLGKMLGEGCFGQVWMAEAKGI---------DCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGN LLHMIRNRRQEI------IN-------GPTENP------DGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTDSLLY | | || .. ..| . | ||| . .|. | ||| ||||| ||||||| . || |||| | .. | LRDFLRARRPPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDY --TARGGRLPLKWMAPESLATYEYSYKSDVWSYGVLLWELFSLGEVPYGEVQ-TTELLQTHRSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQTCA |||| ||||||.| | .|||||||||||| . .|. || . || . ..|.|. ||. |..||| .|. || . |..|| | | YRKTTNGRLPIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVE VL | YL |
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Kinase | kin-9.AA | VEGFR | 425-582 | 45 | 1.2e-59 | 204.45 | In-house | 170-332 (332) | Show / Hide |
Range on Protein: 425-582 Range on HMM: 170-332/332 Sequence Identity: 45% (75 aa) LKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRL---TDSLLYTARGG--RLPLKWMAPESLATYEYSYKSDVWSYGVLLW | .||. .| |. .| |.| ||||| ||||.|... |. || |||| | .| | ..|. |||.|||||||. |. .||||||||.|| LTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDP-DYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFLW ELFSLGEVPYGEVQ-TTELLQTHRSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQTCAVL | |||| .|| || |. . ..| |. .|. |. |||..| || . | ||.| .| EIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL |
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Kinase | kin-9.AA | S_TKc | 303-586 | 23 | 1.7e-43 | 151.73 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 303-586 Range on HMM: 1-231/231 Sequence Identity: 23% (69 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVADRKSPYLLVEFCEH-- .|.|.||| |.|.. .. . ||.|... ....||. .|. ||..| .... | .. |. |.|.. YEILRKIGKGAFGKVYKCRHKK----------------TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDL GDLLHMIRNRRQEIINGPTENPDGLKIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTCKIGDFGLCRLTDSLLYTARGGRLPLKWMAPESL |||...|..|. . .. .. . . .|| ..|||. . | ||||. |.|.|. . ||.||||.|. . . .|||| | GDLFDYIKKRGRH------GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL ATYEYSY-KSDVWSYGVLLWELFSLGEVPYGEVQTTELLQTHRSGKRLLKPEWCPEEIYDVMRLCWQELPDDRPAFQQTCA-----VLAQML |.. |.|.|| |..|.|... |. |. | .... . ..| | .| |.| |..|| . . . . . ---GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | kin-9.AA | Pkinase | 303-582 | 23 | 6.5e-37 | 131.61 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 303-582 Range on HMM: 1-293/293 Sequence Identity: 23% (77 aa) INYSKKLGSGAFCNVFKGKINGEAPVSQIHPGQRTQLLRDCPVAVKMLPSFADDA--ARSDFM-QEINFMKSLAYHPHLVSMLGFVADRKSPYLLVEFCE . .|.|||.| |.|.. |. |||| .. .. .... .|| ||.| ||. | ..... |....|. |.|| YHIGRKIGSGSFGCVYKCHHKGTGK----------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCE HG----DLLHMIRNRRQEIINGPTENPDGL--KIKDLLMFSWQISNGLEYLNNIGCIHRDIAARNVLVDSANTC----KIGDFGLCR---LTDSLLYTAR .| || ..|. .. .. ... .. .|| ||||. . |.||||. |.|.|. ... ||.||||.. . . .| . GGLYVMDLFDYIST----------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF GGRLPLKWMAPESLA-TYEYSYKSDVWSYGVLLWELFSLGEVPYGEV----QTTELLQTHRSGKR----LLKPEWCP-------------------EEIY | .. .|||| . .|..|.|.||.|..|.|... |. |. . . .| .. .. |.||. || CGTPW--YMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECK DVMRLCWQELPDDRPAFQQTCAV--L |... |.. | .|| ..| . . DFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | kin-9.AA | Src | 303-328 | 42 | 6.4e-05 | 12.61 | In-house | 1-26 (255) | Show / Hide |
Range on Protein: 303-328 Range on HMM: 1-26/255 Sequence Identity: 42% (11 aa) INYSKKLGSGAFCNVFKGKINGEAPV | .|||.| | |..|. ||. .| IKLCRKLGQGQFGEVWMGYWNGNTKV |
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Kinase | kin-9.AA | VEGFR | 345-413 | 30 | 0.001935 | 9.07 | In-house | 32-103 (332) | Show / Hide |
Range on Protein: 345-413 Range on HMM: 32-103/332 Sequence Identity: 30% (22 aa) VAVKMLPSFADDAARSDFMQEINFMKSLAYHPHLVSMLGFVAD--RKSPYLL-VEFCEHGDLLHMIRNRRQE |||||| . |. | |. .. . | |..|| . | |.. ||.| .| |. | |.. VAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTKRMY |