Gene kin-31 (Nematode worm)
kin-31
Sequence
Protein domains of kin-31.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| SH2 | kin-31.AA | SH2 | 20-101 | 31 | 1.3e-31 | 94.67 | Pfam | 1-81 (81) | Show / Hide |
Range on Protein: 20-101 Range on HMM: 1-81/81 Sequence Identity: 31% (27 aa) YFHGLIQREDVFQLLDN----NGDYVVRLSDPKPGEPRSYILSVMFNNKLDENSSVKHFVINSVENK-YFVNNNMSFNTIQQMLSHY ..|| |.|... .|| | .|...|| |. .||. | |||..... ...|||..|.. .|. |.. . |...|.. .|| WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGD---YTLSVRDDGP---GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY |
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| SH2 | kin-31.AA | SH2 | 18-107 | 29 | 1.2e-25 | 92.41 | SMART | 1-87 (87) | Show / Hide |
Range on Protein: 18-107 Range on HMM: 1-87/87 Sequence Identity: 29% (29 aa) EAYFHGLIQREDVFQLLDNN----GDYVVRLSDPKPGEPRSYILSVMFNNKLDENSSVKHFVINSVE-NKYFVNN--NMSFNTIQQMLSHYQKSRTE . ..|| | ||.. ||| |. ||..|| |.. .|..|.|||... . |||..|.. . .||.. ...|... ... |||. . QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSES---NPGDYVLSVRWK------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG |
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| Kinase | kin-31.AA | Fer | 130-384 | 45 | 2.1e-145 | 489.36 | In-house | 1-283 (283) | Show / Hide |
Range on Protein: 130-384 Range on HMM: 1-283/283 Sequence Identity: 45% (129 aa) IVIEKKLGEGAFGEVSSG--VMKFKRGGRLV----KVAVKQVKTDGIGKDQIKDFLMEARTMRN-LGHPNIVRFLGIAVLQEPLFLVMELATGGALDSYL ....||||||||||| .| ..|.|.|...| .|.|| .|... .|.|||.|. ||| ||| . |||.|.| |..|...|. .|||...||.||||| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL KHNEL--LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGKVK----ISDFGLTRR----GTIYQLH-PETKSPIRWLAVETIRTMVCSQKTD |.|. ........|..|||.|.||.|.| ..|||||||||||...||| |||||. | |. |... ...| |||||| ||..|...| ||| KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD VWAYGILCWEIFNNGAEPYPG----LTANEV-----AKQVTDGYRMPPHQLAAPEVQALMT-RCCAENPNDRPTMSDVAQILQ ||..|..|||||.|||||||| .....| .. ...||.||. . ..||. .|. .|....|.|||||... |.| VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK |
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| Kinase | kin-31.AA | TyrKc | 130-383 | 38 | 2.6e-117 | 396.95 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 130-383 Range on HMM: 1-280/280 Sequence Identity: 38% (112 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNL--GHPNIVRFLGIAVLQ-------EPLFLVMELATGGALDS |. .||||||||||| |..| ..|||| .| | ..||. ||| |..| ||||||..|... | |||..|||.. .|.|.. ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD YLKHNEL-LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGK-VKISDFGLTRRGTIY--------QLHP----ETK--SPIRWLAVETIRTM ||. .. |. .. ... .|.| | ||.| |. |||.||||||.|... ||||||||.| .. . .. .| ||||.| |.|.. YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG VCSQKTDVWAYGILCWEIFNNGAEPYPG-----LTANEVAKQVTDGYRMPPHQL--------AAPEVQALMTRCCAENPNDRPTMSDVAQIL ... |.|||..|...|||| .|..|||| ... || ..| .|||||. . . .|. .|..|..|.|.||||.|.. ... KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF |
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| Kinase | kin-31.AA | Pkinase_Tyr | 130-383 | 40 | 6.5e-116 | 393.2 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 130-383
Range on HMM: 1-270/270
Sequence Identity: 40% (109 aa)
IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQ--IKDFLMEARTMRNL-GHPNIVRFLGIAV-LQEP--LFLVMELATGGALDSYLK
|.. ||||||||||| |..| . .. ..|||| . .| ..| ..||. ||..|..| ||||||..|. . .|| ...|||.. .| |..||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR
H----NELLPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYG-DGKVKISDFGLTRRG-----TIYQLHPETKSPIRWLAVETIRTMVCSQKTDVW
.. |.. .| .| |.|.|| . |.. |||.|||||| . ...|||.||||.| |. . ..| ||.|.| | |...... |.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW
AYGILCWEIFNNGAEP-YPGLTANEVAKQV-TDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQIL
..|.|.|||| |..| |||.. .|| ... ||||||. ... .|. ||..| ...|.||||.|.. ..|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
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| Kinase | kin-31.AA | TK | 130-383 | 22 | 6.1e-98 | 328.95 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 130-383
Range on HMM: 1-486/486
Sequence Identity: 22% (111 aa)
IVIEKKLGEGAFG---EVSSG-------------------VMKFKRGGRL--VKVAVKQVK--TDGIGKDQIK----------DFLMEARTMRNLG----
|...||||||.|| || | ..|.|.|.. ..||||..| .. .... |||.||. | .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HPNIVRFLG-------------IAVLQEPLFLVMELATGGA----LDSYLKHNEL--------------------------------------------
||||||..| . |.|||. .|||.. .| |..||. .
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD
--------------------------------LPIDKRHEMLLQAAWGLEYIHGKP------MLHRDIAARNCLYGDGK------------VKISDFGLT
|. .. | .|.| |.||.| |. . |||.|||||| |... .||.||||.
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
R-----------RGTIYQLHP------------------------ETKSPIRWLAVETIR---------TMVCSQKTDVWAYGILCWEIFNNGAEPYPGL
| ... | . .| ||||.| |... . ... |.|||..|.|.|||| .|.|||.|
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG
TAN----------EVAKQVTDG--------------YRMPPHQLAA--------------PEVQALMTRCCAENPNDRPTMSDVAQIL
| || .....| .|||. ... .|.. ||..|....|.||||.|.. . |
MSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | kin-31.AA | UTK | 130-383 | 31 | 8.5e-83 | 281.37 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 130-383 Range on HMM: 1-296/296 Sequence Identity: 31% (94 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLV-KVAVKQVKTDGIGKDQIK---DFLMEAR---TMRNLG-HPNIVRFLGIAVLQEPLFLVMELATGGALDSY . . ..||.||||||. . .. .. ... .||||. .... . .. ||..||| | .. |||..|..|. . .||. .|.|.. .| |.|| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LK--------HNELLPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDG--------KVKISDFG---LTRRGT------------IYQLHPETK | . ..| ..| .| .. | |..|.|.. |||.|||||| .. ..||.||| ..|| |. .. .. LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR SPIRWLAVETIRTM-VCSQKTDVWAYGILCWEIFNNGAEPYPGLTANEVAKQVTDG--YRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQIL |||| | | . . ..|.|||..|..||||. .|. ||||... .|..||..| ||||. . .| ||.||.. .| .||.. |. | . WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | kin-31.AA | TK-Unique | 130-383 | 32 | 1.9e-62 | 213.79 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 130-383
Range on HMM: 1-294/294
Sequence Identity: 32% (97 aa)
IVIEKKLGEGAFGEVSSGVMKF--KRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLG-HPNIVRFLGIAVLQ-EPLFLVMELATGGALDSYLKHN
.......||||||.| | .. | .. ..||||..| |. . . .||| |.. |..|| |||||..||. . || ...|| . .| |..||. .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLK-DNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC
ELL-----------------PIDKRHE--M---LLQAAWG----LEYIHG--KPMLHRDIAARNCL-YGDGKVKISDFGLTR----RGTIYQLHPETKSP
| ..| | . |.. ||. .||... | |||..|||.| .|...||.|||..| .| . . . |
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIP
IRWLAVETIR--TMVC-SQKTDVWAYGILCWEIFNNGAEPYPGLTANEVAKQVTDGYRMPPHQLA-APEVQALMTRCCAENPNDRPTMSDVAQIL
|||.| | .. . .. . |.|||..|.| |||| .|| ||||. . .. ....|||||| . .|. || .| ..| .||. ......|
IRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
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| Kinase | kin-31.AA | Abl | 130-383 | 37 | 8e-62 | 204.84 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 130-383 Range on HMM: 1-252/252 Sequence Identity: 37% (96 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGGALDSYLKHN--EL |....||| | .||| || | |||| .| | . ....|| || |... |||.|. ||. | ... | . | | ||... |. IMMKHKLGGGQYGEVYEGVWKRHD----CTVAVKTLKEDTM---EVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREE LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGK-VKISDFGLTR--RGTIYQLHPETKSPIRWLAVETIRTMVCSQKTDVWAYGILCWEIFN || | | | |..|. . .|||.|||||| |. . ||. ||||.| .. .| | | ||.| | | . | | ||||.|.| ||| LPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIAT NGAEPYPGLTANEVAKQVTDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQIL | ||||. ..| ... .|||| . |.| || .| .. |||. .. . . YGMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM |
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| Kinase | kin-31.AA | Src | 130-383 | 35 | 2.4e-59 | 200.25 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 130-383 Range on HMM: 1-255/255 Sequence Identity: 35% (94 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGGALDSYLK---HNE | ..|||.| |||| |. . . .||||| | . . ..|| || .| .| |...|. . . || . | |. . | | ||| IKLCRKLGQGQFGEVWMGYWNGN-----TKVAVKTLKPGT---MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGR LLPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGK-VKISDFGLTRRGT----IYQLHPETKSPIRWLAVETIRTMVCSQKTDVWAYGILCWE |.. . .| | | | .|. . . ||| |||| | |.. .|. |||| | .| . . | ||.| | | |. . ..|.||| .||| .| HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTE IFNNGAEPYPGLTANEVAKQVTDGYRMPPHQLAAPEVQA-LMTRCCAENPNDRPTMSDVAQIL |. | |||| | || .|| ||||| . .|. .|..| . | .||| . | IVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | kin-31.AA | TKL | 136-383 | 21 | 2.4e-54 | 186.86 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 136-383
Range on HMM: 1-364/364
Sequence Identity: 21% (79 aa)
LGEGAFGEVSSGVMKFKRGGRL-----VKVAVKQVKTDGIGKDQI-------------------------KDFLMEARTMRNLGHPNIVRFLGIAVLQEP
.|.|.|||| |. . .| . ||||. |.. .. . . . |.. |..| |||||.|.|.. ..
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC
-------------LFLVMELATGGALDSYLKHNELLPIDKRHEMLLQAAWGLEYIHG--------KPMLHRDIAARNCLYG-DGK--------------V
|..|||.. || | .|| ...|. . |..| |..| | .|..|||. .|.| ... .
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC
KISDFGLTRRGTIYQ--------------------LHPETKSPIRWLAVETIRTM----------------VCSQKTDVWAYGILCWEIFNNGAEPYPGL
||.|||| |. . . . .||.| | .| . |.|.||...||. |||. || ..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-PYYDY
TANEVA---------KQVTDGYRMPPHQ-------------LAAPEVQALMTRCCAENPNDRPTMSDVAQIL
... ..| | . || . |.. ||..|....|..||..... ..|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
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| Kinase | kin-31.AA | Ack | 130-383 | 33 | 3.7e-54 | 181.08 | In-house | 1-266 (266) | Show / Hide |
Range on Protein: 130-383 Range on HMM: 1-266/266 Sequence Identity: 33% (91 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKD-QIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPL-FLVMELATGGALDSYLKHNEL | .|||.| || | |. . || . |||| .. | . . ||| |. .| .| ||..|| |. || |. .|.|||..|.| |. ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGV-VLDQPMLMMVTELAPCGSLLDCLRKHCR ---LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDG--KVKISDFGLTRR----GTIYQLHPET--KSPIRWLAVETIRTMVCSQKTDVWAYG ..| .. ..| | |. | . | ..||| |||| | . ||||.|||| |. | . | |. | |.| .|. | . |||..| TAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFG ILCWEIFNNGAEPYPGLTANEVAKQVT-DGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQIL || | | ||. |... .. ... .| | | . ... ..| .| ...| |||| |.. | VTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL |
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| Kinase | kin-31.AA | Frk | 130-387 | 33 | 2.3e-52 | 179.72 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 130-387 Range on HMM: 1-260/260 Sequence Identity: 33% (89 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGGALDSYLK----HN | . ..|| | |||| | . . ||||..|. | .||| ||. |..| || ... . ..||.... || |.| ||. . IQLIRRLGSGQFGEVWEGLWNNT-----TPVAVKTLKP---GTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKG ELLPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGK-VKISDFGLTR---RGTI--YQLHPETKSPIRWLAVETIRTMVCSQKTDVWAYGILC . . . . .| | | |. |. . .|||.|||| | |... .|| |||| | . . | . . . ||.| | | ... . | |||..||| RQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILL WEIFNNGAEPYPGLTANEVAKQVTDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQILQRVT || | ||||.| || ..| ||||| ... .| | ..|. ||| . |. TEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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| Kinase | kin-31.AA | Syk | 130-377 | 34 | 1.1e-51 | 176.17 | In-house | 1-257 (257) | Show / Hide |
Range on Protein: 130-377 Range on HMM: 1-257/257 Sequence Identity: 34% (88 aa) IVIEKKLGEGAFGEVSSGVMKFK---RGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGGALDSYLKHN- .| . .| | || | .|. . | ....|||.| | |. . . . |. || | | || ||| .||. . |.. .|||.| .|.. ||. . LVQDNEIGCGNFGSVHKGWYMMKSGAGEKQWIKVAIKMLKADHNQPADKQEFMREAQVMCQLDHPCIVRMIGIC-HAEMMMMVMEMAELGPMHKYLQQHR ELLPIDKRHEMLL-QAAWGLEYIHGKPMLHRDIAARNCLYGD-GKVKISDFGLTR----RGTIYQLHPETKSPIRWLAVETIRTMVCSQKTDVWAYGILC . . |.. | | | | .| ||| |||| | . . ||||||. . . || | |..| | | | | | ||| .|.. HEITANNVLELWHTQVAMGMCYLEEKHFVHRDLAARNVLLVNRHYAKISDFGMSKALGADSQYYQATTHGKWPVKWYAPECIYYYKFSHKSDVWSFGVTM WEIFNNGAEPYPGLTANEVAKQVTDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMS || | |. || . . || |.. | ||. . .|. .|| .| . . |||| . WEMFSYGQKPYGEMKGQEVMKFIENGHRMNCPNGCPQEMYQLMNKCWIYKWCDRPTFV |
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| Kinase | kin-31.AA | S_TKc | 130-387 | 23 | 1.5e-42 | 148.57 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 130-387
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)
IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQIKDFLMEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATG--GALDSYLKHNEL
| .|.|.||||.| .. | .||.|..| .... | . ... .|||||..... . . |..|||.. | | | .|.|..
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR
------LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYGDGKVKISDFGLTRRGTIYQLHPETKSPIRWLAVETIRTMVCSQ-KTDVWAYGILCW
.| .. | . .|||.| . .|||. | | . .||.|||| |. ..| | . . | |.|. |.. .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY
EIFNNGAEPYPGLTANEVAKQVTDGYRMPPHQLAAPEVQALMTRCCAENPNDRPTMSDVAQ-----ILQRVT
| . | |.| . ... |.. ||. .. .|. .|..||| .. | .
EMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | kin-31.AA | Pkinase | 130-386 | 23 | 1.1e-39 | 141.42 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 130-386 Range on HMM: 1-293/293 Sequence Identity: 23% (71 aa) IVIEKKLGEGAFGEVSSGVMKFKRGGRLVKVAVKQVKTDGIGKDQ-IKDFL-MEARTMRNLGHPNIVRFLGIAVLQEPLFLVMELATGG----ALDSYLK ..|..|.|.|.||.| .. | . .||||..| ... ... . ... .|.. |..|.||||||.... . .|||.. || | .|.. YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS ---HNEL-LPIDKRHEMLLQAAWGLEYIHGKPMLHRDIAARNCLYG-DGKV----KISDFGLTRR--GTIYQLHPETKSPIRWLAVETIR-TMVCSQKTD |. . .. . ...| . ||||.| . .|||. |.|. .| . ||.|||| . .. ....| | || ..| | TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD VWAYGILCWEIFNNGAEPYPGL------TANEVAKQVTDGYRMPPHQ--------------------LAAPEVQALMTRCCAENPNDRPTMSDVAQILQR .|..|....| .. | |.|| . ... ... .. . . . .. .| . ....|.. .|..||| .|||| MWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQH --V . PWF |
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